Indometacina para el dolor y la inflamación
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Revisado por pares por Dr Colin Tidy, MRCGPÚltima actualización por Michael Stewart, MRPharmSLast updated 19 Jun 2023
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Indometacin is a medicine called a non-steroidal anti-inflammatory drug. It is also known as 'an NSAID'.
The most common side effects are indigestion, heartburn, stomach pain and feeling sick or vomiting.
Some people can also feel dizzy while taking indometacin - this may affect your ability to use tools or machines and to drive.
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About indometacin
Tipo de medicamento | Medicamento antiinflamatorio no esteroideo (AINE) |
Usado para | Alivio del dolor y la inflamación |
También llamado | Indomethacin (in US; Indocin® Indocid® |
Disponible como | Capsules, modified-release capsules and suppositories, oral liquid medicine (in US) |
What is indometacin used for?
Volver al contenidoIndometacin a type of anti-inflammatory medicine used to treat painful conditions such as artritis, esguinces y distensiones, dolor de espalda, dolor menstrual, y gout pain.
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How does indometacin work?
Volver al contenidoIndometacin works by blocking the effect of chemicals in your body, called cyclo-oxygenase (COX) enzymes. These enzymes help to make other chemicals in the body, called prostaglandins.
Some prostaglandins are produced at sites of injury or damage, and cause pain and inflammation. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which means pain and inflammation are eased.
Side effects of indometacin
Volver al contenidoCommon side effects of indometacin are:
Indigestión.
heartburn.
Dolor estomacal.
Feeling sick or vomiting.
Diarrea o estreñimiento.
Sentirse mareado.
You will find a full list in the manufacturer's information leaflet supplied with your medicine.
Los efectos no deseados a menudo mejoran a medida que su cuerpo se adapta al nuevo medicamento, pero hable con su médico o farmacéutico si alguno de los siguientes persiste o se vuelve problemático.
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How to manage indometacin side effects
Volver al contenidoCommon indometacin side effects | ¿Qué puedo hacer si experimento esto? |
Indigestión, acidez (reflujo), dolor de estómago | Make sure you take your doses after a meal. If the discomfort continues, speak with your doctor |
Sentirse mal (náuseas) o estar enfermo (vómitos) | Mantente con comidas simples - evita alimentos ricos o picantes |
Diarrhoea or constipation | Bebe mucha agua |
Sensación de mareo | Do not drive and do not use tools or machines when dizzy |
Importante: if you experience any of the following symptoms, stop taking indometacin and contact your doctor for advice straightaway:
Si tienes alguna dificultad para respirar, como sibilancias o falta de aliento.
Si tienes algún signo de una reacción alérgica, como hinchazón alrededor de la boca o la cara, o una erupción cutánea severamente pruriginosa.
If you pass blood or black stools, vomit blood, or have severe tummy (abdominal) pains.
Si experimenta otros síntomas que cree que pueden deberse al medicamento, hable con su médico o farmacéutico para obtener más consejos.
Who should not take indometacin?
Volver al contenidoSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking indometacin, it is important that your doctor knows:
Si tienes asma u otro trastorno alérgico.
If you have ever had a stomach or duodenal ulcer, or if you have an inflammatory bowel disorder such as enfermedad de Crohn o colitis ulcerosa.
Si estás embarazada o amamantando.
If you are over 65 years of age.
Si tienes problemas de hígado o riñón.
Si tienes una afección cardíaca, o un problema con tus vasos sanguíneos o circulación.
If you have presión arterial alta.
If you have a high blood sugar level or cholesterol level.
Si eres fumador.
If you have epilepsy, enfermedad de Parkinson, or a mental health problem.
If you have any blood clotting problems.
If you have a connective tissue disorder, such as systemic lupus erythematosus. This condition is also called lupus, or SLE.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, como medicamentos herbales y complementarios.
If you have ever had an allergic reaction to any other NSAID (such as aspirina, naproxeno, diclofenaco, y ibuprofeno), o a cualquier otro medicamento.
How to take indometacin
Volver al contenidoBefore starting indometacin, read the patient information leaflet inside the pack. It explains the strength of your capsules and lists possible side effects.
Take indometacin exactly as your doctor has advised. Your dose and how often to take it will be shown on the label. Ask your pharmacist if you are unsure.
Take the capsules with food or after a snack to reduce the risk of indigestion. Swallow them with a drink if needed.
If you forget a dose, take it as soon as you remember unless it is nearly time for the next one. Do not take two doses at the same time.
Obteniendo el máximo de tu tratamiento
Volver al contenidoYour doctor will prescribe the lowest effective dose for the shortest possible time to reduce side effects. If you need long-term treatment, you may also be given medicine to protect your stomach.
Keep any regular appointments with your doctor so they can check your progress, especially if you are taking indometacin long term.
If you have asthma, anti-inflammatory medicines can sometimes worsen breathing symptoms. Stop taking indometacin and contact your doctor if this happens.
Check with a pharmacist before taking any other medicines, including cold and flu remedies, as some contain anti-inflammatory painkillers that should not be taken with indometacin.
Tell your doctor, dentist, or surgeon about all the medicines you are taking before any treatment or operation.
How to store indometacin
Volver al contenidoMantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Volver al contenidoInformación importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Yellow Card website.
Preguntas frecuentes
Volver al contenidoHow long does it take for indomethacin to work?
Indomethacin usually starts working within 1-2 hours after taking a dose. For ongoing conditions, it may take a few days of regular use to feel the full effect.
Can you drink alcohol with indomethacin?
You should avoid or limit alcohol while taking indomethacin. Drinking alcohol can increase the risk of stomach irritation, ulcers, and bleeding, and make other side effects worse.
Is it safe to take indomethacin during pregnancy?
Indomethacin is not recommended during pregnancy, especially after 20 weeks as it may cause serious complications for the unborn baby, including kidney and heart problems.
Is indomethacin a strong painkiller?
Indomethacin is considered a strong anti-inflammatory painkiller compared with many other NSAIDs. It is often used for more severe pain and inflammation, but it can cause more side effects, so it is usually prescribed with care.
How much stronger is indomethacin than ibuprofen?
Indomethacin is generally considered stronger than ibuprofen at reducing inflammation and pain. Because it is more potent, it is often used when ibuprofen has not been effective, but it also carries a higher risk of side effects.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Lecturas adicionales y referencias
- Manufacturer's PIL, Indometacin suppositories 100 mg; Aspen Pharma Trading Ltd, The electronic Medicines Compendium. Dated August 2022.
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Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Próxima revisión: 18 Jun 2026
19 Jun 2023 | Última versión

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