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Estramustina para el cáncer de próstata

Estracyt

To begin with, it is usual to be prescribed 4-6 capsules to take over the course of a day. This dose may be adjusted as your treatment continues.

Do not eat any food or drink any milk for one hour before you take estramustine, or for two hours afterwards.

If you feel suddenly unwell or experience any worrying symptoms, speak with your doctor or clinic straightaway.

De un vistazo

  • Estramustine is a chemotherapy medicine for advanced prostate cancer.

  • It reduces cancer cells and lowers testosterone, slowing cancer growth.

  • Take capsules on an empty stomach, one hour before or two hours after food.

  • Do not take with milk or medicines containing calcium, magnesium or aluminium.

  • Common side-effects include feeling sick, vomiting, diarrhoea, and swollen feet.

  • Tell your doctor straight away if you have a high temperature, chest pain, or breathing difficulties.

Selecciones de videos para Tratamiento del cáncer y medicamentos

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About estramustine

Tipo de medicamento

Un medicamento de quimioterapia alquilante

Usado para

Treatment of advanced prostate cancer

También llamado

Estracyt®

Disponible como

Cápsulas

Cáncer de próstata is a cancer which develops from cells in the prostate gland. It is the most common cancer in men in the UK. If the cancer spreads to other parts of your body, it is referred to as advanced prostate cancer. You may be offered anti-cancer medicine (chemotherapy) if you have advanced prostate cancer.

Estramustine is a chemotherapy medicine which reduces the number of cancer cells in your body by stopping cancer cells from multiplying. It also reduces the concentration of the male hormone testosterone. Cancer cells in other parts of your body need testosterone to grow and multiply, so this slows down the growth of the cancer which has spread.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking estramustine it is important that your doctor or pharmacist knows:

  • If your partner is pregnant or breastfeeding.

  • Si tienes presión arterial alta (hipertensión).

  • If you have any heart problems.

  • If you have blood vessel disease, or if you have had any blood clot problems.

  • Si tienes niveles altos de azúcar en la sangre (diabetes mellitus).

  • If you have ever had a stomach or duodenal ulcer.

  • If you have epilepsy or if you get migraine headaches.

  • If you have been told you have high levels of calcium in your blood.

  • If you have any liver or kidney problems.

  • If you have problems with fluid retention, such as swollen feet or ankles.

  • Si tienes una infección o te sientes mal.

  • Si tienes un trastorno sanguíneo hereditario raro llamado porfiria.

  • Si está tomando o usando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.

  • Si alguna vez has tenido una reacción alérgica a un medicamento.

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  • Estramustine will be prescribed for you by a doctor who is a specialist and experienced in treating your condition. Take the capsules exactly as your doctor tells you to. It is usual to be prescribed 4-6 capsules to take over the course of a day to begin with, although this may be adjusted as your treatment continues. Doses may range between 1-10 capsules taken daily. If you are unsure about how or when to take the capsules, or if you have any other concerns, you should contact your doctor or hospital clinic for advice.

  • You should take the capsules when your stomach is empty, which means taking them one hour before eating food, or waiting until two hours afterwards. This is because food prevents estramustine from being absorbed by your body, which means the medicine is much less effective for you.

  • Swallow the capsules with a drink of water. Do not open, crush or chew them.

  • Before you start this treatment, read any printed information you have been given by your doctor, and the leaflet from inside your pack. The leaflet will give you more information about estramustine and a full list of side-effects which you may experience from taking it.

  • If you are sick shortly after taking a dose, or if you forget a dose, contact your doctor or clinic for advice on what to do. You will be told whether to take the dose again, or wait until the next dose is due.

  • Do not drink any milk, or take any medicines containing calcium, magnesium or aluminium at the same time as you take estramustine. Some antacid and laxative preparations contain these, so ask your pharmacist for advice before you buy or take any 'over-the-counter' medicines.

  • You must try to keep your regular appointments with your doctor or hospital. This is so your doctor can check on your progress. You will need to have regular check-ups during your treatment, to monitor for unwanted side-effects.

  • Estramustine may lower the number of white cells in your blood, increasing the chance of you getting an infection. If possible, avoid people who you know are ill, and let your doctor know if you feel you are getting an infection.

  • While you are taking estramustine do not have any immunisations (vaccinations) without talking to your doctor first. Estramustine lowers your body's resistance so there is a chance that you may get an infection from some vaccines.

  • Si vas a someterte a una operación o tratamiento dental, informa a la persona que realiza el tratamiento sobre los medicamentos que estás tomando.

  • Although there is a risk of reduced fertility with estramustine treatment, it is important that you do not father a child while you are being treated. Make sure you have discussed these issues with your doctor if you are sexually active.

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Along with their useful effects, most medicines can cause side-effects although not everyone experiences them. Before you start treatment with estramustine, your doctor will discuss with you the possibility of unwanted side-effects occurring. The table below lists some of the most common ones associated with estramustine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. You should let your doctor or clinic know as soon as possible if you experience any of the following:

Común

estramustine side-effects - these affect fewer than 1 in 10 people who take this medicine

¿Qué puedo hacer si experimento esto?

