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Colestipol - a lipid-lowering medicine

Colestid

Clinical author's note Michael Stewart 05/01/2024: Colestid® sachets were discontinued in the United Kingdom in January 2023. At the time of review there are no licensed products containing colestipol available in the UK. Colestipol tablets and sachets may still be available in other countries or as special order products. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.

Take each sachet of colestipol granules mixed into at least 100 ml of liquid or soft food such as fruit juice, skimmed milk, soup, or yoghurt.

Avoid taking any other medicines at the same time as colestipol. Either take your other medicines one hour before colestipol, or wait until 4-6 hours afterwards.

The main side-effect of colestipol is constipation.

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About colestipol

Tipo de medicamento

A bile acid binder (sequestrant)

Utilizado para

Lowering cholesterol and other lipids

También llamado

Colestid® (Discontinued in UK)

Disponible como

Tablets and sachets of granules

Colestipol is available as sachets of granules which work in the body as a bile acid sequestrant. This means that it binds to bile acids in your digestive system. It prevents the bile acids from being recycled (reabsorbed) into your body. This action can be useful for people who have higher than normal levels of lipids in their blood.

Lipid is another word for fat. Cholesterol is a type of lipid. Lipids are easily stored in your body and serve as a source of energy. They are made naturally in your body from the food you eat. When the concentration of lipids in your blood is too high, it is called hyperlipidaemia. By taking colestipol, it prevents your bile acids from being reabsorbed and, as a consequence, your liver has to make more bile acids. It does this by using certain lipids from your blood. This lowers the amount of lipids in your blood and reduces your risk of heart and blood vessel disease.

Before taking colestipol

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking colestipol it is important that your doctor knows:

  • Si está embarazada, esperando un bebé o en período de lactancia.

  • Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que pueda adquirirse sin receta, así como medicamentos a base de plantas y complementarios.

  • Si alguna vez ha tenido una reacción alérgica a un medicamento.

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How to take colestipol

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about colestipol and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take the sachets exactly as your doctor tells you to. It is usual to be prescribed one sachet to take once or twice each day to begin with. Depending upon your symptoms, your doctor may slowly increase the number of sachets until you are taking up to six sachets daily.

  • The granules from each sachet should be added to at least 100 ml of water. If you prefer, you can also mix colestipol with skimmed milk, soup, fruit juice, yoghurt or fruit smoothies. The granules do not dissolve well and can have a 'bitty' texture. You will notice this less if you mix the granules with soft foods rather than thin liquids, or alternatively if you prepare your dose a little in advance and allow it to stand for a while. Do not take the granules dry or without mixing them into about 100 ml of drink/food first. Colestipol sachets are also available pre-flavoured with orange and vanilla and with an artificial sweetener in a brand called Colestid® Orange.

  • If you forget to take a dose, take it as soon as you remember. Try to take the correct number of sachets each day, but do not take two doses together to make up for a missed dose.

Aproveche al máximo su tratamiento

  • Procure acudir a las citas periódicas con su médico. Así podrá comprobar su evolución. Es posible que tenga que hacerse análisis de sangre de vez en cuando.

  • Avoid taking any other medicines at the same time as you take colestipol because it can stop the other medicines from being absorbed by your body. Either take your other medicines at least one hour before you take colestipol, or wait until 4-6 hours after taking colestipol before you take the other medicines. If you have any problems planning when to take your medicines, speak with your doctor or pharmacist for advice.

  • Treatment with colestipol is often long-term. Continue to take it unless you are advised otherwise.

  • Taking colestipol over a period of time may reduce your body's absorption of fat-soluble vitamins (vitamins A, D, E and K) and folic acid. Your doctor may advise you to take a supplement containing these vitamins.

  • Your doctor may give you advice about lifestyle changes that could help you get the most out of your treatment. This may include reducing the amount of salt in your diet, stopping smoking, losing weight, reducing the amount of alcohol you drink, and taking regular exercise. Following this advice will help you to reduce your risk of developing heart and blood vessel disease in the future.

  • Si va a someterse a una operación o a un tratamiento dental, comunique a la persona que lleve a cabo el tratamiento qué medicamentos está tomando.

  • If you buy any medicines 'over the counter', check with a pharmacist that they are suitable for you to take.

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Can colestipol cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with colestipol. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common colestipol side-effects (these affect more than 1 in 10 people)

¿Qué puedo hacer si me ocurre esto?

Estreñimiento

Intenta seguir una dieta equilibrada y beber varios vasos de agua al día. Si resulta molesto, hable con su médico.

Abdominal (tummy) pain or discomfort

Comidas sencillas: evite los alimentos ricos o picantes.

Migraine, headache

Bebe mucha agua y pide a un farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza persisten, informe a su médico.

Common colestipol side-effects (these affect fewer than 1 in 10 people)

¿Qué puedo hacer si me ocurre esto?

Feeling sick (nausea) or being sick (vomiting), indigestion, bloated feeling, wind (flatulence)

Comidas sencillas: evite los alimentos ricos o picantes.

Bleeding haemorrhoids (piles), blood in your stools

This may be related to constipation. If you notice any blood in your stools you should let your doctor know straightaway

Diarrea

Drink plenty of water to replace the fluids lost

Joint or muscle aches and pains, back pain

Ask a pharmacist to recommend a suitable painkiller. If the pain continues, let your doctor know

Erupción cutánea

Ask a pharmacist to recommend a suitable antihistamine. If the problem continues, let your doctor know

Tiredness (fatigue)

If this becomes a problem, let your doctor know

If you experience any other symptoms which you think may be due to your medicine, speak with your doctor or pharmacist for further advice.

How to store colestipol

  • Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.

  • Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.

Información importante sobre todos los medicamentos

Información importante sobre todos los medicamentos

No tome nunca más de la dosis prescrita. Si sospecha que usted u otra persona ha tomado una sobredosis de este medicamento, acuda al servicio de urgencias de su hospital. Llévese el envase, aunque esté vacío.

Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.

No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.

Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.

MHRA - Notificación de reacciones adversas

Notifique a la Agencia Reguladora de Medicamentos y Productos Sanitarios las sospechas de efectos secundarios de medicamentos, vacunas, cigarrillos electrónicos, incidentes con productos sanitarios o productos defectuosos o falsificados para garantizar un uso seguro y eficaz.

Lecturas complementarias y referencias

Historia del artículo

La información de esta página ha sido redactada y revisada por médicos cualificados.

  • Fecha de la próxima revisión: 9 de enero de 2027
  • 10 Ene 2024 | Última versión

    Última actualización

    Michael Stewart, MRPharmS

    Revisado por expertos

    Sid Dajani
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