Estramustina para el cáncer de próstata
Estracyt
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSLast updated 19 Dic 2022
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To begin with, it is usual to be prescribed 4-6 capsules to take over the course of a day. This dose may be adjusted as your treatment continues.
Do not eat any food or drink any milk for one hour before you take estramustine, or for two hours afterwards.
If you feel suddenly unwell or experience any worrying symptoms, speak with your doctor or clinic straightaway.
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About estramustine
Tipo de medicamento | Un medicamento de quimioterapia alquilante |
Usado para | Treatment of advanced prostate cancer |
También llamado | Estracyt® |
Disponible como | Cápsulas |
Cáncer de próstata is a cancer which develops from cells in the prostate gland. It is the most common cancer in men in the UK. If the cancer spreads to other parts of your body, it is referred to as advanced prostate cancer. You may be offered anti-cancer medicine (chemotherapy) if you have advanced prostate cancer.
Estramustine is a chemotherapy medicine which reduces the number of cancer cells in your body by stopping cancer cells from multiplying. It also reduces the concentration of the male hormone testosterone. Cancer cells in other parts of your body need testosterone to grow and multiply, so this slows down the growth of the cancer which has spread.
Before taking estramustine
Volver al contenidoSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking estramustine it is important that your doctor or pharmacist knows:
If your partner is pregnant or breastfeeding.
If you have high blood pressure (hypertension).
If you have any heart problems.
If you have blood vessel disease, or if you have had any blood clot problems.
Si tienes niveles altos de azúcar en la sangre (diabetes mellitus).
If you have ever had a stomach or duodenal ulcer.
If you have epilepsy or if you get migraine headaches.
If you have been told you have high levels of calcium in your blood.
If you have any liver or kidney problems.
If you have problems with fluid retention, such as swollen feet or ankles.
Si tienes una infección o te sientes mal.
Si tienes un trastorno sanguíneo hereditario raro llamado porfiria.
Si está tomando o usando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
Si alguna vez has tenido una reacción alérgica a un medicamento.
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How to take estramustine
Volver al contenidoEstramustine will be prescribed for you by a doctor who is a specialist and experienced in treating your condition. Take the capsules exactly as your doctor tells you to. It is usual to be prescribed 4-6 capsules to take over the course of a day to begin with, although this may be adjusted as your treatment continues. Doses may range between 1-10 capsules taken daily. If you are unsure about how or when to take the capsules, or if you have any other concerns, you should contact your doctor or hospital clinic for advice.
You should take the capsules when your stomach is empty, which means taking them one hour before eating food, or waiting until two hours afterwards. This is because food prevents estramustine from being absorbed by your body, which means the medicine is much less effective for you.
Swallow the capsules with a drink of water. Do not open, crush or chew them.
Before you start this treatment, read any printed information you have been given by your doctor, and the leaflet from inside your pack. The leaflet will give you more information about estramustine and a full list of side-effects which you may experience from taking it.
If you are sick shortly after taking a dose, or if you forget a dose, contact your doctor or clinic for advice on what to do. You will be told whether to take the dose again, or wait until the next dose is due.
Do not drink any milk, or take any medicines containing calcium, magnesium or aluminium at the same time as you take estramustine. Some antacid and laxative preparations contain these, so ask your pharmacist for advice before you buy or take any 'over-the-counter' medicines.
Obteniendo el máximo de tu tratamiento
Volver al contenidoYou must try to keep your regular appointments with your doctor or hospital. This is so your doctor can check on your progress. You will need to have regular check-ups during your treatment, to monitor for unwanted side-effects.
Estramustine may lower the number of white cells in your blood, increasing the chance of you getting an infection. If possible, avoid people who you know are ill, and let your doctor know if you feel you are getting an infection.
While you are taking estramustine do not have any immunisations (vaccinations) without talking to your doctor first. Estramustine lowers your body's resistance so there is a chance that you may get an infection from some vaccines.
Si vas a someterte a una operación o tratamiento dental, informa a la persona que realiza el tratamiento sobre los medicamentos que estás tomando.
Although there is a risk of reduced fertility with estramustine treatment, it is important that you do not father a child while you are being treated. Make sure you have discussed these issues with your doctor if you are sexually active.
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Can estramustine cause problems?
Volver al contenidoAlong with their useful effects, most medicines can cause side-effects although not everyone experiences them. Before you start treatment with estramustine, your doctor will discuss with you the possibility of unwanted side-effects occurring. The table below lists some of the most common ones associated with estramustine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. You should let your doctor or clinic know as soon as possible if you experience any of the following:
Común estramustine side-effects - these affect fewer than 1 in 10 people who take this medicine | ¿Qué puedo hacer si experimento esto? |
Feeling sick (nausea) or being sick (vomiting), diarrhoea (during the first couple of weeks) | Drink plenty of water to replace lost fluids and stick to simple foods. Let your doctor know, as medicines can be prescribed to help |
Swollen feet and ankles | Si es problemático, hable con su médico |
(impotence), and breast swelling | Your doctor will discuss these with you before you start treatment |
Less common, but more serious side-effects | ¿Qué puedo hacer si experimento esto? |
Una temperatura alta (fiebre) o síntomas de una infección | Let your doctor know de inmediato |
Sudden chest pain, or any difficulties breathing | Let your doctor know de inmediato |
Si experimenta otros síntomas que cree que pueden deberse a este medicamento, hable con su médico o farmacéutico.
How to store estramustine
Volver al contenidoMantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Return any unused or unwanted capsules to your pharmacy to destroy. They will need special disposal.
Información importante sobre todos los medicamentos
Volver al contenidoInformación importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Yellow Card website.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Lecturas adicionales y referencias
- Manufacturer's PIL, Estracyt Capsules®; Pfizer Limited, The electronic Medicines Compendium. Dated October 2020.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
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Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Próxima revisión: 18 Jun 2027
19 Dic 2022 | Última versión

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