Cyclopenthiazide tablets
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSLast updated 31 Mar 2025
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Clinical author's note Michael Stewart 22/04/2019: Navidrex® and Navispare® tablets have been discontinued in the UK. At the time of review there are no branded or generic products containing cyclopenthiazide available in the UK. Cyclopenthiazide may still be available in other countries. This medicine leaflet is based on medical information available in the UK at the time of writing. Please also refer to the manufacturer's information supplied with your medicine.
Cyclopenthiazide is a 'water tablet' (a diuretic).
Es mejor tomarlo por la mañana.
Any side-effects are usually mild, but may include feeling sick or dizzy.
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About cyclopenthiazide
Tipo de medicamento | A thiazide diuretic |
Usado para | High blood pressure; fluid retention; heart failure |
También llamado | Navidrex®, Navispare® (discontinued) |
Disponible como | Comprimidos |
Cyclopenthiazide belongs to a group of medicines called diuréticos tiazídicos. A diuretic is a medicine which increases the amount of urine that you pass out from your kidneys. They are often referred to as 'water tablets'. Diuretics are a common treatment for presión arterial alta (hypertension). They are also used to clear excess fluid from your body in conditions where your body retains more than it needs. This is called edema. Cyclopenthiazide is also useful in people who have insuficiencia cardíaca. Heart failure is a condition where your heart is not functioning as well as it should.
Diuretics like cyclopenthiazide work by interfering with the transport of salt and water across certain cells in your kidneys. The effect of this is to make your kidneys pass out more urine. The removal of fluid reduces your blood pressure and helps reduce the work your heart has to do.
Cyclopenthiazide is usually given alongside other diuretics to treat high blood pressure. When it is used like this, you may be prescribed a combination tablet, such as Navispare®. This brand contains cyclopenthiazide with amiloride. Combination tablets like this help to reduce the number of tablets you need to take each day.
Before taking cyclopenthiazide
Volver al contenidoSome medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking cyclopenthiazide it is important that your doctor knows:
Si estás embarazada o amamantando.
Si tienes algún problema con el funcionamiento de tu hígado, o algún problema con el funcionamiento de tus riñones.
If you have gout, diabetes or an inflammatory condition called systemic lupus erythematosus (also called lupus, or SLE). These conditions can be made worse by medicines like cyclopenthiazide.
Si un médico le ha dicho que tiene niveles bajos de sodio o potasio en la sangre, o niveles altos de calcio en la sangre.
If you have a problem with your adrenal glands, called Enfermedad de Addison.
Si está tomando o usando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
Si alguna vez has tenido una reacción alérgica a un medicamento.
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How to take cyclopenthiazide
Volver al contenidoBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about cyclopenthiazide and will provide you with a full list of the side-effects which you may experience from taking it.
Take cyclopenthiazide tablets exactly as your doctor tells you to. The usual dose is ½-1 tablet daily. Your doctor is likely to recommend that you take your dose in the morning. This is so it works during the day and your sleep is not disturbed by you needing to get up to go to the toilet during the night.
Swallow the tablet with a drink of water. You can take it either with or without food.
If you forget to take a dose, take it as soon as you remember. However, if it is late afternoon when you remember, leave out the forgotten dose and take your next dose as usual on the following day. Do not take two doses on the same day to make up for a missed dose.
Obteniendo el máximo de tu tratamiento
Volver al contenido'Water tablets' (diuretics) like cyclopenthiazide help you to lose water. Occasionally you may lose too much and become lacking in fluid in the body (dehydrated). Let your doctor know if you feel constantly thirsty, your mouth is dry, or your skin looks and feels dry.
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. The salt balance in your bloodstream may be upset by cyclopenthiazide and your doctor may want you to have a blood test from time to time to check for this.
If you have been prescribed cyclopenthiazide for high blood pressure (hypertension), your treatment is likely to be long-term. Although many people with high blood pressure do not feel unwell, if left untreated, high blood pressure can harm your heart and damage your blood vessels. This damage may later result in a heart attack, stroke, or kidney problems, so it is important that you continue to take the tablets regularly to help reduce the risk of this. You may also be given some lifestyle and dietary advice by your doctor, such as stopping smoking, reducing the amount of salt in your diet, eating more fruit and vegetables and less saturated fat, and taking some regular exercise. Following this advice will also help to reduce the risk of damage to your heart and blood vessels.
Ask your doctor for advice before drinking alcohol while you are on cyclopenthiazide. Alcohol will add to the blood pressure-lowering effect of cyclopenthiazide which will increase the possibility of you experiencing side-effects such as dizziness.
If you buy any medicines, check with a pharmacist that they are suitable to take alongside cyclopenthiazide.
Si tienes programada una operación o cualquier tratamiento dental, informa a la persona que realizará el tratamiento sobre los medicamentos que estás tomando.
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Can cyclopenthiazide cause problems?
Volver al contenidoAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with cyclopenthiazide. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common cyclopenthiazide side-effects | ¿Qué puedo hacer si experimento esto? |
Sensación de malestar (náuseas), malestar estomacal | This is usually mild, but it may help to take cyclopenthiazide after food if you are not already doing so |
Sentirse mareado, especialmente al ponerse de pie (debido a la baja presión arterial) | Getting up more slowly should help. Do not drive and do not use tools or machines while affected |
Si experimenta cualquier otro síntoma que crea que puede deberse a las tabletas, hable con su médico o farmacéutico para obtener más consejos.
How to store cyclopenthiazide
Volver al contenidoMantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Volver al contenidoInformación importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda de inmediato al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Yellow Card website.

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Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Lecturas adicionales y referencias
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
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Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Next review due: 31 Mar 2028
31 Mar 2025 | Última versión

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