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Spironolactone

Aldactone

Spironolactone is a diuretic, also known as a 'water tablet'.

It will make you go to the toilet more often to pass urine.

The most common side-effect is a mild stomach upset. This is not usually troublesome.

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About spironolactone

Tipo de medicamento

Aldosterone antagonist diuretic, potassium-sparing diuretic

Utilizado para

Fluid retention
Heart failure
Primary hyperaldosteronism

También llamado

Aldactone®;
Combination brands: Lasilactone® (spironolactone with furosemide); Aldactide® (spironolactone with hydroflumethiazide - co-flumactone)

Disponible como

Tabletas

Spironolactone is used to treat fluid retention (oedema) caused by liver disease, kidney problems or heart failure. Oedema occurs when fluid leaks out of your blood vessels, causing swelling in the tissues of your lungs, feet or ankles. This makes you feel breathless or your legs feel puffy. Spironolactone prevents a build-up of fluid in your body by increasing the amount of urine your kidneys produce. It is also used to treat some other conditions which cause fluid retention, such as a disorder called primary hyperaldosteronism.

Spironolactone is known as a potassium-sparing diuretic. Unlike some other diuretics, it does not cause your body to lose potassium. Diuretics are sometimes referred to as 'water tablets'.

Spironolactone is often used alongside other diuretics. When it is used like this, it may be prescribed as a combination product, such as in Lasilactone® (spironolactone with furosemide) and Aldactide® (spironolactone with hydroflumethiazide). Combinations like these help to reduce the number of tablets you need to take each day.

Before taking spironolactone

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking spironolactone it is important that your doctor or pharmacist knows:

  • Si está embarazada, esperando un bebé o en período de lactancia.

  • Si tiene problemas renales.

  • If you are being treated for prostate cancer.

  • Si tiene un problema en las glándulas suprarrenales, llamado enfermedad de Addison.

  • If you have a rare inherited blood disorder, called porphyria.

  • Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que pueda adquirirse sin receta, así como medicamentos a base de plantas y complementarios.

  • Si alguna vez ha tenido una reacción alérgica a un medicamento.

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How to take spironolactone

  • Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The leaflet will give you more information about spironolactone and a full list of side-effects which you may experience from taking it.

  • Take spironolactone exactly as your doctor has told you. The usual dose varies from 25 mg to 200 mg. Depending upon which dose is right for you, you may be asked to take several tablets a day but these are generally taken at the same time.

  • Take the tablets with or just after a meal.

  • Spironolactone is commonly prescribed just once daily and you can generally take the dose at a time to suit you. However, diuretics are best taken no later than mid-afternoon. This is because you will find you may need to go to the toilet a couple of times after taking them and this could disturb your sleep if you take it late in the day.

  • If you have been prescribed more than one tablet of spironolactone a day and told to take them at different times, make sure you take your last tablet no later than 6 pm.

  • If you forget to take a dose, take it as soon as you remember. However, if it is after 6 pm in the evening, skip the missed dose and continue as usual the next day. Do not take two doses at the same time to make up for a missed dose.

Aproveche al máximo su tratamiento

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. The salt balance in your bloodstream may be upset by diuretics and your doctor will want you to have a blood test from time to time to check for this.

  • Diuretics help you to lose water, so you can breathe or move more easily. If, however, you lose too much fluid, you may become dehydrated. This will make you feel thirsty and make your skin look and feel dry. Let your doctor know if this happens, as your dose may need to be adjusted.

  • Another sign of dehydration with spironolactone is rapid weight loss after starting the tablets. Speak with your doctor if you notice this happening.

  • Because spironolactone is a potassium-conserving diuretic, you should try to avoid things with a high potassium content, such as 'salt substitutes' or low-sodium salt. This is so the level of potassium in your body does not become too high.

  • Treatment with diuretics is usually long-term, so continue to take these tablets unless you are advised otherwise by your doctor.

  • Si compra algún medicamento, compruebe con un farmacéutico que es adecuado para tomarlo con sus otros medicamentos.

  • Si va a someterse a una operación o a un tratamiento dental, comunique a la persona que lleve a cabo el tratamiento qué medicamentos está tomando.

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Can spironolactone cause problems?

Además de sus efectos útiles, la mayoría de los medicamentos pueden producir efectos secundarios no deseados, aunque no todas las personas los sufran. Estos suelen mejorar a medida que el organismo se adapta al nuevo medicamento, pero hable con su médico o farmacéutico si alguno de los siguientes efectos secundarios persiste o se vuelve molesto.

Spironolactone side-effects


¿Qué puedo hacer si me ocurre esto?

Sentirse mal (náuseas) o estar enfermo (vómitos)

Comidas sencillas: evite los alimentos ricos o picantes.

Feeling tired, dizzy, or sleepy

Si esto ocurre, no conduzca ni utilice herramientas o máquinas hasta que se sienta mejor.

Sexual problems, breast discomfort and enlargement, feeling confused, irregular periods, confusion, sweating, cramps, hair loss or unwanted hair growth, and skin rash

Si alguno de ellos le resulta molesto, hable con su médico

Si experimenta cualquier otro síntoma que considere que puede deberse a este medicamento, consulte a su médico o farmacéutico.

How to store spironolactone

  • Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.

  • Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.

Información importante sobre todos los medicamentos

Información importante sobre todos los medicamentos

Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.

Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.

No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.

Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.

Informar de los efectos secundarios de un medicamento o vacuna

Si experimenta efectos secundarios, puede notificarlos en línea a través del sitio web de la Tarjeta Amarilla.

Lecturas complementarias y referencias

Historia del artículo

La información de esta página ha sido redactada y revisada por médicos cualificados.

  • Fecha límite de la próxima revisión: 27 feb 2027
  • 30 ago 2022 | Última versión

    Última actualización

    Michael Stewart, MRPharmS

    Revisado por expertos

    Sid Dajani
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