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Irbesartan - an angiotensin receptor blocker

Aprovel, Ifirmasta

Take irbesartan once each day. You can take the tablets before or after meals.

Side-effects are usually mild. They include feeling dizzy and mild stomach upset.

Keep your regular appointments with your doctor to have your blood pressure measured.

Some painkillers interfere with irbesartan, so ask a pharmacist for advice before you buy any medicines.

Clinical author's note: Michael Stewart 15/11/2018: following an MHRA update, new advice has been added to this leaflet for people also taking the blood pressure medicine hydrochlorothiazide. Hydrochlorothiazide is only available in the UK in combination with other blood pressure medicines such as irbesartan. It may be available on its own in other countries. For more information see 'Getting the most from your treatment' below or view the Alerta de la MHRA.

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About irbesartan

Tipo de medicamento

An angiotensin-II receptor antagonist

Usado para

High blood pressure; to protect the kidneys in people with diabetes and high blood pressure

También llamado

Aprovel®; Ifirmasta®;
Combination brand: CoAprovel® (irbesartan with hydrochlorothiazide)

Disponible como

Comprimidos

Irbesartan is an angiotensin receptor blocker. It is also called an angiotensin-II receptor antagonist, or an AIIRA. It is used to treat presión arterial alta (hipertensión). People with high blood pressure usually do not feel unwell, but if left untreated, high blood pressure can harm the heart and damage blood vessels.

Irbesartan works by blocking the effect of a chemical called angiotensin II. Angiotensin II causes your blood vessels to narrow, so by blocking its effect, irbesartan allows your blood vessels to relax and widen. As this happens, the pressure within your blood vessels is reduced. Irbesartan also has a protective function on the kidneys of people with type 2 diabetes who have high blood pressure.

Irbesartan may be prescribed on its own to treat high blood pressure, or you may also be given other medicines to take alongside it. This is because a combination of medicines which work in different ways can often lower your blood pressure more than one medicine on its own. One brand of tablet called CoAprovel® contains hydrochlorothiazide as well as irbesartan - being prescribed a combination brand like this will help to reduce the number of tablets you need to take each day.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking irbesartan it is important that your doctor knows:

  • Si estás embarazada, intentando tener un bebé o amamantando.

  • If you have a problem with your kidneys, particularly if it is a blockage of the artery which supplies blood to your kidneys.

  • If you have diabetes mellitus.

  • If you have any problems with your heart valves or heart muscle.

  • Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.

  • Si alguna vez has tenido una reacción alérgica a un medicamento.

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  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about irbesartan and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take irbesartan once each day, exactly as your doctor tells you to. There are several different strengths of tablet available (75 mg, 150 mg and 300 mg) - your doctor will tell you which strength of tablet is right for you.

  • Try to take irbesartan at the same time of day each day. This will help you to remember to take your doses regularly.

  • Swallow the tablet with a drink of water. You can take irbesartan before or after meals.

  • If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, miss out the forgotten dose. Do not take two doses at the same time to make up for a forgotten dose.

  • Try to keep your regular appointments with your doctor. This is so your progress can be monitored and your blood pressure measured. Your doctor may want you to have some blood tests from time to time to check on your kidneys, and also on how much potassium is in your blood.

  • Each time you collect a prescription, check to make sure it is the strength of tablet that you are expecting.

  • If you buy any medicines, check with a pharmacist that they are suitable to take with irbesartan. This is because some anti-inflammatory painkillers (such as aspirin and ibuprofen) may interfere with the way it works, and also may increase the risk of side-effects.

  • It is very important that you follow any dietary and lifestyle advice that you may have been given by your doctor, such as eating a healthy diet, not smoking, and taking regular exercise.

  • If you drink alcohol, ask your doctor for advice. Your doctor may recommend that you do not drink alcohol while you are on irbesartan because it will increase the risk of side-effects, such as feeling dizzy or faint.

  • Try to avoid salt substitutes which contain potassium. This is because the substitutes will increase the amount of potassium in your blood and this can cause problems.

  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking irbesartan. This is because your blood pressure may drop too low if you are given some anaesthetics.

  • Treatment with irbesartan is usually long-term unless you experience an adverse effect. Continue to take the tablets regularly, unless you are advised otherwise by your doctor.

Si también está tomando hidroclorotiazida en combinación con este medicamento

  • Los estudios han sugerido que tomar dosis más altas de hidroclorotiazida durante largos períodos de tiempo puede aumentar el riesgo de ciertos tipos de cáncer de piel.

  • Informe a su médico si alguna vez ha sido tratado por cáncer de piel.

  • Informe a su médico sobre cualquier lunar nuevo o cambiado, o marcas preocupantes en su piel.

  • Use a sunscreen in strong sunlight. Do not use sunbeds.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with irbesartan. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common irbesartan side-effects (these affect fewer than 1 in 10 people)

¿Qué puedo hacer si experimento esto?

Feeling dizzy, tired, or light-headed

If any of these become troublesome, discuss them with your doctor. Do not drive and do not use tools or machines while affected

Sentirse mal (náuseas) o estar enfermo (vómitos)

Stick to simple meals - avoid rich and spicy foods

Muscle and joint pain

Ask your pharmacist to recommend a suitable painkiller. If the pain continues, speak with your doctor

Cambios en algunos análisis de sangre

Su médico verificará estos

Importante: irbesartan has been associated with an allergic-type reaction in a few people. Although this occurs only rarely, if you get any swelling of your mouth or face, speak with your doctor or go to your local accident and emergency department straightaway.

Si experimenta cualquier otro síntoma que crea que puede deberse a las tabletas, hable con su médico o farmacéutico para obtener más consejos.

  • Mantenga todos los medicamentos fuera del alcance y la vista de los niños.

  • Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.

Información importante sobre todos los medicamentos

Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.

Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.

No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.

Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.

MHRA - Reporte de reacciones adversas

Informe los efectos secundarios sospechosos de medicamentos, vacunas, cigarrillos electrónicos, incidentes con dispositivos médicos, productos defectuosos o falsificados (falsos) a la Agencia Reguladora de Medicamentos y Productos Sanitarios para garantizar un uso seguro y efectivo.

verificador de síntomas

¿Inseguro sobre mezclar medicamentos?

Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.

Lecturas adicionales y referencias

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About the author

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

Sid Dajani

Historial del artículo

La información en esta página está escrita y revisada por pares por clínicos calificados.

  • Próxima revisión: 8 de noviembre de 2026
  • 9 Nov 2023 | Última versión

    Última actualización por

    Michael Stewart, MRPharmS

    Revisado por pares por

    Sid Dajani
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