Co-codamol para aliviar el dolor
Solpadol, Zapain
Peer reviewed by Dr Colin Tidy, MRCGPLast updated by Michael Stewart, MRPharmSLast updated 10 Jan 2024
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This medicine contains an opioid painkiller (codeine). There is a serious risk of addiction when taking this medicine, especially if used long-term. The Medicines and Healthcare products Regulatory Agency (MHRA) has issued new guidance for people prescribed an opioid painkiller. If you have any questions or concerns about taking opioids safely please speak with your doctor or a pharmacist.
If you have bought co-codamol from a pharmacy you should not take it for more than three days in a row. If you are still in pain after this time ask your doctor or a pharmacist for advice.
Co-codamol contains both paracetamol and codeine. Do not take any other preparation which contains paracetamol while you are taking co-codamol.
The usual dose for an adult is one or two co-codamol tablets/capsules every 4-6 hours if needed. Do not take more than two tablets/capsules at a time or more than eight tablets/capsules in 24 hours.
The most common side effects of co-codamol are feeling sleepy and dizzy.
Co-codamol is likely to affect your reactions and your ability to drive. Do not drive until you know how it affects you.
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About co-codamol
Tipo de medicamento | Un analgésico combinado |
Utilizado para | Alivio del dolor |
También llamado (UK) | Codipar®; Emcozin®; Panadol Ultra®; Solpadol®; Solpadeine Max®; Tylex®; Zapain® |
También llamado (EE.UU.) | Acetaminophen with codeine; Codrix®; Tylenol® with codeine |
Disponible como | Capsules, tablets and effervescent tablets |
What is co-codamol used for?
Co-codamol is a type of painkiller that contains paracetamol and codeine. It is given to relieve short-lasting painful conditions where paracetamol alone is not sufficient.
There are three different strengths of co-codamol available, one of which can be bought without a prescription at a pharmacy. The amount of paracetamol in the three different strengths is the same (500 mg), but the amount of codeine differs and this determines the strength of the preparation.
The three main tablet strengths are: 8 mg/500 mg, 15 mg/500 mg, and 30 mg/500 mg, where the first number relates to how much codeine is in the tablet, and the second is the amount of paracetamol present.
Combination painkillers like co-codamol can reduce how many tablets you take, but they may not give the best pain relief. It’s harder to adjust the dose without increasing side effects, so many doctors prefer not to prescribe them.
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Side effects of co-codamol
Common side effects of co-codamol are:
Sensación de malestar (náuseas).
Estar enfermo (vómitos).
Estreñimiento.
Feeling sleepy or drowsy.
Boca seca.
Sudando.
Dolor de estómago.
Encontrará una lista completa en el prospecto del fabricante que acompaña al medicamento.
The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any side effects continue or become troublesome.
How to manage co-codamol side effects
Common co-codamol side effects | ¿Qué puedo hacer si me ocurre esto? |
Feeling sick or being sick | Comidas sencillas: evite los alimentos ricos o picantes. |
Estreñimiento | Seguir una dieta equilibrada y beber mucha agua. |
Sensación de sueño o somnolencia | Si esto ocurre, no conduzca ni utilice herramientas o máquinas. No bebas alcohol |
Boca seca, sudoración, dolor de barriga (puede deberse a un espasmo de las vías biliares). | Hable con su médico en caso de molestias |
Si experimenta cualquier otro síntoma que crea que puede deberse al medicamento, coméntelo con su médico o farmacéutico para que le aconsejen.
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Who should not take co-codamol?
Some medicines aren’t safe for people with certain health conditions, or may need to be used with extra care. So before you start taking co-codamol, make sure your doctor or pharmacist knows:
Si está embarazada o en periodo de lactancia.
Si tiene algún problema con el funcionamiento del hígado o de los riñones.
Si tiene problemas de próstata o dificultades para orinar.
Si tiene algún problema respiratorio, como asma o enfermedad pulmonar obstructiva crónica (EPOC).
Si le han dicho que tiene la tensión baja o un ritmo cardiaco anormal.
Si tiene problemas de tiroides o glándulas suprarrenales.
Si padece epilepsia.
Si tiene cálculos biliares o algún problema en la vesícula o el conducto biliar.
Si ha estado estreñido durante más de una semana o tiene un problema inflamatorio intestinal.
