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Lamivudina para la infección por hepatitis B

Zeffix

Lamivudine is an antiretroviral medicine. You have been prescribed it for chronic hepatitis B infection.

Take one (100 mg) tablet daily. You can take your doses either before or after meals.

Each time you collect a new supply of tablets from your pharmacy, make sure they look to be the same as you have had before. If you are unsure, ask your pharmacist to check it out for you.

De un vistazo

  • Lamivudine is an antiviral medicine for adults with chronic hepatitis B infection.

  • It works by stopping the hepatitis B virus from multiplying.

  • Take one tablet daily, swallowed whole with water, at the same time each day.

  • Continue taking lamivudine regularly, even if you feel well.

  • This medicine does not stop you from passing the infection to others.

  • Let your doctor know if you develop symptoms of lactic acidosis, such as feeling sick or stomach pain.

  • Common side-effects include headache, tiredness, tummy discomfort, and diarrhoea.

About lamivudine for hepatitis B infection

Tipo de medicamento

Un medicamento antirretroviral inhibidor de la transcriptasa inversa nucleósido

Usado para

Hepatitis B in adults

También llamado

Zeffix®

Disponible como

Comprimidos

Hepatitis means inflammation of the liver. Some viruses can cause hepatitis (although there are several other causes too). Hepatitis B is a virus which is carried in your bloodstream to your liver. It can affect and damage your liver. Following an infection with hepatitis B, a few people develop a persistent infection called chronic hepatitis B.

People with chronic hepatitis B usually need treatment to stop or to reduce the activity of the virus. This limits damage to the liver, which is a complication of the infection. One of the types of treatment currently given is an antiviral medicine. Antiviral medicines like lamivudine work by stopping the hepatitis B virus from multiplying (replicating); this reduces the amount of the virus in your body. A doctor who is a liver specialist will usually start the treatment for you. Treatment for chronic hepatitis B usually continues for several years and can include more than one antiviral medicine.

Lamivudine is also prescribed for another viral infection - there is more information about this in a separate medicine leaflet called Lamivudina para el VIH.

Before taking lamivudine

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking lamivudine it is important that your doctor knows:

  • Si estás embarazada o amamantando.

  • Si tienes problemas con el funcionamiento de tus riñones.

  • Si está tomando otros medicamentos. Esto incluye cualquier medicamento que se pueda comprar sin receta, así como medicamentos herbales y complementarios.

  • Si alguna vez has tenido una reacción alérgica a un medicamento.

How to take lamivudine

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside your pack. It will give you more information about lamivudine, and it will also provide you with a full list of the side-effects which you could experience from taking it.

  • The usual dose is one 100 mg tablet daily. Take lamivudine exactly as your doctor tells you to - your dose will be printed on the label of the pack to remind you about what the doctor said to you.

  • It is recommended that you swallow the tablet whole (not chewed or crushed). Take it with a drink of water.

  • Try to take lamivudine at the same time each day, as this will help you to remember to take it regularly. You can take the tablet either with or without food.

  • Si olvida tomar una dosis, tómela tan pronto como lo recuerde. Si no lo recuerda hasta el día siguiente, omita la dosis olvidada. No tome dos dosis juntas para compensar una dosis olvidada.

Obteniendo el máximo de tu tratamiento

  • Keep your regular appointments with your doctor. This is so that your progress can be monitored. You will need to have some blood tests from time to time.

  • It is important that you continue to take lamivudine regularly. Treatment for hepatitis B can be long-term. Continue to take the tablets, even if you feel well. This is to keep your liver healthy.

  • Treatment with lamivudine does not stop you from passing the infection on to others through sexual contact, sharing needles to inject drugs, or from mother to baby. A vaccine is available which protects against hepatitis B and can be offered to your sexual and household contacts who are at risk of being infected. Do not have sex with anyone (especially any sex without using a condom) until they have been fully immunised and have had their blood checked to see that the immunisation has worked.

  • Most people with chronic hepatitis B will be advised to eat a normal healthy balanced diet. However, it is likely you will be advised not to drink alcohol. Alcohol will increase the risk and speed of you developing liver damage.

  • Each time you collect a new supply of these tablets from your pharmacy, make sure they look to be the same as you have had before. This is because there is another brand of lamivudine available which is used to treat a different type of infection. If you are unsure about your prescription in any way, ask your pharmacist to check it out for you.

  • Lamivudine has been associated with a serious side-effect in some people who have taken it for another type of infection. This is known as lactic acidosis. It is a problem where there is too much lactic acid in the blood. The symptoms associated with it are listed in the next section 'Can lamivudine cause problems?'. Although this has occurred in only a very few people who have taken it for hepatitis B, you must let your doctor know de inmediato if you develop any of the symptoms listed below.

  • If you buy any medicines, supplements or herbal remedies 'over the counter', check with a pharmacist that they are suitable to take with lamivudine and your other medicines.

