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Hidromorfona para el dolor por cáncer

Palladone

This medicine is an opioid painkiller. There is a serious risk of addiction when taking this medicine, especially if used long-term. The Medicines and Healthcare products Regulatory Agency (MHRA) has issued nuevas pautas para personas a las que se les ha recetado un analgésico opioide. Si tiene alguna pregunta o inquietud sobre el uso seguro de opioides, por favor hable con su médico o farmacéutico.

Hydromorphone eases severe pain associated with cancer.

The capsules can be swallowed whole with a drink of water, or opened and the contents sprinkled on to some soft food such as yoghurt.

The most common side-effects are constipation, drowsiness and feeling sick (nausea). Your doctor may prescribe medicines for you to take with hydromorphone to help with some of these side-effects.

De un vistazo

  • Hydromorphone is a strong opioid painkiller prescribed for severe cancer pain.

  • It is available as quick-acting or modified-release capsules.

  • Tell your doctor about existing health conditions, especially liver, kidney, or breathing problems.

  • Always take hydromorphone exactly as your doctor instructs.

  • Do not suddenly stop taking hydromorphone without medical advice.

  • Common side-effects include feeling sick, dizziness, drowsiness, and constipation.

  • Seek immediate medical help if you experience signs of overdose like severe sleepiness or breathing difficulties.

About hydromorphone

Tipo de medicamento

Analgésico opioide fuerte

Usado para

Pain relief in adults with cancer

También llamado

Palladone®

Disponible como

Capsules, and modified-release capsules

Strong opioids are medicines used to treat severe pain. Hydromorphone is a type of strong opioid (sometimes called an opiate) used to treat pain caused by cáncer. It works on your nervous system and brain to reduce the amount of pain you feel.

Hydromorphone is taken by mouth as a capsule. There are two types of capsule available: quick-acting capsules (Palladone®) and modified-release capsules (Palladone® SR). Modified-release capsules release the hydromorphone they contain more slowly than the quick-acting capsules do. This provides longer and more even pain relief.

Before taking hydromorphone

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking hydromorphone it is important that your doctor knows:

  • Si estás embarazada, intentando tener un bebé o amamantando.

  • Si tienes problemas de hígado o riñón.

  • Si tienes problemas de próstata o alguna dificultad para orinar.

  • Si tienes algún problema respiratorio, como asma o enfermedad pulmonar obstructiva crónica (EPOC).

  • If you have been told you have low blood pressure (hypotension).

  • If you have any problems with your thyroid, pancreas, or adrenal glands.

  • Si tienes epilepsia.

  • Si tienes un problema con tu conducto biliar.

  • Si has estado estreñido por más de una semana o tienes un problema inflamatorio intestinal.

  • Si tienes una condición que causa debilidad muscular, llamada miastenia gravis.

  • If you have a mental health problem called toxic psychosis.

  • Si recientemente has tenido una lesión grave en la cabeza.

  • Si alguna vez has sido dependiente de las drogas o el alcohol.

  • Si alguna vez has tenido una reacción alérgica a un medicamento.

  • Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.

How to take hydromorphone

  • Before you start taking the capsules, read the manufacturer's printed information leaflet from inside the pack. The manufacturer's leaflet will give you more information about hydromorphone and a full list of the side-effects which you may experience from taking it.

  • Take hydromorphone exactly as your doctor tells you to. If you have been prescribed the quick-acting capsules (Palladone®), you will be asked to take a dose every four hours. The modified-release capsules (Palladone® SR) are taken twice a day, 12 hours apart.

  • There are different strengths of both types of hydromorphone capsule, so each time you collect a prescription check to make sure it is the strength you are expecting.

  • You can swallow the capsules whole with a drink of water, or alternatively, open them and sprinkle the contents on to some soft food, such as yoghurt. Do not dissolve or chew the contents of the capsule as this may release all the medicine at once and cause side-effects.

  • You can take hydromorphone before or after food.

  • If you forget to take a dose, take it as soon as you remember and then continue as before. If it is nearly time for your next dose, leave out the forgotten dose and take the next dose when it is due. Do not take two doses together to make up for a forgotten dose. If you are taking quick-acting capsules do not take more than one dose every four hours.

Obteniendo el máximo de tu tratamiento

  • Ask your doctor for advice before drinking alcohol while you are on this medicine. Your doctor may recommend you do not drink alcohol while you are on hydromorphone because it increases the possibility of side-effects such as feeling dizzy and sleepy.

  • If you are a driver, please be aware that hydromorphone is likely to affect your reactions and ability to drive. It is an offence to drive while your reactions are impaired. Even if your driving ability is not impaired, should you drive, you are advised to carry with you some evidence that the medicine has been prescribed for you - a repeat prescription form or a patient information leaflet from the pack is generally considered suitable.

  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking hydromorphone as a painkiller.

  • If you buy any medicines, check with a pharmacist that they are suitable for you to take with hydromorphone. Many other medicines have similar side-effects to hydromorphone, and taking them together will increase the risk of these.

