Duloxetine for urinary symptoms
Yentreve
Peer reviewed by Sid DajaniLast updated by Michael Stewart, MRPharmSLast updated 23 Aug 2024
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The brand of duloxetine called Yentreve® is prescribed for women with stress incontinence. Take one capsule twice daily, in the morning and late afternoon. You may be given generic duloxetine capsules; 20 mg and 40 mg capsules are prescribed for stress incontinence.
Remember to do the exercises you have been given to strengthen your pelvic floor muscles.
Each time you collect a new supply of capsules, make sure the strength (20 mg or 40 mg) is the same as you have taken previously. If not, please speak with your pharmacist who will advise you.
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About duloxetine for urinary symptoms
Tipo de medicamento | A serotonin and noradrenaline reuptake inhibitor |
Utilizado para | Symptoms of stress incontinence in women |
También llamado | Yentreve® |
Disponible como | Cápsulas |
Stress incontinence is the most common form of incontinence. It means you pass urine with things like coughing, sneezing or exercise. It happens when the pelvic floor muscles that support your bladder are weakened. Childbirth is a common reason for a weak pelvic floor. The main treatment for stress incontinence is pelvic floor exercises. Surgery to tighten or support your bladder outlet can also help.
Duloxetine may be advised if pelvic floor exercises alone are not helping to treat your stress incontinence. It is usually advised in women who do not want to undergo surgery, or in women who have health problems that may mean that surgery is unsuitable.
Duloxetine is thought to work by interfering with certain chemicals (called serotonin and noradrenaline) that are used within the nerves that send messages to your pelvic floor muscles. This helps the muscles around the bladder outlet to contract more strongly, and this in turn controls the flow of urine and helps to prevent any leakage.
Duloxetine is also prescribed for the treatment of some mood and nerve disorders, although a different brand and strength of capsule are used. There is a separate medicine leaflet called Duloxetine for mood and nerve disorders which gives more information about duloxetine when it is used for this type of condition.
Before taking duloxetine
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking duloxetine it is important that your doctor knows:
Si está embarazada, esperando un bebé o en período de lactancia.
Si tiene algún problema con el funcionamiento del hígado o de los riñones.
Si padece una enfermedad cardiaca.
Si tiene un aumento de la presión ocular (llamado glaucoma).
Si tiene la tensión alta.
If you have ever had 'high' moods, such as mania in bipolar disorder.
Si alguna vez ha tenido un ataque (convulsión).
If you have a blood disorder that increases your risk of bleeding.
Si toma o utiliza otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que pueda adquirirse sin receta, así como medicamentos a base de plantas y complementarios.
Si alguna vez ha tenido una reacción alérgica a un medicamento.
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How to take duloxetine
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about duloxetine and will provide you with a full list of the side-effects which you may experience from taking it.
Take duloxetine exactly as your doctor tells you to. The usual dose is one 40 mg capsule twice daily (in the morning and late afternoon). If you are taking duloxetine for the first time, your doctor may give you the lower 20 mg strength capsule for a couple of weeks - this is to help avoid any unwanted symptoms when you first take duloxetine.
Try to take your doses at the same times of day each day, as this will help you to remember to take your doses regularly. You can take duloxetine either before or after meals. Take the capsules with a drink of water to help you to swallow.
If you forget to take a dose at your usual time, take it when you remember. However, if it is nearly time to take your next dose when you remember then leave out the forgotten dose and take your next dose when it is due. Do not take two doses together to make up for a missed dose.
Aproveche al máximo su tratamiento
Procure acudir a las citas periódicas con su médico. Así podrá comprobar su evolución y revisar su tratamiento.
Remember to do the exercises you have been given to strengthen your pelvic floor muscles. This is important because the majority of people with stress incontinence are much improved with these exercises.
If you have been advised to reduce your weight, try to stick to the advice you have been given about your diet. Losing even a modest amount of weight can help to improve your symptoms.
Smoking can cause coughing which can aggravate your symptoms. It would help to not smoke. If you are a smoker and you need help to quit, ask your doctor or pharmacist for advice.
Drinking alcohol can increase the risk of unwanted effects from duloxetine, such as dizziness and blurred vision.
If you buy any medicines, check with a pharmacist that they are suitable to take with duloxetine. This is because some herbal medicines (such as St John's wort) can increase the chance that you will experience unwanted effects.
If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking duloxetine.
Keep taking duloxetine until your doctor tells you otherwise. Stopping suddenly can cause problems and your doctor may want you to reduce your dose gradually when this becomes necessary.
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Can duloxetine cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the common ones associated with duloxetine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common duloxetine side-effects (these affect more than 1 in 10 people) | ¿Qué puedo hacer si me ocurre esto? |
Sensación de malestar (náuseas) | Coma comidas sencillas - evite los alimentos ricos o picantes |
Boca seca | Prueba a mascar chicle sin azúcar o chupar caramelos sin azúcar |
Estreñimiento | Intenta seguir una dieta equilibrada y beber varios vasos de agua al día. |
Common duloxetine side-effects (these affect fewer than 1 in 10 people) | ¿Qué puedo hacer si me ocurre esto? |
Blurred vision, feeling tired, dizzy or sleepy | Do not drive and do not use tools or machines while affected. Avoid alcohol |
Diarrea | Beber mucha agua para reponer los líquidos perdidos |
Dolor de cabeza | Ensure you are drinking the recommended amount of fluids each day. Ask your pharmacist to recommend a suitable painkiller. If the headaches continue, let your doctor know |
Lack of appetite, indigestion, stomach pain, flushing, increased blood pressure, difficulty sleeping, feeling anxious, skin tinglings, feeling shaky, reduced interest in sex, increased sweating | Coméntelo con su médico si alguno le resulta molesto |
Important: if you develop any depressing or distressing thoughts or ideas, you should let your doctor know about this as soon as possible. When this medicine is prescribed for people with depression or anxiety, it can increase the risk of suicidal thoughts, particularly when the treatment is first started.
En raras ocasiones, los medicamentos que afectan al nivel de serotonina en el cerebro pueden hacer que aumente demasiado y causar problemas. El riesgo es mayor si está tomando otro medicamento con este efecto (como un antidepresivo). Busque atención médica si presenta cualquier combinación de las siguientes:
Rigidez muscular o movimientos bruscos.
Latidos del corazón inusualmente rápidos.
Temperatura alta (fiebre).
Sentirse enfermo (náuseas) o estar enfermo (vómitos), diarrea.
Delirios o visiones (alucinaciones).
Si experimenta cualquier otro síntoma que crea que puede deberse a las cápsulas, consulte a su médico o farmacéutico.
How to store duloxetine
Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
No tome nunca más de la dosis prescrita. Si sospecha que usted u otra persona ha tomado una sobredosis de este medicamento, acuda al servicio de urgencias de su hospital. Llévese el envase, aunque esté vacío.
Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.
No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.
Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.
Informar de los efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede notificarlos en línea a través del sitio web de la Tarjeta Amarilla.
Lecturas complementarias y referencias
- Manufacturer's PIL, Yentreve® 20 mg and 40 mg hard gastro-resistant capsules; Eli Lilly and Company Ltd, The electronic Medicines Compendium. Dated June 2024.
- Medicamentos BNF completa 89ª edición; Asociación Médica Británica y Real Sociedad Farmacéutica de Gran Bretaña, Londres.
Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
Fecha de la próxima revisión: 24 de agosto de 2027
23 Aug 2024 | Latest version

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