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testosterone

¿Son seguros los suplementos de testosterona para los hombres?

Los suplementos de testosterona pueden tener un efecto enormemente positivo en la vida de los hombres que tienen una necesidad médica. Ya sea como tratamiento para la terapia hormonal de afirmación de género de mujer a hombre o para la deficiencia de testosterona, hay numerosos beneficios para la salud mental y física. Como con cualquier medicamento, es importante estar al tanto de los posibles efectos adversos del tratamiento. También existen parámetros de seguridad cruciales para proteger contra complicaciones de salud.

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Why do men need testosterone?

Testosterone has a bad-boy reputation as the aggressive male hormone. This is only a very small part of the picture and doesn't apply to most men. What's more, this perception significantly underplays the role of this hormone in our health.

In men, testosterone is the primary sex hormone, produced in the testicles (largely under the control of hormones produced in the brain). You've probably heard that it's essential for the development of male characteristics as well as the sexual drive (libido) and function.

What you may not know is that testosterone helps the regulation of healthy bone mass, muscle mass, fat distribution, and the production of red blood cells. Its role in these functions means testosterone has an important part to play in both the mental and the physical health of transgender and cisgender men.

Testosterone supplementation for transgender (trans) men, known as testosterone hormone therapy (THT), is a gender-affirming treatment. The hormone induces physical male characteristics and suppresses female ones.

As a result, female-to-male (FTM) testosterone supplements help many trans men to feel more at home in their bodies. FTM testosterone helps to align their physical features with their internal sense of gender identity, helping to alleviate disforia de género.

This can result in a significant improvement in quality of life. It can also play an important part in mental health, for many helping to relieve related depression and anxiety problems.

Co-director of Trans Actual, Chay Brown, describes the main outcomes of THT that have made him feel more like himself:

  • Growth of body hair.

  • Redistribution of fat - less on hips and back, more on the belly.

  • Broadening out of the chest and shoulders.

  • Voice-breaking (becoming deeper).

  • An end to menstruaciones.

"However, not everyone's periods will stop on THT," he adds. "Some people also need to take oestrogen blockers.

"It's also important to understand that changes occur at different rates for everybody, which can in part be due to genetic disposition."

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Testosterone supplements can also be taken when the body is unable to produce enough testosterone - a condition known as testosterone deficiency (or hypogonadism). Low testosterone levels can have a significant impact on a man's health and quality of life.

Often, this condition develops in older men as part of the ageing process. Investigación also suggests that older men living with la obesidad and long-term diseases like diabetes y presión arterial alta are at an even greater risk.

It can occur at any age as a result of conditions affecting the testicles (sometimes called primary testosterone deficiency) or the hypothalamus or problema de la glándula pituitaria in the brain (secondary testosterone deficiency).

Testosterone deficiency has been linked to several serious conditions, including síndrome metabólico, diabetes tipo 2, y enfermedades cardiovasculares (like accidente cerebrovascular, enfermedades del corazón, y insuficiencia cardíaca).

The condition may lead to a wide range of symptoms, ranging from physical changes such as decreased body growth and muscle mass to mental changes like fatiga and concentration difficulties. It can also lead to disfunción eréctil or even infertilidad.

Treating testosterone deficiency with THT can lead to many improvements, including:

  • Higher energy levels.

  • Mental sharpness.

  • Improved sexual function and libido.

  • Masculinisation of characteristics.

If there is an underlying cause for the testosterone deficiency, THT alone is not enough and the condition will also need treating. It's important to note that the underlying cause will also affect the outlook.

There are many significant possible benefits of THT for health and your quality of life. However, as with all medications, there are certain risks and safety parameters to consider with testosterone therapy. As such, it will only be prescribed by healthcare professionals to those who have a medical need - namely for FTM gender affirmation and for those with testosterone deficiency.

Generally speaking, investigaciones finds serious adverse effects to be rare when prescribed appropriately. This said, it's important for men to be aware of the possible risks so that they can make an informed decision about testosterone therapy.

El International Medical Advisory Panel (IMAP) - risks associated with hormone therapy in order of risk level

Likely increased risk

Possible increased risk

Possible increased risk - usually only with additional risk factors

  • Diseases of the heart and blood vessels (cardiovascular disease) - there is mixed evidence relating to long-term THT, although some estudios report increased risk in older men.

  • Presión arterial alta (hypertension) - a higher risk with age and other factors such as obesity.

  • Type 2 diabetes - a higher risk with age and other factors such as obesity.

  • The destabilisation of certain psychiatric disorders - this risk is increased only in those with pre-existing disorders like trastorno and schizoaffective disorder.

No increased risk, or inconclusive evidence

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As some adverse health effects are increased with certain risk factors, your doctor will assess you for pre-existing conditions such as high blood pressure, high cholesterol, and whether you’re already at high risk for blood clots.

Your age can also increase your risk of developing serious health problems like cardiovascular disease. IMAP aconseja that pregnant trans men should not take testosterone supplements.

"Some people don't realise that it's not a case of the higher dosage, the better," advises Brown. "At a certain point, testosterone turns into oestrogen in the body. It's important to know that there are dosage limits in place not to limit effectivity, but for your safety."

The dosage of the testosterone you're taking should be the amount that gives you the optimum benefits with the least amount of relative risk. For both cis and trans men, testosterone supplements can be taken as tablets, injections, skin gels, or patches you apply to your skin.

The dosage that is safe for you to take will depend on a range of factors determined by your doctor. These factors include which supplement form you take (as recommended by the National Institute for Health and Care Excellence) and whether you are having THT for testosterone deficiency or as masculinisation therapy.

Brown also points out the importance of regular health monitoring while on testosterone supplements.

Esto incluye:

  • Red blood cell count (checking for 'thick blood').

  • Liver function.

  • Función renal.

  • Blood fat (lipid) levels - linked to having high 'bad' or low 'good’'cholesterol levels.

  • Bone mineral density - as higher doses of testosterone can lead to osteoporosis.

  • Cancer screening for breasts, cervix, uterus, and ovaries - for trans men who retain these organs.

  • Prostate cancer screening - for cis men.

Pre-treatment screenings for risks, dosage size, and monitoring are measures put in place to look after your safety and ensure you have a beneficial experience on testosterone.

Unfortunately, in the UK a number of people source testosterone supplementation from places other than their doctor. It's important to understand that medication from unauthorised providers can carry serious health risks.

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About the authorView full bio

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Amberley Davis

Escritora senior

BA (Hons), CPD

Amberley es una escritora senior en Patient y ha escrito extensamente sobre una variedad de temas de salud y bienestar.

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Dra. Sarah Jarvis

SEO Executive

MA (Cantab), BM, BCh (Oxon), DRCOG, FRCGP, MBE

After training in medicine at Cambridge and Oxford, Dr Sarah Jarvis MBE became a GP.

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