Apixaban comprimidos
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Revisado por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 27 oct 2022
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You will have been prescribed apixaban either to treat a harmful clot that has formed in a blood vessel, or to prevent one from forming.
The usual dose is one tablet taken twice a day, morning and evening.
The most common side-effects are bleeding (such as nosebleeds) and anaemia.
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About apixaban
Tipo de medicamento | Un anticoagulante inhibidor del factor Xa |
Utilizado para | Para prevenir o tratar coágulos sanguíneos dañinos |
También llamado (Reino Unido y EE.UU.) | Eliquis® |
Disponible como | Tabletas |
Apixaban works by preventing your blood from clotting as quickly or as effectively as normal. It does this by blocking a substance in your blood, called 'factor Xa', which is involved in the development of blood clots.
Sometimes, harmful blood clots can form in the blood vessels of your legs, lungs, brain or heart, and cause a blockage. This is more likely to happen if you have had surgery, or if you have a fast irregular heartbeat. For many years, a medicine called warfarin has been commonly used to help protect against this. However, people who take warfarin need to have regular blood tests to measure how quickly their blood clots. This often means that the dose of warfarin can change quite frequently. Apixaban works in a slightly different way to warfarin, so people who take apixaban do not need to have regular blood tests.
Apixaban is prescribed to treat blood clots causing deep vein thrombosis and pulmonary embolism. You may also be prescribed apixaban to help protect against recurrent blood clots, or if you have a certain type of irregular fast heartbeat known as atrial fibrillation.
Before taking apixaban
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking apixaban it is important that your doctor knows:
Si está embarazada o en periodo de lactancia.
Si tiene algún problema médico que aumente el riesgo de hemorragia, o si se ha sometido recientemente a una intervención quirúrgica.
Si tiene algún problema con el funcionamiento del hígado o de los riñones.
Si le han dicho que padece una enfermedad llamada síndrome antifosfolípido.
Si alguna vez ha tenido una reacción alérgica a un medicamento.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que pueda adquirirse sin receta, así como medicamentos a base de plantas y complementarios.
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How to take apixaban tablets
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about apixaban and will provide you with a full list of the side-effects which you could experience from taking it.
Take apixaban exactly as your doctor tells you to. It is taken twice a day, preferably in the morning and the evening. Your doctor or pharmacist will tell you which strength of tablet is right for you as there are two strengths of apixaban available - 2.5 mg and 5 mg. This information will also be printed on the label of the pack to remind you.
Apixaban can be taken either with or without food. Swallow the tablet with a drink of water. If you have difficulty swallowing the tablet whole, you can crush the tablet and then mix it with 30 ml (two tablespoons) of water or apple juice, or alternatively, add it to some apple purée. Swallow the mixture as soon as it has been made up.
If you forget to take a dose at the usual time, take it as soon as you remember. Try to take the correct number of doses each day, but do not take two doses together to make up for a forgotten dose.
Aproveche al máximo su tratamiento
Intente acudir a las citas periódicas con su médico. Así podrá comprobar su evolución.
The length of the course of treatment will depend upon why you are taking the tablets, but it will either be for a few weeks, or long-term. If you have had hip or knee surgery, you will be asked to continue taking apixaban for a certain number of weeks. If you are taking it to protect you from blood clots developing (such as if you have atrial fibrillation), you will be asked to continue to take it over a longer period of time.
If you take any medicines that you have bought without a prescription, check with a pharmacist that they are suitable to take with apixaban. This is because some medicines, such as aspirin and some anti-inflammatory painkillers, can interfere with it.
If you are due to have an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking. This is because it may become necessary for you to stop taking apixaban for a day or so.
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Can apixaban tablets cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with apixaban. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common apixaban side-effects (afectan a menos de 1 de cada 10 personas) | ¿Qué puedo hacer si me ocurre esto? |
Bleeding (such as nosebleeds, bleeding gums) or bruising | If this continues or becomes troublesome, let your doctor know |
Anaemia (which could make you feel very tired) | Su médico lo comprobará |
Sensación de malestar (náuseas) | Try taking your doses with something to eat |
Important: if you experience any unusual bleeding, or bleeding that doesn't stop within ten minutes, speak with your doctor straightaway or go to your local accident and emergency department.
Si experimenta cualquier otro síntoma que crea que puede deberse a los comprimidos, hable con su médico o farmacéutico para que le aconsejen.
How to store apixaban
Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
No tome nunca más de la dosis prescrita. Si sospecha que usted u otra persona ha tomado una sobredosis de este medicamento, acuda al servicio de urgencias de su hospital. Llévese el envase, aunque esté vacío.
Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.
No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.
Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.
Informar de los efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede notificarlos en línea a través del sitio web de la Tarjeta Amarilla.
Lecturas complementarias y referencias
- Manufacturer's PIL, Eliquis® 2.5 mg film-coated tablets; Bristol-Myers Squibb-Pfizer, The electronic Medicines Compendium. Dated March 2022.
- Manufacturer's PIL, Eliquis® 5 mg film-coated tablets; Bristol-Myers Squibb-Pfizer, The electronic Medicines Compendium. Dated March 2022.
- Medicamentos BNF completa 89ª edición; Asociación Médica Británica y Real Sociedad Farmacéutica de Gran Bretaña, Londres.
Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
Fecha límite de la próxima revisión: 26 Oct 2025
27 Oct 2022 | Última versión
6 Nov 2013 | Originally published
Autores:
Helen Allen, Farmacéutica

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