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Codeine for pain relief

Este medicamento es un analgésico opiáceo. Existe un grave riesgo de adicción al tomar este medicamento, especialmente si se utiliza a largo plazo. La Agencia Reguladora de Medicamentos y Productos Sanitarios (MHRA) ha publicado nuevas orientaciones para las personas a las que se prescriben analgésicos opioides. Si tiene alguna pregunta o duda sobre cómo tomar opiáceos de forma segura, hable con su médico o farmacéutico.

Codeine is used to treat mild-to-moderate types of pain.

The most common side-effects are feeling sick (nausea), constipation, feeling sleepy, and dry mouth.

Codeine may affect your reactions. When you first start treatment, do not drive until you know how you react.

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About codeine

Tipo de medicamento

An opioid painkiller (analgesic)

Utilizado para

Alivio del dolor

También llamado

Codeine phosphate

Disponible como

Comprimidos, medicamentos orales líquidos e inyectables

Codeine is an opioid medicine (sometimes called an opiate). It is used to treat mild-to-moderate types of pain. It can be particularly useful when painkillers such as paracetamol and ibuprofen have not been effective. It works by binding to certain tiny areas, called opioid receptors, in your central nervous system (brain and spinal cord). This leads to a decrease in the way you feel pain and your reaction to pain. Codeine is available on a prescription from a doctor.

Codeine is also contained in a number of combination medicines, some of which can be bought over-the-counter, without a prescription, in pharmacies. In particular, it is available in combination with the painkiller paracetamol in a medicine called co-codamol. There is a separate medicine leaflet called Co-codamol for pain relief which explains about this medicine. Codeine is also combined with the anti-inflammatory medicine ibuprofen in some over-the-counter products.

Before taking codeine

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking codeine, it is important that your doctor knows:

  • Si está embarazada o en periodo de lactancia.

  • Si tiene algún problema con el funcionamiento del hígado o de los riñones.

  • Si tiene problemas de próstata o dificultades para orinar.

  • Si tiene algún problema respiratorio, como asma o enfermedad pulmonar obstructiva crónica (EPOC).

  • If you have been told you have low blood pressure or an abnormal heart rhythm.

  • Si tiene problemas de tiroides o glándulas suprarrenales.

  • Si padece epilepsia.

  • If you have gallstones or a problem with your bile duct.

  • Si ha estado estreñido durante más de una semana o tiene un problema inflamatorio intestinal.

  • Si padece una enfermedad que causa debilidad muscular, llamada miastenia gravis.

  • Si ha sufrido recientemente un traumatismo craneoencefálico grave.

  • If you have ever been dependent on drugs or alcohol.

  • Si alguna vez ha tenido una reacción alérgica a un medicamento.

  • Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que pueda adquirirse sin receta, así como medicamentos a base de plantas y complementarios.

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How to take codeine

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about codeine and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take codeine exactly as your doctor tells you to. The usual dose for pain relief is 30-60 mg every four hours if needed. The dose should not be repeated more frequently than every four hours, and it is important that you do not take more than a maximum daily amount of 240 mg. As there are several different strengths of tablets available, your doctor or pharmacist will tell you how many tablets to take for each dose. This information will also be printed on the label of the pack to remind you.

  • Swallow the tablets with a drink of water. You can take codeine either before or after food, but taking the tablets after food can help prevent feelings of sickness which can occur with the first few doses.

  • If you forget to take a dose, take it as soon as you remember and then continue taking your doses every four hours if needed, as before. Do not take two doses together to make up for a forgotten dose.

Aproveche al máximo su tratamiento

  • You should not drink alcohol while you are taking codeine. This is because codeine will increase the risk that you experience side-effects from the alcohol, such as feeling dizzy and sleepy.

  • Codeine is likely to affect your reactions and ability to drive. It is an offence to drive while your reactions are impaired. Do not drive until you know how you react, especially when you first start treatment. Please also be aware that the effects of codeine can last into the following day. Even if your driving ability is not impaired, you are advised to carry with you some evidence that the medicine has been prescribed for you - a repeat prescription form or a patient information leaflet from the pack is generally considered suitable.

  • You will not be given codeine for longer than is necessary. This is because when you take codeine repeatedly over a period of time and then stop taking it, it can cause withdrawal symptoms such as making you feel restless or irritable. If you have been taking it for some time and want to stop it, your doctor will recommend that you reduce your dose slowly in order to avoid the risk of these effects.

  • Codeine is normally prescribed for short periods of pain. If you take it over a longer period of time, your body can become used to it and it will not work as well. This is called tolerance.

  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking codeine.

  • If you buy any medicines, check with a pharmacist that they are safe to take with codeine.

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Can codeine cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with codeine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common codeine side-effects

¿Qué puedo hacer si me ocurre esto?

Sentirse mal (náuseas) o estar enfermo (vómitos)

Stick to simple meals - avoid rich or spicy foods. Also, try taking your doses of codeine after food, as this may help protect your stomach

Estreñimiento

Eat a well-balanced diet and drink plenty of water each day. If this continues to be a problem, speak with your doctor

Sensación de mareo o sueño

Si esto ocurre, no conduzca ni utilice herramientas o máquinas. No bebas alcohol

Dry mouth, sweating, tummy pain (may be caused by spasm of the bile ducts)

Hable con su médico en caso de molestias

Important: people taking opioid medicines, and their family and friends, should be aware of the risk of accidental overdose and know when to seek medical help. The risk is higher if you also take other medicines that make you feel drowsy. Signs you have taken too much medicine include:

  • Sentirse muy somnoliento o mareado.

  • Sentirse enfermo (náuseas) o estar enfermo (vómitos).

  • Dificultades respiratorias.

  • Pérdida de conocimiento.

If you have taken more codeine than you should or someone else accidentally swallows your medication, call for an ambulance and tell them the name of your medicine.

If you experience other symptoms which you think may be due to codeine, speak with your doctor or pharmacist for further advice.

How to store codeine

  • Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.

  • Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.

Información importante sobre todos los medicamentos

Información importante sobre todos los medicamentos

No tome nunca más de la dosis prescrita. Si sospecha que usted u otra persona ha tomado una sobredosis de este medicamento, acuda al servicio de urgencias de su hospital. Llévese el envase, aunque esté vacío.

Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.

No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.

Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.

MHRA - Notificación de reacciones adversas

Notifique a la Agencia Reguladora de Medicamentos y Productos Sanitarios las sospechas de efectos secundarios de medicamentos, vacunas, cigarrillos electrónicos, incidentes con productos sanitarios o productos defectuosos o falsificados para garantizar un uso seguro y eficaz.

Lecturas complementarias y referencias

Historia del artículo

La información de esta página ha sido redactada y revisada por médicos cualificados.

  • Fecha de la próxima revisión: 17 de diciembre de 2026
  • 18 dic 2023 | Última versión

    Última actualización

    Michael Stewart, MRPharmS

    Revisado por expertos

    Sid Dajani
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