Indapamide tablets
Natrilix SR
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSLast updated 9 Jun 2024
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Indapamide is prescribed for high blood pressure (hypertension).
Es mejor tomarlo por la mañana.
Any side-effects are usually mild. The most common are a skin rash, feeling sick (nausea), and feeling dizzy.
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About indapamide
Tipo de medicamento | An antihypertensive |
Usado para | Presión arterial alta |
También llamado | Standard-release tablets: Natrilix® Modified-release tablets: Alkapamid® XL; Cardide® SR; Lorvacs® XL; Natrilix SR® |
Disponible como | Tablets and modified-release tablets |
What is indapamide?
Volver al contenidoIndapamide is prescribed for the treatment of presión arterial alta (hipertensión). Although it belongs to a group of medicines called diuretics (which generally work by making the kidneys pass more urine out of the body), at the doses prescribed for hypertension, indapamide is considered to work by widening (dilating) blood vessels. By widening the blood vessels, it reduces the pressure inside the blood vessels and over time this leads to a lowering of high blood pressure.
Indapamide is available as standard tablets and also as modified-release tablets. Both forms of tablet are taken just once daily. The modified-release tablets have letters such as 'XL' or 'SR' after their brand name. Modified-release tablets release indapamide more slowly over the day than the standard tablets do.
Indapamide can be used as a treatment for high blood pressure on its own, or it can be prescribed in combination with other medicines which reduce blood pressure.
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Before taking indapamide
Volver al contenidoSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking indapamide it is important that your doctor knows:
Si estás embarazada o amamantando.
Si tienes algún problema con el funcionamiento de tu hígado, o algún problema con el funcionamiento de tus riñones.
If you have gout, diabetes or an inflammatory condition called systemic lupus erythematosus (also called lupus, or SLE). These conditions can be made worse by medicines like indapamide.
Si un médico le ha dicho que tiene niveles bajos de sodio o potasio en la sangre, o niveles altos de calcio en la sangre.
If you have a problem with your adrenal glands, called Enfermedad de Addison.
Si tienes un trastorno sanguíneo hereditario raro llamado porfiria.
Si está tomando o usando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
If you have ever had an allergic reaction to a medicine. It is particularly important that you tell your doctor if you have an allergy to penicillin or you have had an unusual reaction to a medicine known as a 'sulfonamide'.
How to take indapamide
Volver al contenidoBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about indapamide and will provide you with a full list of the side-effects which you may experience from taking it.
Take indapamide exactly as your doctor tells you to. The usual dose is one tablet daily. Your doctor is likely to recommend that you take the tablet in the morning.
Swallow the tablet with a drink of water. You can take it either before or after a meal.
If you have been prescribed a modified-release tablet (these have 'SR' or 'XL' after the brand name), these tablets should be swallowed whole. Do not break, crush or chew them.
If you forget to take a dose, take it as soon as you remember. However, if it is after 6 pm, you should skip the forgotten dose and take your next dose as usual on the following day. Do not take two doses on the same day to make up for a missed dose.
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Obteniendo el máximo de tu tratamiento
Volver al contenidoTreatment for high blood pressure (hypertension) is usually long-term. Although many people with high blood pressure do not feel unwell, if left untreated, high blood pressure can harm your heart and damage your blood vessels. This damage may later result in a heart attack, stroke, or kidney problems, so it is important that you continue to take these tablets regularly to help reduce the risk of this.
Try to keep your regular appointments with your doctor. This is so your doctor can monitor your blood pressure and check on your progress. Also, the salt balance in your bloodstream may be upset by indapamide and your doctor may want you to have a blood test from time to time to check for this.
You may be given some lifestyle or dietary advice by your doctor, such as stopping smoking, reducing the amount of salt in your diet and taking some regular exercise. Following this advice will also help to reduce the risk of damage to your heart and blood vessels.
Drinking alcohol while you are on indapamide may make you feel dizzy. Ask for your doctor's advice about whether you should avoid alcohol.
If you are due to have an operation or dental treatment, you should tell the person carrying out the treatment which medicines you are taking.
If you are an athlete, please be aware that indapamide may give a positive reaction in doping tests.
Side-effects of indapamide
Volver al contenidoAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with indapamide. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common indapamide side-effects (these affect fewer than 1 in 10 people) | ¿Qué puedo hacer si experimento esto? |
A rash, or an increased sensitivity to sunlight | Speak with your doctor for advice as your treatment may need to be reviewed |
A low level of potassium in your blood | Your doctor may arrange blood tests to check for this. Watch out for signs such as tiredness and muscle cramps |
Less common indapamide side-effects (these affect fewer than 1 in 100 people) | ¿Qué puedo hacer si experimento esto? |
Sentirse mal (náuseas) o vomitar (vómitos), malestar estomacal | Stick to simple foods - avoid rich or spicy meals. Try taking the tablet after a meal if you are not already doing so |
Sentirse mareado, especialmente al ponerse de pie (debido a la baja presión arterial) | Levantarse más despacio debería ayudar. No conduzca ni use herramientas o máquinas hasta que se sienta mejor |
Importante: In very rare cases 'sulfonamide' medicines have caused sudden raised pressure in the eyes leading to serious vision problems. It can happen in the first few days to weeks of starting the medicine. The risk is higher if you have had a previous allergic reaction to penicillin or to other 'sulfonamide' medicines. Seek urgent medical attention if you have sudden, severe eye pain with a red eye and reduced or blurred vision. Tell the person treating you that you are taking this medicine.
Si experimenta cualquier otro síntoma que crea que puede deberse a las tabletas, hable con su médico o farmacéutico para obtener más consejos.
How to store indapamide
Volver al contenidoMantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Volver al contenidoInformación importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. No lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
Si compras algún medicamento, consulta con un farmacéutico que sean adecuados para tomar con tus otros medicamentos.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Yellow Card website.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Lecturas adicionales y referencias
- Manufacturer's PIL, Natrilix® 2.5 mg Tablets; Servier Laboratories Limited, The electronic Medicines Compendium. Dated October 2021.
- Manufacturer's PIL, Natrilix® SR 1.5mg tablets; Servier Laboratories Ltd, The electronic Medicines Compendium. Dated October 2021.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
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Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Próxima revisión: 22 de mayo de 2027
9 Jun 2024 | Última versión

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