Pravastatin tablets
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSLast updated 27 Oct 2023
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Take pravastatin once daily, in the evening.
Follow carefully any lifestyle advice you have been given such as stopping smoking, avoiding drinking too much alcohol, eating a healthy diet and taking exercise.
If you develop any unusual cramps or pains in your muscles, contact your doctor for advice as soon as possible.
At a glance
Pravastatin is a medicine that helps lower cholesterol and other fats in your blood.
It is taken once daily in the evening, with or without food.
It reduces your risk of heart and blood vessel disease.
Women taking pravastatin must use suitable contraception to avoid pregnancy.
Tell your doctor if you experience muscle aches, pains, or weakness.
You will need regular blood tests to check your cholesterol levels and liver function.
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About pravastatin
Tipo de medicamento | A lipid-regulating medicine commonly known as a statin |
Usado para | Lowering cholesterol and other lipids in the blood (including after an organ transplant); to reduce the risk of heart and blood vessel disease |
Disponible como | Comprimidos |
Lipids, or fats, are easily stored in your body and serve as a source of energy. Colesterol is a type of lipid that is made in your liver from the fatty foods that you eat. When the concentration of cholesterol in your blood is too high, it is called hypercholesterolaemia. Although a high level of cholesterol will not make you feel ill, it can cause a problem if left untreated.
People with hypercholesterolaemia can develop small fatty patches called atheroma. These patches develop when excess fat is deposited on to the walls of blood vessels. Over time, these patches can make a blood vessel narrower and this is called atherosclerosis (sometimes referred to as 'hardening of the arteries'). The narrowing reduces the blood flow through the artery and increases the risk of a number of heart and blood vessel diseases, such as heart attack and stroke.
Pravastatin belongs to a group of medicines known as statins (or HMG-CoA reductase inhibitors). It reduces the amount of cholesterol and other lipids made by your body. It does this mainly by blocking the action of a certain enzyme which is needed to make cholesterol. This lowers your risk of heart and blood vessel disease. Pravastatin can also reduce the risk of heart disease in people who have an increased risk of it, even if their cholesterol levels are normal.
Before taking pravastatin
Volver al contenidoSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking pravastatin it is important that your doctor knows:
Si estás embarazada, intentando tener un bebé o amamantando.
If you have any problems with the way your liver works, or if you have ever had a disease which has affected your liver.
Si tienes una glándula tiroides hipoactiva.
If you have a problem with unexplained muscle aches or pains, or if you (or a close relative) have ever had a muscle disorder.
If you regularly drink large amounts of alcohol.
Si tienes algún problema con el funcionamiento de tus riñones.
Si alguna vez has tenido una reacción alérgica a un medicamento.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
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How to take pravastatin
Volver al contenidoBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about pravastatin and will provide you with a full list of the side-effects which you may experience from taking it.
Take pravastatin once each day, in the evening. There are several strengths of tablet available, so your doctor will tell you which strength is right for you. Swallow the tablet with a drink of water. It can be taken either before or after food.
Si olvida tomar una dosis, omita la dosis olvidada pero asegúrese de recordar tomar su próxima dosis cuando corresponda. No tome dos dosis juntas para compensar una dosis olvidada.
Obteniendo el máximo de tu tratamiento
Volver al contenidoTry to keep your regular appointments with your doctor. This is so that your doctor can check on your progress. You will need to have blood tests from time to time. These are to measure your cholesterol level and also to check that your liver has not been affected by taking pravastatin.
Your doctor will give you advice about eating a healthy diet, cutting down on the amount of alcohol you normally drink, reducing the amount of salt in your diet, stopping smoking and taking regular exercise. Following this advice will also help you to reduce your risk of developing heart and blood vessel disease.
Women taking pravastatin must avoid getting pregnant. Make sure you have discussed with your doctor which types of contraception are suitable for you and your partner.
Treatment with pravastatin is usually long-term unless you experience an adverse effect. Continue to take the tablets unless you are advised otherwise by your doctor.
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Can pravastatin cause problems?
