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Tabletas de Quinapril

Quinapril is generally well tolerated but if you develop a troublesome cough, you must let your doctor know.

The first dose in particular can make you feel dizzy. It is best taken just before you go to sleep.

Some painkillers and indigestion remedies could interfere with quinapril. Ask your pharmacist for advice before you buy any medicines 'over the counter'.

Clinical author's note: Michael Stewart 15/11/2018: Following an MHRA update, new advice has been added to this leaflet for people also taking the blood pressure medicine hydrochlorothiazide. Hydrochlorothiazide is only available in the UK in combination with other medicines used to treat high blood pressure. It may be available on its own in other countries. For more information see the warning below in 'can this medicine cause problems?' or view the Alerta de la MHRA.


De un vistazo

  • Quinapril is a medicine used to treat high blood pressure and heart failure.

  • It works by widening blood vessels and helping to reduce excess fluid in the blood.

  • Take quinapril exactly as your doctor tells you, usually once daily.

  • Your first dose may make you feel dizzy, so consider taking it at bedtime.

  • Common side-effects include dizziness and a dry cough.

  • Stop taking quinapril and seek immediate medical help if you have swelling of your face, mouth, tongue, or throat.

About quinapril

Tipo de medicamento

Un inhibidor de la enzima convertidora de angiotensina (ECA)

Usado para

High blood pressure (hypertension); heart failure

También llamado

Accupro® (discontinued); Accupril® (USA)
Combination brand: Accuretic® (quinapril with hydrochlorothiazide)

Disponible como

Comprimidos

Quinapril belongs to a class of medicines called angiotensin-converting enzyme inhibitors, or ACE inhibitors. You may have been prescribed it to reduce presión arterial alta (hipertensión), or to treat insuficiencia cardíaca. Your doctor will tell you why it has been prescribed for you.

ACE inhibitors like quinapril prevent your body from creating a hormone known as angiotensin II. They do this by blocking (inhibiting) a chemical called angiotensin-converting enzyme. They widen your blood vessels and help to reduce the amount of water put back into your blood by your kidneys.

These actions help to decrease blood pressure. Although people with high blood pressure often do not feel unwell, if left untreated, high blood pressure can harm the heart and damage blood vessels, leading to a heart attack or stroke.

Heart failure is a condition in which your heart does not work as well as it should. Because of this, there may be too much circulating fluid in your blood vessels. Quinapril helps to reduce this. It also appears to have a protective effect on the heart.

You may be prescribed quinapril on its own, or alongside other medicines to help your condition. The brand of quinapril called Accuretic® also contains a medicine called hydrochlorothiazide. This brand can be prescribed for people with high blood pressure. Combination brands like this help to reduce the total number of tablets you need to take each day.

Before taking quinapril

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking quinapril it is important that your doctor knows:

  • Si estás embarazada o amamantando.

  • If you have problems with the way your kidneys work, or any problems with the way your liver works.

  • Si te falta líquido en el cuerpo (deshidratado) - por ejemplo, si has tenido diarrea o vómitos recientemente.

  • Si le han dicho que tiene una acumulación de depósitos grasos en las paredes de sus arterias, una condición llamada aterosclerosis.

  • Si tienes un tipo particular de mala circulación llamado enfermedad arterial periférica.

  • If you have collagen vascular disease. This includes conditions such as systemic lupus erythematosus (SLE) and scleroderma.

  • If you have been told you have a problem with the way your heart pumps blood

  • If you have been told you have heart muscle disease (cardiomyopathy), problems with the way your heart pumps blood, or narrowing of the main blood vessel from your heart (aortic stenosis).

  • If you have been told you have a low level of sodium in your blood.

  • Si alguna vez ha tenido una reacción en la que su cara, lengua o garganta se hinchan (angioedema).

  • Si estás recibiendo tratamiento de desensibilización para protegerte contra las picaduras de abejas y avispas.

  • Si estás recibiendo tratamiento de diálisis, o tratamiento para eliminar el colesterol de tu sangre mediante una máquina (aféresis de LDL).

  • Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.

  • If you have ever had an allergic or unusual reaction to any other ACE inhibitor (such as lisinopril, ramipril or enalapril), or to any other medicine.

How to take quinapril

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about quinapril and will provide you with a full list of side-effects which you may experience from taking it.

