Irbesartan - an angiotensin receptor blocker
Aprovel, Ifirmasta
Revisado por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 9 Nov 2023
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Take irbesartan once each day. You can take the tablets before or after meals.
Side-effects are usually mild. They include feeling dizzy and mild stomach upset.
Acuda regularmente al médico para que le mida la tensión arterial.
Some painkillers interfere with irbesartan, so ask a pharmacist for advice before you buy any medicines.
Clinical author's note: Michael Stewart 15/11/2018: following an MHRA update, new advice has been added to this leaflet for people also taking the blood pressure medicine hydrochlorothiazide. Hydrochlorothiazide is only available in the UK in combination with other blood pressure medicines such as irbesartan. It may be available on its own in other countries. For more information see 'Getting the most from your treatment' below or view the MHRA Alert.
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About irbesartan
Tipo de medicamento | Un antagonista del receptor de angiotensina-II |
Utilizado para | High blood pressure; to protect the kidneys in people with diabetes and high blood pressure |
También llamado | Aprovel®; Ifirmasta®; |
Disponible como | Tabletas |
Irbesartan is an angiotensin receptor blocker. It is also called an angiotensin-II receptor antagonist, or an AIIRA. It is used to treat high blood pressure (hypertension). People with high blood pressure usually do not feel unwell, but if left untreated, high blood pressure can harm the heart and damage blood vessels.
Irbesartan works by blocking the effect of a chemical called angiotensin II. Angiotensin II causes your blood vessels to narrow, so by blocking its effect, irbesartan allows your blood vessels to relax and widen. As this happens, the pressure within your blood vessels is reduced. Irbesartan also has a protective function on the kidneys of people with type 2 diabetes who have high blood pressure.
Irbesartan may be prescribed on its own to treat high blood pressure, or you may also be given other medicines to take alongside it. This is because a combination of medicines which work in different ways can often lower your blood pressure more than one medicine on its own. One brand of tablet called CoAprovel® contains hydrochlorothiazide as well as irbesartan - being prescribed a combination brand like this will help to reduce the number of tablets you need to take each day.
Before taking irbesartan
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking irbesartan it is important that your doctor knows:
Si está embarazada, esperando un bebé o en período de lactancia.
Si tiene algún problema renal, sobre todo si se trata de una obstrucción de la arteria que suministra sangre a los riñones.
If you have diabetes mellitus.
Si tiene algún problema en las válvulas o el músculo cardíacos.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que pueda adquirirse sin receta, así como medicamentos a base de plantas y complementarios.
Si alguna vez ha tenido una reacción alérgica a un medicamento.
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How to take irbesartan
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about irbesartan and will provide you with a full list of the side-effects which you may experience from taking it.
Take irbesartan once each day, exactly as your doctor tells you to. There are several different strengths of tablet available (75 mg, 150 mg and 300 mg) - your doctor will tell you which strength of tablet is right for you.
Try to take irbesartan at the same time of day each day. This will help you to remember to take your doses regularly.
Swallow the tablet with a drink of water. You can take irbesartan before or after meals.
Si olvida tomar una dosis, tómela en cuanto se acuerde. Si no se acuerda hasta el día siguiente, omita la dosis olvidada. No tome dos dosis al mismo tiempo para compensar la dosis olvidada.
Aproveche al máximo su tratamiento
Try to keep your regular appointments with your doctor. This is so your progress can be monitored and your blood pressure measured. Your doctor may want you to have some blood tests from time to time to check on your kidneys, and also on how much potassium is in your blood.
Each time you collect a prescription, check to make sure it is the strength of tablet that you are expecting.
If you buy any medicines, check with a pharmacist that they are suitable to take with irbesartan. This is because some anti-inflammatory painkillers (such as aspirin and ibuprofen) may interfere with the way it works, and also may increase the risk of side-effects.
Es muy importante que siga los consejos dietéticos y de estilo de vida que le haya dado su médico, como seguir una dieta sana, no fumar y hacer ejercicio con regularidad.
If you drink alcohol, ask your doctor for advice. Your doctor may recommend that you do not drink alcohol while you are on irbesartan because it will increase the risk of side-effects, such as feeling dizzy or faint.
Intente evitar los sustitutos de la sal que contengan potasio. Los sustitutos aumentan la cantidad de potasio en la sangre y pueden causar problemas.
If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking irbesartan. This is because your blood pressure may drop too low if you are given some anaesthetics.
Treatment with irbesartan is usually long-term unless you experience an adverse effect. Continue to take the tablets regularly, unless you are advised otherwise by your doctor.
Si también está tomando hidroclorotiazida en combinación con este medicamento
Los estudios han sugerido que tomar dosis más altas de hidroclorotiazida durante periodos prolongados puede aumentar el riesgo de padecer ciertos cánceres de piel.
Informe a su médico si alguna vez ha recibido tratamiento para el cáncer de piel.
Informe a su médico de cualquier lunar nuevo o modificado o de cualquier marca preocupante en su piel.
Utilice un protector solar cuando la luz solar sea intensa. No utilice camas solares.
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Can irbesartan cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with irbesartan. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common irbesartan side-effects (these affect fewer than 1 in 10 people) | ¿Qué puedo hacer si me ocurre esto? |
Feeling dizzy, tired, or light-headed | If any of these become troublesome, discuss them with your doctor. Do not drive and do not use tools or machines while affected |
Sentirse mal (náuseas) o estar enfermo (vómitos) | Comidas sencillas: evite las comidas ricas y picantes. |
Muscle and joint pain | Ask your pharmacist to recommend a suitable painkiller. If the pain continues, speak with your doctor |
Cambios en algunos análisis de sangre | Su médico comprobará |
Important: irbesartan has been associated with an allergic-type reaction in a few people. Although this occurs only rarely, if you get any swelling of your mouth or face, speak with your doctor or go to your local accident and emergency department straightaway.
Si experimenta cualquier otro síntoma que crea que puede deberse a los comprimidos, hable con su médico o farmacéutico para que le aconsejen.
How to store irbesartan
Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
No tome nunca más de la dosis prescrita. Si sospecha que usted u otra persona ha tomado una sobredosis de este medicamento, acuda al servicio de urgencias de su hospital. Llévese el envase, aunque esté vacío.
Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.
No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.
Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.
MHRA - Notificación de reacciones adversas
Notifique a la Agencia Reguladora de Medicamentos y Productos Sanitarios las sospechas de efectos secundarios de medicamentos, vacunas, cigarrillos electrónicos, incidentes con productos sanitarios o productos defectuosos o falsificados para garantizar un uso seguro y eficaz.
Lecturas complementarias y referencias
- Manufacturer's PIL, Aprovel® 150 mg Film-coated Tablets; Sanofi, The electronic Medicines Compendium. Dated October 2022.
- Medicamentos BNF completa 89ª edición; Asociación Médica Británica y Real Sociedad Farmacéutica de Gran Bretaña, Londres.
Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
Fecha prevista para la próxima revisión: 8 nov 2026
9 Nov 2023 | Última versión

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