Volver al contenidoAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with pravastatin, although these tend to be mild. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Pravastatin side-effects (these affect fewer than 1 in 100 people) | ¿Qué puedo hacer si experimento esto? |
Muscle aches, pains, weakness, or tenderness | Although this may not be anything to be concerned about, you should tell your doctor about this. This is because there is a rare but serious side-effect of pravastatin which is a severe form of muscle inflammation |
Dolor de cabeza | Bebe mucha agua y pide a tu farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza continúan, informa a tu médico |
Estreñimiento | Intenta comer una dieta equilibrada y beber mucha agua cada día |
Diarrea | Bebe mucha agua para reponer los líquidos perdidos |
Feeling sick (nausea), stomach ache, indigestion, wind (flatulence) | Mantente en comidas simples - evita alimentos ricos o picantes |
Blurred or double vision, feeling dizzy or tired | Do not drive and do not use tools or machines until the symptoms pass |
Disturbed sleep, sexual problems, itchy rash, thinning of hair, an increased need to pass urine particularly at night | Hable con su médico si alguno de estos se vuelve problemático |
Importante: pravastatin has been associated with more serious side-effects in a very few people. Although these occur only rarely, it is important that you tell your doctor straightaway if you experience any of the following symptoms:
If you develop any muscle cramps or pains, particularly if they are in your legs and you also feel unwell or have a high temperature (fever).
If you feel short of breath or develop an unexplained cough. This is because (in very rare cases), pravastatin may cause a disease called interstitial lung disease.
If you develop any allergic-type reactions, such as swelling around your mouth or face, or a skin rash.
Si experimenta cualquier otro síntoma que crea que puede deberse a las tabletas, hable con su médico o farmacéutico para obtener más consejos.
How to store pravastatin
Volver al contenidoMantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Volver al contenidoInformación importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
Si compras algún medicamento, consulta con un farmacéutico que sea seguro tomarlo junto con tus otros medicamentos.
Si vas a someterte a una operación o tratamiento dental, informa a la persona que realiza el tratamiento sobre los medicamentos que estás tomando.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Yellow Card website.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Preguntas frecuentes
Can I stop taking pravastatin if my cholesterol levels return to normal?
Treatment with pravastatin is typically long-term. You should continue to take your tablets unless your doctor advises you otherwise, even if your cholesterol levels appear to be normal, as this medicine helps to maintain them and reduce the risk of heart and blood vessel disease.
How do I know if the muscle aches I'm experiencing from pravastatin are serious?
While mild muscle aches, pains, weakness, or tenderness can be a side-effect, you should tell your doctor about them. In rare cases, pravastatin can cause a severe form of muscle inflammation. You should contact your doctor straight away if you develop any muscle cramps or pains, particularly if they are in your legs and you also feel unwell or have a high temperature.
What should I do if I accidentally take two doses of pravastatin?
If you forget to take a dose, you should skip the missed dose and take your next dose when it is due. You should not take two doses together to make up for a forgotten dose. Never take more than the prescribed dose. If you suspect an overdose, go to the accident and emergency department of your local hospital and take the medicine container with you.
Does pravastatin treat existing problems like narrowed arteries?
Pravastatin mainly works by reducing the amount of cholesterol and other lipids your body makes, which helps lower your risk of developing heart and blood vessel diseases. While it helps to manage cholesterol levels that can lead to problems like atherosclerosis, the article does not state it treats already existing narrowed arteries.
Are there any specific dietary changes I should make while taking pravastatin?
Your doctor will provide advice on eating a healthy diet as part of your treatment. This, along with cutting down on alcohol, reducing salt, stopping smoking, and regular exercise, can help further reduce your risk of heart and blood vessel disease. For common side-effects like constipation, a well-balanced diet and plenty of water are recommended.
Can I take pravastatin with other medicines bought without a prescription?
It is important that your doctor knows about all other medicines you are taking, including those available without a prescription, as well as herbal and complementary medicines. When buying any new medicines, you should always check with a pharmacist to ensure they are safe to take with pravastatin.
Lecturas adicionales y referencias
- Manufacturer's PIL, Pravastatin 10 mg, 20 mg and 40 mg tablets; Aurobindo Pharma - Milpharm Ltd, The electronic Medicines Compendium. Dated March 2023.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Próxima revisión: 26 de octubre de 2026
27 Oct 2023 | Última versión

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