
Can creatine supplements help build muscle?
Revisado por pares por Dr Krishna Vakharia, MRCGPÚltima actualización por Amberley DavisÚltima actualización 5 May 2023
Cumple con las directrices editoriales
- DescargarDescargar
- Compartir
- Language
- Discusión
- Versión en audio
When it comes to supporting muscle growth, creatine is one of the most popular natural supplements. Although questions over its safety have been raised, there is no evidence to suggest that creatine supplementation is unsafe in healthy individuals. In fact, the evidence suggests that creatine is a very effective way to build muscle.
En este artículo:
Videos seleccionados para Ejercicio y actividad física
Creatine supplementation is a hugely popular and effective way to support muscle strength. This has been shown in many estudios, when used alongside a healthy, protein-rich diet and regular strength/resistance training.
Continúa leyendo abajo
What is creatine?
Our bodies naturally produce creatine from amino acids. In turn, creatine helps to make a molecule called adenosine triphosphate (ATP). This substance is our bodies' main source of energy for muscle contractions.
95% of our bodies' creatine is stored in the cells of our muscles, and if our levels of creatine are low then the production of ATP is significantly reduced and our energy can be dramatically decreased. Without energy, we can't perform well during exercise, and without adequate resistance exercise our muscle tissues cannot go through the process of tearing and rebuilding. It is this process that increases muscle mass over time.
Aside from creatine supplementation, the factors that affect our bodies' creatine storage levels include natural food sources of creatine, how much muscle mass we have, how much we exercise, and the levels of protein and certain hormones like testosterone we have.
How does creatine help you to build muscle?
Volver al contenidoIncreasing the production of ATP is creatine's primary function during high-intensity exercise. However, there are several other ways that creatine helps us to build muscle. Creatine:
Increases cell signalling, which aids muscle repair and growth.
Raises levels of certain hormones ,which support muscle growth.
Reduces muscle breakdown, by reducing protein breakdown.
Supports cell hydration.
Reduces levels of the protein myostatin, which can slow muscle growth.
Continúa leyendo abajo
How effective are creatine supplements at supporting muscle growth?
Volver al contenidoMany estudios have looked at the effectiveness of consuming additional creatine through supplements, and found this to be effective for muscle building and strength.
These positive results are subject to the participants also following high-resistance training routines, and the effectiveness is compared to those who follow similar training exercises without supplementation.
The International Society of Sports Nutrition (ISSN) describes creatine supplementation as the most effective nutritional supplement currently available to athletes for increasing high-intensity exercise capacity and lean body mass during training.
Other health benefits of creatine
There are also other potential health benefits of increasing your creatine stores. As a small percentage of creatine is stored in the brain, an increase in creatine storage can protect against neurological diseases, such as Alzheimer's y Parkinson's. Creatine supplementation has therefore been studied as a possible therapeutic agent for such diseases.
Is creatine bad for you?
Volver al contenidoCreatine supplementation has received some bad press, and anecdotal claims of side-effects including cramping, increased risk of injury, deshidratación, and liver or kidney damage have spread.
However, there is no evidence to suggest that creatine supplements have caused these symptoms in healthy individuals. While it is true that athletes who have taken these supplements have experienced these problems, so have many athletes who haven't taken creatine. Research suggests that taking creatine bears no greater risk to developing these conditions.
For example, some estudios have found that supplementation does not increase the risk of injury or cramping.
The ISSN describes creatine supplementation as safe, effective, and ethical. This said, safety can never be guaranteed, especially when it is administered for a long period of time. A lot of data have focused on young, healthy adults. Groups such as the elderly or the very young are less studied.
Who should take creatine supplements?
Although creatine supplementation has been widely researched and tested for adults, fewer investigations have looked at its use and safety for adolescents and children. While no studies have found adverse effects in children, it's advised that creatine supplements should not be taken until after puberty.
There is also little research into their safety in pregnant or breastfeeding women, so it's best to avoid. You should avoid creatine supplements if you have chronic kidney disease or are taking medicines which have kidney damage as a potential side-effect.
For adults, creatine can be taken by anyone who is regularly participating in high-intensity exercise and using their muscles. Taking creatine won't benefit the kind of exercise that lasts more than 90 seconds, such as long-distance running.
Continúa leyendo abajo
How much creatine do you need?
Volver al contenidoReema Patel is a London-based dietitian. She shares her advice: "Supplementation of around 0.1 grams (g) per kilogram (kg) of body weight with creatine monohydrate is usually the recommended dose for those who regularly heavy resistance train."
You may also want to break your creatine supplement doses into two distinct phases:
The loading phase - involves taking slightly more creatine - 0.3 g per kg of body weight - for the first 3-7 days.
The maintenance phase - take around 0.1 g per kg of body weight to maintain the elevated creatine stores in your muscles.
ISSN recommends this method as the quickest way to increase muscle mass.
The method of cycling, where you alternate between using creatine supplements and not using them every couple of weeks, has not been scientifically proven to increase effectiveness.
Food sources of creatine
Volver al contenidoRemember, creatine supplements are only effective when taken in addition to natural sources of creatine. We get a large portion of creatine through the foods we eat.
Animal protein foods are good sources of creatine, including red meat, fish and lean meat.
Since creatine is mostly found in animal protein, people who follow a plant-based diet can instead aim to consume foods that are rich in amino acids, as these help our bodies to synthesise creatine.
Vegetarian foods containing amino acids include milk, cheese, and eggs, while vegan sources include white beans, walnuts, almonds, and watercress.
Selecciones del paciente para Ejercicio y actividad física

Vida saludable
Cómo correr una carrera de 10 km sin experiencia
Al comienzo del año, me aferraba a mi resolución de Año Nuevo de ponerme en forma y de alguna manera me inscribí en una carrera de 10 kilómetros alrededor de Kew Gardens en Londres. ¿Qué podría salir mal? Por un lado, no tenía experiencia ni idea de por dónde empezar. Afortunadamente, busqué consejo de algunos expertos. Combinando esto con mi propia experiencia de entrenamiento, aquí tienes algunos consejos para que puedas completar tu primer 10k.
por Georgia Gallant

Vida saludable
7 morning stretches to get you ready for the day
Most of us love the feeling of stretching first thing in the morning. However, chances are, you don't put much thought into what stretches you do. But did you know that there are specific stretches that will start your day off on the right note?
por Lynn Stephen
Continúa leyendo abajo
Historial del artículo
La información en esta página es revisada por pares por clínicos calificados.
Next review due: 5 May 2026
5 de mayo de 2023 | Última versión
26 Nov 2021 | Publicado originalmente
Escrito por:
Amberley Davis

Pregunta, comparte, conecta.
Navega por discusiones, haz preguntas y comparte experiencias en cientos de temas de salud.

¿Te sientes mal?
Evalúa tus síntomas en línea de forma gratuita
Suscríbete al boletín de Patient
Tu dosis semanal de consejos de salud claros y confiables, escritos para ayudarte a sentirte informado, seguro y en control.
Al suscribirte aceptas nuestros Política de Privacidad. Puedes darte de baja en cualquier momento. Nunca vendemos tus datos.