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Lamotrigine for epilepsy

Lamictal

Lamotrigine is prescribed to treat two different conditions - epilepsy and bipolar disorder.

Take your doses regularly. Do not stop taking lamotrigine unless your doctor tells you to.

You can take your doses either before or after food.

At a glance

  • Lamotrigine is an antiepileptic medicine used for epilepsy and bipolar disorder.

  • It comes as tablets and dispersible tablets, usually taken once or twice daily.

  • Your doctor will start you on a low dose, gradually increasing it.

  • Take your doses at the same time each day, with or without food.

  • Do not stop taking lamotrigine suddenly, as this can cause problems.

  • Contact your doctor if you develop a severe skin rash, high temperature, or unexplained bruising.

  • If you have suicidal thoughts or mood changes, tell your doctor straightaway.

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About lamotrigine

Tipo de medicamento

Un medicamento antiepiléptico

Usado para

Epilepsy; bipolar disorder

También llamado

Lamictal®

Disponible como

Tablets and dispersible tablets

Having epilepsy means that you have had more than one unexplained fit, or seizure. A seizure is a short episode of symptoms caused by a burst of abnormal electrical activity in your brain. Different parts of the brain control different functions of your body, so the symptoms that occur during a seizure will depend on where the abnormal burst of electrical activity occurs. Symptoms that may occur during a seizure can affect your muscles, sensations, behaviour, emotions, and consciousness, or a combination of these. The seizures can be prevented in most people by suitable antiepileptic medication. Lamotrigine is a commonly used medicine. It works by stabilising the electrical activity of your brain, which helps to prevent the seizures from occurring.

Lamotrigine is also prescribed as a treatment for bipolar disorder, which is a condition where there can be extreme mood swings. It is helpful in preventing the periods of depression that occur in people with this disorder.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking lamotrigine it is important that your doctor knows:

  • Si estás embarazada, intentando tener un bebé o amamantando.

  • Si tienes algún problema con el funcionamiento de tus riñones o con el funcionamiento de tu hígado.

  • If you have enfermedad de Parkinson.

  • If you have any problems with the way your heart works.

  • Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.

  • Si alguna vez has tenido una reacción alérgica a un medicamento.

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  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about lamotrigine and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take lamotrigine exactly as your doctor tells you to. Your dose will be printed on the label of the pack to remind you about what the doctor said. It is usual to start treatment on a low dose, and then for the dose to be increased gradually to a regular maintenance dose. It is usual to take either one or two doses every day. Doses for children are tailored to their age and weight.

  • Try to take your doses at the same times of day, each day. Having a routine will help you to remember to take your doses regularly. You can take lamotrigine either before or after meals.

  • Swallow the tablet whole with a drink of water, do not crush or chew the tablet.

  • If you have been supplied with lamotrigine dispersible/chewable tablets, you can stir the tablet into a little water to help you swallow, or you can chew the tablet before swallowing it. Always use whole tablets for your dose, do not try to split the tablets.

  • Si olvida tomar una dosis, tómela tan pronto como lo recuerde, a menos que esté cerca la hora de su próxima dosis, en cuyo caso omita la dosis olvidada. No tome dos dosis juntas para compensar una dosis olvidada.

  • Cuando comienzas un nuevo tratamiento para la epilepsia, puede haber un cambio en el número o tipo de convulsiones que experimentas. Tu médico te aconsejará al respecto.

  • Intenta mantener tus citas regulares con tu médico. Esto es para que tu médico pueda verificar tu progreso.

  • Different formulations and makes of lamotrigine can act in a slightly different way in your body. Because of this, your doctor may recommend that you continue to take lamotrigine from the same manufacturer each time you obtain a new supply. If so, each time you collect a prescription, check to make sure your supply looks the same and that the name is the same. If you are unsure, or if you have any questions about your prescription, please ask your pharmacist to advise you.

  • If you buy any medicines, check with a pharmacist that they are suitable for you to take.

  • While you are being treated for epilepsy there is a small risk that you may develop mood changes, distressing thoughts and feelings about suicide. If this happens, you must tell your doctor about it straightaway.

  • People with epilepsy must stop driving at first. Your doctor will advise you about when it may be possible for you to start driving again. This will usually be after a year free of seizures.

