Tabletas de Maraviroc para el VIH
Celsentri
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 20 Jul 2022
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Maraviroc slows the progress of HIV infection. It is one of a number of medicines that you will need to take regularly.
Take the tablets exactly as your doctor tells you to.
Maraviroc has been associated with some side-effects. Your doctor will discuss these with you before you start treatment.
De un vistazo
Maraviroc is an antiretroviral medicine used to treat human immunodeficiency virus (HIV) infection.
It slows the progress of HIV but is not a cure.
It works by blocking HIV from entering your cells, helping to maintain your immune system.
Maraviroc is taken with other medicines, usually twice daily, and often for life.
You must take it exactly as prescribed to prevent drug resistance.
Tell your doctor if you have liver or kidney problems, heart issues, or take other medicines.
Serious side-effects needing urgent medical attention include yellowing skin or eyes, dark urine, or severe rash.
About maraviroc
Tipo de medicamento | A CCR5 antagonist antiretroviral medicine |
Usado para | Human immunodeficiency virus (HIV) infection in adults |
También llamado | Celsentri® |
Disponible como | Tabletas y medicina líquida oral |
Maraviroc is an antiretroviral medicine. It is used for infección por el virus de la inmunodeficiencia humana (VIH). It slows the progress of HIV infection but it is not a cure. HIV destroys cells in the body, called CD4 T cells. These cells are a type of white blood cell and are important because they are involved in protecting your body from infection. If left untreated, the HIV infection weakens your immune system so that your body cannot defend itself against bacteria, viruses and other germs. Maraviroc is known as a CCR5 antagonist antiretroviral medicine. It works by blocking a receptor, called CCR5, which HIV uses to enter your CD4 T cells. By reducing the amount of virus getting into your cells, it helps to maintain the health of your immune system.
Maraviroc will be prescribed for you by a doctor who is a specialist. it is given alongside a number of other antiretroviral medicines, as part of a combination therapy. Taking three or more antiretroviral medicines at the same time is more effective than taking one alone. Taking a combination of different medicines also reduces the risk that the virus will become resistant to any individual medicine. It is vital to take them exactly as prescribed to maintain success and to help to prevent the virus from becoming resistant to the medicines. These medicines are usually taken for life.
Before taking maraviroc
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking maraviroc it is important that your doctor knows:
Si estás embarazada o amamantando.
Si tienes algún problema con el funcionamiento de tu hígado, o si tienes algún problema con el funcionamiento de tus riñones.
If you have any problems with your heart or blood vessels.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que se pueda comprar sin receta, así como medicamentos herbales y complementarios.
If you have ever had an allergic reaction to a medicine, or if you are allergic to peanuts or soya.
How to take maraviroc
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about maraviroc, and it will also provide you with a full list of the side-effects which you could experience from taking it.
Take maraviroc exactly as your doctor tells you to. It is usual to take one 300 mg tablet twice daily, although your dose may be more or less than this depending upon which other medicines you are also taking.
If you (or your child) have been supplied with oral liquid medicine, follow the instructions in the pack for measuring out the correct dose using the syringe and adapter provided.
Your dose of maraviroc can be taken with or without food.
Try to take your doses at the same times of day each day, as this will help you to remember to take maraviroc regularly.
If you do forget to take a dose, take it as soon as you remember (unless it is nearly time for your next dose, in which case leave out the missed dose). Do not take two doses together to make up for a forgotten dose.
Obteniendo el máximo de tu tratamiento
Mantén tus citas regulares con tu médico para que se pueda monitorear tu progreso. Necesitarás hacerte análisis de sangre regularmente.
It is important that you continue to take maraviroc and your other antiretroviral treatment regularly. This will help to prevent the HIV from becoming resistant to the medicines you are taking. Even if you miss only a small number of doses, the virus can become resistant to treatment.
If you develop any infection soon after you start the treatment, let your doctor know. As a result of taking maraviroc, your immune system may start fighting an infection which was present before you started the treatment, but which you may not have been aware of.
Follow carefully any advice your doctor gives to you about making some lifestyle changes to reduce any risk of damage to your heart and blood vessels. These can include stopping smoking, eating healthily and taking regular exercise.
Although treatment with antiretroviral medicines can reduce the risk of you passing HIV to others through sexual contact, it does not stop it. It is important that you use condoms.
It is not uncommon for people with HIV to feel low or even depressed, especially soon after the diagnosis has been made and treatment has been started. If you have any feelings of depression you should speak with your doctor straightaway.
Algunas personas que han tomado medicamentos antirretrovirales (particularmente durante un largo período) han desarrollado una condición llamada osteonecrosis. Esta es una enfermedad ósea donde el tejido óseo muere debido a una reducción en el suministro de sangre. Esto lleva a dolores articulares y rigidez, y puede causar dificultades en el movimiento. Si nota alguno de estos síntomas, hable con su médico.
