Tabletas de apixabán
Eliquis
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 27 Oct 2022
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You will have been prescribed apixaban either to treat a harmful clot that has formed in a blood vessel, or to prevent one from forming.
The usual dose is one tablet taken twice a day, morning and evening.
The most common side-effects are bleeding (such as nosebleeds) and anaemia.
De un vistazo
Apixaban (Eliquis) is a medicine used to prevent or treat harmful blood clots.
It works by blocking a substance in your blood called factor Xa, which is involved in clotting.
Apixaban is usually taken twice a day, with or without food.
Unlike warfarin, apixaban does not require regular blood tests.
Tell your doctor about any medical conditions or other medicines you are taking before starting apixaban.
Seek medical advice immediately if you experience unusual or persistent bleeding.
About apixaban
Tipo de medicamento | A factor Xa inhibitor anticoagulant |
Usado para | To prevent or treat harmful blood clots |
Also called (UK and USA) | Eliquis® |
Disponible como | Comprimidos |
Apixaban works by preventing your blood from clotting as quickly or as effectively as normal. It does this by blocking a substance in your blood, called 'factor Xa', which is involved in the development of blood clots.
Sometimes, harmful blood clots can form in the blood vessels of your legs, lungs, brain or heart, and cause a blockage. This is more likely to happen if you have had surgery, or if you have a fast irregular heartbeat. For many years, a medicine called warfarina has been commonly used to help protect against this. However, people who take warfarin need to have regular blood tests to measure how quickly their blood clots. This often means that the dose of warfarin can change quite frequently. Apixaban works in a slightly different way to warfarin, so people who take apixaban do not need to have regular blood tests.
Apixaban is prescribed to treat blood clots causing deep vein thrombosis and pulmonary embolism. You may also be prescribed apixaban to help protect against recurrent blood clots, or if you have a certain type of irregular fast heartbeat known as fibrilación auricular.
Before taking apixaban
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking apixaban it is important that your doctor knows:
Si estás embarazada o amamantando.
If you have any medical problems that increase your risk of bleeding, or if you have recently had surgery.
Si tienes algún problema con el funcionamiento de tu hígado, o con el funcionamiento de tus riñones.
If you have been told you have a condition called antiphospholipid syndrome.
Si alguna vez has tenido una reacción alérgica a un medicamento.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
How to take apixaban tablets
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about apixaban and will provide you with a full list of the side-effects which you could experience from taking it.
Take apixaban exactly as your doctor tells you to. It is taken twice a day, preferably in the morning and the evening. Your doctor or pharmacist will tell you which strength of tablet is right for you as there are two strengths of apixaban available - 2.5 mg and 5 mg. This information will also be printed on the label of the pack to remind you.
Apixaban can be taken either with or without food. Swallow the tablet with a drink of water. If you have difficulty swallowing the tablet whole, you can crush the tablet and then mix it with 30 ml (two tablespoons) of water or apple juice, or alternatively, add it to some apple purée. Swallow the mixture as soon as it has been made up.
If you forget to take a dose at the usual time, take it as soon as you remember. Try to take the correct number of doses each day, but do not take two doses together to make up for a forgotten dose.
Obteniendo el máximo de tu tratamiento
Intenta mantener cualquier cita regular con tu médico. Esto es para que tu médico pueda verificar tu progreso.
The length of the course of treatment will depend upon why you are taking the tablets, but it will either be for a few weeks, or long-term. If you have had hip or knee surgery, you will be asked to continue taking apixaban for a certain number of weeks. If you are taking it to protect you from blood clots developing (such as if you have atrial fibrillation), you will be asked to continue to take it over a longer period of time.
If you take any medicines that you have bought without a prescription, check with a pharmacist that they are suitable to take with apixaban. This is because some medicines, such as aspirin and some anti-inflammatory painkillers, can interfere with it.
If you are due to have an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking. This is because it may become necessary for you to stop taking apixaban for a day or so.
Can apixaban tablets cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with apixaban. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common apixaban side-effects (estos afectan a menos de 1 de cada 10 personas) | ¿Qué puedo hacer si experimento esto? |
Bleeding (such as nosebleeds, bleeding gums) or bruising | If this continues or becomes troublesome, let your doctor know |
Anaemia (which could make you feel very tired) | Su médico verificará esto |
Sentirse mal (náuseas) | Try taking your doses with something to eat |
Importante: if you experience any unusual bleeding, or bleeding that doesn't stop within ten minutes, speak with your doctor straightaway or go to your local accident and emergency department.
Si experimenta cualquier otro síntoma que crea que puede deberse a las tabletas, hable con su médico o farmacéutico para obtener más consejos.
How to store apixaban
Mantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Sitio web de Yellow Card.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Preguntas frecuentes
What is the difference between Apixaban and Warfarin?
Apixaban and warfarin both help prevent blood clots. However, people taking warfarin need regular blood tests to monitor clotting times and adjust the dose, as it can change frequently. Apixaban works differently, so these regular blood tests are not necessary.
How long will I need to take Apixaban for?
The duration of your Apixaban treatment depends on why you are taking it. It could be for a few weeks, for example after hip or knee surgery, or it might be for a longer period, such as if you have atrial fibrillation to protect against blood clots.
Does Apixaban cause tiredness?
Yes, anaemia is a common side-effect of Apixaban, affecting fewer than 1 in 10 people, and it can make you feel very tired. Your doctor will monitor you for this.
Can I take other medicines with Apixaban?
You should check with your doctor or a pharmacist before taking any other medicines, including those you can buy without a prescription, herbal remedies, or complementary medicines. Some, like aspirin and certain anti-inflammatory painkillers, can interfere with Apixaban.
What should I do if I cannot swallow the Apixaban tablet whole?
If you have difficulty swallowing the tablet whole, you can crush it and mix it with 30 ml (two tablespoons) of water or apple juice. Alternatively, you can mix it with some apple purée. Make sure to swallow the mixture immediately after preparing it.
Lecturas adicionales y referencias
- Manufacturer's PIL, Eliquis® 2.5 mg film-coated tablets; Bristol-Myers Squibb-Pfizer, The electronic Medicines Compendium. Dated March 2022.
- Manufacturer's PIL, Eliquis® 5 mg film-coated tablets; Bristol-Myers Squibb-Pfizer, The electronic Medicines Compendium. Dated March 2022.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
Sobre el autorVer biografía completa

Helen Allen, MPharm
Farmacéutico, Autor Médico
MPharm
Helen Allen se graduó como farmacéutica en 1979 y pasó 3 años como autora de los folletos de información sobre medicamentos para EMIS.
Acerca del revisor

Sid Dajani
Sultan Dajani se graduó en la Escuela de Farmacia de Londres en 1994 y se convirtió en el miembro más joven elegido para el consejo de la Sociedad Real de Farmacia desde su fundación en 1842.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Artículo también disponible en Inglés, Alemán, Español, Francés, Italiano, Portugués, Hindi, Hebreo, Árabe, y Sueco.
Próxima revisión: 25 Mar 2027
27 Oct 2022 | Última versión
6 Nov 2013 | Publicado originalmente
Escrito por:
Helen Allen, MPharm

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