Pizotifeno comprimidos
Peer reviewed by Sid DajaniLast updated by Michael Stewart, MRPharmSLast updated 17 Apr 2025
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Pizotifen helps to stop migraine-type headaches from occurring.
Tome los comprimidos regularmente todos los días.
Having an increased appetite and feeling sleepy are the main side-effects.
En este artículo:
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About pizotifen
Tipo de medicamento | An antimigraine medicine |
Utilizado para | To prevent migraines and migraine-type headaches (in adults and older children) |
También llamado | Pizotyline (in US) |
Disponible como | Tabletas |
Pizotifen is taken to prevent troublesome headaches such as migraine and recurrent throbbing headaches. It is also used to treat cluster headaches. These are headaches which occur in close succession at certain times of the year, usually lasting 6-12 weeks.
Your body produces chemicals which, in some cases, may be involved in causing headaches. These chemicals are 'serotonin', 'tryptamine' and 'histamine'. Pizotifen helps to stop the effect of these chemicals.
Pizotifen must be taken every day to help stop migraine attacks from starting. It may not completely stop every migraine attack, but the number and severity of your attacks should reduce. Although it can help to reduce the number of attacks you have, it is not effective in relieving a migraine attack that has already started.
Before taking pizotifen
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking pizotifen it is important that your doctor knows:
Si está embarazada o en periodo de lactancia.
If you have increased pressure in your eye, a condition called glaucoma.
Si tiene dificultades para orinar.
If you have ever had fits or epilepsy.
Si tiene algún problema con el funcionamiento de su hígado, o si tiene algún problema con el funcionamiento de sus riñones.
Si está tomando otros medicamentos. Esto incluye todos los medicamentos que se pueden comprar sin receta, así como las hierbas medicinales y los medicamentos complementarios.
Si alguna vez ha tenido una reacción alérgica a un medicamento.
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How to take pizotifen
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about pizotifen, and will also provide you with a full list of the side-effects which you could experience from taking it.
Take the tablets exactly as your doctor tells you to. You will find the directions for taking the tablets on the label of the pack to remind you about what the doctor said to you. There are two strengths of tablet: 500 micrograms and 1.5 mg. It is usual to begin by taking one 500 microgram tablet a day at bedtime. Your dose may then be gradually increased to the usual maintenance dose of 1.5 mg daily (taken as one single daily dose at bedtime, or divided into three smaller doses).
Swallow the tablet with a drink of water. Try to take your doses at the same time(s) of day each day, as this will help you to remember to take pizotifen regularly. You can take the tablet either with or without food.
Si olvida tomar una dosis a la hora habitual, tómela en cuanto se acuerde (a menos que sea casi la hora de la siguiente dosis, en cuyo caso omita la dosis olvidada y tome la siguiente dosis normalmente). No tome dos dosis juntas para compensar la dosis olvidada.
Aproveche al máximo su tratamiento
Procure acudir a las citas periódicas con su médico. Así podrá comprobar su evolución.
For some people there may be things which trigger an attack. These can include some foods (for example, cheese, chocolate, and red wine), worry, bright sunlight, too much or too little sleep, and skipping meals. Try to avoid things that you suspect trigger your headaches.
Pizotifen can cause sleepiness. Your doctor may recommend that you do not drink alcohol while you are taking the tablets, as alcohol will increase the drowsiness.
It is unlikely that pizotifen will stop your headaches completely. You may find it useful to keep a migraine diary to monitor how well it is working. Note down when and where each attack started, what you were doing, and what you had eaten that day. A pattern may emerge and it may be possible for you to avoid some of the things that trigger your attacks.
If a migraine attack occurs despite taking pizotifen, you can still take painkillers or a triptan medicine to ease the pain and sickness.
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Can pizotifen cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with pizotifen. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common pizotifen side-effects (these affect more than 1 in 10 people) | ¿Qué puedo hacer si me ocurre esto? |
Aumento del apetito y del peso | Try to eat a well-balanced diet |
Common pizotifen side-effects (these affect fewer than 1 in 10 people) | ¿Qué puedo hacer si me ocurre esto? |
Feeling sleepy, or tired | No conduzca ni utilice herramientas o máquinas mientras esté afectado. No beba alcohol |
Boca seca | Prueba a mascar chicle sin azúcar o chupar caramelos sin azúcar |
Sensación de malestar (náuseas) | Coma alimentos sencillos: evite las comidas grasas o picantes. |
Si experimenta cualquier otro síntoma que crea que puede deberse a los comprimidos, hable con su médico o farmacéutico para que le aconsejen.
How to store pizotifen
Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
No tome nunca más de la dosis prescrita. Si sospecha que usted u otra persona ha tomado una sobredosis de este medicamento, acuda inmediatamente al servicio de urgencias de su hospital. Llévese el envase, aunque esté vacío.
Si va a someterse a una operación o a un tratamiento dental, comunique a la persona que lleve a cabo el tratamiento qué medicamentos está tomando.
Si compra algún medicamento, compruebe con un farmacéutico que es adecuado para tomarlo con sus otros medicamentos.
Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.
No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.
Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.
Informar de los efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede notificarlos en línea a través del sitio web de la Tarjeta Amarilla.
Lecturas complementarias y referencias
- Manufacturer's PIL, Pizotifen 500 mcg and 1.5 mg tablets; Sovereign Medical. The electronic Medicines Compendium. Dated July 2024.
- Medicamentos BNF completa 89ª edición; Asociación Médica Británica y Real Sociedad Farmacéutica de Gran Bretaña, Londres.
Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
Next review due: 17 Apr 2028
17 Apr 2025 | Latest version

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