Cápsulas de Lomustina
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 5 Ago 2024
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Lomustine will be prescribed for you by a specialist doctor. It is usually taken on one day every 6-8 weeks.
Mantén tus citas regulares con tu médico o hospital. Necesitarás realizarte análisis de sangre con frecuencia.
Si crees que estás contrayendo una infección o si tienes una temperatura alta, por favor contacta a tu médico de inmediato.
De un vistazo
Lomustine is a chemotherapy medicine used to treat some cancers.
It is usually taken just once every 6-8 weeks, or sometimes split over three days.
It is important to avoid pregnancy or fathering a child during treatment and for some time after.
You will need regular blood tests and check-ups during your treatment.
Contact your doctor straight away if you develop a sore throat or a high temperature.
About lomustine capsules
Tipo de medicamento | Un medicamento de quimioterapia alquilante |
Usado para | Cáncer |
También llamado | Lomustine 'Medac', CeeNU® (USA) |
Disponible como | Cápsulas |
Lomustine is used to treat some cancers. It is given in particular to treat enfermedad de Hodgkin when other treatments have not proved effective. It is also prescribed for some brain, lung and skin cancers. Lomustine can be given alongside other medicines or treatments for cancer.
In cancer, certain cells in the body grow and multiply too fast. Medicamentos de quimioterapia like lomustine work by preventing the growth and division of cells. This reduces the number of cancer cells that your body makes.
Before taking lomustine
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking lomustine it is important that your doctor knows:
Si estás embarazada o amamantando.
Si tienes algún problema con el funcionamiento de tus riñones.
Si tienes una infección o te sientes mal.
If you have coeliac disease or wheat allergy.
Si tienes una rara enfermedad sanguínea hereditaria llamada porfiria.
Si alguna vez has tenido una reacción alérgica a un medicamento.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
How to take lomustine
Before you start this treatment, read any printed information you have been given by your doctor and the printed manufacturer's leaflet from inside your pack of capsules. These will give you more information about lomustine and will provide you with a full list of the side-effects which you may experience from taking it.
Lomustine will be prescribed for you by a specialist doctor who is experienced in treating your condition. Your doctor will calculate what dose is right for you and will tell you how many capsules to take. You will also be told on which day you should take them - it is important that you take lomustine exactly as your doctor tells you to. It is usually taken on just one day every 6-8 weeks (occasionally the dose can be split over three days instead). Your dose will be printed on the label of the pack to remind you about what the doctor said to you but if you are unsure about how to take the capsules, or if you have any other concerns, you should contact your doctor or hospital clinic for advice.
If you are sick (vomiting) shortly after taking a dose, please speak with your doctor or clinic for advice on what to do.
Obteniendo el máximo de tu tratamiento
You must try to keep your regular appointments with your doctor or hospital. This is so your doctor can check on your progress. You will need to have regular blood tests and check-ups during your treatment with lomustine.
It is important that you do not get pregnant or father a child while you are taking lomustine. Make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. Women should continue to use contraception for seven months after treatment has finished. Men should not father a child for at least 4 months after finishing treatment. If you would like to have children in the future, you should ask your doctor for advice about family planning before you begin taking lomustine. This is particularly important if you are a man, as there is a risk of reduced male fertility or sterility with lomustine treatment.
While you are taking lomustine and for six months after you have stopped the treatment, do not have any immunisations (vaccinations) without talking to your specialist doctor first. Lomustine lowers your body's resistance and there is a risk that you will get an infection from some vaccines.
Can lomustine cause problems?
Medicines used to treat cancer can have a number of side-effects, some of which can be delayed for several days or weeks after taking the medicine. Most chemotherapy medicines can lower the number of white cells in your blood, which increases the risk of you getting an infection. The risk of this is commonly highest 4-6 weeks after taking lomustine. You should take precautions to reduce the risk of getting an infection - you can do this by avoiding being with people who you know have an infection. If you think you are getting a sore throat or if you have a high temperature, please let your doctor know as soon as possible so that you can get some treatment straightaway.
