Clarithromycin for infection
Xetinin XL
Revisado por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización: 29 de mayo de 2023
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Clarithromycin is a macrolide antibiotic. It can be taken by people who are allergic to penicillin.
It is important to complete the prescribed course (unless you are told to stop). Otherwise your infection could come back.
Any side-effects are usually mild. The most common are diarrhoea, feeling sick (nausea), tummy (abdominal) discomfort, and unusual tastes.
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About clarithromycin
Tipo de medicamento | A macrolide antibiotic |
Utilizado para | Bacterial infections including chest, skin, and ear infections Some types of stomach ulcers |
También llamado | Xetinin XL® |
Disponible como | Tablets, ,modified-release tablets and oral liquid medicine |
Clarithromycin is prescribed to treat bacterial infections such as respiratory infections, ear infections and skin infections. It can be taken by adults and children. It works by stopping the bacteria causing the infection from multiplying.
Clarithromycin is also given to get rid of Helicobacter pylori. This is the bacterium believed to cause stomach ulcers. If you are prescribed it for this reason, you will also be prescribed other medicines to take alongside it.
Before taking clarithromycin
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking clarithromycin it is important that your doctor knows:
Si está embarazada o en periodo de lactancia.
Si tiene algún problema con el funcionamiento del hígado o de los riñones.
If you know you have an unusual heart rhythm.
If you have a muscle disorder called myasthenia gravis.
If you are taking any other medicines. In particular, if you are taking a 'statin' medicine for high cholesterol or colchicine for gout. This also includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.
Si alguna vez ha tenido una reacción alérgica a un medicamento.
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How to take clarithromycin
Before you start taking the antibiotic, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about clarithromycin and provide a full list of the side-effects which you may experience from taking it.
Take clarithromycin exactly as your doctor tells you to. Most forms of clarithromycin are taken twice a day, in the morning and evening. If you are given a modified-release tablet (these have an XL after the brand name, for example Xetinin XL®), you will only need to take one dose a day, as the medicine inside these tablets is released slowly over the day.
Standard-release tablets, liquid medicine, and sachets can all be taken either before or after food. Modified-release XL tablets (these are the ones that are only taken once daily) should be taken after food. Do not chew or break modified-release tablets, as this will affect the way the medicine inside them is released.
When clarithromycin is prescribed for a child, the dose will depend upon the child's weight. Make sure you read the label carefully so that you measure out the correct amount of medicine.
If you have been given clarithromycin sachets to take, open the sachet and mix the granules into a small glass of water before taking.
If you forget to take a dose, take one as soon as you remember. Try to take the correct number of doses each day, but do not take two doses at the same time to make up for a forgotten one.
It is usual for a course of treatment to last for 5-14 days. Even if you feel your infection has cleared up, keep taking the antibiotic until the course is finished (unless your doctor tells you otherwise). This is to prevent the infection from coming back and being more difficult to treat.
Aproveche al máximo su tratamiento
Some people develop thrush (redness and itchiness in the mouth or vagina) after taking a course of antibiotics. If this happens to you, speak with your doctor or pharmacist for advice about how to treat it.
Este antibiótico puede impedir que actúe la vacuna oral contra la fiebre tifoidea. Si se va a vacunar, asegúrese de que la persona que le trata sabe que está tomando este medicamento.
If you are taking a 'statin' medicine for high cholesterol your doctor may advise you to stop taking the statin whilst being treated with clarithromycin. Ask your doctor or pharmacist if you are unsure.
Taking clarithromycin does not normally affect the oral contraceptive pill. However, if you experience any diarrhoea or vomiting or any breakthrough bleeding whilst taking clarithromycin, there is a chance of contraceptive failure. Contact a pharmacist or your doctor for advice.
If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking clarithromycin.
If you buy any medicines, check with a pharmacist that they are suitable to take with this antibiotic.
If you still feel unwell after completing your course of the antibiotic, make another appointment to see your doctor.
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Can clarithromycin cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with clarithromycin. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Común clarithromycin side-effects (these affect fewer than 1 in 10 people) | ¿Qué puedo hacer si me ocurre esto? |
Feeling sick (nausea) or being sick (vomiting), stomach ache, wind (flatulence), indigestion | Stick to simple meals - avoid rich or spicy food |
Diarrea | Drink plenty of water to replace lost fluids. If the diarrhoea continues or is severe, speak with your doctor as soon as possible |
Tooth or tongue discolouration, and changes in the way things taste or smell | This will disappear after you finish your treatment |
Dolor de boca | Speak with your doctor if this becomes a problem |
Dolor de cabeza | Pida a su farmacéutico que le recomiende un analgésico adecuado |
Si experimenta cualquier otro síntoma que considere que puede deberse a este medicamento, consulte a su médico o farmacéutico.
How to store clarithromycin
Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
If you have been given liquid medicine, it will have been made up by the pharmacy and it lasts for a limited number of days only. Check the expiry date on the bottle and do not use it after this date.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
No tome nunca más de la dosis prescrita. Si sospecha que usted u otra persona ha tomado una sobredosis de este medicamento, acuda al servicio de urgencias de su hospital. Llévese el envase, aunque esté vacío.
Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.
Si va a someterse a una operación o a un tratamiento dental, comunique a la persona que lleve a cabo el tratamiento qué medicamentos está tomando.
No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.
Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.
Informar de los efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede notificarlos en línea a través del sitio web de la Tarjeta Amarilla.
Lecturas complementarias y referencias
- Manufacturer's PIL, Clarithromycin 250 mg & 500 mg Tablets; Aurobindo Pharma - Milpharm Ltd, The electronic Medicines Compendium. Dated July 2021.
- Medicamentos BNF completa 89ª edición; Asociación Médica Británica y Real Sociedad Farmacéutica de Gran Bretaña, Londres.
Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
Fecha de la próxima revisión: 28 de mayo de 2026
29 de mayo de 2023 | Última versión

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