Triamterene - a 'water' tablet or diuretic
Dyrenium
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 5 May 2025
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Clinical author's note Michael Stewart 15/06/2022: Triamterene capsules were discontinued in the UK in November 2021. Currently triamterene is only available in the UK in combination with another diuretic medicine called chlortalidone. At the time of review there are no branded or generic products solely containing triamterene available in the UK. Products may still be available in other countries. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.
Triamterene is a 'water' tablet (diuretic) - it will make you want to go to the toilet more often to pass urine.
It may cause your urine to look slightly blue in some lights - this is harmless.
Cualquier efecto secundario suele ser leve.
De un vistazo
Triamterene is a potassium-sparing diuretic used to treat water retention (oedema).
It makes you pass more urine, reducing fluid build-up in your body.
Take triamterene exactly as your doctor tells you, usually no later than mid-afternoon.
Your doctor will regularly check your blood salt levels.
Avoid foods with high potassium content, like 'salt substitutes'.
Common side effects include feeling sick, vomiting, or diarrhoea.
Tell your doctor if you have kidney or liver problems or are pregnant.
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About triamterene
Tipo de medicamento | A potassium-sparing diuretic |
Usado para | Water retention (oedema) |
También llamado | Dyrenium® (USA); |
Disponible como | Triamterene 50 mg/ chlortalidone 50 mg tablets |
Triamterene belongs to the group of medicines known as potassium-sparing diuretics. A diuretic is a medicine which increases the amount of urine that you pass out from your kidneys. They are often referred to as 'water' tablets. Triamterene is called a potassium-sparing diuretic because, unlike some other diuretics, it does not cause your body to lose potassium. It is used to treat water retention (oedema), and it is also given alongside other diuretics to reduce the amount of potassium they cause your body to lose.
Oedema occurs when fluid leaks out of your blood vessels, causing swelling in the tissues of your lungs, feet or ankles. This makes you feel breathless and your legs feel puffy. It is commonly caused by heart failure or liver disease. Triamterene prevents the build-up of this fluid by increasing the amount of urine your kidneys produce.
In the UK, triamterene is only available in combination with another diuretic medicine called chlortalidone. This combination can help cut down on the number of tablets you need to take each day.
Before taking triamterene
Volver al contenidoSome medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking triamterene it is important that your doctor knows:
Si estás embarazada o amamantando.
If you have problems with the way your kidneys work, or any difficulty passing urine.
Si tienes algún problema con el funcionamiento de tu hígado.
Si tienes diabetes.
If you have attacks of gout.
If you have been told by a doctor that you have high levels of potassium in your blood.
If you have a problem with your adrenal glands, called Enfermedad de Addison.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que se pueda comprar sin receta, así como medicamentos herbales y complementarios.
Si alguna vez has tenido una reacción alérgica a un medicamento.
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How to take triamterene
Volver al contenidoBefore you start the treatment, read the manufacturer's printed information leaflet from inside your pack. It will give you more information about triamterene and will also provide you with a full list of side-effects which you could experience from taking it.
Take triamterene exactly as your doctor tells you to. It is usual, to begin with, to take 3-5 capsules a day divided into two doses, one dose with your breakfast and the other at lunchtime. After the first week or so, your doctor is likely to ask you to take the capsules on alternate days only. The directions for taking your doses will be printed on the label of the pack to remind you about what the doctor said to you.
Diuretics are best taken no later than mid-afternoon. This is because you will find you may need to go to the toilet a couple of times after taking it and this will disturb your sleep if you take it too late in the day.
Swallow the capsules with a drink of water. You can take triamterene either with or without food.
If you forget to take a dose of triamterene, take it when you remember if it is only a few hours late. If it is after mid-afternoon, leave out the forgotten dose completely and take your next dose when it is due. Do not take two doses at the same time to make up for a missed dose.
Obteniendo el máximo de tu tratamiento
Volver al contenidoTry to keep your regular appointments with your doctor. This is so your doctor can check on your progress. The balance of salts in your blood may be upset by triamterene so your doctor may want you to have a blood test from time to time to check for this.
Diuretics help you to lose water, so you can breathe and move more easily. If, however, you lose too much fluid, you may become lacking in fluid in the body (dehydrated). This will make you feel thirsty and make your skin look and feel dry. Let your doctor know if this happens, as your dose may need to be adjusted.
Because triamterene is a potassium-sparing diuretic, you should try to avoid things with a high potassium content, such as 'salt substitutes'. This is so the level of potassium in your body does not become too high.
