Toxina botulínica tipo A para la migraña
Botox
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 19 Sept 2023
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Botulinum toxin type A is a specialist treatment for migraine.
To be eligible for this treatment you must have headaches for 15 or more days each month, with migraine headaches being on at least eight of these days.
It will be given by multiple injections into the muscles around your head and neck.
If you experience any difficulty swallowing, speaking, or breathing after the treatment, speak with your doctor immediately.
De un vistazo
Botulinum toxin type A is a neurotoxin used to prevent chronic migraine headaches.
It is given by injection into muscles around the head and neck.
To be eligible, you must have frequent headaches and have tried other migraine prevention medicines.
Injections are typically repeated every 12 weeks if the treatment is successful.
Common side-effects include pain at injection sites and muscle pain or weakness.
Seek immediate medical help if you experience difficulty swallowing, speaking, or breathing.
About botulinum toxin type A
Tipo de medicamento | A bacterial neurotoxin |
Usado para | To prevent headaches associated with chronic migraine in adults |
También llamado | Onabotulinumtoxin A (in US); Alluzience®; Azzalure®; Bocouture®; Botox®; Nuceiva®; Xeomin® |
Disponible como | Inyección |
Botulinum toxin type A is a protein substance which is produced by the bacterium Clostridium botulinum. It is a neurotoxin which means that it interferes with the way nerves work. To be eligible for this treatment you must have headaches for 15 or more days each month, with migraine headaches being on at least eight of these days. You must also have tried several other medicines to prevent migraine before this treatment is prescribed for you.
Botulinum toxin type A is thought to work in chronic migraine by relaxing muscles and by blocking the pain signals which are involved in the development of a migraine. These actions may have the effect of stopping a migraine headache from being triggered.
Botulinum toxin injections are also used for other reasons (including cosmetic purposes, muscle spasms, bladder problems, and excessive sweating). This leaflet does not cover the use of botulinum toxin type A in these ways.
Before being treated with botulinum toxin type A
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before being treated with botulinum toxin type A for migraine, make sure that your doctor knows:
Si estás embarazada, intentando tener un bebé o amamantando.
If you have an infection or any swelling near any of the areas that will be injected.
If you have any muscle problems, particularly any muscle weakness.
If you have ever had any difficulty in swallowing or with your breathing.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
Si alguna vez has tenido una reacción alérgica a un medicamento.
How you will be given botulinum toxin type A
Before you start the treatment, ask to read the manufacturer's printed information leaflet from inside the pack. It will give you more information about Botox® and will provide you with a full list of the side-effects which you may experience from having it.
You will be given botulinum toxin type A by a doctor who is trained in the use of this treatment. It will be injected into the muscles around your head and neck in several different places.
If the treatment proves successful for you, your doctor is likely to recommend that it is repeated every 12 weeks.
Obteniendo el máximo de tu tratamiento
If you are having an operation or dental treatment, tell the person carrying out the treatment that you have received botulinum toxin type A.
Can botulinum toxin type A cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with botulinum toxin type A. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects may occur following a treatment session even if you have been free from side-effects on previous treatments. You should speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common Botox® side-effects (these affect fewer than 1 in 10 people) | ¿Qué puedo hacer si experimento esto? |
Pain at the sites where you have been injected, neck and muscle pain or stiffness, muscle weakness, skin rash and itching | These should soon pass, but if any becomes troublesome, speak with your doctor |
Worsening of headache or migraine | Speak with your doctor about this |
Eyelid drooping or swelling, paralysis of the face | Speak with your doctor about this |
Importante: if you experience any difficulty swallowing, speaking, or breathing, speak with your doctor immediately or go to your local accident and emergency department straightaway.
If you experience any other symptoms which you think may be due to the treatment, speak with your doctor or pharmacist for further advice.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
If you buy any medicines, check with a pharmacist that they are safe to use alongside this treatment.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Sitio web de Yellow Card.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Preguntas frecuentes
What is botulinum toxin type A and how does it relate to Botox®?
Botulinum toxin type A is a protein substance derived from a bacterium which primarily interferes with nerve function. Botox® is one of several brand names, alongside others like Alluzience®, Azzalure®, Bocouture®, and Xeomin®, under which botulinum toxin type A is available for medical treatments, including chronic migraine.
Are there specific criteria I need to meet to be eligible for botulinum toxin type A treatment for migraine?
Yes, to be eligible for this treatment for migraine, you must experience headaches for 15 or more days each month, with migraine headaches occurring on at least eight of those days. Additionally, you need to have attempted and found insufficient several other migraine prevention medicines before this treatment will be considered.
How often will I need to receive botulinum toxin type A injections if they are effective for my migraines?
If the treatment is successful in managing your chronic migraines, your doctor will likely recommend that the injections are repeated approximately every 12 weeks.
Are there any specific situations where I should inform other healthcare professionals about my botulinum toxin type A treatment?
Yes, if you are planning to have an operation or dental treatment, it is important to inform the person carrying out the procedure that you have received botulinum toxin type A injections.
What should I do if I experience rare but serious side effects like difficulty swallowing or breathing after treatment?
If you experience any serious side effects such as difficulty swallowing, speaking, or breathing, you should seek immediate medical attention. Contact your doctor straightaway or go directly to your local accident and emergency department.
Lecturas adicionales y referencias
- Manufacturer's PIL, Botox® 50, 100 and 200 Allergan Units; AbbVie Ltd, The electronic Medicines Compendium. Dated April 2023.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
Sobre el autorVer biografía completa

Michael Stewart, MRPharmS
Gerente de Revisión de Folletos de Medicamentos – Contratista, Farmacéutico
BPharm (Hons), MRPharmS
Michael es un farmacéutico comunitario que ejerce en Midlands y South Yorkshire con más de 20 años de experiencia asesorando sobre medicamentos y condiciones médicas. Tiene una sólida formación en capacitación en atención médica, habiendo producido e impartido cursos de formación para equipos de farmacia y personal de entornos de atención residencial, incluidas enfermeras. También ha contribuido a juntas asesoras de farmacia para la gestión de condiciones de baja gravedad en la comunidad.
Acerca del revisor

Sid Dajani
Sultan Dajani se graduó en la Escuela de Farmacia de Londres en 1994 y se convirtió en el miembro más joven elegido para el consejo de la Sociedad Real de Farmacia desde su fundación en 1842.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Artículo también disponible en Inglés, Alemán, Español, Francés, Italiano, Portugués, Hindi, Hebreo, Árabe, y Sueco.
Próxima revisión: 18 de septiembre de 2026
19 Sept 2023 | Última versión

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