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Anastrozole for breast cancer

Arimidex

Take one 1 mg tablet each day.

You can take the tablet before or after food.

The most common side-effects are headache, hot flushes, feeling sick (nausea), rash, joint pain, and feeling weak. These can occur in more than 1 in 10 women who take anastrozole.

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About anastrozole

Tipo de medicamento

An aromatase inhibitor

Usado para

Cáncer de mama

También llamado

Arimidex®

Disponible como

Comprimidos

Treatment options for women with cáncer de mama include surgery, radiotherapy, chemotherapy and hormone treatment. Often a combination of two or more of these treatments is used. Anastrozole is a hormone treatment.

Some breast cancers need the hormone oestrogen to grow. In women who have been through the menopause, the main source of oestrogen is through the change of sex hormones called androgens into oestrogen. An enzyme called 'aromatase' is needed for this change to occur. Anastrozole works by blocking (inhibiting) this enzyme. This reduces the amount of oestrogen in your body, which slows the growth of the cancer cells.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking anastrozole it is important that your doctor knows:

  • If you are still having menstrual periods - if you have not gone through the menopause you should not take anastrozole.

  • If you have been told you have a loss of bone density (osteoporosis).

  • If you have problems with the way your liver works, or problems with the way your kidneys work.

  • Si alguna vez has tenido una reacción alérgica a un medicamento.

  • If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines. It is particularly important that your doctor knows if you are taking a medicine called tamoxifen, or any oestrogen-containing medicines such as hormone replacement therapy (HRT).

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  • Before you start this treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about anastrozole and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take one 1 mg tablet of anastrozole each day, exactly as your doctor tells you to. Your dose will be printed on the label of the tablet pack to remind you.

  • You may take anastrozole at whatever time of day you find easiest to remember, but try to take your doses at the same time each day. This will help you to avoid missing any doses.

  • You can take the tablet before or after a meal.

  • If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, skip the missed dose. Do not take two doses together to make up for a forgotten dose.

  • Try to keep your regular appointments with your doctor or clinic. This is so your doctor can check on your progress. Anastrozole lowers the levels of female hormones in your body, which can reduce the strength of your bones. You will need to have bone density tests (before and during your treatment) to check for this.

  • Anastrozole is a long-term treatment so it's important to continue to take the tablets regularly unless your doctor tells you otherwise. It is likely you will need to take the tablets for five years.

  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking anastrozole.

  • Si compras algún medicamento, consulta con un farmacéutico que sea seguro tomarlo junto con tus otros medicamentos.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with anastrozole. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common anastrozole side-effects

¿Qué puedo hacer si experimento esto?

Hot flushes

Try to keep cool by wearing light, airy clothes

Feeling sick (nausea) or being sick (vomiting), loss of appetite

Mantente con comidas simples - evita alimentos ricos o picantes

Feeling weak or sleepy

This can happen when you first start treatment but quickly settles. Do not drive and do not use tools or machines if affected

Dolor de cabeza

Bebe mucha agua y pide a tu farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza continúan, informa a tu médico

Diarrea

Bebe mucha agua para reponer los líquidos perdidos

Skin rash, joint aches and pains, vaginal dryness or bleeding, hair thinning, carpal tunnel syndrome, 'pins and needles', taste changes

Si alguno de estos se vuelve problemático, hable con su médico para obtener consejo

Importante: There have been numerous reports of depression in women taking anastrozole. If you develop any signs of depression whilst being treated with anastrozole, make an appointment to see your doctor.

Si experimenta cualquier otro síntoma que crea que puede deberse a las tabletas, hable con su médico o farmacéutico para obtener más consejos.

  • Mantenga todos los medicamentos fuera del alcance y la vista de los niños.

  • Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.

Información importante sobre todos los medicamentos

Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.

Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.

No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.

Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.

MHRA - Reporte de reacciones adversas

Informe los efectos secundarios sospechosos de medicamentos, vacunas, cigarrillos electrónicos, incidentes con dispositivos médicos, productos defectuosos o falsificados (falsos) a la Agencia Reguladora de Medicamentos y Productos Sanitarios para garantizar un uso seguro y efectivo.

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Lecturas adicionales y referencias

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Historial del artículo

La información en esta página está escrita y revisada por pares por clínicos calificados.

  • Próxima revisión: 26 Nov 2026
  • 27 Nov 2023 | Última versión

    Última actualización por

    Michael Stewart, MRPharmS

    Revisado por pares por

    Sid Dajani
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