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Lamivudine for hepatitis B infection

Zeffix

Lamivudine is an antiretroviral medicine. You have been prescribed it for chronic hepatitis B infection.

Take one (100 mg) tablet daily. You can take your doses either before or after meals.

Each time you collect a new supply of tablets from your pharmacy, make sure they look to be the same as you have had before. If you are unsure, ask your pharmacist to check it out for you.

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About lamivudine for hepatitis B infection

Tipo de medicamento

Un medicamento antirretroviral inhibidor nucleósido de la transcriptasa inversa

Utilizado para

Hepatitis B in adults

También llamado

Zeffix®

Disponible como

Tabletas

Hepatitis means inflammation of the liver. Some viruses can cause hepatitis (although there are several other causes too). Hepatitis B is a virus which is carried in your bloodstream to your liver. It can affect and damage your liver. Following an infection with hepatitis B, a few people develop a persistent infection called chronic hepatitis B.

People with chronic hepatitis B usually need treatment to stop or to reduce the activity of the virus. This limits damage to the liver, which is a complication of the infection. One of the types of treatment currently given is an antiviral medicine. Antiviral medicines like lamivudine work by stopping the hepatitis B virus from multiplying (replicating); this reduces the amount of the virus in your body. A doctor who is a liver specialist will usually start the treatment for you. Treatment for chronic hepatitis B usually continues for several years and can include more than one antiviral medicine.

Lamivudine is also prescribed for another viral infection - there is more information about this in a separate medicine leaflet called Lamivudine for HIV.

Before taking lamivudine

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking lamivudine it is important that your doctor knows:

  • Si está embarazada o en periodo de lactancia.

  • Si tiene problemas con el funcionamiento de los riñones.

  • Si está tomando otros medicamentos. Esto incluye todos los medicamentos que se pueden comprar sin receta, así como las hierbas medicinales y los medicamentos complementarios.

  • Si alguna vez ha tenido una reacción alérgica a un medicamento.

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How to take lamivudine

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside your pack. It will give you more information about lamivudine, and it will also provide you with a full list of the side-effects which you could experience from taking it.

  • The usual dose is one 100 mg tablet daily. Take lamivudine exactly as your doctor tells you to - your dose will be printed on the label of the pack to remind you about what the doctor said to you.

  • It is recommended that you swallow the tablet whole (not chewed or crushed). Take it with a drink of water.

  • Try to take lamivudine at the same time each day, as this will help you to remember to take it regularly. You can take the tablet either with or without food.

  • If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, leave out the missed dose. Do not take two doses together to make up for a forgotten dose.

Aproveche al máximo su tratamiento

  • Keep your regular appointments with your doctor. This is so that your progress can be monitored. You will need to have some blood tests from time to time.

  • It is important that you continue to take lamivudine regularly. Treatment for hepatitis B can be long-term. Continue to take the tablets, even if you feel well. This is to keep your liver healthy.

  • Treatment with lamivudine does not stop you from passing the infection on to others through sexual contact, sharing needles to inject drugs, or from mother to baby. A vaccine is available which protects against hepatitis B and can be offered to your sexual and household contacts who are at risk of being infected. Do not have sex with anyone (especially any sex without using a condom) until they have been fully immunised and have had their blood checked to see that the immunisation has worked.

  • A la mayoría de las personas con hepatitis B crónica se les recomienda seguir una dieta sana y equilibrada. Sin embargo, es probable que se le recomiende no beber alcohol. El alcohol aumenta el riesgo y la rapidez con que se producen lesiones hepáticas.

  • Each time you collect a new supply of these tablets from your pharmacy, make sure they look to be the same as you have had before. This is because there is another brand of lamivudine available which is used to treat a different type of infection. If you are unsure about your prescription in any way, ask your pharmacist to check it out for you.

  • Lamivudine has been associated with a serious side-effect in some people who have taken it for another type of infection. This is known as lactic acidosis. It is a problem where there is too much lactic acid in the blood. The symptoms associated with it are listed in the next section 'Can lamivudine cause problems?'. Although this has occurred in only a very few people who have taken it for hepatitis B, you must let your doctor know straightaway if you develop any of the symptoms listed below.

  • If you buy any medicines, supplements or herbal remedies 'over the counter', check with a pharmacist that they are suitable to take with lamivudine and your other medicines.

  • Si va a someterse a una operación o a un tratamiento dental, comunique a la persona que lleve a cabo el tratamiento qué medicamentos está tomando.

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Can lamivudine cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with lamivudine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common lamivudine side-effects


¿Qué puedo hacer si me ocurre esto?

Dolor de cabeza

Bebe mucha agua y pide a un farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza persisten, informe a su médico.

Cansancio

No conduzca ni utilice herramientas o máquinas mientras esté afectado. Si esto continúa, hable con su médico

Tummy (abdominal) discomfort, feeling sick (nausea) or being sick (vomiting)

Limítate a comidas sencillas: evita los alimentos ricos o picantes. Si continúa, hable con su médico

Diarrea

Beber mucha agua

Itchy rash, muscle cramps and pains, respiratory tract infections, sore throat

Si alguno se vuelve molesto, hable con su médico

Cambios en algunos análisis de sangre

Su médico comprobará

  • Sentirse mal (náuseas) o estar enfermo (vómitos), dolor de barriga, pérdida de apetito, pérdida de peso, sensación de debilidad o mareo y respiración rápida o jadeante.

Si experimenta cualquier otro síntoma que crea que puede deberse a los comprimidos, hable con su médico o farmacéutico para que le aconsejen.

How to store lamivudine

  • Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.

  • Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.

Información importante sobre todos los medicamentos

Información importante sobre todos los medicamentos

No tome nunca más de la dosis prescrita. Si sospecha que usted u otra persona ha tomado una sobredosis de este medicamento, acuda inmediatamente al servicio de urgencias de su hospital. Llévese el envase, aunque esté vacío.

Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.

No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.

Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.

Informar de los efectos secundarios de un medicamento o vacuna

Si experimenta efectos secundarios, puede notificarlos en línea a través del sitio web de la Tarjeta Amarilla.

Lecturas complementarias y referencias

Historia del artículo

La información de esta página ha sido redactada y revisada por médicos cualificados.

  • Fecha límite de la próxima revisión: 27 feb 2027
  • 30 ago 2022 | Última versión

    Última actualización

    Michael Stewart, MRPharmS

    Revisado por expertos

    Sid Dajani
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