Posaconazol para las infecciones fúngicas
Noxafil
Revisado por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 19 Jul 2023
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Posaconazole treats fungal infections within your body.
If you have been supplied with tablets, you can take your doses before or after meals. If you have been supplied with liquid medicine, try to take each dose with a snack or straight after a meal.
If you start being sick (vomiting) or develop diarrhoea, let your doctor know.
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About posaconazole
Tipo de medicamento | Antifúngico |
Utilizado para | Infecciones fúngicas |
También llamado | Noxafil® |
Disponible como | Comprimidos y medicamentos orales líquidos |
Fungal infections within the body sometimes occur. You are more at risk of developing an internal fungal infection if your immune system does not work properly. For example, if you are taking chemotherapy, or if your immune system is being suppressed following an organ or cell transplant. Internal fungal infections can be serious and, sometimes, life-threatening.
Posaconazole is used to treat (or prevent) serious fungal infections, particularly when other antifungal medicines have not been effective or are not suitable. It works by stopping the growth of the fungi causing the infection.
Before taking posaconazole
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking posaconazole it is important that your doctor knows:
Si está embarazada o en periodo de lactancia.
If you have liver problems.
If you have any heart or heart rhythm problems.
Si padece porfiria, un raro trastorno sanguíneo hereditario.
Si alguna vez ha tenido una reacción alérgica a un medicamento.
If you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines. This is because a number of medicines can interfere with the way posaconazole works.
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How to take posaconazole
Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. It will give you more information about posaconazole and will provide you with a full list of side-effects which you may experience from taking it.
Take posaconazole exactly as your doctor tells you to. How frequently you will need to take it will depend upon why you are taking it, but as a guide, it will range from once a day to four times daily if you are taking liquid medicine. If you are taking tablets, it is likely you will be prescribed 300 mg (three tablets) to take twice daily on the first day, and then 300 mg (three tablets) to take once a day on the following days.
The tablets can be taken either before or after meals. Swallow the tablets with a drink of water. Do not crush or break the tablets - they should be swallowed whole.
The liquid medicine should be taken during, or straight after, a meal or snack where possible as this will help your body to absorb the medicine. If you are unable to eat much, make sure your doctor knows this, as you may be better taking smaller doses more frequently. Use the spoon included in your pack to measure out your doses. It is marked for doses of 2.5 ml and 5 ml.
Space your doses evenly throughout the day, and keep taking this medicine until your course is finished unless you are told otherwise. This is to make sure there is no chance of further infection.
If you forget to take a dose, take it as soon as you remember. However, if when you remember, it is nearly time for your next dose, leave out the forgotten dose. Do not take two doses together to make up for a missed dose.
Aproveche al máximo su tratamiento
Remember to keep your regular appointments with your doctor. This is so your doctor can check on your progress. Your doctor will want to do some blood tests during this treatment, to check that your liver is working properly.
If you buy any medicines, check with a pharmacist that they are suitable to take with posaconazole. This is because several medicines interfere with it and may either decrease how well it works or increase the risk you may experience side-effects.
You must not get pregnant while you are taking posaconazole. Make sure you have discussed with your doctor which types of contraception are suitable for you and your partner if this is relevant for you.
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Can posaconazole cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with posaconazole. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common posaconazole side-effects (these affect around 1 in 10 people) | ¿Qué puedo hacer si me ocurre esto? |
Sentirse mal (náuseas) o estar enfermo (vómitos) | If this is severe, let your doctor know straightaway |
Diarrea | Drink plenty of water to replace lost fluids. If it continues or is severe, let your doctor know straightaway |
Tummy (abdominal) pain, indigestion, lack of appetite | Stick to simple foods - avoid spicy meals |
Sensación de sueño o mareo | Rest whenever you can. Do not use tools or machines, and do not drive |
Boca seca | Prueba a mascar chicle sin azúcar o chupar caramelos sin azúcar |
Headache, itchy rash, tingling feelings, high temperature (fever), infection | Si alguno de estos síntomas le resulta molesto, comuníqueselo a su médico |
Feeling confused or weak (due to abnormal levels of electrolytes in your blood) | Your doctor will be monitoring your blood for this |
Si experimenta cualquier otro síntoma que crea que puede deberse al medicamento, hable con su médico o farmacéutico.
How to store posaconazole
Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
The liquid medicine keeps for four weeks once the bottle has been opened. Do not use it after this time.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
No tome nunca más de la dosis prescrita. Si sospecha que usted u otra persona ha tomado una sobredosis de este medicamento, acuda inmediatamente al servicio de urgencias de su hospital. Llévese el envase, aunque esté vacío.
Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.
No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.
Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.
Informar de los efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede notificarlos en línea a través del sitio web de la Tarjeta Amarilla.
Lecturas complementarias y referencias
- Manufacturer's PIL, Noxafil® 40 mg/ml oral suspension; Merck Sharp & Dohme Limited, The electronic Medicines Compendium. Dated June 2023.
- Manufacturer's PIL, Noxafil® 100 mg Gastro-resistant Tablets; Merck Sharp & Dohme Limited, The electronic Medicines Compendium. Dated June 2023.
- Medicamentos BNF completa 89ª edición; Asociación Médica Británica y Real Sociedad Farmacéutica de Gran Bretaña, Londres.
Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
Fecha prevista para la próxima revisión: 18 jul 2026
19 Jul 2023 | Última versión

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