Tabletas de Edoxabán
Lixiana
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 23 Oct 2022
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You will have been prescribed edoxaban either to treat a harmful clot that has formed in a blood vessel, or to prevent one from forming.
Take one dose each day.
The most common side-effects are bleeding (such as nosebleeds), itchy skin rash, and feeling sick (nausea).
De un vistazo
Edoxaban is a medicine that helps prevent your blood from clotting too quickly.
It is used to treat and prevent harmful blood clots, for example, in deep vein thrombosis.
Take edoxaban once daily, at the same time each day, with or without food.
If you miss a dose, take it as soon as you remember, unless it is the next day.
Tell your doctor if you are pregnant, breastfeeding, or have certain medical conditions.
Common side-effects include bleeding, bruising, and feeling sick.
Seek medical help immediately for any unusual bleeding or bleeding lasting over ten minutes.
About edoxaban
Tipo de medicamento | A factor Xa inhibitor anticoagulant |
Usado para | To prevent or treat harmful blood clots |
También llamado | Lixiana® |
Disponible como | Comprimidos |
Edoxaban works by preventing your blood from clotting as quickly or as effectively as normal. It does this by blocking a substance in your blood, called 'factor Xa', which is involved in the development of blood clots.
Sometimes, harmful blood clots can form in the blood vessels of your legs, lungs, brain or heart, and cause a blockage. This is more likely to happen if you have had surgery, or if you have a fast irregular heartbeat. For many years, a medicine called warfarin has been commonly used to treat blood clots like these and also to help protect against them. However, people who take warfarin need to have regular blood tests to measure how quickly their blood clots. This often means that the dose of warfarin can change quite frequently. Edoxaban works in a slightly different way to warfarin, so people who take edoxaban do not need to have regular blood tests.
Edoxaban is prescribed to treat blood clots causing deep vein thrombosis and pulmonary embolism. You may also be prescribed edoxaban to help protect against recurrent blood clots, or if you have a certain type of irregular fast heartbeat known as atrial fibrillation.
Before taking edoxaban
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking edoxaban it is important that your doctor knows:
Si estás embarazada o amamantando.
If you have any medical problems that increase your risk of bleeding, or if you have recently had surgery.
Si tienes presión arterial alta (hipertensión).
Si tienes algún problema con el funcionamiento de tu hígado, o con el funcionamiento de tus riñones.
If you have a problem with the blood vessels in your eyes, known as vascular retinopathy.
If you have been told you have a condition called antiphospholipid syndrome.
Si alguna vez has tenido una reacción alérgica a un medicamento.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
How to take edoxaban tablets
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about edoxaban and will provide you with a full list of the side-effects which you could experience from taking it.
Take edoxaban exactly as your doctor tells you to. It is taken once daily. Your doctor or pharmacist will tell you which strength of tablet is right for you as there are several strengths of edoxaban available (15 mg, 30 mg, and 60 mg). This information will also be printed on the label of the pack to remind you.
Try to take your tablet around the same time of day each day. This will help you to remember to take edoxaban regularly. Edoxaban can be taken either with or without food, but it should preferably be swallowed with a drink of water.
If you have difficulty swallowing, you can crush a Lixiana® tablet and mix it with water or apple purée immediately before taking. Take care to swallow the entire mixture.
If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, leave out the forgotten dose from the previous day and take the dose that is due as normal. Do not take two doses at the same time to make up for a missed dose.
Obteniendo el máximo de tu tratamiento
Intenta mantener tus citas regulares con tu médico. Esto es para que tu médico pueda verificar tu progreso.
The length of the course of treatment will depend upon why you are taking the tablets, but it will either be for several months, or long-term.
If you are due to have an operation or dental treatment, please tell the person carrying out the treatment that you are taking edoxaban.
If you take any medicines that you have bought without a prescription, check with a pharmacist that they are suitable to take with edoxaban. This is because some medicines, such as some painkillers, can interfere with it.
Can edoxaban tablets cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with edoxaban. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common edoxaban side-effects (estos afectan a menos de 1 de cada 10 personas) | ¿Qué puedo hacer si experimento esto? |
Bleeding (such as nosebleeds) and bruising | If it continues or becomes troublesome, let your doctor know |
Sentirse mal (náuseas) | Try taking the tablet after food |
Erupción cutánea con picazón | If it continues or becomes troublesome, let your doctor know |
Changes in some blood tests (including anaemia which could make you feel very tired) | Su médico verificará estos |
Importante: if you experience any unusual bleeding, or bleeding that continues for more than ten minutes, speak with your doctor straightaway or go to your local accident and emergency department.
Si experimenta cualquier otro síntoma que crea que puede deberse a las tabletas, hable con su médico o farmacéutico para obtener más consejos.
How to store edoxaban
Mantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Sitio web de Yellow Card.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Preguntas frecuentes
How does edoxaban reduce the risk of recurring blood clots?
Edoxaban works by blocking a substance called 'factor Xa', which is essential for blood clot formation. By preventing your blood from clotting as quickly or effectively, it helps to protect against new blood clots forming if you have a condition like deep vein thrombosis, pulmonary embolism, or atrial fibrillation.
Can I take edoxaban if I'm on other medications, including over-the-counter ones?
It's important that your doctor knows all medicines you are taking, including those bought without a prescription, as well as herbal and complementary medicines. Some medicines, particularly certain painkillers, can interfere with edoxaban, so always check with a pharmacist to ensure they are suitable to take together.
What should I do if I forget to take my edoxaban dose?
If you forget a dose, take it as soon as you remember. However, if you don't remember until the next day, you should skip the forgotten dose from the previous day and continue with your regular dose. Do not take two doses at the same time to compensate for a missed dose.
How long will I need to take edoxaban for?
The duration of your treatment with edoxaban will depend on the specific reason your doctor prescribed it. It could be for several months, or in some cases, it may be a long-term treatment.
What should I do if I experience unusual or prolonged bleeding while taking edoxaban?
If you experience any unusual bleeding, such as nosebleeds, or if any bleeding continues for more than ten minutes, it's very important to contact your doctor immediately or go to your local accident and emergency department without delay.
Lecturas adicionales y referencias
- Manufacturer's PIL, Lixiana® 15 mg, 30 mg, 60 mg film-coated tablets; Daiichi Sankyo UK Limited, The electronic Medicines Compendium. Dated November 2020.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
Sobre el autorVer biografía completa

Helen Allen, MPharm
Farmacéutico, Autor Médico
MPharm
Helen Allen se graduó como farmacéutica en 1979 y pasó 3 años como autora de los folletos de información sobre medicamentos para EMIS.
Acerca del revisor

Sid Dajani
Sultan Dajani se graduó en la Escuela de Farmacia de Londres en 1994 y se convirtió en el miembro más joven elegido para el consejo de la Sociedad Real de Farmacia desde su fundación en 1842.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Artículo también disponible en Inglés, Alemán, Español, Francés, Italiano, Portugués, Hindi, Hebreo, Árabe, y Sueco.
Próxima revisión: 21 Mar 2027
23 Oct 2022 | Última versión
19 Oct 2016 | Publicado originalmente
Escrito por:
Helen Allen, MPharm

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