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Tabletas de Sulindac - un medicamento antiinflamatorio no esteroideo

NSAID

Clinical author's note Michael Stewart 19/02/2025: Sulindac tablets were discontinued in the UK in 2024. At the time of review there are no branded or generic products containing sulindac available in the UK. Sulindac may still be available in other countries. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.

Sulindac is a non-steroidal anti-inflammatory drug (also known as an NSAID).

Tell your doctor if you have ever had an allergic reaction to any other anti-inflammatory medicines.

Take the tablets after a meal or with a snack.

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About sulindac

Tipo de medicamento

Medicamento antiinflamatorio no esteroideo (AINE)

Usado para

Pain and inflammation in rheumatic disease and other muscle and joint conditions

Disponible como

Comprimidos

Anti-inflammatory painkillers like sulindac are sometimes called non-steroidal anti-inflammatory drugs (NSAIDs), or just 'anti-inflammatories'. Sulindac eases pain and reduces inflammation in rheumatic disease and other conditions where there is pain and swelling in the muscles or joints, such as gota.

Sulindac works by blocking the effect of chemicals called cyclo-oxygenase (COX) enzymes. These enzymes help to make other chemicals in the body, called prostaglandins. Some prostaglandins are produced at sites of injury or damage, and cause pain and inflammation. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which means pain and inflammation are eased.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking sulindac, it is important that your doctor or pharmacist knows:

  • Si tienes asma u otro trastorno alérgico.

  • Si alguna vez has tenido una úlcera gástrica o duodenal, o si tienes un trastorno inflamatorio intestinal como la enfermedad de Crohn o la colitis ulcerosa.

  • Si estás embarazada, intentando tener un bebé o amamantando.

  • If you are under 18 or over 65 years of age.

  • Si tienes problemas de hígado o riñón.

  • If you have ever had kidney stones.

  • Si tienes una afección cardíaca, o un problema con tus vasos sanguíneos o circulación.

  • Si tienes presión arterial alta.

  • Si alguna vez has tenido problemas de coagulación sanguínea.

  • Si tienes niveles altos de azúcar en sangre o colesterol.

  • If you are a smoker

  • If you have systemic lupus erythematosus (an inflammatory condition also called lupus, or SLE).

  • If you are taking other medicines, including those available to buy without a prescription, as well as herbal and complementary medicines.

  • Si alguna vez ha tenido una reacción alérgica a cualquier otro AINE (como aspirina, ibuprofeno, diclofenaco e indometacina), o a cualquier otro medicamento.

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  • Before you start taking sulindac, read the manufacturer's printed information leaflet from inside the pack. The leaflet will give you more information about the tablets and provide a full list of side-effects which you may experience from taking them.

  • Take sulindac exactly as your doctor has told you to. The usual dose is 200 mg taken twice a day. Your dose will be on the label of the pack to remind you.

  • Swallow the tablets with a drink of water

  • Take your doses with a snack or just after eating a meal, and drink plenty of water while you are on sulindac.

  • Try to take your doses at the same times each day, as this will help you to remember to take them.

  • If you forget to take a dose, take it as soon as you remember. However, if when you remember, it is nearly time for your next dose then leave out the forgotten dose. Do not take two doses together to make up for a missed dose.

  • Your doctor will try to prescribe you the lowest dose for the shortest time to reduce the risk of side-effects. Your doctor may also want to prescribe another medicine along with it to protect your stomach from irritation.

  • If you are taking sulindac for gout and your symptoms have not improved within seven days, you should let your doctor know about this.

  • Intenta mantener tus citas regulares con tu médico. Esto es para que tu médico pueda verificar tu progreso.

  • Some people taking sulindac have noticed that the colour of their urine changes slightly. If this happens to you, it is nothing you need to be concerned about.

  • If you have asthma, symptoms such as wheeze or breathlessness can be made worse by anti-inflammatories such as sulindac. If this happens to you, you should stop taking the tablets and see your doctor as soon as possible.

  • If you buy any medicines, check with a pharmacist that they are safe to take with an anti-inflammatory like sulindac.

  • Si vas a someterte a una operación o tratamiento dental, informa a la persona que realiza el tratamiento sobre los medicamentos que estás tomando.

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Junto con sus efectos útiles, la mayoría de los medicamentos pueden causar efectos secundarios no deseados, aunque no todos los experimentan. Estos generalmente mejoran a medida que su cuerpo se adapta al nuevo medicamento, pero hable con su médico o farmacéutico si alguno de los siguientes efectos secundarios persiste o se vuelve problemático.

Common sulindac side-effects

¿Qué puedo hacer si experimento esto?

Sentirse mal (náuseas) o estar enfermo (vómitos), diarrea

Mantente con alimentos simples. Bebe mucho líquido para reemplazar los fluidos perdidos

Indigestion, heartburn, tummy (abdominal) discomfort

Recuerda tomar las tabletas después de una comida si aún no lo estás haciendo. Si el malestar continúa, habla con tu médico

Other less common side-effects: headache, feeling dizzy or sleepy, nervousness, mood changes, difficulty sleeping, a spinning sensation (called vertigo), and ringing noises (called tinnitus)

Si alguno de estos se vuelve problemático, hable con su médico

Importante: if you experience any of the following less common but more serious symptoms, stop taking this medicine and contact your doctor for advice straightaway:

  • Si tienes alguna dificultad para respirar, como sibilancias o falta de aliento.

  • Si tienes algún signo de una reacción alérgica, como hinchazón alrededor de la boca o la cara, o una erupción cutánea severamente pruriginosa.

  • If you pass blood or black stools, bring up (vomit) blood, or have severe tummy (abdominal) pains.

Si experimenta otros síntomas que cree que pueden deberse a este medicamento, hable con su médico o farmacéutico.

  • Mantenga todos los medicamentos fuera del alcance y la vista de los niños.

  • Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.

Información importante sobre todos los medicamentos

Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda de inmediato al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.

Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.

Nunca guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, donde se encargarán de desecharlos por ti.

Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.

Informar efectos secundarios de un medicamento o vacuna

Si experimenta efectos secundarios, puede reportarlos en línea a través de Yellow Card website.

verificador de síntomas

¿Inseguro sobre mezclar medicamentos?

Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.

Lecturas adicionales y referencias

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About the author

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

Sid Dajani

Historial del artículo

La información en esta página está escrita y revisada por pares por clínicos calificados.

  • Siguiente revisión prevista: 19 de febrero de 2028
  • 19 de febrero de 2025 | Última versión

    Última actualización por

    Michael Stewart, MRPharmS

    Revisado por pares por

    Sid Dajani
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