If you buy any medicines or herbal remedies 'over the counter', check with a pharmacist that they are suitable to take alongside maraviroc and your other medicines. This is because some medicines interfere with antiretrovirals and can stop them from working properly.
If you are having an operation or dental treatment, always tell the person carrying out the treatment which medicines you are taking.
Treatment for HIV is usually lifelong. Continue to take maraviroc regularly, even if you feel well. This is to keep your immune system healthy.
Can maraviroc cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with maraviroc. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Común maraviroc side-effects (these affect fewer than 1 in 10 people) | ¿Qué puedo hacer si experimento esto? |
Feeling sick (nausea), wind, tummy (abdominal) pain | Stick to simple meals - avoid fatty or spicy food |
Feeling tired, weak, or dizzy | No conduzca ni utilice herramientas o máquinas mientras esté afectado |
Diarrea | Bebe mucha agua para reponer los líquidos perdidos |
Dolor de cabeza | Bebe mucha agua y pide a un farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza continúan, informa a tu médico |
Loss of weight, feeling low or depressed, problems sleeping, skin rash | Si alguno de estos se vuelve problemático, informe a su médico |
Cambios en algunos análisis de sangre | Su médico verificará esto |
Importante: occasionally, some people taking maraviroc have developed more serious side-effects. If you experience any of the following, let your doctor know straightaway. These can be signs of a problem with your liver and/or an allergic reaction:
Loss of appetite, sickness, high temperature (fever), dark urine, stomach pain, extreme tiredness.
Yellowing of your skin or the whites of the eyes (jaundice).
Severe itchy skin rash.
Si experimenta cualquier otro síntoma que crea que puede deberse a las tabletas, hable con su médico o farmacéutico para obtener más consejos.
How to store maraviroc
Mantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
The oral liquid medicine should not be used after 60 days since first opening. Write the date you opened the bottle on the label to remind you.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda de inmediato al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Sitio web de Yellow Card.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Preguntas frecuentes
What is the specific role of the CCR5 receptor that maraviroc targets?
The CCR5 receptor is a chemical channel that HIV uses as an entry point to get into the body's CD4 T cells. By blocking this receptor, maraviroc helps to prevent the virus from entering these cells, thereby reducing the viral load and preserving the health of the immune system.
What happens if I already have an infection when I start taking maraviroc?
If you develop an infection shortly after starting maraviroc, you should inform your doctor. It's possible that maraviroc may activate your immune system to begin fighting an infection that was already present in your body but you were not aware of before starting the treatment.
Can I stop using condoms if I am taking maraviroc and my other HIV medicines regularly?
No. While treatment with antiretroviral medicines like maraviroc can lower the risk of transmitting HIV to others through sexual contact, it does not completely eliminate this risk. It is still crucial to use condoms consistently to prevent transmission.
What should I do if I start feeling sad or depressed after starting maraviroc?
It is quite common for people with HIV to experience feelings of sadness or depression, especially after a diagnosis or when starting treatment. If you notice yourself feeling depressed, you should talk to your doctor immediately.
Does long-term use of maraviroc have any specific bone-related side effects?
Yes, some individuals who have taken antiretroviral medicines, particularly over an extended period, have developed a condition called osteonecrosis. This bone disease occurs when bone tissue dies due to insufficient blood supply, leading to joint pains, stiffness, and difficulty with movement. If you experience these symptoms, you should consult your doctor.
Lecturas adicionales y referencias
- Manufacturer's PIL, Celsentri® 25 mg, 75 mg, 150 mg and 300 mg film-coated tablets; ViiV Healthcare UK Ltd, The electronic Medicines Compendium. Dated March 2021.
- Manufacturer's PIL, Celsentri® 20 mg/ml oral solution; ViiV Healthcare UK Ltd, The electronic Medicines Compendium. Dated March 2021.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
Sobre el autorVer biografía completa

Michael Stewart, MRPharmS
Gerente de Revisión de Folletos de Medicamentos – Contratista, Farmacéutico
BPharm (Hons), MRPharmS
Michael es un farmacéutico comunitario que ejerce en Midlands y South Yorkshire con más de 20 años de experiencia asesorando sobre medicamentos y condiciones médicas. Tiene una sólida formación en capacitación en atención médica, habiendo producido e impartido cursos de formación para equipos de farmacia y personal de entornos de atención residencial, incluidas enfermeras. También ha contribuido a juntas asesoras de farmacia para la gestión de condiciones de baja gravedad en la comunidad.
Acerca del revisor

Sid Dajani
Sultan Dajani se graduó en la Escuela de Farmacia de Londres en 1994 y se convirtió en el miembro más joven elegido para el consejo de la Sociedad Real de Farmacia desde su fundación en 1842.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Artículo también disponible en Inglés, Alemán, Español, Francés, Italiano, Portugués, Hindi, Hebreo, Árabe, y Sueco.
Próxima revisión: 19 Ene 2027
20 Jul 2022 | Última versión

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