Tabletas de prasugrel
Efient
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 9 Ene 2023
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You will be given six 10 mg tablets to take as your first dose. After this, take one tablet daily.
The most common unwanted effect is an increased risk of bleeding. It is important that you let your doctor know if you notice any unusual or unexpected bleeding or bruising.
If you need to take any painkillers, check with your doctor or pharmacist that they are suitable for you. Some painkillers interact with prasugrel.
De un vistazo
Prasugrel is an antiplatelet medicine that helps prevent blood clots.
It is prescribed after a heart procedure to open a blocked artery or after a stent insertion.
You will usually take it alongside aspirin for up to 12 months.
Take prasugrel exactly as your doctor tells you, usually one tablet daily.
Tell your doctor if you are pregnant, breastfeeding, or have a bleeding condition.
Before any operation or dental treatment, inform the practitioner you are taking prasugrel.
Side effects can include bleeding, bruising, and nosebleeds.
About prasugrel tablets
Tipo de medicamento | Un medicamento antiplaquetario |
Usado para | To prevent clots forming in blood vessels after a procedure called percutaneous coronary intervention (to open a blocked artery in the heart or for a stent insertion) |
También llamado | Efient® |
Disponible como | Comprimidos |
In your blood there are 'sticky' cells called platelets. When you cut yourself, the platelets stick to each other (clot) to seal the wound. Sometimes platelets stick to each other inside an artery - this is called a thrombus. If a thrombus forms in a blood vessel around your heart, this reduces the flow of blood to your heart. The term acute coronary syndrome (ACS) covers a range of disorders that are caused by this underlying problem, and include ataques cardíacos and a type of chest pain known as unstable angina.
If you require a procedure to open a blocked artery in your heart because you have already had a heart attack or because you have unstable angina, you will be prescribed an antiplatelet medicine like prasugrel during the procedure.
For some people with ACS, the most appropriate treatment is to have a stent inserted into the blocked or narrowed artery to restore the flow of blood. A stent is like a wire mesh tube which gives support to the blood vessel. After a stent has been inserted, antiplatelet medicines are given routinely. These medicines reduce the stickiness of platelets, and this helps prevent the platelets from sticking to the inside of the artery and going on to form a further clot (thrombus).
Prasugrel is one of these antiplatelet medicines. Your doctor will also prescribe aspirin for you to take alongside prasugrel. Aspirina is another antiplatelet medicine.
Before taking prasugrel tablets
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking prasugrel tablets it is important that your doctor knows:
Si estás embarazada o amamantando.
Si tienes algún problema con el funcionamiento de tu hígado, o si tienes algún problema con el funcionamiento de tus riñones.
If you have ever had a stroke, or a transient ischaemic attack (sometimes called a TIA or 'mini-stroke').
If you have a condition which causes bleeding, such as a recent wound or a stomach ulcer.
If you have ever had an allergic reaction to a medicine, particularly if you have had a bad reaction to any other antiplatelet medicine (for example, clopidogrel).
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
How to take prasugrel tablets
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about prasugrel, and it will also provide you with a full list of the side-effects which you could experience from taking it.
Take the tablets exactly as your doctor tells you to. On the first day of treatment, you will be given six 10 mg tablets (60 mg) to take so that you get sufficient medicine into your bloodstream to begin with. After this, you will be prescribed one tablet to take each day. For most people, the tablets will contain 10 mg prasugrel, although depending upon your body weight you could be prescribed the lower 5 mg strength tablet.
Swallow the tablets with a drink of water - do not crush or chew the tablets as you swallow. You can take prasugrel tablets either with or without food.
Try to take your doses around the same time of day, each day. This will help you to remember to take prasugrel regularly.
If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, leave out the forgotten dose from the previous day and take the dose that is due as normal. Do not take two doses at the same time to make up for a missed dose.
Obteniendo el máximo de tu tratamiento
