Hydralazine for high blood pressure
Apresoline
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSLast updated 12 Dic 2022
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Hydralazine is used to control high blood pressure (hypertension).
Treatment with hydralazine is usually long-term.
The most common side-effects are headaches and being aware of your heartbeat.
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About hydralazine
Tipo de medicamento | Un medicamento antihipertensivo vasodilatador |
Usado para | The treatment of high blood pressure |
También llamado | Apresoline® |
Disponible como | Comprimidos |
Although many people with presión arterial alta (hipertensión) do not feel unwell, it is still important that high blood pressure be treated. If left untreated, high blood pressure is a risk factor that can increase your chance of developing heart disease, a stroke, and other serious conditions. Hydralazine will be prescribed alongside other medicines to control high blood pressure.
Hydralazine works by relaxing the muscles in the walls of your blood vessels. This means that your blood vessels widen, which reduces your blood pressure and allows blood and oxygen to circulate more freely around your body. Hydralazine will only be prescribed for you if other treatments are not suitable or effective, as it can increase the amount of water and salt in your body and can increase your heart rate. The other medicines you are prescribed to take alongside it will help to control these side-effects.
Hydralazine is occasionally prescribed by hospital doctors for other heart conditions. If you have been prescribed it for a reason other than high blood pressure, speak with your doctor if you have any questions about your treatment.
Before taking hydralazine
Volver al contenidoSome medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking hydralazine it is important that your doctor knows:
If you have a condition called systemic lupus erythematosus. This is an inflammatory condition also called lupus, or SLE.
Si tienes algún problema con el funcionamiento de tu hígado, o si tienes algún problema con el funcionamiento de tus riñones.
If you have a problem with your blood vessels, such as coronary artery disease or cerebrovascular disease.
if you have a heart condition or have recently had a heart attack.
Si estás embarazada o amamantando.
Si tienes un trastorno sanguíneo hereditario raro llamado porfiria.
Si está tomando o usando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
If you have ever had an allergic reaction to any medicine.
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How to take hydralazine
Volver al contenidoBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about hydralazine and will provide you with a full list of the side-effects which you could experience from taking the tablets.
Take hydralazine exactly as your doctor tells you to. It is usual to take one tablet twice a day. Try to take your doses at similar times of day each day, as this will help you to remember to take them regularly. There are two strengths of hydralazine tablet - it is usual to take the 25 mg strength tablet to begin with, but this may later be increased to the higher 50 mg strength tablet. Increasing your dose gradually allows your doctor to make sure that you have the dose that best helps your condition, but also keeps unwanted side-effects to a minimum.
Swallow the tablet whole with a drink of water. You can take hydralazine either with or without food.
If you forget to take a dose at your usual time, take it as soon as you remember unless your next dose is due. If your next dose is due then take the dose which is due but leave out the forgotten one. Do not take two doses together to make up for a missed dose.
Obteniendo el máximo de tu tratamiento
Volver al contenidoTry to keep your regular appointments with your doctor. This is so your doctor can check on your progress. You will need to have regular blood pressure measurements, and also some blood and urine tests from time to time.
Your doctor will advise you on what lifestyle changes you can make to help your condition. These could include losing weight if you are overweight, taking regular physical activity, eating a healthy diet, cutting back on the amount of alcohol you drink, stopping smoking, and reducing the amount of salt in your meals and caffeine in your drinks. It is important that you follow any advice you are given.
If you buy any medicines, check with a pharmacist that they are suitable for you to take. This is because some medicines (particularly some anti-inflammatory painkillers) can interfere with the way hydralazine works.
Treatment with hydralazine is usually long-term unless you experience an adverse effect. Continue to take the tablets unless you are advised otherwise by your doctor.
If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking hydralazine. This is because some anaesthetics can affect your blood pressure.
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Can hydralazine cause problems?
Volver al contenidoAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with hydralazine. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common hydralazine side-effects (estos afectan a más de 1 de cada 10 personas) | ¿Qué puedo hacer si experimento esto? |
Dolor de cabeza | Bebe mucha agua y pide a tu farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza continúan, consulta a tu médico |
A fast heartbeat, the sensation of having a 'thumping heart' (palpitations) | If you are concerned, speak with your doctor |
Común hydralazine side-effects (estos afectan a menos de 1 de cada 10 personas) | ¿Qué puedo hacer si experimento esto? |
Feeling flushed, swollen feet or ankles, chest pain | If any of these symptoms continue or cause you concern, speak with your doctor |
Sensación de mareo | If this happens, sit down for a while until you feel better. Do not drive and do not use tools or machines while affected. Do not drink alcohol |
Sentirse mal (náuseas) o estar enfermo (vómitos), diarrea | Eat simple meals and drink plenty of water to replace lost fluids |
Joint or muscle pain | Speak with your doctor about this as soon as possible. It may be an early sign of systemic lupus erythematosus-like syndrome |
Si experimenta cualquier otro síntoma que crea que puede deberse a las tabletas, por favor hable con su médico o farmacéutico para obtener más consejos.
How to store hydralazine
Volver al contenidoMantenga todos los medicamentos fuera de la vista y del alcance de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Volver al contenidoInformación importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
Do not keep-out-of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Yellow Card website.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Lecturas adicionales y referencias
- Manufacturer's PIL, Hydralazine Tablets 25 mg and 50 mg; Accord-UK Ltd, The electronic Medicines Compendium. Dated October 2021.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
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Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Próxima revisión: 11 Jun 2027
12 Dic 2022 | Última versión

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