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Duloxetine for mood and nerve disorders

Cymbalta, Depalta, Duciltia

The brands of duloxetine called Cymbalta®, Depalta® and Duciltia® are prescribed for mood and nerve disorders. You may also be prescribed generic duloxetine capsules; 30 mg and 60 mg capsules are prescribed for mood and nerve disorders.

Each time you collect a prescription from the pharmacy make sure the strength of your medicine (30 mg or 60 mg) is the same as before. Ask your pharmacist if you have any questions or concerns.

Informe a su médico si nota que empeora o si experimenta algún efecto secundario molesto.

Duloxetine can make you feel dizzy or sleepy. If this happens, do not drive and do not use tools or machines.

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About duloxetine for mood and nerve disorders

Tipo de medicamento

A serotonin and noradrenaline reuptake inhibitor

Utilizado para

Depression; anxiety disorder; pain caused by nerve damage in people with diabetes

También llamado

Cymbalta®; Depalta®; Duciltia®

Disponible como

Cápsulas

Duloxetine is prescribed for the treatment of some mood and nerve disorders. These include depression, some anxiety disorders and also a certain type of pain caused by nerve damage in people with diabetes, called diabetic neuropathy.

People with depression have a consistently low mood and other symptoms severe enough to interfere with normal day-to-day activities. Depression can develop for no apparent reason, or it may be triggered by a life event such as a relationship problem, bereavement or illness. Duloxetine is thought to work by regulating the levels of certain chemicals in your brain (called serotonin and noradrenaline/norepinephrine) which may be involved in causing the symptoms of depression.

The symptoms of diabetic neuropathy and some anxiety disorders can also be improved by controlling the levels of serotonin and noradrenaline. If you have been prescribed duloxetine for either of these conditions, it will help to ease your symptoms of pain or anxiety.

Duloxetine is also prescribed for treating urinary symptoms, although a different brand and strength of capsule are used. There is a separate medicine leaflet called Duloxetine for urinary symptoms, giving more information about duloxetine when used for this condition.

Before taking duloxetine

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking duloxetine it is important that your doctor knows:

  • Si está embarazada, esperando un bebé o en período de lactancia.

  • If you have problems with the way your liver works, or with the way your kidneys work.

  • Si padece una enfermedad cardiaca.

  • Si tiene un aumento de la presión ocular (llamado glaucoma).

  • Si tiene la tensión alta.

  • If you have ever had 'high' moods, such as mania in bipolar disorder.

  • Si alguna vez ha tenido un ataque (convulsión).

  • If you have a blood disorder that increases your risk of bleeding.

  • Si toma o utiliza otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que pueda adquirirse sin receta, así como medicamentos a base de plantas y complementarios.

  • Si alguna vez ha tenido una reacción alérgica a un medicamento.

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How to take duloxetine

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about duloxetine and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take duloxetine exactly as your doctor tells you to. The usual dose is one capsule of either 30 mg or 60 mg daily. When starting duloxetine, your doctor may give you the lower strength of capsules to begin with, and then increase the strength as you go on.

  • Try to take your doses at the same time of day each day, as this will help you to remember to take your doses regularly. You can take duloxetine either before or after meals. Swallow the capsule whole with a drink of water to help you to swallow it.

  • If you forget to take a dose at your usual time, take it when you remember. If you do not remember until the following day then leave out the forgotten dose and take your next dose when it is due. Do not take two doses together to make up for a missed dose.

Aproveche al máximo su tratamiento

  • Procure acudir a las citas periódicas con su médico. Así podrá comprobar su evolución y revisar su tratamiento.

  • You may feel that duloxetine is not helping you straightaway. If you are taking duloxetine for depression or anxiety, it can take a week or two before the effect builds up and 2-4 weeks before you feel the full benefit. If you are taking duloxetine for nerve pain damage, it can take several weeks before you feel better. Do not stop taking the capsules after a week or so, thinking they are not working.