Si padece una enfermedad que causa debilidad muscular, llamada miastenia gravis.
Si ha sufrido recientemente un traumatismo craneoencefálico grave.
Si alguna vez ha sido dependiente de las drogas o el alcohol.
Si alguna vez ha tenido una reacción alérgica a un medicamento.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que pueda adquirirse sin receta, así como medicamentos a base de plantas y complementarios.
How to take co-codamol
Read the information leaflet in the pack before you start. It explains how co-codamol works and lists possible side effects.
Take co-codamol exactly as advised by your doctor or pharmacist. Adults usually take 1-2 tablets every 4-6 hours if needed.
Leave at least 4 hours between doses.
Don’t take more than 2 tablets at once or 8 tablets in 24 hours.
Swallow tablets/capsules with water. If you have effervescent tablets, dissolve them in a small glass of water first.
You can take co-codamol with or without food, but taking it after food may help prevent feeling sick.
If you miss a dose, just take one when you next need it. Do not double up to make up for a missed dose.
Aproveche al máximo su tratamiento
You can take over-the-counter co-codamol for up to 3 days. If your pain continues or the medicine doesn’t help, speak to a doctor or pharmacist.
Using co-codamol often for headaches can actually cause more headaches (medication-overuse headaches), even at normal doses. Do not use painkillers for headaches for more than 2 days in a row or 2 days a week. Get advice if you’re worried about this.
Do not take any other paracetamol-containing medicines while using co-codamol. Check labels or ask a pharmacist to be safe.
Avoid alcohol while taking co-codamol, as codeine increases the risk of alcohol-related side effects.
Co-codamol is usually only given for short-term use because stopping it after long-term use can cause withdrawal symptoms (for example, restlessness, irritability). If you’ve been taking it for a while, your doctor may reduce your dose gradually.
Long-term use of codeine can lead to tolerance, meaning it becomes less effective.
Never take more than the recommended dose. If you think you or someone else has taken too much, go to A&E immediately, even if you feel fine, because an overdose can seriously harm the liver. Bring the medicine container with you.
Tell your doctor, dentist, or surgeon that you are taking co-codamol if you are having any operation or dental treatment.
When buying any new medicines, always check with a pharmacist that they are safe to take with co-codamol.
How to store co-codamol
Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
No tome nunca más de la dosis prescrita. Si sospecha que usted u otra persona ha tomado una sobredosis de este medicamento, acuda al servicio de urgencias de su hospital. Llévese el envase, aunque esté vacío.
Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.
No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.
Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.
MHRA - Notificación de reacciones adversas
Notifique a la Agencia Reguladora de Medicamentos y Productos Sanitarios las sospechas de efectos secundarios de medicamentos, vacunas, cigarrillos electrónicos, incidentes con productos sanitarios o productos defectuosos o falsificados para garantizar un uso seguro y eficaz.
Preguntas más frecuentes
How long does it take for co-codamol to work?
Co-codamol usually starts to work within 30 to 60 minutes. Once it starts working, co-codamol can provide pain relief for around 4 to 6 hours.
Can you drink alcohol on co-codamol?
No, you should not drink alcohol while taking co-codamol. Mixing alcohol with co-codamol can increase drowsiness, slow your reactions, and make you feel very unwell.
You should wait until the co-codamol is fully out of your system - usually at least 24 hours after your last dose - before having alcohol.
Is it safe to take co-codamol during pregnancy?
Co-codamol is not usually recommended during pregnancy because it contains codeine, which may affect your baby’s breathing or cause withdrawal symptoms if used regularly or late in pregnancy.
Can you take co-codamol with ibuprofen?
Yes, it is generally safe to take co-codamol with ibuprofen. They work in different ways, so taking them together can provide better pain relief. Always take co-codamol as directed and take ibuprofen with food or water to reduce stomach upset.
Can you buy co-codamol over the counter?
Yes, you can buy low-strength co-codamol (8/500 mg) over the counter in the UK. Stronger doses require a prescription from a doctor.
Lecturas complementarias y referencias
- Manufacturer's PIL, Co-codamol 8 mg/500 mg tablets; Zentiva, The electronic Medicines Compendium. Dated February 2023.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
Próxima revisión prevista: 9 de enero 2027
10 Ene 2024 | Última versión

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