Tadalafil for pulmonary hypertension
Adcirca, Talmanco
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSLast updated 7 Nov 2022
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When you collect your prescriptions, check that you have been given the same brand of tablets as before. If the appearance is not the same as usual, speak with your doctor or pharmacist.
The usual dose is 40 mg daily (taken as two 20 mg tablets).
The most common side-effects are headache, flushing, nasal congestion, stomach upset, and muscle aches and pains.
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About tadalafil for pulmonary hypertension
Tipo de medicamento | Vasodilator antihypertensive medicine |
Usado para | Pulmonary hypertension in adults |
También llamado | Adcirca®; Talmanco® |
Disponible como | Comprimidos |
Primario pulmonary hypertension is a rare condition where there is too high a blood pressure in the blood vessels that supply your lungs from your heart.
Tadalafil relaxes the muscle cells in the walls of the blood vessels to your lungs, allowing them to become wider (dilated). This reduces the pressure in these blood vessels and allows blood to flow more easily through them. In turn, this increases the supply of blood to your lungs and improves your ability to do physical activities. It will be prescribed for you by a specialist doctor.
Tadalafil can also be prescribed for men with two completely different conditions - please see the separate medicine leaflet called Tadalafil para la disfunción eréctil o próstata agrandada if you have been prescribed tadalafil tablets for either of these reasons.
Before taking tadalafil
Volver al contenidoSome medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking tadalafil it is important that your doctor knows:
Si estás embarazada, intentando concebir o amamantando.
If you have any other heart problem or blood vessel condition.
If you have had an eye condition causing a loss of vision.
If you have problems with the way your liver works, or if you have problems with the way your kidneys work.
If you have recently had a heart attack.
If you have any disease, injury or deformity of your penis.
If you have sickle cell disease.
If you have ever had bone marrow cancer or leukaemia.
If you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines, and recreational drugs.
Si alguna vez has tenido una reacción alérgica a un medicamento.
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How to take tadalafil
Volver al contenidoBefore you take tadalafil, read the manufacturer's printed information leaflet from inside your pack. It will give you more information about the tablets and will provide you with a full list of the side-effects which you could experience from taking them.
Take the tablets exactly as your doctor tells you to. The usual dose is two 20 mg tablets taken together, once daily.
Unless your doctor tells you otherwise, you can generally take tadalafil at a time of day that suits you. You should, however, try to take your doses at the same time of day, each day.
You can take tadalafil either with or without food. Swallow the tablets with a drink of water.
If you forget to take a dose, take it as soon as you remember as long as it is still within eight hours of the time you should have taken it. If when you remember, it is more than eight hours later, leave out the missed dose. Do not take two doses together to make up for a forgotten dose.
Obteniendo el máximo de tu tratamiento
Volver al contenidoIt is recommended that you do not drink grapefruit juice with tadalafil. This is because there is a chemical in grapefruit juice which may increase the amount of tadalafil in your bloodstream. This could make side-effects more likely.
Intenta mantener tus citas regulares con tu médico. Esto es para que tu médico pueda verificar tu progreso.
If you are due to have an operation or some other medical treatment, it is important that you tell the person carrying out the treatment that you are taking tadalafil.
Each time you collect a new supply of tablets from the pharmacy, make sure it looks to be the same as you have had before. If you are unsure, ask your pharmacist to check for you.
Si compras algún medicamento, consulta con un farmacéutico que sean adecuados para tomar con tus otros medicamentos.
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Can tadalafil cause problems?
Volver al contenidoAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with tadalafil. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common tadalafil side-effects (estos afectan a más de 1 de cada 10 personas) | ¿Qué puedo hacer si experimento esto? |
Headache, muscle aches and pains | Ask your pharmacist to recommend a suitable painkiller. If the aches continue, let your doctor know |
Facial flushing, nose or throat symptoms | If troublesome, speak with your doctor for advice |
Feeling sick (nausea) or being sick (vomiting), indigestion, tummy (abdominal) discomfort | Mantente en comidas simples - evita alimentos grasos o picantes |
Common tadalafil side-effects (estos afectan a menos de 1 de cada 10 personas) | ¿Qué puedo hacer si experimento esto? |
Feeling faint or dizzy, blurred vision | Do not drive and do not use tools or machines until your reactions/vision have returned to normal. If the problem with your eyesight starts suddenly, speak with your doctor |
Nosebleeds, the feeling of having a 'thumping heart' (palpitations), increased menstrual bleeding | If any become troublesome, speak with your doctor for advice |
Importante: if you experience any of the following, contact a doctor for medical attention straightaway:
An allergic-type reaction such as a rash or swelling around your face.
Dolores en el pecho
A sudden loss of vision or hearing
An erection lasting for more than four hours.
Si experimenta cualquier otro síntoma que crea que puede deberse a las tabletas, hable con su médico o farmacéutico para obtener más consejos.
How to store tadalafil
Volver al contenidoMantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Volver al contenidoInformación importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Yellow Card website.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Lecturas adicionales y referencias
- Manufacturer's PIL, Adcirca® 20 mg film-coated tablets; Eli Lilly and Company Limited, The electronic Medicines Compendium. Dated January 2021.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
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Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Next review due: 6 May 2027
7 Nov 2022 | Última versión
9 Jul 2013 | Publicado originalmente
Escrito por:
Helen Allen, MPharm

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