Treatment with diuretics is usually long-term, so continue to take triamterene unless your doctor advises you otherwise.
If you buy any medicines 'over the counter', please check with a pharmacist that they are suitable for you to take alongside your prescribed medicines.
Triamterene can cause your urine to look slightly blue in some lights - this is harmless and nothing to be concerned about.
Si también está tomando hidroclorotiazida en combinación con este medicamento
Los estudios han sugerido que tomar dosis más altas de hidroclorotiazida durante largos períodos de tiempo puede aumentar el riesgo de ciertos tipos de cáncer de piel.
Informe a su médico si alguna vez ha sido tratado por cáncer de piel.
Informe a su médico sobre cualquier lunar nuevo o cambiado, o marcas preocupantes en su piel.
Use a sunscreen in strong sunlight. Do not use sunbeds.
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Can triamterene cause problems?
Volver al contenidoAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the common ones associated with triamterene. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common triamterene side-effects (these affect fewer than 1 in 10 people) | ¿Qué puedo hacer si experimento esto? |
Sentirse mal (náuseas) o estar enfermo (vómitos) | Stick to simple foods - avoid fatty or spicy meals. Try taking the capsules after a meal or a snack |
Diarrea | Bebe mucha agua para reponer los líquidos perdidos |
Cambios en los resultados de algunos análisis de sangre | Your doctor will check for this from time to time |
Si experimenta cualquier otro síntoma que crea que puede deberse a las cápsulas, por favor hable con su médico o farmacéutico para obtener más consejos.
How to store triamterene
Volver al contenidoMantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Volver al contenidoInformación importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
If you are due to have an operation or any dental treatment, please tell the person carrying out the treatment which medicines you are taking.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Sitio web de Yellow Card.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Preguntas frecuentes
What is the main difference between triamterene and other diuretics?
Triamterene is known as a 'potassium-sparing' diuretic. This means that, unlike some other diuretics which can cause your body to lose potassium, triamterene does not have this effect. It can also be given with other diuretics to help prevent them from causing potassium loss.
Why do I need to be careful about foods high in potassium while taking triamterene?
Because triamterene is a potassium-sparing diuretic, it helps your body retain potassium. To prevent your potassium levels from becoming too high, you should try to avoid consuming foods or products with a high potassium content, such as 'salt substitutes'.
What should I do if I become very thirsty or my skin feels dry while taking this medication?
These symptoms could indicate that you are losing too much fluid and becoming dehydrated. You should let your doctor know if this happens, as your dose of triamterene may need to be adjusted.
How often will I need to see my doctor while taking triamterene?
You should try to keep your regular appointments with your doctor so they can monitor your progress. Triamterene can affect the balance of salts in your blood, so your doctor may ask you to have blood tests periodically to check these levels.
If I notice my urine has a blue tint, should I be concerned?
No, if your urine looks slightly blue in some lights while taking triamterene, this is harmless and there is no need to be concerned.
What if I miss a dose of triamterene?
If you remember within a few hours of the missed dose, you should take it. However, if it's already after mid-afternoon, you should skip that dose completely and take your next dose at its scheduled time. Never take a double dose to make up for a forgotten one.
Can I take other medicines, including over-the-counter remedies, with triamterene?
Before taking any other medicines, including those you can buy without a prescription, or any herbal and complementary medicines, you should check with a pharmacist to ensure they are suitable to take alongside your prescribed triamterene.
Lecturas adicionales y referencias
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
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Sobre el autorVer biografía completa

Michael Stewart, MRPharmS
Gerente de Revisión de Folletos de Medicamentos – Contratista, Farmacéutico
BPharm (Hons), MRPharmS
Michael es un farmacéutico comunitario que ejerce en Midlands y South Yorkshire con más de 20 años de experiencia asesorando sobre medicamentos y condiciones médicas. Tiene una sólida formación en capacitación en atención médica, habiendo producido e impartido cursos de formación para equipos de farmacia y personal de entornos de atención residencial, incluidas enfermeras. También ha contribuido a juntas asesoras de farmacia para la gestión de condiciones de baja gravedad en la comunidad.
Acerca del revisor

Sid Dajani
Sultan Dajani se graduó en la Escuela de Farmacia de Londres en 1994 y se convirtió en el miembro más joven elegido para el consejo de la Sociedad Real de Farmacia desde su fundación en 1842.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Next review due: 5 May 2028
5 May 2025 | Última versión

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