Ir al contenido principal

Linezolid for infection

Zyvox

Linezolid is an antibiotic which is given for serious infections. It will be prescribed by a specialist doctor.

The dose is 600 mg every 12 hours. This will be as an injection, or as a tablet or liquid medicine.

While you are taking linezolid, try to avoid eating mature cheese, yeast extracts (eg, Marmite®, Bovril®) or soya bean products such as soy sauce. These foods interact with linezolid and cause unpleasant symptoms.

At a glance

  • Linezolid is an antibiotic used for serious infections that are hard to treat.

  • It treats pneumonia and skin infections caused by MRSA bacteria.

  • You must tell your doctor about all other medicines you are taking.

  • Take doses 12 hours apart, usually morning and evening.

  • Avoid foods high in tyramine, such as mature cheese, and alcohol while taking this medicine.

  • You will need weekly blood tests during treatment.

  • See your doctor immediately if you have vision changes or a throbbing headache after eating.

Continúa leyendo abajo

About linezolid

Tipo de medicamento

An oxazolidinone antibiotic

Usado para

Treatment of pneumonia; difficult-to-treat skin infections

También llamado

Zyvox®

Disponible como

Tablets, oral liquid medicine, and injection

Linezolid is an antibiotic which is used for serious infections which are difficult to treat with other antibiotics.

It is used to treat neumonía, which is a serious lung infection. It is also used to treat skin and soft tissue infections caused by infection with MRSA bacteria. These types of bacteria are resistant to treatment with many other antibiotics. Treatment is started in hospital, often as an injection given directly into a vein. As your treatment progresses, you may be given tablets or liquid medicine to take instead of having injections.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start linezolid it is important that your doctor knows:

  • If you are taking any other medicines. It is muy important that you tell your doctor about todos the medicines that have been prescribed for you, as well as any medicines that you have bought without a prescription or herbal and complementary medicines. This is because linezolid must not be taken at the same time as some other medicines. These include some medicines for depression, 'triptans' for migraine, some painkillers, and decongestant medicines which are often included in cold and flu remedies.

  • Si estás embarazada o amamantando.

  • If you have any problems with the way your liver works, or the way your kidneys work.

  • If you have high blood pressure (hypertension).

  • Si tienes una glándula tiroides hiperactiva.

  • If you have ever had a fit (seizure).

  • If you have schizophrenia or bipolar depression.

  • If you have been told you have a carcinoid tumour (a rare tumour of the hormone system), or a tumour on your adrenal glands, called phaeochromocytoma.

  • Si alguna vez has tenido una reacción alérgica a un medicamento.

Continúa leyendo abajo

  • Ask to read the manufacturer's printed information leaflet. It will give you more information about linezolid and will provide a full list of the side-effects which you may experience from taking it. Your doctor may also give you some additional printed information - it is important that you read all the information you are given.

  • Take linezolid exactly as your doctor tells you to. You will be asked to take two doses each day, 12 hours apart. This will usually mean taking a dose each morning and evening. You can take linezolid before or after meals.

  • If you have been given the oral liquid medicine, do not shake the bottle. Instead, turn the bottle upside down a few times before you remove the lid and pour out your dose.

  • Try to remember to take your doses at the correct times, and not to miss any. If you do forget to take a dose, take it as soon as you remember and then take the next dose 12 hours afterwards. Continue to take a dose every 12 hours. Do not take two doses together to make up for a forgotten dose.

  • It is usual for a course of treatment to last for 10-14 days. Even if you feel your infection has cleared up, keep taking the antibiotic until the course has finished (unless your doctor tells you otherwise). This is to prevent the infection from coming back and being more difficult to treat.

  • Linezolid can react with a substance called tyramine which is contained in foods such as mature cheese, yeast extracts (eg, Marmite®, Bovril®), and soya bean products (eg, soy sauce). While you are taking linezolid, avoid eating any of these, as they will cause an increase in your blood pressure. Also, avoid drinking alcohol, especially draught beers.

  • Keep the scheduled appointments with your doctor so that your progress can be monitored. You will need to have a blood test each week while you are taking this antibiotic.

  • Some people develop thrush (redness and itchiness in the mouth or vagina) after taking a course of antibiotics. If this happens to you, speak with your doctor or pharmacist for advice.

  • Do not buy or take any medicines without checking first with your doctor or a pharmacist that they are suitable for you to take with this antibiotic.

  • If you are due to have any other medical treatment, tell the person carrying out the treatment that you are taking this antibiotic.

  • This antibiotic can stop the oral typhoid vaccine from working. If you are due to have any vaccinations, make sure the person treating you knows that you are taking this medicine.

Continúa leyendo abajo

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with linezolid. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Común

linezolid side-effects (these affect fewer than 1 in 10 people)


¿Qué puedo hacer si experimento esto?

