Tabletas de dietilstilbestrol

Revisado por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 2 de marzo de 2025

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Diethylstilbestrol can be taken by both men and women. As a guide the usual dose for men is 1-3 mg daily, and for women it is 10-20 mg daily. Follow your doctor's instructions carefully.

Side-effects of the treatment include feeling sick (nausea), swollen feet and ankles and an increased risk of blood clots. Impotence and breast enlargement can occur in men.

About diethylstilbestrol

Tipo de medicamento	An oestrogen
Usado para	Prostate cancer in men; breast cancer in women
Disponible como	Tabletas

Diethylstilbestrol is an oestrogen hormone treatment which helps to control the symptoms of some cancers.

It is sometimes used to treat cáncer de próstata, particularly if other therapies are not suitable. It is also occasionally used in women to treat cáncer de mama (providing you have been through the menopause).

Before taking diethylstilbestrol

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking diethylstilbestrol it is important that your doctor knows:

If you have a heart condition or any problems with your blood vessels.
Si tienes algún problema con el funcionamiento de tu hígado.
If it is for breast cancer and you have not been through the menopause. This is because diethylstilbestrol must not be taken by a woman who could become pregnant.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
Si alguna vez has tenido una reacción alérgica a un medicamento.

How to take diethylstilbestrol

Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about diethylstilbestrol, and will also provide you with a full list of the side-effects which you could experience from taking it.
Take diethylstilbestrol exactly as your doctor tells you to. Your doctor or pharmacist will tell you how many tablets to take a day, and these directions will also be printed on the label of the pack of tablets to remind you about what you have been told. As a guide, it is usual for men to take 1-3 mg daily, and for women to take 10-20 mg daily.
You can take the tablets either with or without food. Try to take your doses at the same time of day each day, as this will help you to remember to take your doses regularly.
Si olvida tomar una dosis, tómela tan pronto como lo recuerde. Si no lo recuerda hasta el día siguiente, omita la dosis olvidada del día anterior y tome la dosis que corresponde normalmente. No tome dos dosis al mismo tiempo para compensar una dosis olvidada.

Obteniendo el máximo de tu tratamiento

Intenta mantener tus citas regulares con tu médico. Esto es para que tu médico pueda verificar tu progreso.
If you are having an operation or any dental treatment, tell the person carrying out the treatment that you are taking diethylstilbestrol.

Can diethylstilbestrol cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with diethylstilbestrol. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Diethylstilbestrol side-effects	¿Qué puedo hacer si experimento esto?
Sentirse mal (náuseas)	Stick to simple foods - avoid rich or spicy meals. It may help to take your tablets after a meal
Swollen feet and ankles	Put your feet up whenever possible. Let your doctor know if this becomes troublesome
An increased risk of blood clots, impotence, breast enlargement (in men), bone pain (in women), withdrawal bleeding (in women), yellowing of the whites of your eyes or skin (jaundice)	Your doctor will discuss these with you before you start treatment

Si experimenta cualquier otro síntoma que crea que puede deberse a las tabletas, hable con su médico o farmacéutico para obtener más consejos.

How to store diethylstilbestrol

Mantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.

Información importante sobre todos los medicamentos

Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda de inmediato al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.

Si compras algún medicamento, consulta con un farmacéutico que sean adecuados para tomar con tus otros medicamentos.

Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.

No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, donde se encargarán de desecharlos por ti.

Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.

Informar efectos secundarios de un medicamento o vacuna

Si experimenta efectos secundarios, puede reportarlos en línea a través de Sitio web de Yellow Card.

Preguntas frecuentes

Can men taking diethylstilbestrol also experience side effects like breast enlargement?

Yes, men taking diethylstilbestrol may experience breast enlargement as a side effect. Your doctor will discuss this with you before you start treatment.

Are there different dosages of diethylstilbestrol for men and women?

Yes, standard dosages differ. As a guide, men typically take 1-3 mg daily, while women usually take 10-20 mg daily. Your doctor or pharmacist will confirm your specific dosage.

What should I do if I notice yellowing of my eyes or skin while taking diethylstilbestrol?

Yellowing of the whites of your eyes or skin (jaundice) is a potential side effect. Your doctor will discuss this with you before you start treatment. If you experience this, speak with your doctor for further advice.

Can diethylstilbestrol increase the risk of blood clots?

Yes, an increased risk of blood clots is a known side effect of diethylstilbestrol. Your doctor will discuss this potential risk with you before you begin treatment.

How should I dispose of any leftover or expired diethylstilbestrol tablets?

Do not keep out-of-date or unwanted medicines. You should take them to your local pharmacy, which will dispose of them for you safely.

Estas preguntas y respuestas han sido generadas a partir de la información en este artículo.

Lecturas adicionales y referencias

Manufacturer's PIL, Diethylstilbestrol 1 mg tablets; Brown and Burke Ltd, The electronic Medicines Compendium. Dated August 2021.
Medicamentos Completo BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.