Esteroides
Revisado por pares por Dr Colin Tidy, MRCGPÚltima actualización por Dra. Toni Hazell, MRCGPLast updated 26 Mar 2023
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En esta serie:Inyecciones de esteroidesOral steroidsTopical steroidsUnidades de yema de dedo para esteroides tópicosAerosoles nasales de esteroides
Los medicamentos esteroides se utilizan para muchas condiciones médicas diferentes. Los esteroides pueden administrarse en forma de cremas/ungüentos (por ejemplo, para eccema o dermatitis), como spray nasal (por ejemplo, para fiebre del heno o rinitis alérgica), como inhaladores (por ejemplo, para asma), en tabletas (por ejemplo, para enfermedad inflamatoria intestinal) o como inyección (por ejemplo, para artritis).

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What are steroids?
Steroids are hormones that occur naturally in the body. Steroid medicines are man-made and are similar to the natural hormones made in the body. The type of steroids used to treat disease are called corticosteroids. They are different to the anabolic steroids which some athletes and bodybuilders use. Anabolic steroids have very different effects.
Types of steroids
Volver al contenidoSteroids come in many different forms. The main types of steroids are:
Oral steroids
Oral steroids reduce inflammation and are used for treating many different conditions, including:
Asma.
Artritis.
As part of the treatment for various cancers.
See also the separate leaflet called Oral Steroids.
Topical steroids
Topical steroids are used on the skin. See also the separate leaflet called Topical Steroids (excluding Inhaled Steroids).
Topical steroids used for the skin are available as creams, ointments or lotions. Topical steroids are used for various skin conditions. The amount of topical steroid that you should apply is commonly measured by fingertip units. For more information see the separate leaflets called Topical Steroids for Eczema y Fingertip Units for Topical Steroids.
Steroids can also be given as:
Eye drops to reduce inflammation on the surface of the eye such as caused by uveítis. These should only ever be started by a specialist eye doctor (ophthalmologist) who will usually have used a machine called a slit lamp to look into the back of your eye first.
Rectal foam or suppositories to treat ulcerative colitis (proctitis) or for enfermedad de Crohn affecting the rectum.
Aerosoles nasales de esteroides
Steroid nasal sprays are medicines that are commonly used to treat symptoms of stuffiness or congestion in the nose. They are used most often for allergies of the nose, such as hay fever. They can be bought over the counter at a pharmacy - in general, treatment of fiebre del heno should usually be bought over the counter rather than asking your GP for a prescription. See also the separate leaflet called Steroid Nasal Sprays.
Steroid inhalers
Steroid inhalers are steroids that are breathed in and down into your lungs. Inhaled steroids are mainly used to treat asthma and chronic obstructive pulmonary disease (COPD). For more information see the separate leaflets called Inhalers for Asthma (including Inhaled Steroids) y Inhalers for COPD (including Inhaled Steroids).
Inyecciones de esteroides
Steroid injections can be used for joint problems and rheumatoid arthritis. They can also be used for some conditions affecting soft tissues, like tendon inflammation or tennis elbow. They can sometimes be given at the GP practice, if there is a doctor, nurse or physio there who has had special training to do this. In more complicated situations they may be given in a hospital, using ultrasound guidance. For more information see the separate leaflet called Steroid Injections.
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How do steroids work?
Volver al contenidoSteroids are a man-made version of hormones normally produced by the adrenal glands, which are just above each kidney. When taken in doses higher than the amount your body normally produces, steroids:
Reduce inflammation
Inflammation occurs when the body's immune system responds to injury or infection. When this affects the skin and tissues under the skin then the area can become painful, hot, red and swollen. Inflammation usually helps to protect you but sometimes inflammation can cause harm to your body. Steroids can help to treat inflammatory conditions such as asma y eccema - they are a type of anti-inflammatory drug.
Reduce the activity of the immune system
The immune system is the body's natural defence against illness and infection. This can help treat autoimmune conditions, such as artritis reumatoide, hepatitis autoinmune o lupus eritematoso sistémico (LES), which are caused by the immune system mistakenly attacking the body.
Side-effects of steroids
Volver al contenidoSteroids don't tend to cause significant side-effects if they're taken for a short period of time or at a low dose. Side-effects are much more common with oral steroids or if you take them for a long time.Side-effects can include:
Increased appetite, which may cause weight gain.
Difficulty sleeping (insomnio).
Increased risk of infections, especially viral infections such as herpes zóster o sarampión.
síndrome de Cushing due to excessive steroid in the body, which can lead to various effects on the body, including thinning of the skin, easy bruising and stretch marks.
Mental health problems, including:
Changes in mood (mood swings) and behaviour - eg, feeling irritable or anxious.
A short course of steroids can be taken and then stopped, but if using them for a long time, they must be slowly tapered off rather than stopping suddenly. Speak to your doctor if you are unclear about whether you need to taper your steroids - generally speaking if you have been taking them for more than a week or two, this might be necessary.
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Tratamiento y medicación
Oral steroids
Los medicamentos esteroides (a veces llamados corticosteroides) son versiones sintéticas fabricadas por el hombre de las hormonas esteroides producidas por el cuerpo. Existen varias formas diferentes de medicamentos esteroides. La forma que se discute en este folleto es la forma en tableta, que se toma por vía oral, llamada esteroides orales. Otros tipos de esteroides incluyen cremas, ungüentos, inyecciones, inhaladores y aerosoles. Estos se abordan en los folletos separados llamados Esteroides tópicos (excluyendo esteroides inhalados), Esteroides tópicos para eccema e Inhaladores para asma.
por la Dra. Philippa Vincent, MRCGP

Tratamiento y medicación
Medicamentos y tratamiento para la demencia
Los objetivos del tratamiento para las personas con demencia son frenar el empeoramiento de los síntomas, mantener la función y promover la independencia. Los medicamentos para la demencia se utilizan para ayudar con los síntomas que afectan el pensamiento y la memoria, así como los síntomas que afectan el estado de ánimo y el comportamiento. Pero también existen muchos tratamientos no farmacológicos que pueden ayudar a apoyar a una persona con demencia.
por la Dra. Toni Hazell, MRCGP

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Lecturas adicionales y referencias
- Formulario Nacional Británico (BNF); Servicios de Evidencia NICE (acceso solo en el Reino Unido)
- Corticosteroids - inhaled; NICE CKS, May 2020 (UK access only)
- Corticosteroids - oral; NICE CKS, enero 2024 (acceso solo en el Reino Unido)
- Clinical guideline for the prevention and treatment of osteoporosis; National Osteoporosis Guideline Group (updated September 2021)
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Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Próxima revisión: 24 Mar 2028
26 Mar 2023 | Última versión
7 Mar 2018 | Publicado originalmente
Escrito por:
Dr Colin Tidy, MRCGP

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