Nicorandil for angina
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSLast updated 17 Dic 2024
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The usual dose is one tablet (either 10 mg or 20 mg) twice daily.
The most common side-effects are headache and feeling dizzy. These should settle as you get used to the tablets.
Store the tablets in their original container - do not transfer from the blister pack into another container.
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About nicorandil
Tipo de medicamento | An anti-anginal medicine (a potassium-channel activator) |
Usado para | To prevent angina chest pain |
Disponible como | Comprimidos |
Angina is a pain that comes from the heart. It is usually caused by the narrowing of one or more of the arteries that supply blood to your heart. This narrowing reduces the blood supply to parts of your heart muscle. When your heart needs more blood and oxygen than it can get through the narrowed arteries (for example, when you walk fast or climb stairs), you feel angina pain.
Nicorandil works by relaxing (widening) your blood vessels. This increases the supply of blood and oxygen to your heart and helps to reduce the number of angina attacks you have. It can also reduce the risk of further heart conditions. You will be prescribed nicorandil if other (more frequently used) medicines are not suitable for you, or if they have not been sufficient to control your chest pains.
Before taking nicorandil
Volver al contenidoSome medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking nicorandil it is important that your doctor knows:
Si estás embarazada o amamantando.
If you have low blood pressure.
If you have recently had a heart attack, or been told you have heart failure.
If you have a problem with fluid build-up in your lungs, called pulmonary oedema.
Si alguna vez has tenido una reacción alérgica a un medicamento.
Si está tomando o usando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
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How to take nicorandil
Volver al contenidoBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about nicorandil and will also provide you with a full list of side-effects which you could experience from taking it.
Take nicorandil exactly as your doctor tells you to. It is usual to take one tablet (either 10 mg or 20 mg) twice daily, in the morning and evening. When starting your treatment your doctor may give you a smaller dose (such as half a tablet) and then increase it after a short while. This will help avoid any unwanted side-effects, particularly headache. Your doctor will tell you what dose is right for you, and this information will be printed on the label of the pack of tablets to remind you about what the doctor said to you.
Try to take your tablets at the same times each day, as this will help you to remember to take your doses regularly. You can take nicorandil tablets either before or after meals. Swallow the tablet with a drink of water.
Si olvida tomar una dosis, tómela tan pronto como lo recuerde (a menos que esté cerca la hora de su próxima dosis, en cuyo caso omita la dosis olvidada). No tome dos dosis juntas para compensar una dosis olvidada.
Obteniendo el máximo de tu tratamiento
Volver al contenidoNicorandil tablets are not suitable to take to relieve pain if you are having an angina attack. Your doctor will also prescribe a nitrate medicine, such as glyceryl trinitrate (GTN), for you to take if this happens. If after using GTN your pain has not eased within a few minutes, call for an ambulance.
Intenta mantener tus citas regulares con tu médico. Esto es para que tu médico pueda verificar tu progreso.
Treatment with nicorandil is usually long-term unless you experience an adverse effect. Continue to take the tablets unless you are advised otherwise by your doctor.
Nicorandil may cause you to feel faint or dizzy, particularly when you first start taking it. Do not drive and do not use tools or machines until you know how you react. It is best not to drink alcohol while you are on nicorandil, as alcohol will increase these feelings of dizziness.
If you buy any medicines 'over the counter', please check with a pharmacist that they are suitable for you to take with your prescribed medicines, as some anti-inflammatory painkillers may not be. It is very important that you do not take any medicines for disfunción eréctil while you are on nicorandil, unless they have been prescribed by your doctor.
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Can nicorandil cause problems?
Volver al contenidoAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with nicorandil. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common nicorandil side-effects (these affect more than 1 in 10 people) | ¿Qué puedo hacer si experimento esto? |
Dolor de cabeza | This is very common when you first start nicorandil, but it should soon settle down. In the meantime, ask your doctor or pharmacist to recommend a suitable painkiller |
Common nicorandil side-effects (these affect fewer than 1 in 10 people) | ¿Qué puedo hacer si experimento esto? |
Sentirse mal (náuseas) o estar enfermo (vómitos) | Eat simple meals until this settles down - avoid rich or spicy food. Try taking the tablet after a meal if you are not already doing so |
Feeling dizzy or weak | No conduzca ni utilice herramientas o máquinas mientras esté afectado |
Feeling flushed, increased heart rate | Si alguno de estos se vuelve problemático, hable con su médico |
Importante: some people taking nicorandil tablets have developed ulcers - particularly mouth, eye or skin ulcers. Although this is a rare side-effect, you should let your doctor know straightaway if you develop any ulcers, or if you notice any blood in your stools when you go to the toilet.
Si experimenta cualquier otro síntoma que crea que puede deberse a las tabletas, hable con su médico o farmacéutico para obtener más consejos.
How to store nicorandil
Volver al contenidoMantenga todos los medicamentos fuera del alcance y la vista de los niños.
Store in a cool, dry place, away from direct heat and light. Keep the blister strip in the outer carton. Do not transfer nicorandil tablets from the blister strips into other containers (including dosette boxes). This is because the original packaging contains a desiccant capsule to keep the tablets fresh and without it they will degrade quickly. Do not swallow the desiccant capsule by mistake.
Información importante sobre todos los medicamentos
Volver al contenidoInformación importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
If you are due to have an operation or any dental treatment, please tell the person carrying out the treatment which medicines you are taking.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Yellow Card website.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Lecturas adicionales y referencias
- Manufacturer's PIL, Nicorandil 10 mg and 20 mg Tablets; Dexcel Pharma Ltd, The electronic Medicines Compendium. Dated January 2022.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Siguiente revisión prevista: 17 de diciembre de 2027
17 Dic 2024 | Última versión

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