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Indometacin for pain and inflammation

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Indometacin is a medicine called a non-steroidal anti-inflammatory drug. It is also known as 'an NSAID'.

Before you take indometacin, let your doctor know if you have ever had a bad reaction to any other anti-inflammatory painkiller.

Some people can feel dizzy while taking indometacin - this may affect your ability to use tools or machines and to drive.

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About indometacin

Tipo de medicamento

Non-steroidal anti-inflammatory drug (NSAID)

Utilizado para

Relief of pain and inflammation

También llamado

Indomethacin (in US; Indocin® Indocid®

Disponible como

Capsules, modified-release capsules and suppositories, oral liquid medicine (in US)

Anti-inflammatory painkillers like indometacin are sometimes called non-steroidal anti-inflammatory drugs (NSAIDs), or just 'anti-inflammatories'. Indometacin is used to treat painful conditions such as arthritis, sprains and strains, back pain, period (menstrual) pain, and gout pain.

Indometacin works by blocking the effect of chemicals in your body, called cyclo-oxygenase (COX) enzymes. These enzymes help to make other chemicals in the body, called prostaglandins. Some prostaglandins are produced at sites of injury or damage, and cause pain and inflammation. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which means pain and inflammation are eased.

Before taking indometacin

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking indometacin, it is important that your doctor knows:

  • Si padece asma o cualquier otro trastorno alérgico.

  • Si ha tenido alguna vez una úlcera de estómago o de duodeno, o si padece un trastorno inflamatorio intestinal como la enfermedad de Crohn o la colitis ulcerosa.

  • Si está embarazada o en periodo de lactancia.

  • If you are over 65 years of age.

  • Si tiene problemas hepáticos o renales.

  • Si padece una enfermedad cardiaca o un problema vascular o circulatorio.

  • Si tiene la tensión alta.

  • If you have a high blood sugar level or cholesterol level.

  • If you are a smoker.

  • If you have epilepsy, or Parkinson's disease, or a mental health problem.

  • Si tiene problemas de coagulación de la sangre.

  • If you have a connective tissue disorder, such as systemic lupus erythematosus. This condition is also called lupus, or SLE.

  • If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.

  • Si alguna vez ha tenido una reacción alérgica a cualquier otro AINE (como aspirina, naproxeno, diclofenaco e ibuprofeno), o a cualquier otro medicamento.

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How to take indometacin

  • Before you start taking indometacin, read the manufacturer's printed information leaflet from inside the pack. There are several strengths of indometacin capsule available. The manufacturer's leaflet will give you more information about the strength of capsule you have been given, and it will also provide you with a full list of the side-effects which you may experience.

  • Follow the instructions given by your doctor for taking indometacin. Your dose will depend upon the reason why you are taking it - you may be asked to take just one dose a day, or several doses each day. Your dose will be printed on the label of the pack, but if you are still unsure what to do, ask your pharmacist for advice.

  • Take indometacin capsules with a meal or after a snack. Doing this can help to prevent side-effects such as indigestion. Many people find it helps to swallow the capsules with a drink.

  • Si olvida tomar una dosis, tómela en cuanto se acuerde (a menos que sea casi la hora de la siguiente dosis, en cuyo caso omita la dosis olvidada). No tome dos dosis juntas para compensar la dosis olvidada.

Aproveche al máximo su tratamiento

  • Your doctor will try to prescribe you the lowest dose for the shortest time in order to reduce the risk of side-effects. If you need to take indometacin for a long time, your doctor may want to prescribe another medicine along with it to protect your stomach from irritation.

  • Try to keep any regular appointments with your doctor. This is so your doctor can check on your progress, and is especially important if you are taking indometacin for a long-term condition.

  • If you have asthma, symptoms such as wheeze or breathlessness can be made worse by anti-inflammatories. If this happens to you, you should stop taking indometacin and see your doctor as soon as possible.

  • If you buy any medicines, check with a pharmacist that they are safe to take with an anti-inflammatory. This is because you should not take indometacin with any other anti-inflammatory painkiller, some of which are available in cold and flu remedies which can be bought over the counter.

  • Si va a someterse a una operación o a un tratamiento dental, comunique a la persona que lleve a cabo el tratamiento qué medicamentos está tomando.

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Can indometacin cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with indometacin. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Común

indometacin side-effects

¿Qué puedo hacer si me ocurre esto?

Indigestion, heartburn (reflux), stomach pain

Make sure you take your doses after a meal. If the discomfort continues, speak with your doctor

Sentirse mal (náuseas) o estar enfermo (vómitos)

Comidas sencillas: evite los alimentos ricos o picantes.

Diarrhoea or constipation

Beber mucha agua

Sensación de mareo

Do not drive and do not use tools or machines when dizzy

Important: if you experience any of the following less common but more serious symptoms, stop taking indometacin and contact your doctor for advice straightaway:

  • Si tiene dificultades respiratorias, como sibilancias o disnea.

  • Si presenta cualquier signo de reacción alérgica, como hinchazón alrededor de la boca o la cara, o una erupción cutánea con picor intenso.

  • If you pass blood or black stools, vomit blood, or have severe tummy (abdominal) pains.

Si experimenta cualquier otro síntoma que considere que puede deberse al medicamento, consulte a su médico o farmacéutico.

How to store indometacin

  • Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.

  • Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.

Información importante sobre todos los medicamentos

Información importante sobre todos los medicamentos

No tome nunca más de la dosis prescrita. Si sospecha que usted u otra persona ha tomado una sobredosis de este medicamento, acuda al servicio de urgencias de su hospital. Llévese el envase, aunque esté vacío.

Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.

No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.

Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.

Informar de los efectos secundarios de un medicamento o vacuna

Si experimenta efectos secundarios, puede notificarlos en línea a través del sitio web de la Tarjeta Amarilla.

Lecturas complementarias y referencias

Historia del artículo

La información de esta página ha sido redactada y revisada por médicos cualificados.

  • Fecha prevista para la próxima revisión: 18 jun 2026
  • 19 Jun 2023 | Última versión

    Última actualización

    Michael Stewart, MRPharmS

    Revisado por expertos

    Sid Dajani
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