  • Take the tablets exactly as your doctor tells you to. Quinapril is usually taken once daily, but it can also be prescribed as a twice-daily dose. Your dose will be printed on the label of the pack of tablets to remind you about what the doctor said to you.

  • Your doctor is likely to advise you to take your very first dose at bedtime. This is because the first dose can make you feel dizzy.

  • After the first dose, you can take quinapril at a time of day you find easy to remember, but try to take it at the same times of day each day. This will help you to remember to take your doses regularly. You can take quinapril tablets either with or without food. Swallow the tablet with a drink of water.

  • Si olvida tomar una dosis, tómela tan pronto como lo recuerde (a menos que esté casi la hora de su próxima dosis, en cuyo caso omita la dosis olvidada y tome la siguiente como de costumbre). No tome dos dosis juntas para compensar una dosis olvidada.

Obteniendo el máximo de tu tratamiento

  • Try to keep your regular appointments with your doctor. This is so your progress can be monitored. Your doctor may want you to have some blood tests from time to time to check that your kidneys are working well.

  • Each time you collect a prescription, check to make sure the tablets look the same as you have had before. This is because there are several strengths of tablet. If you have any questions about your tablets, please ask your pharmacist for advice.

  • Es muy importante que sigas cualquier consejo dietético y de estilo de vida que te dé tu médico. Esto puede incluir consejos sobre llevar una dieta saludable, no fumar y hacer ejercicio regularmente.

  • If you buy any medicines, check with a pharmacist that they are suitable to take with quinapril. This is because some medicines (such as anti-inflammatory painkillers and indigestion remedies) could interfere with your treatment.

  • It is likely that your doctor will advise that you do not use salt substitutes while you are taking quinapril. These products have a high content of potassium which could be harmful for you.

  • If you drink alcohol, ask your doctor for advice about drinking alcohol while you are on quinapril. Alcoholic drinks can make you feel light-headed or dizzy, and they may not be advisable for you.

  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking quinapril tablets. This is because some anaesthetics could cause your blood pressure to drop too low.

  • Treatment with quinapril is usually long-term unless you experience an adverse effect. Continue to take the tablets unless you are advised otherwise.

Can quinapril cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with quinapril. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common quinapril side-effects (these affect fewer than 1 in 10 people)

¿Qué puedo hacer si experimento esto?

Feeling light-headed or dizzy, especially when standing up

Getting up more slowly should help. If you begin to feel

dizzy, lie down so that you do not faint, then sit for a few moments before standing. If this continues beyond the first few days, speak with your doctor. Do not drive and do not use tools or machines while you feel dizzy

Tos seca e irritante

Si esto continúa, hable con su médico, ya que una medicina alternativa podría ser mejor para usted

Dolor de cabeza, otros dolores y molestias

Pídale a su farmacéutico que le recomiende un analgésico adecuado

Sentirse enfermo (náuseas) o estar enfermo (vómitos), indigestión, dolor de estómago (abdominal), diarrea

Stick to simple foods - avoid rich and spicy meals

Throat infections, runny nose, tingling feelings in your hands or toes, problems sleeping or feeling tired

Hable con su médico si alguno de estos se vuelve problemático

Importante: if you experience any of the following rare but serious symptoms, stop taking quinapril and contact your doctor for advice straightaway:

  • Cualquier dificultad para respirar, o hinchazón de su cara, boca, lengua o garganta. Estos son signos de una reacción alérgica.

  • Any yellowing of your skin or whites of your eyes. These may be signs of jaundice which is a rare side-effect.

  • Una erupción cutánea severa.

If you are also taking hydrochlorothiazide in combination with this medicine:

  • Los estudios han sugerido que tomar dosis más altas de hidroclorotiazida durante largos períodos de tiempo puede aumentar el riesgo de ciertos tipos de cáncer de piel.

  • Informe a su médico si alguna vez ha sido tratado por cáncer de piel.

  • Informe a su médico sobre cualquier lunar nuevo o cambiado, o marcas preocupantes en su piel.

  • Use a sunscreen in strong sunlight. Do not use sunbeds.

Si experimenta cualquier otro síntoma que crea que puede deberse a las tabletas, hable con su médico o farmacéutico para obtener más consejos.

How to store quinapril

  • Mantenga todos los medicamentos fuera del alcance y la vista de los niños.

  • Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.

Información importante sobre todos los medicamentos

Información importante sobre todos los medicamentos

Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.

Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.

No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.

Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.

