Adefovir para la hepatitis B
Hepsera
Revisado por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 27 oct 2022
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Adefovir is an antiviral medicine. You have been prescribed it for chronic hepatitis B infection.
The usual dose is one 10 mg tablet daily. You can take your doses either with or without food.
It is important to take adefovir regularly every day, preferably at the same time each day.
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About adefovir
Tipo de medicamento | Un medicamento antivírico |
Utilizado para | Chronic hepatitis B infection in adults |
También llamado | Adefovir dipivoxil; Hepsera® |
Disponible como | Tabletas |
Hepatitis means inflammation of the liver. Some viruses can cause hepatitis. Hepatitis B is a virus which is carried in your bloodstream to your liver, where it can affect and damage your liver. Following infection with hepatitis B, a few people develop a persistent infection called chronic hepatitis B.
People with chronic hepatitis B usually need treatment to stop or to reduce the activity of the virus. This limits damage to the liver, which is a complication of the infection. One of the types of treatment currently given is an antiviral medicine. Antiviral medicines like adefovir work by stopping the hepatitis B virus from multiplying (replicating); this reduces the amount of the virus in your body.
A doctor who is a liver specialist will usually start the treatment for you. Treatment for chronic hepatitis B usually continues for several years, but can be lifelong. It can include more than one antiviral medicine.
Before taking adefovir
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking adefovir it is important that your doctor knows:
Si está embarazada, esperando un bebé o en período de lactancia.
Si tiene algún problema con el funcionamiento de sus riñones.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que pueda adquirirse sin receta, así como medicamentos a base de plantas y complementarios.
Si alguna vez ha tenido una reacción alérgica a un medicamento.
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How to take adefovir
Before you start the treatment, read the manufacturer's printed information leaflet from inside your pack. It will give you more information about adefovir, and it will also provide you with a full list of the side-effects which you could experience from taking it.
Take adefovir exactly as your doctor tells you to. The usual dose is one 10 mg tablet daily. You can take the tablet either with or without food.
Try to take your doses at the same time of day each day, as this will help you to remember to take adefovir regularly.
If you are ever sick within one hour of taking a tablet, you should take a second tablet. This is because your body will not have absorbed a sufficient amount of the medicine. If, however, you are sick and it is more than one hour after taking a tablet, you do not need to take a second dose, as your body will have already absorbed the full dose.
If you forget to take a dose at your usual time, take it as soon as you remember. However, if you do not remember until the following day, leave out the missed dose. Do not take two doses together to make up for a forgotten dose.
Aproveche al máximo su tratamiento
Keep your regular appointments with your doctor. This is so that your progress can be monitored. You will need to have some blood tests from time to time.
It is important that you continue to take adefovir regularly. Treatment for hepatitis B can be long-term. Continue to take the tablets, even if you feel well. This is to keep your liver healthy.
Treatment with adefovir does not stop you from passing the infection on to others through sexual contact, sharing needles to inject drugs, or from mother to baby. A vaccine is available which protects against hepatitis B and can be offered to your sexual and household contacts who are at risk of being infected. Do not have sex with anyone (especially any sex without using a condom) until they have been fully immunised and have had their blood checked to see that the immunisation has worked.
A la mayoría de las personas con hepatitis B crónica se les recomienda seguir una dieta sana y equilibrada. Sin embargo, es probable que se le recomiende no beber alcohol. El alcohol aumenta el riesgo y la rapidez con que se producen lesiones hepáticas.
Medicines similar to adefovir have been associated with a serious side-effect in a few people. This is known as lactic acidosis. It is a problem where there is too much lactic acid in the blood. The symptoms associated with it are listed in the next section 'Can adefovir cause problems?'. Although this has occurred in only a very few people, you must let your doctor know straightaway if you develop the symptoms listed below.
You must avoid getting pregnant while you are taking adefovir. Make sure you have discussed with your doctor which types of contraception are suitable for you.
If you buy any medicines, supplements or herbal remedies 'over the counter', check with a pharmacist that they are suitable to take with adefovir and your other medicines.
Si va a someterse a una operación o a un tratamiento dental, comunique a la persona que lleve a cabo el tratamiento qué medicamentos está tomando.
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Can adefovir cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with adefovir. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common adefovir side-effects (these affect more than 1 in 10 people) | ¿Qué puedo hacer si me ocurre esto? |
Sensación de cansancio o debilidad | No conduzca ni utilice herramientas o máquinas mientras esté afectado. Si esto continúa, hable con su médico |
Cambios en algunos análisis de sangre | Su médico comprobará |
Common adefovir side-effects (afectan a menos de 1 de cada 10 personas) | ¿Qué puedo hacer si me ocurre esto? |
Feeling sick (nausea) or being sick (vomiting), indigestion, wind, tummy (abdominal) pain | Limítate a comidas sencillas: evita los alimentos grasos o picantes. Si continúa, hable con su médico |
Diarrea | Beber mucha agua para reponer los líquidos perdidos |
Dolor de cabeza | Bebe mucha agua y pide a un farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza persisten, informe a su médico. |
Erupción pruriginosa | En caso de molestias, hable con su médico |
Your doctor will discuss with you the possibility of this medicine causing a problem called lactic acidosis. Let your doctor know straightaway if you develop the following symptoms:
Sentirse mal (náuseas) o estar enfermo (vómitos), dolor de barriga, pérdida de apetito, pérdida de peso, sensación de debilidad o mareo y respiración rápida o jadeante.
Si experimenta cualquier otro síntoma que crea que puede deberse a los comprimidos, hable con su médico o farmacéutico para que le aconsejen.
How to store adefovir
Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
No tome nunca más de la dosis prescrita. Si sospecha que usted u otra persona ha tomado una sobredosis de este medicamento, acuda al servicio de urgencias de su hospital. Llévese el envase, aunque esté vacío.
Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.
No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.
Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.
Informar de los efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede notificarlos en línea a través del sitio web de la Tarjeta Amarilla.
Lecturas complementarias y referencias
- Manufacturer's PIL, Hepsera® 10 mg tablets; Gilead Sciences Ltd, Medicines.ie. Irish Pharmaceutical Healthcare Association. Dated April 2021.
- Medicamentos BNF completa 89ª edición; Asociación Médica Británica y Real Sociedad Farmacéutica de Gran Bretaña, Londres.
Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
Fecha límite de la próxima revisión: 26 Oct 2025
27 Oct 2022 | Última versión
29 de mayo de 2013 | Publicado originalmente
Autores:
Helen Allen, Farmacéutica

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