  • If you are taking duloxetine for depression, you should expect that a normal course of treatment will last for around six months after your symptoms have eased. There are several types of antidepressants and they differ in their possible side-effects - if you find that duloxetine does not suit you then let your doctor know, as another may be found that will.

  • If you drink alcohol, ask your doctor for advice about drinking while you are on duloxetine. Drinking alcohol can increase the risk of unwanted effects from duloxetine, such as dizziness and blurred vision.

  • If you buy any medicines, check with a pharmacist that they are suitable to take with duloxetine. This is because some herbal medicines (such as St John's wort) can increase the risk that you will experience unwanted effects.

  • If you are having an operation or dental treatment, please tell the person carrying out the treatment that you are taking duloxetine.

  • Keep taking duloxetine until your doctor tells you otherwise. Your treatment is likely to last for a number of months. Stopping suddenly can cause symptoms such as headache, sickness, anxiety, dizziness, shakiness and sleeping problems. Your doctor will reduce your dose gradually over a week or two to reduce the risk of these sorts of problems.

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Can duloxetine cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the common ones associated with duloxetine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common duloxetine side-effects (these affect more than 1 in 10 people)

¿Qué puedo hacer si me ocurre esto?

Sensación de malestar (náuseas)

Coma comidas sencillas - evite los alimentos ricos o picantes

Boca seca

Prueba a mascar chicle sin azúcar o chupar caramelos sin azúcar

Estreñimiento

Intenta seguir una dieta equilibrada y beber varios vasos de agua al día.

Common duloxetine side-effects (these affect fewer than 1 in 10 people)

¿Qué puedo hacer si me ocurre esto?

Blurred vision; feeling tired, dizzy or sleepy

Do not drive and do not use tools or machines while affected. Avoid alcohol

Diarrea

Beber mucha agua para reponer los líquidos perdidos

Dolor de cabeza

Bebe mucha agua y pide a tu farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza persisten, informe a su médico.

Lack of appetite, indigestion, stomach pain, facial flushing, increased blood pressure, difficulty sleeping, feeling anxious, skin tinglings, feeling shaky, reduced interest in sex, increased sweating

Coméntelo con su médico si alguno le resulta molesto

Important: if you develop any depressing or distressing thoughts or ideas, you should let your doctor know about this as soon as possible. When this medicine is prescribed for people with depression or anxiety, it can increase the risk of suicidal thoughts, particularly when the treatment is first started.

En raras ocasiones, los medicamentos que afectan al nivel de serotonina en el cerebro pueden hacer que aumente demasiado y causar problemas. El riesgo es mayor si está tomando otro medicamento con este efecto (como un antidepresivo). Busque atención médica si presenta cualquier combinación de las siguientes:

  • Rigidez muscular o movimientos bruscos.

  • Latidos del corazón inusualmente rápidos.

  • Temperatura alta (fiebre).

  • Sentirse enfermo (náuseas) o estar enfermo (vómitos), diarrea.

  • Delirios o visiones (alucinaciones).

Si experimenta cualquier otro síntoma que considere que puede deberse al medicamento, consulte a su médico o farmacéutico.

How to store duloxetine

  • Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.

  • Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.

Información importante sobre todos los medicamentos

Información importante sobre todos los medicamentos

No tome nunca más de la dosis prescrita. Si sospecha que usted u otra persona ha tomado una sobredosis de este medicamento, acuda al servicio de urgencias de su hospital. Llévese el envase, aunque esté vacío.

Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.

No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.

Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.

Informar de los efectos secundarios de un medicamento o vacuna

Si experimenta efectos secundarios, puede notificarlos en línea a través del sitio web de la Tarjeta Amarilla.

Lecturas complementarias y referencias

Historia del artículo

La información de esta página ha sido redactada y revisada por médicos cualificados.

  • Fecha de la próxima revisión: 24 de agosto de 2027
  • 17 ago 2024 | Última versión

    Última actualización

    Michael Stewart, MRPharmS

    Revisado por expertos

    Sid Dajani
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