Dolor de cabeza

If the headache is severe and occurs after eating food, speak with your doctor straightaway

Diarrea

Drink plenty of water to replace lost fluids. If the diarrhoea is severe, speak with your doctor straightaway

Sentirse mal (náuseas) o estar enfermo (vómitos)

Mantente con comidas simples - evita alimentos ricos o picantes

Metallic taste in the mouth

Try taking your doses with some food or a drink to take away the taste

Cambios en algunos análisis de sangre

Your doctor will ask you to have regular blood tests to check for this

Importante: your doctor will discuss with you the possibility of some less common side-effects occurring. You must let your doctor know straightaway about the following:

  • Any changes in your eyesight, such as blurred vision or colour changes.

  • If you develop a throbbing headache after eating or drinking something.

If you experience any other symptoms which you think may be due to the medicine, speak with your doctor or pharmacist for advice.

  • Mantenga todos los medicamentos fuera del alcance y la vista de los niños.

  • Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.

  • Si te han dado medicina líquida, habrá sido preparada por la farmacia y solo dura un número limitado de días. Verifica la fecha de caducidad en el frasco y no la uses después de esta fecha.

Información importante sobre todos los medicamentos

Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.

Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.

Si vas a someterte a una operación o a un tratamiento dental, informa a la persona que realiza el tratamiento sobre los medicamentos que estás tomando.

No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.

Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.

MHRA - Reporte de reacciones adversas

Informe los efectos secundarios sospechosos de medicamentos, vacunas, cigarrillos electrónicos, incidentes con dispositivos médicos, productos defectuosos o falsificados (falsos) a la Agencia Reguladora de Medicamentos y Productos Sanitarios para garantizar un uso seguro y efectivo.

verificador de síntomas

¿Inseguro sobre mezclar medicamentos?

Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.

Preguntas frecuentes

What kind of infections is Linezolid typically prescribed for?

Linezolid is an antibiotic used for serious infections that are hard to treat with other antibiotics. Specifically, it's used for pneumonia, which is a serious lung infection, and skin and soft tissue infections caused by MRSA bacteria. MRSA is known for being resistant to many other antibiotic treatments.

Is it normal to start Linezolid treatment in hospital?

Yes, treatment with linezolid often begins in a hospital setting. It is commonly given as an injection directly into a vein. As your treatment progresses, you may transition to taking it as tablets or a liquid medicine.

How long will I usually need to take Linezolid?

A typical course of linezolid treatment usually lasts between 10 to 14 days. It's important to complete the entire course of antibiotics, even if you start feeling better, unless your doctor advises you otherwise. This helps prevent the infection from returning and becoming harder to treat.

What foods or drinks should I avoid while taking Linezolid?

You should avoid foods containing tyramine, such as mature cheese, yeast extracts (like Marmite® or Bovril®), and soya bean products (like soy sauce). Eating these can increase your blood pressure while on linezolid. It's also advised to avoid drinking alcohol, especially draught beers.

Why do I need weekly blood tests while on Linezolid?

Regular blood tests are necessary each week while you are taking linezolid. This is because linezolid can cause changes to some blood test results, and your doctor will monitor these to ensure your safety and the effectiveness of the treatment.

What should I do if I notice changes to my eyesight while taking Linezolid?

It is important to tell your doctor straightaway if you experience any changes in your eyesight, such as blurred vision or changes in colour perception. These are less common but important side-effects that need immediate medical attention.

Can Linezolid affect other medications I'm taking, including over-the-counter or herbal remedies?

Yes, it's crucial to inform your doctor about all medicines you are taking, including prescribed ones, those bought without a prescription, and any herbal or complementary medicines. Linezolid must not be taken with certain other medications, such as some antidepressants, 'triptans' for migraine, specific painkillers, and decongestants found in cold and flu remedies.

Lecturas adicionales y referencias

Continúa leyendo abajo

About the authorView full bio

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Historial del artículo

La información en esta página está escrita y revisada por pares por clínicos calificados.

  • Next review due: 28 Nov 2027
  • 29 de mayo de 2023 | Última versión

    Última actualización por

    Michael Stewart, MRPharmS

    Revisado por pares por

    Sid Dajani
verificador de elegibilidad para la gripe

Pregunta, comparte, conecta.

Navega por discusiones, haz preguntas y comparte experiencias en cientos de temas de salud.

Suscríbete al boletín de Patient

Tu dosis semanal de consejos de salud claros y confiables, escritos para ayudarte a sentirte informado, seguro y en control.

Por favor, introduce una dirección de correo electrónico válida

By subscribing you accept our Política de Privacidad. Puedes darte de baja en cualquier momento. Nunca vendemos tus datos.