Informar efectos secundarios de un medicamento o vacuna

Si experimenta efectos secundarios, puede reportarlos en línea a través de Sitio web de Yellow Card.

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¿Inseguro sobre mezclar medicamentos?

Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.

Preguntas frecuentes

What is the significance of the brand name Accupro being discontinued, and does this affect current quinapril users?

The article notes that Accupro is a discontinued brand name for quinapril. This information primarily serves to clarify that while the brand may no longer be available, the active medication, quinapril, is still in use and prescribed under different names or as a generic. It doesn't affect the availability or efficacy of quinapril for current users, who would receive it under its current brand (Accupril in the USA) or as a generic.

How does quinapril specifically protect the heart in individuals with heart failure?

In cases of heart failure, where the heart isn't working as efficiently as it should, quinapril helps by reducing the amount of circulating fluid in the blood vessels. Beyond this, the article states that quinapril also 'appears to have a protective effect on the heart,' contributing to better heart function in this condition.

What are collagen vascular diseases, and why is it important for my doctor to know if I have one before prescribing quinapril?

Collagen vascular diseases are a group of conditions that affect the body's connective tissues and can include diseases like systemic lupus erythematosus (SLE) and scleroderma. It's crucial for your doctor to be aware if you have such a condition because these illnesses can affect various organs, and quinapril's actions or potential side effects might interact in specific ways that require extra medical care or an alternative treatment.

What should I do if I am prescribed quinapril and also have a low level of sodium in my blood?

If you have a low level of sodium in your blood, it is important to inform your doctor before starting quinapril. The article highlights this as a condition requiring your doctor's awareness, suggesting that it might influence the suitability of quinapril for you or necessitate extra monitoring and care during your treatment.

If I am undergoing desensitisation treatment for bee and wasp stings, why do I need to inform my doctor before taking quinapril?

It is important to tell your doctor if you are having desensitisation treatment to protect against bee and wasp stings. The article indicates that this is a specific circumstance where your doctor needs to be aware of your medical history before prescribing quinapril, suggesting potential interactions or considerations during your treatment with both quinapril and the desensitisation therapy.

Can taking quinapril affect cholesterol-lowering treatments like LDL apheresis?

Yes, if you are undergoing treatment to remove cholesterol from your blood by a machine, known as LDL apheresis, it is important to inform your doctor. The article states this as a condition your doctor needs to know about before you start quinapril, suggesting potential interactions or requiring extra care during combined treatments.

How can I tell if a cough I'm experiencing is a common side effect of quinapril or something more serious?

A dry, irritating cough is listed as a common side effect of quinapril, affecting fewer than 1 in 10 people. If you develop a cough that continues or becomes troublesome, the article advises speaking with your doctor, as an alternative medicine might be more suitable for you. This distinguishes it from more serious reactions and offers a clear course of action.

Why is it important to check the appearance of my quinapril tablets each time I get a new prescription?

You should check the appearance of your quinapril tablets with each new prescription because there are several strengths of the tablet available. The article advises doing this to ensure you have received the correct dosage. If you notice any differences or have questions, you should ask your pharmacist for advice.

Lecturas adicionales y referencias

Sobre el autorVer biografía completa

Imagen del autor

Michael Stewart, MRPharmS

Gerente de Revisión de Folletos de Medicamentos – Contratista, Farmacéutico

BPharm (Hons), MRPharmS

Michael es un farmacéutico comunitario que ejerce en Midlands y South Yorkshire con más de 20 años de experiencia asesorando sobre medicamentos y condiciones médicas. Tiene una sólida formación en capacitación en atención médica, habiendo producido e impartido cursos de formación para equipos de farmacia y personal de entornos de atención residencial, incluidas enfermeras. También ha contribuido a juntas asesoras de farmacia para la gestión de condiciones de baja gravedad en la comunidad.

Acerca del revisor

Imagen del autor

Sid Dajani

Sultan Dajani se graduó en la Escuela de Farmacia de Londres en 1994 y se convirtió en el miembro más joven elegido para el consejo de la Sociedad Real de Farmacia desde su fundación en 1842.

Historial del artículo

La información en esta página está escrita y revisada por pares por clínicos calificados.

  • Próxima revisión: 15 de febrero de 2028
  • 15 Feb 2025 | Última versión

    Última actualización por

    Michael Stewart, MRPharmS

    Revisado por pares por

    Sid Dajani
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