Try to keep all your regular appointments with your doctor. This is so your doctor can check on your progress. It is likely you will require a course of treatment with prasugrel which lasts for up to 12 months.
If you buy any medicines, check with a pharmacist that they are suitable for you to take with prasugrel tablets. Some medicines, called non-steroidal anti-inflammatory drugs (NSAIDs), can increase the risk of bleeding, so check with a pharmacist before you buy any painkillers. Also, do not take any preparations containing aspirin that have not been prescribed for you by your doctor. Several medicines for pain relief and cold relief that can be bought at retail outlets contain aspirin or ibuprofen - you should not take these, so check the label carefully before you buy.
If you are due to have an operation, before the treatment is due, tell the person carrying out the treatment that you are taking prasugrel. This is because any bleeding may take longer than normal to stop so your treatment may need to be interrupted for a short while before the operation. You should also let your dentist know that you are taking prasugrel before you receive any dental treatment.
Can prasugrel tablets cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with prasugrel. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common prasugrel side-effects (these affect fewer than 1 in 10 people) | ¿Qué puedo hacer si experimento esto? |
Bleeding, bruising, nosebleeds. Stopping bleeding could take longer than normal | Let your doctor know if you notice any unusual or unexpected bleeding or bruising |
Skin rash, feeling tired (due to anaemia) | Let your doctor know, especially if it is severe or troublesome |
Si experimenta cualquier otro síntoma que crea que puede deberse a las tabletas, hable con su médico o farmacéutico para obtener más consejos.
How to store prasugrel tablets
Mantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Sitio web de Yellow Card.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Preguntas frecuentes
What is the typical duration of prasugrel treatment?
You will likely need to take prasugrel for a course of treatment that could last for up to 12 months.
What should I do if I need to have a medical or dental procedure while taking prasugrel?
It is important to inform the person carrying out any medical treatment or your dentist that you are taking prasugrel. This is because prasugrel can cause bleeding to take longer than usual to stop, and your treatment with the medicine may need to be temporarily interrupted before some procedures.
Are there any over-the-counter medicines I should avoid while taking prasugrel?
Yes, you should avoid taking any non-steroidal anti-inflammatory drugs (NSAIDs) even if they are bought without a prescription, as these can increase the risk of bleeding. Also, do not take any preparations containing aspirin not prescribed by your doctor. Many pain relief and cold relief medicines contain either aspirin or ibuprofen, so always check the label carefully before buying them.
What should I do if I notice unusual bleeding or bruising while taking prasugrel?
If you experience any unusual or unexpected bleeding or bruising, or if bleeding takes longer than normal to stop, you should let your doctor know.
What is acute coronary syndrome (ACS) and how does prasugrel help it?
Acute coronary syndrome (ACS) refers to various heart conditions, including heart attacks and unstable angina, caused by reduced blood flow to the heart due to a clot in a blood vessel. Prasugrel is an antiplatelet medicine that reduces the 'stickiness' of platelets, helping to prevent these clots from forming or re-forming, especially after procedures like stent insertion.
Lecturas adicionales y referencias
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
- Manufacturer's PIL, Prasugrel 10mg film-coated tablets; Accord Healthcare Ltd, The electronic Medicines Compendium. Dated January 2019.
Sobre el autorVer biografía completa

Helen Allen, MPharm
Farmacéutico, Autor Médico
MPharm
Helen Allen se graduó como farmacéutica en 1979 y pasó 3 años como autora de los folletos de información sobre medicamentos para EMIS.
Acerca del revisor

Sid Dajani
Sultan Dajani se graduó en la Escuela de Farmacia de Londres en 1994 y se convirtió en el miembro más joven elegido para el consejo de la Sociedad Real de Farmacia desde su fundación en 1842.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Artículo también disponible en Inglés, Alemán, Español, Francés, Italiano, Portugués, Hindi, Hebreo, Árabe, y Sueco.
Próxima revisión: 8 Jul 2027
9 Ene 2023 | Última versión
10 Sept 2013 | Publicado originalmente
Escrito por:
Helen Allen, MPharm

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