Fenitoína para la epilepsia
Epanutin
Revisado por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 2 Ene 2024
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Try to keep your regular doctor's appointments. Your doctor may need to test your blood to decide the correct dose for you.
You need to take phenytoin regularly. Do not stop taking it unless your doctor tells you to.
Different formulations and brands of phenytoin can act in a slightly different way in your body. Each time you collect a prescription, check to make sure your supply looks the same as you have had before. If not, please ask your pharmacist to check your prescription for you.
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About phenytoin
Tipo de medicamento | Un medicamento antiepiléptico |
Utilizado para | Epilepsy in children and adults; trigeminal neuralgia |
También llamado | Phenytoin sodium, Epanutin® |
Disponible como | Tablets, capsules, chewable tablets and oral liquid medicine |
If you have epilepsy, it means that you have had more than one unexplained fit, or seizure. A seizure is a short episode of symptoms caused by a burst of abnormal electrical activity in your brain. Different parts of the brain control different functions of your body, so the symptoms that occur during a seizure will depend on where the abnormal burst of electrical activity occurs. Symptoms that may occur during a seizure can affect your muscles, sensations, behaviour, emotions, consciousness, or a combination of these. The seizures can be prevented in most people by suitable antiepileptic medication. Phenytoin is a commonly used medicine. It works by stabilising the electrical activity of your brain, which prevents the seizures from occurring.
Phenytoin is also prescribed as a treatment for severe burning or stabbing pains in the face, a nerve pain called trigeminal neuralgia. This is because it can modify some types of pain. If you have been given phenytoin for this reason, ask your doctor if you have questions about your treatment.
Before taking phenytoin
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you (or your child if you are their carer) start taking phenytoin it is important that your doctor knows:
Si está embarazada, esperando un bebé o en período de lactancia.
Si tiene algún problema con el funcionamiento de su hígado.
Si padece un raro trastorno sanguíneo hereditario llamado porfiria.
Si alguna vez ha tenido una reacción alérgica a un medicamento.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que pueda adquirirse sin receta, así como medicamentos a base de plantas y complementarios.
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How to take phenytoin
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about phenytoin and will provide you with a full list of the side-effects which you may experience from taking it.
Take phenytoin exactly as your doctor tells you to. Your dose will be printed on the label of the pack to remind you about what the doctor said. It is usual to start treatment on a low dose, and then for the dose to be increased gradually to a regular maintenance dose.
It is important you try to take your doses at the same times each day. Having a routine will help you to remember to take your doses regularly. Although phenytoin can be taken before a meal, it is better taken during or straight after a meal.
If you are taking phenytoin chewable tablets (Epanutin® Infatabs), you can chew the tablet to help you swallow or you can swallow the tablet in the usual way with a drink of water.
If you are taking phenytoin oral liquid medicine (Epanutin® suspension), make sure that you shake the bottle well before you measure out your dose.
Si olvida tomar una dosis, tómela en cuanto se acuerde. Si cuando se acuerde, es casi la hora de la siguiente dosis, tómese la siguiente dosis cuando corresponda pero omita la dosis olvidada. No tome dos dosis juntas para compensar la dosis olvidada.
Aproveche al máximo su tratamiento
Cuando empiece un nuevo tratamiento para la epilepsia puede haber un cambio en el número o tipo de crisis que experimente. Su médico le informará al respecto.
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. You will need to have blood tests from time to time.
Durante el tratamiento de la epilepsia existe un pequeño riesgo de que se produzcan cambios de humor, pensamientos angustiosos y sentimientos suicidas. Si esto ocurre, debe comunicárselo inmediatamente a su médico.
Las personas con epilepsia deben dejar de conducir al principio. Su médico le indicará cuándo puede volver a conducir. Normalmente será después de un año sin crisis.
Different formulations and brands of phenytoin can act in a slightly different way in your body. Because of this, it is important that you continue to take phenytoin from the same manufacturer as you have had before. So, each time you collect a prescription, check to make sure your supply looks the same and that the brand name is the same. If you are unsure, or if you have any questions about your prescription, please ask your pharmacist to check it for you.
If you drink alcohol, ask your doctor for advice. Your doctor may advise you not to drink alcohol while you are on this medicine because it can alter the amount of phenytoin in your body.
If you buy any medicines, check with a pharmacist that they are suitable for you to take with your antiepileptic medication. Some indigestion remedies can interfere with the amount of phenytoin in your body.
Many antiepileptic medicines can harm an unborn child. If you are a woman, make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. Phenytoin can make oral contraceptives less effective. Your doctor will advise you on other types of contraception such as an intra-uterine device (IUD) and barrier methods. You should use effective contraception throughout treatment with phenytoin and for one month after stopping. If you want to have a family, discuss this with your doctor so that you can be given advice from a specialist before you become pregnant.
You need to take phenytoin regularly every day. Do not stop taking it unless your doctor tells you to stop. Stopping treatment suddenly can cause problems and your doctor will want you to reduce your dose gradually if this becomes necessary.
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Can phenytoin cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with phenytoin. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common phenytoin side-effects | ¿Qué puedo hacer si me ocurre esto? |
Sentirse mal (náuseas) o estar enfermo (vómitos) | Comidas sencillas: evite las comidas ricas o picantes. |
Estreñimiento | Seguir una dieta equilibrada y beber mucha agua al día. |
Feeling dizzy or sleepy; eyesight problems such as double vision | No conduzca ni utilice herramientas o máquinas mientras esté afectado |
Dolor de cabeza | Bebe mucha agua y pide a tu farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza persisten, informe a su médico. |
Erupción | Let your doctor know about this as soon as possible, even if it is mild |
Difficulty sleeping, numb or tingling feelings, lack of appetite, sore or swollen gums, facial changes, acne, increased hair growth, slurred speech, lack of concentration, and feeling confused, nervous, unsteady or shaky | Si alguno de estos síntomas le resulta molesto, comuníqueselo a su médico |
Important: your doctor will discuss with you the possibility that phenytoin can cause blood and skin disorders. Although these occur less commonly than the side-effects listed above, it is important that you contact your doctor straightaway if you experience any of the following symptoms:
A high temperature (fever), sore throat or swollen glands.
Una erupción cutánea grave.
Úlceras bucales.
Hematomas o hemorragias inexplicables.
If you experience any other symptoms which you think may be due to phenytoin, speak with your doctor or pharmacist for further advice.
How to store phenytoin
Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
No tome nunca más de la dosis prescrita. Si sospecha que usted u otra persona ha tomado una sobredosis de este medicamento, acuda al servicio de urgencias de su hospital. Llévese el envase, aunque esté vacío.
Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.
Si va a someterse a una operación o a un tratamiento dental, comunique a la persona que lleve a cabo el tratamiento qué medicamentos está tomando.
No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.
Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.
MHRA - Notificación de reacciones adversas
Notifique a la Agencia Reguladora de Medicamentos y Productos Sanitarios las sospechas de efectos secundarios de medicamentos, vacunas, cigarrillos electrónicos, incidentes con productos sanitarios o productos defectuosos o falsificados para garantizar un uso seguro y eficaz.
Lecturas complementarias y referencias
- Manufacturer's PIL, Phenytoin sodium 100 mg film-coated tablets; Aurobindo Pharma - Milpharm Ltd, The electronic Medicines Compendium. Dated September 2022.
- Medicamentos BNF completa 89ª edición; Asociación Médica Británica y Real Sociedad Farmacéutica de Gran Bretaña, Londres.
Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
Fecha de la próxima revisión: 1 de enero de 2027
2 Ene 2024 | Última versión

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