  • Antiepileptic medicines can harm an unborn child. If you are a woman, make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. If you want to have a family, discuss this with your doctor so that you can be given advice from a specialist antes you become pregnant.

  • You need to take lamotrigine regularly every day. Do not stop taking it unless your doctor tells you to stop. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually if this becomes necessary.

  • If you drink alcohol, ask your doctor for advice. Your doctor may advise you not to drink alcohol while you are on this medicine.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with lamotrigine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common lamotrigine side-effects

(estos afectan a más de 1 de cada 10 personas)

¿Qué puedo hacer si experimento esto?

Erupción cutánea

You should let your doctor know about this as soon as possible

Dolor de cabeza

Bebe mucha agua y pide a tu farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza continúan, informa a tu médico

Common lamotrigine side-effects (these affect fewer than 1 in 10 people)


¿Qué puedo hacer si experimento esto?

Back or joint aches and pains

Pídale a su farmacéutico que le recomiende un analgésico adecuado

Sentirse mal (náuseas) o estar enfermo (vómitos), diarrea

Stick to simple meals - avoid rich and spicy food. Drink plenty of water

Sintiéndose mareado, cansado o somnoliento

No conduzca y no utilice herramientas o máquinas

Boca seca

Intenta masticar chicle sin azúcar o chupar caramelos sin azúcar

Feeling agitated or irritable, difficulties sleeping, feeling unsteady or shaky

Si alguno de estos se vuelve problemático, hable con su médico para obtener consejo

Importante: your doctor will discuss with you the possibility that lamotrigine can cause blood disorders and allergic skin reactions. Although these occur much less commonly than the side-effects listed above, it is important that you contact your doctor de inmediato if you experience any of the following symptoms:

  • A high temperature (fever) or swollen glands.

  • Extreme tiredness.

  • Unexplained bruising or bleeding.

  • Una erupción cutánea severa.

If you experience any other symptoms which you think may be due to lamotrigine, speak with your doctor or pharmacist for further advice.

  • Mantenga todos los medicamentos fuera del alcance y la vista de los niños.

  • Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.

Información importante sobre todos los medicamentos

Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.

Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.

Si vas a someterte a una operación o tratamiento dental, informa a la persona que realiza el tratamiento sobre los medicamentos que estás tomando.

No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.

Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.

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Preguntas frecuentes

How does lamotrigine work in the brain to prevent seizures?

Lamotrigine works by stabilising the electrical activity in your brain. This helps to prevent seizures from occurring by controlling the abnormal bursts of electrical activity that cause them.

Can I switch between different brands of lamotrigine?

Different formulations and brands of lamotrigine can act slightly differently in your body. Your doctor might recommend that you stick with the same manufacturer each time you get a new supply. If you're getting a prescription, always check that the supply looks the same and the name is consistent. If you have any concerns, ask your pharmacist.

What should I do if I get a skin rash while taking lamotrigine?

A skin rash is a very common side-effect of lamotrigine. You should inform your doctor about it as soon as possible. While many side-effects improve as your body adjusts to the medicine, it's important to get a skin rash checked.

I feel dizzy and tired since starting lamotrigine. Is this normal?

Feeling dizzy, tired, or sleepy is a common side-effect, affecting fewer than 1 in 10 people. If you experience these symptoms, you should avoid driving and operating tools or machines. If these effects become troublesome, you should speak with your doctor for advice.

What should I do if I forget to take a dose of lamotrigine?

If you forget a dose, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose. Never take two doses together to make up for a forgotten dose.

Can lamotrigine affect me if I'm planning to have an operation or dental treatment?

Yes, it's important to inform the person carrying out any operation or dental treatment that you are taking lamotrigine. They need to be aware of all the medicines you are taking.

Can I stop taking lamotrigine once my seizures are under control?

You need to take lamotrigine regularly every day and should not stop taking it unless your doctor tells you to do so. Stopping treatment suddenly can lead to problems, and your doctor will likely advise you to reduce your dose gradually if it becomes necessary to stop.

Lecturas adicionales y referencias

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Historial del artículo

La información en esta página está escrita y revisada por pares por clínicos calificados.

  • Next review due: 1 Jan 2027
  • 2 Jan 2024 | Última versión

    Última actualización por

    Michael Stewart, MRPharmS

    Revisado por pares por

    Sid Dajani
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