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Nicardipine capsules

Cardene

Nicardipine is prescribed for high blood pressure, and to prevent angina.

When you first start taking the capsules you may get a headache or feel flushed. These symptoms usually go after a few days.

You can take nicardipine capsules before or after meals.

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About nicardipine

Tipo de medicamento

Un bloqueador de los canales de calcio

Usado para

High blood pressure; to prevent angina

También llamado

Cardene®

Disponible como

Cápsulas e inyección

Nicardipine belongs to a group of medicines called bloqueadores de los canales de calcio. It is prescribed to treat presión arterial alta (hipertensión), or to prevent dolor de pecho por angina. You will have been prescribed it for one of these reasons.

It works by causing some of your blood vessels to relax and widen. This lowers your blood pressure. It also reduces the force and the rate of your heartbeat, and this helps to prevent angina chest pain. It does these things by blocking the amount of calcium that goes into the 'smooth' muscle cells in the walls of your arteries and in your heart. Calcium is needed for muscles to contract, so reducing the amount of calcium causes the muscle cells to relax.

In some countries nicardipine is available as a modified-release capsule. This means that the capsules release nicardipine more slowly than the standard capsules. They can be prescribed for people with high blood pressure.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking nicardipine it is important that your doctor knows:

  • If you have any heart problems (other than angina or high blood pressure), or if you have recently had a heart attack.

  • If you have angina pain when you are resting as well as when you are active.

  • If you have been told you have narrowing of the main blood vessel from your heart (aortic stenosis).

  • Si estás embarazada o amamantando.

  • If you have problems with the way your liver works, or problems with the way your kidneys work.

  • Si está tomando o usando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.

  • Si alguna vez has tenido una reacción alérgica a un medicamento.

  • Si tienes un trastorno sanguíneo hereditario raro llamado porfiria.

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  • Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. It will give you more information about nicardipine and will provide you with a full list of the side-effects which you may experience from taking the capsules.

  • Standard nicardipine capsules (Cardene®) are taken three times a day. There are two strengths available - 20 mg and 30 mg. You will be prescribed the lower-strength capsule first, and then the higher-strength capsule after a few days if your doctor feels it is necessary.

  • Modified-release capsules are taken twice daily - morning and evening. There are three strengths available - 30 mg, 45 mg and 60 mg. You will be prescribed the lower-strength capsule to begin with and your dose adjusted later if needed.

  • Space out your doses during the day, and try to take them at the same times each day as this will help you to remember to take your doses regularly. Swallow the capsules whole with a drink of water. You can take nicardipine before or after meals.

  • Si olvida tomar una dosis, tómela tan pronto como lo recuerde. Si cuando lo recuerda, ya es casi la hora de su próxima dosis, entonces tome su próxima dosis cuando corresponda, pero omita la dosis olvidada. No tome dos dosis juntas para compensar una dosis olvidada.

  • Intenta mantener tus citas regulares con tu médico. Esto es para que tu médico pueda verificar tu progreso.

  • Your doctor will discuss with you the possibility of unwanted side-effects. When you first start taking nicardipine you may experience headaches, feeling flushed, and some dizziness. These effects usually only last for a few days, but if they continue or become troublesome, you should let your doctor know.

  • If you drink alcohol, ask your doctor for advice. Your doctor may recommend that you do not drink alcohol while you are on nicardipine as it can increase the chance that you experience side-effects, such as feeling dizzy or light-headed.

  • You should not drink grapefruit juice while you are on nicardipine. This is because a chemical in grapefruit juice increases the amount of nicardipine in your blood and this makes side-effects more likely.

  • Nicardipine is a medicine which helps to prevenir angina pain from developing, it will not provide you with immediate pain relief if you have an angina attack. Your doctor will give you a different medicine to take for this.

  • If you buy any medicines, always check with a pharmacist that they are suitable to take with your other medicines. Some anti-inflammatory painkillers can reduce the effectiveness of nicardipine.

  • If you need to have an operation or any medical treatment, tell the person carrying out the treatment which medicines you are taking. Nicardipine and some anaesthetics can interact and may cause your blood pressure to drop too low.

  • Treatment with nicardipine is usually long-term unless you experience an adverse effect. Continue to take the capsules unless you are told otherwise by your doctor. If it is necessary for you to stop, your doctor may want you to reduce your dose over a few days, as there is some evidence to suggest that stopping taking nicardipine suddenly can cause some symptoms to return.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with nicardipine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common nicardipine side-effects

¿Qué puedo hacer si experimento esto?

Headache, feeling hot or flushed

These may occur when you first start treatment, but usually go away after a few days. If the headache continues discuss the problem with your doctor

Sentirse mal (náuseas) o estar enfermo (vómitos)

Mantente en alimentos simples - evita comidas ricas o picantes

Sensación de mareo

No conduzca ni utilice herramientas o máquinas mientras esté afectado

Swollen ankles, being aware of fast heartbeats (palpitations)

Speak with your doctor about these if troublesome

Importante: a few people taking nicardipine have experienced worsening of chest pain at the start of treatment or after a dose increase - if this happens to you, you must let your doctor know straightaway.

If you experience any other symptoms which you think may be due to the capsules, you should speak with your doctor or pharmacist for further advice.

  • Mantenga todos los medicamentos fuera del alcance y la vista de los niños.

  • Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.

Información importante sobre todos los medicamentos

Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.

Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.

No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.

Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.

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Lecturas adicionales y referencias

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Historial del artículo

La información en esta página está escrita y revisada por pares por clínicos calificados.

  • Próxima revisión: 30 de noviembre de 2026
  • 1 Dic 2023 | Última versión

    Última actualización por

    Michael Stewart, MRPharmS

    Revisado por pares por

    Sid Dajani
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