Depersonalisation
Revisado por pares por Dr Krishna Vakharia, MRCGPAuthored by Dr Colin Tidy, MRCGPPublicado originalmente 27 Jul 2023
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It's not uncommon to have a feeling of depersonalisation (not feeling like yourself) for short periods, such as when you feel very stressed, but sometimes the problem can last for a long time and cause a lot of difficulty and distress.
At a glance
Depersonalisation makes you feel unreal, detached from your body, or like an outside observer of yourself.
Derealisation makes you experience other people, objects, or the world as strange or unreal.
Temporary feelings can arise from stress, exhaustion, illness, or recreational drugs.
Persistent symptoms can lead to a diagnosis of depersonalisation-derealisation disorder.
Risk factors include trauma, severe stress, anxiety, depression, and some drug use.
Treatment often involves psychotherapy and lifestyle changes.
There is no specific medicine for depersonalisation, but some antidepressants may help.
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What is depersonalisation?
Depersonalisation means that you don’t feel like yourself anymore, feeling yourself as strange or unreal, or feeling empty and detached from reality. It might seem as though your mind and body are operating separately from one another.
Depersonalisation may take the form of emotional and/or physical numbing, a sense of watching yourself from a distance or ‘being in a play’, or changes in how you sense things, such as a distorted sense of time.
The difference between depersonalisation and derealisation
Derealisation is slightly different to depersonalisation. Derealisation means experiencing other people, objects, or the world as strange or unreal (eg, dreamlike, distant, foggy, lifeless, colourless, or visually distorted).
Depersonalisation and derealisation can be very unsettling and explaining the experience to others can be very difficult, with a fear of being thought of as ‘mad’ when trying to describe the sense of disconnection and hazy thinking. It can be easy to be convinced that you're losing touch with reality completely.
Temporary feelings of depersonalisation or derealisation can occur when you are under stress, during extreme emotional states or exhaustion, when physically ill, or under the influence of recreational drugs. it's only when these experiences are persistent or keep happening that the diagnosis of depersonalisation-derealisation disorder is used. Episodes of symptoms in depersonalisation-derealisation disorder may be associated with adverse life events or conflicts with others.
Symptoms of depersonalisation
Volver al contenidoThe onset of Depersonalisation-Derealisation Disorder can occur in childhood but more often it starts in the mid-teenage years, with an average age at onset of about 16 years of age. Developing symptoms for the first time after 25 years of age is very rare.
The onset of depersonalisation-derealisation disorder can vary from sudden to gradual, with initial episodes of limited severity and frequency, gradually replaced by symptoms that are more severe and persistent.
Episodes of depersonalisation-derealisation disorder can vary in duration, ranging from brief (hours or days) to prolonged (weeks, months or years). Factors such as emotional stress, anxiety, lack of sleep or recreational drug use can make symptoms much worse. The problem is usually long lasting (chronic) and persistent.
The symptoms of depersonalisation may include:
Feeling unreal and that you're an outside observer of your thoughts, feelings and your body, as if you were floating in air above yourself.
Feeling like a robot or that you're not in control of your speech or movements.
The sense that your body, legs or arms appear distorted, enlarged or shrunken, or that your head is wrapped in cotton wool.
Unable to feel emotion and a numbness of your senses or responses to the world around you.
A sense that your memories lack emotion, and that they may or may not be your own memories.
A common associated symptom in depersonalisation-derealisation disorder is an altered sense of time, such as a feeling of time slowing down or speeding up. There may also be frequent fears of ‘going crazy’, as well as a loss of the sense of ‘ownership’ of some of your personal memories, or reduced emotional responses.
Depersonalisation-derealisation disorder often occurs with other mental health disorders including depresión, anxiety disorder, ataques de pánico, obsessive compulsive disorder (OCD), or phobias, or with a personality disorder.
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Causes of depersonalisation
Volver al contenidoWhile there is no known single, identifiable cause for depersonalisation, there are some common risk factors associated with it:
Trauma.
Severe stress.
Depresión.
Ansiedad.
Panic disorder.
Emotional maltreatment in childhood.
Marijuana (cannabis) use.
Hallucinogenic or psychedelic use.
Recreational drug use, especially of marijuana or hallucinogens, is a common trigger for depersonalisation and derealisation symptoms. However, depersonalisation-derealisation disorder can only be diagnosed if the symptoms persist beyond the period of intoxication or withdrawal from these substances.
Therefore, depersonalisation can be caused by a range of different factors and each person will have different circumstances leading to their symptoms.
Diagnosing depersonalisation
Volver al contenidoThe diagnosis of depersonalisation-derealisation disorder can also only apply if the symptoms cannot be explained by any other mental health or other problem, or any effect of recreational drugs or medications.
For the diagnosis to be made, the symptoms of depersonalisation-derealisation disorder should result in significant distress or problems with personal, family or social life, and with education or work. If it is possible to function normally, it is only through a great deal of additional effort.
A mental healthcare professional (such as a psychologist or psychiatrist) will make an assessment of your symptoms to see whether they are consistent with the diagnosis. The assessment will include a very thorough history of your symptoms and an assessment of the possible underlying causes of your symptoms.
