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Moexipril - un inhibidor de la ECA

Clinical author's note 27/11/2017: Michael Stewart: Moexipril was discontinued in the UK in March 2016. At the time of review there are no branded or generic products containing moexipril available in the UK. Moexipril may still be available in other countries. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.

The first dose of moexipril may make you feel dizzy, so it is best taken just before bedtime.

Some painkillers and indigestion remedies interfere with moexipril, so ask your pharmacist for advice before you buy any medicines.

Some people taking moexipril can develop a troublesome cough. If this happens to you, let your doctor know.

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About moexipril

Tipo de medicamento

Un inhibidor de la enzima convertidora de angiotensina (IECA)

Utilizado para

Presión arterial alta (hipertensión)

También llamado

Perdix® (discontinued); Univasc® (US)

Disponible como

Tabletas

Moexipril belongs to a class of medicines called angiotensin-converting enzyme inhibitors, or ACE inhibitors. You will have been prescribed it to reduce high blood pressure (hypertension). Although people with high blood pressure usually feel well, if left untreated, high blood pressure can harm the heart and damage blood vessels, leading to a heart attack or stroke.

ACE inhibitors like moexipril prevent your body from creating a hormone known as angiotensin II. They do this by blocking (inhibiting) a chemical called angiotensin-converting enzyme. This widens your blood vessels and helps to reduce the amount of water put back into your blood by your kidneys. These actions help to lower the high blood pressure.

You may be prescribed moexipril on its own, or alongside other medicines to help your condition.

Before taking moexipril

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking moexipril it is important that your doctor knows:

  • Si está embarazada, esperando un bebé o en período de lactancia.

  • If you have problems with the way your kidneys work, or any problems with the way your liver works.

  • Si tiene falta de líquido en el organismo (deshidratación); por ejemplo, si ha tenido diarrea o ha estado enfermo recientemente.

  • Si le han dicho que tiene una acumulación de depósitos grasos en las paredes de las arterias, una enfermedad llamada aterosclerosis.

  • Si padece un tipo concreto de mala circulación denominado enfermedad arterial periférica.

  • Si padece una enfermedad vascular del colágeno, como el lupus eritematoso sistémico (LES) y la esclerodermia.

  • If you have been told you have a heart problem such as heart muscle disease (cardiomyopathy), or narrowing of the main blood vessel from your heart (aortic stenosis).

  • Si alguna vez ha tenido una reacción en la que se le hincha la cara, la lengua o la garganta (angioedema).

  • Si está en tratamiento de desensibilización para protegerse de las picaduras de abejas y avispas.

  • Si está en tratamiento de diálisis o tratamiento para eliminar el colesterol de la sangre mediante una máquina (aféresis LDL).

  • Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que pueda adquirirse sin receta, así como medicamentos a base de plantas y complementarios.

  • If you have ever had an allergic or unusual reaction to any other ACE inhibitor (such as lisinopril, ramipril or perindopril), or to any other medicine.

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How to take moexipril

  • Before you start this treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about moexipril and will provide you with a full list of side-effects which you may experience from taking it.

  • Take moexipril exactly as your doctor tells you to. You will be asked to take one dose each day.

  • Your doctor will advise you to take your very first dose at bedtime. This is because the first dose may make you feel dizzy.

  • After the first dose, you can generally take moexipril at any time of day you find easy to remember - for most people, this will be first thing in the morning. Try to take your dose at the same time each day. You should ideally take the tablet before food as this allows your body to absorb more of the medicine. Swallow the tablet with a drink of water.

  • Si olvida tomar una dosis a la hora habitual, tómela en cuanto se acuerde. Si no se acuerda hasta el día siguiente, sáltese la dosis olvidada. No tome dos dosis al mismo tiempo para compensar la dosis olvidada.

Aproveche al máximo su tratamiento

  • Intente acudir a las citas periódicas con su médico. Así podrá controlar su evolución. Es posible que su médico quiera hacerle análisis de sangre de vez en cuando para comprobar que sus riñones funcionan bien.

  • Es muy importante que siga los consejos dietéticos y de estilo de vida que le dé su médico. Esto puede incluir consejos sobre una dieta sana, no fumar y hacer ejercicio con regularidad.

  • If you buy any medicines, check with a pharmacist that they are suitable to take with moexipril. This is because some medicines (such as anti-inflammatory painkillers and indigestion remedies) may interfere with your treatment.

  • It is likely that your doctor will advise that you do not use salt substitutes while you are taking moexipril. These products have a high content of potassium which could be harmful for you.

  • If you have a bout of sickness or diarrhoea, your doctor may advise you to stop taking the tablets for a short while until you are drinking sufficient fluids again. This is to help prevent any damage to your kidneys while you are dehydrated.

  • If you drink alcohol, ask your doctor for advice about drinking alcohol while you are on moexipril. Alcoholic drinks may make you feel light-headed or dizzy, and may not be advisable for you.

  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking moexipril tablets. This is because some anaesthetics may cause your blood pressure to drop too far.

  • Treatment with moexipril is usually long-term unless you experience an adverse effect. Continue to take the tablets unless you are advised otherwise.

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Can moexipril cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with moexipril. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common moexipril side-effects (these affect fewer than 1 in 10 people)

¿Qué puedo hacer si me ocurre esto?

Tos seca e irritante

If this continues, speak with your doctor as an alternative medicine may be better for you

Feeling dizzy, especially when standing up

Getting up more slowly should help. If you begin to feel dizzy, sit or lie down for a few moments before standing. If this continues beyond the first few days, speak with your doctor. Do not drive and do not use tools or machines while you feel dizzy

Dolor de cabeza

Bebe mucha agua y pide a tu farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza persisten, informe a su médico.

Cansancio

Si esto ocurre, no conduzca ni utilice herramientas o máquinas hasta que se sienta más despierto.

Flushing, rash

Speak with your doctor if either of these become troublesome

Important: if you experience any of the following rare but serious symptoms, stop taking moexipril and contact your doctor for advice straightaway:

  • Dificultad para respirar o hinchazón de la cara, la boca, la lengua o la garganta. Son signos de una reacción alérgica.

  • Any yellowing of your skin or of the whites of your eyes. These may be signs of jaundice, which is a rare side-effect.

  • Una erupción cutánea grave.

Si experimenta cualquier otro síntoma que crea que puede deberse a los comprimidos, hable con su médico o farmacéutico para que le aconsejen.

How to store moexipril

  • Mantenga todos los medicamentos fuera de la vista y del alcance de los niños.

  • Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.

Información importante sobre todos los medicamentos

Información importante sobre todos los medicamentos

No tome nunca más de la dosis prescrita. Si sospecha que usted u otra persona ha tomado una sobredosis de este medicamento, acuda al servicio de urgencias de su hospital. Llévese el envase, aunque esté vacío.

Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.

No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.

Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.

MHRA - Notificación de reacciones adversas

Notifique a la Agencia Reguladora de Medicamentos y Productos Sanitarios las sospechas de efectos secundarios de medicamentos, vacunas, cigarrillos electrónicos, incidentes con productos sanitarios o productos defectuosos o falsificados para garantizar un uso seguro y eficaz.

Lecturas complementarias y referencias

Historia del artículo

La información de esta página ha sido redactada y revisada por médicos cualificados.

  • Fecha de la próxima revisión: 10 de diciembre de 2026
  • 11 dic 2023 | Última versión

    Última actualización

    Michael Stewart, MRPharmS

    Revisado por expertos

    Sid Dajani
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