Your doctor will discuss with you the possibility of unwanted side-effects from your treatment with lomustine, although not everyone experiences these. The table below contains some of the side-effects associated with lomustine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Please let your doctor know if you experience any of the following:
Lomustine side-effects | ¿Qué puedo hacer si experimento esto? |
Una temperatura alta o síntomas de una infección | Informa a tu médico sobre esto de inmediato |
Feeling sick (nausea) or being sick (vomiting), loss of appetite | Stick to simple foods - avoid fatty or spicy meals. Let your doctor know about this, as an anti-sickness medicine may help. If you are sick (vomiting) shortly after taking a dose, please speak with your doctor or clinic for advice on what to do |
Mouth ulcers, sore mouth | Cepillarse los dientes 2-3 veces al día con un cepillo de dientes suave y usar enjuague bucal regularmente puede ayudar a prevenir esto. Si las úlceras bucales se convierten en un problema, consulte a su médico |
Feeling disorientated, confused or tired; loss of hair (occurs rarely) | Si es problemático, informe a su médico |
Cambios en algunos análisis de sangre | Su médico verificará estos |
If you experience any other symptoms which you think may be due to the capsules, speak with your doctor or pharmacist for further advice.
How to store lomustine
Mantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
Si vas a someterte a una operación o tratamiento dental, informa a la persona que realiza el tratamiento sobre los medicamentos que estás tomando.
Si compras algún medicamento, siempre consulta con un farmacéutico para asegurarte de que sean adecuados para tomar junto con tus medicamentos recetados.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Sitio web de Yellow Card.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Preguntas frecuentes
What is coeliac disease or porphyria and why do they matter when taking lomustine?
Coeliac disease is a digestive condition where your small intestine becomes inflamed and unable to absorb nutrients, while porphyria is a rare inherited blood condition. It's important for your doctor to know if you have either of these conditions before you start lomustine, as they can affect how the medicine is used and any extra care that might be needed during your treatment.
Why do I need regular blood tests during my lomustine treatment?
Regular blood tests are necessary so your doctor can monitor your progress and check for any changes in your blood count. This is particularly important because lomustine can lower the number of white cells in your blood, increasing your risk of infection, and can also cause other changes to your blood tests.
How should I manage my diet if I experience nausea, vomiting, or loss of appetite?
If you experience nausea, vomiting, or loss of appetite while taking lomustine, it's advised to stick to simple foods and avoid fatty or spicy meals. You should also let your doctor know, as they may be able to prescribe an anti-sickness medicine to help manage these symptoms.
Can lomustine affect my ability to have children in the future?
Yes, lomustine can affect fertility. It is important that women use contraception for seven months after treatment, and men for at least four months after treatment. If you are a man, there is a risk of reduced fertility or sterility with lomustine treatment. If you wish to have children in the future, you should discuss family planning with your doctor before starting treatment.
What should I do if I forget to take my dose or take too much lomustine?
Lomustine should be taken exactly as your doctor tells you. If you are unsure about what to do, or if you suspect you or someone else might have taken an overdose, you should contact your doctor or hospital clinic for advice or go to the accident and emergency department of your local hospital immediately. Remember to take the medicine container with you.
Lecturas adicionales y referencias
- Summary of Product Characteristics (SPC), information for healthcare professionals, Lomustine 'Medac' 40 mg capsules; Medac GmBH, The electronic Medicines Compendium. Dated April 2024.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
Sobre el autorVer biografía completa

Michael Stewart, MRPharmS
Gerente de Revisión de Folletos de Medicamentos – Contratista, Farmacéutico
BPharm (Hons), MRPharmS
Michael es un farmacéutico comunitario que ejerce en Midlands y South Yorkshire con más de 20 años de experiencia asesorando sobre medicamentos y condiciones médicas. Tiene una sólida formación en capacitación en atención médica, habiendo producido e impartido cursos de formación para equipos de farmacia y personal de entornos de atención residencial, incluidas enfermeras. También ha contribuido a juntas asesoras de farmacia para la gestión de condiciones de baja gravedad en la comunidad.
Acerca del revisor

Sid Dajani
Sultan Dajani se graduó en la Escuela de Farmacia de Londres en 1994 y se convirtió en el miembro más joven elegido para el consejo de la Sociedad Real de Farmacia desde su fundación en 1842.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Artículo también disponible en Inglés, Alemán, Español, Francés, Italiano, Portugués, Hindi, Hebreo, Árabe, y Sueco.
Próxima revisión: 1 de agosto de 2027
5 Ago 2024 | Última versión

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