Feeling sick (nausea) or being sick (vomiting), diarrhoea (during the first couple of weeks)

Drink plenty of water to replace lost fluids and stick to simple foods. Let your doctor know, as medicines can be prescribed to help

Swollen feet and ankles

Si es problemático, hable con su médico

Disfunción eréctil

(impotence), and breast swelling

Your doctor will discuss these with you before you start treatment

Less common, but more serious side-effects

¿Qué puedo hacer si experimento esto?

Una temperatura alta (fiebre) o síntomas de una infección

Informe a su médico

de inmediato

Sudden chest pain, or any difficulties breathing

Informe a su médico

de inmediato

Si experimenta otros síntomas que cree que pueden deberse a este medicamento, hable con su médico o farmacéutico.

  • Mantenga todos los medicamentos fuera del alcance y la vista de los niños.

  • Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.

  • Return any unused or unwanted capsules to your pharmacy to destroy. They will need special disposal.

Información importante sobre todos los medicamentos

Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.

Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.

No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.

Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.

Informar efectos secundarios de un medicamento o vacuna

Si experimenta efectos secundarios, puede reportarlos en línea a través de Sitio web de Yellow Card.

verificador de síntomas

¿Inseguro sobre mezclar medicamentos?

Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.

Preguntas frecuentes

What type of cancer does estramustine treat, and how does it work?

Estramustine is an alkylating chemotherapy medicine used to treat advanced prostate cancer. This is prostate cancer that has spread to other parts of the body. It works by reducing the number of cancer cells in your body and also by lowering the concentration of the male hormone testosterone, which cancer cells need to grow and multiply. By doing this, it slows down the growth of the cancer.

Why is it important to take estramustine on an empty stomach?

You should take estramustine capsules when your stomach is empty, either one hour before eating food or two hours after. This is because food can prevent the medicine from being properly absorbed by your body, making it much less effective in treating the cancer.

Can I take other medicines or supplements while on estramustine?

You need to tell your doctor or pharmacist about all other medicines you are taking, including those bought without a prescription, herbal remedies, and complementary medicines. Specifically, you should not drink milk or take any medicines containing calcium, magnesium, or aluminium at the same time as estramustine. Some antacids and laxatives contain these ingredients, so check with your pharmacist before taking any 'over-the-counter' medicines.

What should I do if I forget to take a dose, or if I am sick after taking it?

If you are sick shortly after taking a dose, or if you forget a dose, you should contact your doctor or hospital clinic for advice. They will tell you whether to take the dose again or wait until your next scheduled dose.

Does estramustine have an impact on fertility or sexual activity?

Estramustine treatment carries a risk of reduced fertility. If you are sexually active, it is important to discuss these issues with your doctor, as you must not father a child while you are undergoing treatment.

What should I do if I feel unwell with a high temperature or symptoms of an infection while taking estramustine?

If you develop a high temperature (fever) or any symptoms of an infection, you should let your doctor know straight away. Estramustine can lower your white blood cell count, which increases your chance of getting an infection.

Are there any specific vaccines I should avoid while on estramustine?

While taking estramustine, you should not have any immunisations (vaccinations) without first speaking to your doctor. Because estramustine lowers your body's resistance, there is a risk that you could get an infection from some vaccines.

How should estramustine capsules be stored, and what should I do with unused medicine?

Estramustine capsules should be kept in a cool, dry place, away from direct heat and light, and out of the reach and sight of children. Any unused or unwanted capsules should be returned to your pharmacy for proper disposal, as they require special handling.

Lecturas adicionales y referencias

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Sobre el autorVer biografía completa

Imagen del autor

Michael Stewart, MRPharmS

Gerente de Revisión de Folletos de Medicamentos – Contratista, Farmacéutico

BPharm (Hons), MRPharmS

Michael es un farmacéutico comunitario que ejerce en Midlands y South Yorkshire con más de 20 años de experiencia asesorando sobre medicamentos y condiciones médicas. Tiene una sólida formación en capacitación en atención médica, habiendo producido e impartido cursos de formación para equipos de farmacia y personal de entornos de atención residencial, incluidas enfermeras. También ha contribuido a juntas asesoras de farmacia para la gestión de condiciones de baja gravedad en la comunidad.

Acerca del revisor

Imagen del autor

Sid Dajani

Sultan Dajani se graduó en la Escuela de Farmacia de Londres en 1994 y se convirtió en el miembro más joven elegido para el consejo de la Sociedad Real de Farmacia desde su fundación en 1842.

Historial del artículo

La información en esta página está escrita y revisada por pares por clínicos calificados.

  • Próxima revisión: 18 Jun 2027
  • 19 Dic 2022 | Última versión

    Última actualización por

    Michael Stewart, MRPharmS

    Revisado por pares por

    Sid Dajani
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