The assessment for the diagnosis of depersonalisation will also be used to gain understanding of the circumstances leading up to your symptoms, in order to identify potential triggers. In this way, specific ways to target the underlying problems that are driving your symptoms can be considered.
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Treatment for depersonalisation
Volver al contenidoThe way you experience depersonalisation and derealisation is specific and unique to you, which is why a personalised approach is most effective in treating depersonalisation. The different treatments can be used in combination.
Cambios en el estilo de vida
Getting enough sunlight exposure.
Terapia psicológica
Psychotherapy can be very effective for treating depersonalisation, even if you have severe symptoms. Like all treatments, psychotherapy needs to be adapted to the specific needs of each individual person.
Sometimes the type of psychotherapy needs to be changed between being supportive when symptoms are particularly difficult to deal with, and then more dynamic when symptoms are much less severe.
Therefore, during times of severe difficulty with depersonalisation symptoms or severe depression and anxiety, supportive interventions (crisis interventions and reinforcing coping skills and strategies) are usually the most appropriate.
During periods of relatively mild symptoms a more dynamic (psychodynamic) approach, such as terapia cognitivo-conductual (TCC), may be used, focusing on self-reflection and self-evaluation, to explore effective coping strategies and relationship patterns.
Medicamento
There is no recognised medicine to help treat depersonalisation. However, there is some evidence to support the use of selective serotonin reuptake inhibitor (SSRI) antidepressants, and more recently the combination of a medicine called lamotrigina with an SSRI has shown some benefit.
¿Cuál es el resultado?
Volver al contenidoThe outcome for derealisation and depersonalisation is often good. A large number of people get better with time and others respond well to treatments, particularly to psychotherapy.
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Preguntas frecuentes
Can depersonalisation ever be a normal experience?
Yes, temporary feelings of depersonalisation or derealisation can occur if you are under stress, experiencing extreme emotional states or exhaustion, when you are physically unwell, or if you've used recreational drugs. It's only considered a disorder if these experiences are persistent or happen repeatedly.
At what age does Depersonalisation-Derealisation Disorder typically begin?
While it can start in childhood, it most often begins in the mid-teenage years, with the average age of onset being around 16. It's very uncommon for symptoms to develop for the first time after the age of 25.
How long do episodes of depersonalisation last?
The duration of episodes can vary greatly. They can be brief, lasting only hours or days, or they can be prolonged, continuing for weeks, months, or even years. Factors like emotional stress, anxiety, lack of sleep, or recreational drug use can make the symptoms worse.
Can using recreational drugs permanently cause depersonalisation?
Recreational drug use, especially marijuana or hallucinogens, is a common trigger for these symptoms. However, a diagnosis of Depersonalisation-Derealisation Disorder is only made if the symptoms continue even after the period of intoxication or withdrawal from these substances has passed.
How do doctors determine if my depersonalisation is part of the disorder or something else?
A mental healthcare professional will conduct a thorough assessment, including your symptom history and potential underlying causes. This assessment helps them understand the circumstances leading to your symptoms and rule out other mental health problems, medical conditions, or the effects of recreational drugs or medications, before diagnosing Depersonalisation-Derealisation Disorder.
What kind of lifestyle changes can help with depersonalisation?
Lifestyle changes that can help include improving your sleep patterns, getting enough sunlight, exercising regularly, maintaining a healthy diet, and finding ways to relax and reduce stress.
Is there any medication that specifically treats depersonalisation?
There is currently no single medicine recognised to treat depersonalisation specifically. However, there is some evidence that SSRI antidepressants may be helpful, and more recently, combining an SSRI with a medicine called lamotrigine has shown some benefit.
Lecturas adicionales y referencias
- Clasificación Internacional de Enfermedades 11ª Revisión; Organización Mundial de la Salud, 2019/2021
- Somer E, Amos-Williams T, Stein DJ; Evidence-based treatment for Depersonalisation-derealisation Disorder (DPRD). BMC Psychol. 2013 Oct 28;1(1):20. doi: 10.1186/2050-7283-1-20. eCollection 2013.
- Mishra S, Das N, Mohapatra D, et al; Mindfulness-Based Cognitive Therapy in Depersonalization-Derealization disorder: A Case Report. Indian J Psychol Med. 2022 Nov;44(6):620-621. doi: 10.1177/02537176211040259. Epub 2021 Sep 28.
- Gentile JP, Snyder M, Marie Gillig P; STRESS AND TRAUMA: Psychotherapy and Pharmacotherapy for Depersonalization/Derealization Disorder. Innov Clin Neurosci. 2014 Jul;11(7-8):37-41.
About the authorView full bio

Dr Colin Tidy, MRCGP
Médico General, Autor Médico
MBBS, MRCGP, MRCP (Paediatrics), DCH
Dr Colin Tidy is an NHS Doctor, based in Oxfordshire.
About the reviewerView full bio

Dr Krishna Vakharia, MRCGP
Chief Medical Officer for Health, Optum UK
MBChB, MRCGP(2013), BMedSci (hons), DFSRH, DRCOG, PGDipDerm (Distn)
La Dra. Krishna Vakharia es una médica general del NHS. También es examinadora habitual del Diploma de Posgrado en Dermatología Práctica en la Universidad de Cardiff, además de ser la Directora Médica de salud en Optum UK.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Próxima revisión: 25 Jul 2028
27 Jul 2023 | Publicado originalmente
Escrito por:
Dr Colin Tidy, MRCGPRevisado por pares por
Dr Krishna Vakharia, MRCGP

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