  • Si vas a someterte a una operación o tratamiento dental, informa a la persona que realiza el tratamiento sobre los medicamentos que estás tomando.

Can lamivudine cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with lamivudine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common lamivudine side-effects


¿Qué puedo hacer si experimento esto?

Dolor de cabeza

Bebe mucha agua y pide a un farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza continúan, informa a tu médico

Sensación de cansancio

Do not drive and do not use tools or machines while affected. If this continues, speak with your doctor

Tummy (abdominal) discomfort, feeling sick (nausea) or being sick (vomiting)

Stick to simple meals - avoid rich or spicy food. If it continues, speak with your doctor

Diarrea

Bebe mucha agua

Itchy rash, muscle cramps and pains, respiratory tract infections, sore throat

If any becomes troublesome, speak with your doctor

Cambios en algunos análisis de sangre

Su médico verificará estos

  • Feeling sick (nausea) or being sick (vomiting), tummy pain, loss of appetite, loss of weight, feeling weak or dizzy, and fast or gasping breathing.

Si experimenta cualquier otro síntoma que crea que puede deberse a las tabletas, hable con su médico o farmacéutico para obtener más consejos.

How to store lamivudine

  • Mantenga todos los medicamentos fuera del alcance y la vista de los niños.

  • Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.

Información importante sobre todos los medicamentos

Información importante sobre todos los medicamentos

Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda de inmediato al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.

Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.

No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.

Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.

Informar efectos secundarios de un medicamento o vacuna

Si experimenta efectos secundarios, puede reportarlos en línea a través de Sitio web de Yellow Card.

verificador de síntomas

¿Inseguro sobre mezclar medicamentos?

Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.

Preguntas frecuentes

What is chronic hepatitis B, and why is it treated?

Chronic hepatitis B is a persistent infection of the liver by the hepatitis B virus. It requires treatment to reduce the virus's activity and prevent damage to the liver, which can lead to serious complications.

What is the role of a liver specialist in my treatment with lamivudine?

A doctor who specialises in liver conditions will typically initiate your treatment with lamivudine. This ensures you receive expert care and monitoring for your chronic hepatitis B.

How long will I need to take lamivudine?

Treatment for chronic hepatitis B, including lamivudine, usually continues for several years. It is a long-term commitment to keep your liver healthy and manage the infection.

Is it safe to drink alcohol while taking lamivudine for hepatitis B?

It is highly likely that you will be advised against drinking alcohol. Alcohol can significantly increase the risk and speed of liver damage, which you are already at risk of due to hepatitis B.

Why is it important for me to continue taking lamivudine even if I feel well?

It is crucial to continue taking lamivudine regularly, even if you feel well, because it helps to keep your liver healthy by stopping the hepatitis B virus from multiplying. Stopping treatment prematurely could lead to the virus becoming more active and causing further liver damage.

What should I do if I notice a change in the appearance of my lamivudine tablets when I collect a new prescription?

If your new supply of lamivudine tablets looks different from what you've had before, you should ask your pharmacist to verify it. There's another brand of lamivudine available for a different type of infection, so it's important to ensure you have the correct medication for hepatitis B.

What are the symptoms of lactic acidosis, and why should I be aware of them?

Lactic acidosis is a serious condition where there's too much lactic acid in the blood, and while rare, it has been associated with lamivudine. Symptoms include feeling sick or being sick, stomach pain, loss of appetite, weight loss, feeling weak or dizzy, and fast or gasping breathing. You must inform your doctor immediately if you experience any of these symptoms.

Lecturas adicionales y referencias

Sobre el autorVer biografía completa

Imagen del autor

Michael Stewart, MRPharmS

Gerente de Revisión de Folletos de Medicamentos – Contratista, Farmacéutico

BPharm (Hons), MRPharmS

Michael es un farmacéutico comunitario que ejerce en Midlands y South Yorkshire con más de 20 años de experiencia asesorando sobre medicamentos y condiciones médicas. Tiene una sólida formación en capacitación en atención médica, habiendo producido e impartido cursos de formación para equipos de farmacia y personal de entornos de atención residencial, incluidas enfermeras. También ha contribuido a juntas asesoras de farmacia para la gestión de condiciones de baja gravedad en la comunidad.

Acerca del revisor

Imagen del autor

Sid Dajani

Sultan Dajani se graduó en la Escuela de Farmacia de Londres en 1994 y se convirtió en el miembro más joven elegido para el consejo de la Sociedad Real de Farmacia desde su fundación en 1842.

Historial del artículo

La información en esta página está escrita y revisada por pares por clínicos calificados.

  • Próxima revisión: 27 feb 2027
  • 30 Ago 2022 | Última versión

    Última actualización por

    Michael Stewart, MRPharmS

    Revisado por pares por

    Sid Dajani
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