  • If you are planning a trip abroad, you are advised to carry a letter with you from your doctor to explain that you have been prescribed hydromorphone. This is because hydromorphone is classed as a 'controlled drug' and is subject to certain restrictions.

  • Continue to take hydromorphone unless your doctor tells you otherwise. Stopping suddenly will cause your pain to return, and it can also cause you to feel agitated, anxious, and sweaty. If you need to stop taking hydromorphone your doctor will prescribe an alternative painkiller for you, or reduce your dose gradually.

Can hydromorphone cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with hydromorphone. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Común

hydromorphone side-effects

¿Qué puedo hacer si experimento esto?

Sentirse mal (náuseas) o estar enfermo (vómitos)

Stick to simple meals - avoid rich or spicy foods. Also, try taking your doses after food, as this may help

Shallow breathing

Informe a su médico sobre esto

Sentirse mareado, somnoliento o con sueño

Si esto ocurre, no conduzca y no utilice herramientas o máquinas. No consuma alcohol

Estreñimiento

Try to eat a well-balanced diet and drink plenty of water each day. If this continues to be a problem, speak with your doctor who may prescribe a laxative for you

Boca seca

Intenta masticar chicle sin azúcar o chupar caramelos sin azúcar

Other common side-effects include: feeling confused or disorientated, itching, sweating, mood changes, disturbed sleep, headache, difficulties passing urine, flushing, and rash

Si alguno de estos se vuelve problemático, hable con su médico

Importante: people taking opioid medicines, and their family and friends, should be aware of the risk of accidental overdose and know when to seek medical help. The risk is higher if you also take other medicines that make you feel drowsy. Signs you have taken too much medicine include:

  • Sintiéndose muy somnoliento o mareado.

  • Sentirse mal (náuseas) o estar enfermo (vómitos).

  • Dificultades para respirar.

  • Pérdida de conciencia.

If you have taken more morphine than you should or someone else accidentally swallows your medication, call for an ambulance and tell them the name of your medicine.

Si experimenta otros síntomas que cree que pueden deberse a este medicamento, hable con su médico o farmacéutico.

How to store hydromorphone

  • Mantenga todos los medicamentos fuera del alcance y la vista de los niños.

  • Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.

Información importante sobre todos los medicamentos

Información importante sobre todos los medicamentos

Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.

Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.

No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.

Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.

Informar efectos secundarios de un medicamento o vacuna

Si experimenta efectos secundarios, puede reportarlos en línea a través de Sitio web de Yellow Card.

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¿Inseguro sobre mezclar medicamentos?

Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.

Preguntas frecuentes

Can I take hydromorphone if I am pregnant or breastfeeding?

If you are pregnant, trying for a baby, or breastfeeding, it is important to let your doctor know before you start taking hydromorphone. Your doctor will need to consider this information to ensure the medicine is suitable for you.

Is it safe to drive while taking hydromorphone?

Hydromorphone is likely to affect your reactions and your ability to drive. It is an offence to drive if your reactions are impaired. Even if you feel your driving ability is not impaired, you should carry evidence that the medicine has been prescribed for you, such as a repeat prescription form or a patient information leaflet, in case you are stopped.

What should I do if I need to stop taking hydromorphone?

You should continue to take hydromorphone unless your doctor tells you otherwise. If you need to stop, your doctor will either prescribe an alternative painkiller or gradually reduce your dose. Stopping suddenly can cause your pain to return and may also lead to agitation, anxiety, and sweating.

What should I do if I experience constipation while taking hydromorphone?

Constipation is a common side-effect. You can try to eat a well-balanced diet and drink plenty of water daily to help. If constipation continues to be a problem, speak with your doctor, as they may be able to prescribe a laxative for you.

How should I store my hydromorphone capsules?

You should keep all medicines, including hydromorphone, out of the reach and sight of children. Store them in a cool, dry place, away from direct heat and light.

Lecturas adicionales y referencias

Sobre el autorVer biografía completa

Imagen del autor

Michael Stewart, MRPharmS

Gerente de Revisión de Folletos de Medicamentos – Contratista, Farmacéutico

BPharm (Hons), MRPharmS

Michael es un farmacéutico comunitario que ejerce en Midlands y South Yorkshire con más de 20 años de experiencia asesorando sobre medicamentos y condiciones médicas. Tiene una sólida formación en capacitación en atención médica, habiendo producido e impartido cursos de formación para equipos de farmacia y personal de entornos de atención residencial, incluidas enfermeras. También ha contribuido a juntas asesoras de farmacia para la gestión de condiciones de baja gravedad en la comunidad.

Acerca del revisor

Imagen del autor

Sid Dajani

Sultan Dajani se graduó en la Escuela de Farmacia de Londres en 1994 y se convirtió en el miembro más joven elegido para el consejo de la Sociedad Real de Farmacia desde su fundación en 1842.

Historial del artículo

La información en esta página está escrita y revisada por pares por clínicos calificados.

  • Próxima revisión: 23 de agosto de 2027
  • 24 Feb 2023 | Última versión

    Última actualización por

    Michael Stewart, MRPharmS

    Revisado por pares por

    Sid Dajani
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