Doxepin capsules
Revisado por pares por Dr Colin Tidy, MRCGPÚltima actualización por Michael Stewart, MRPharmSLast updated 7 Ago 2023
Cumple con las directrices editoriales
- DescargarDescargar
- Compartir
- Language
- Discusión
- Versión en audio
Mantén tus citas regulares con tu médico. Esto es para que tu médico pueda verificar tu progreso.
Common side effects of doxepin include sleepiness, dry mouth, constipation, blurred vision, and dizziness.
Doxepin may make you feel sleepy. If this happens, do not drive and do not use tools or machines. Do not drink alcohol.
Tell your doctor if you experience any troublesome side effects.
En este artículo:
Video picks for Medicamentos para el sistema nervioso
Continúa leyendo abajo
About doxepin
Tipo de medicamento | Un antidepresivo tricíclico |
Usado para | The treatment of depression in adults aged 18 and over |
Disponible como | Cápsulas |
What is doxepin used for?
Volver al contenidoDoxepin is used for the treatment of depresión. It belongs to a group of medicines called antidepresivos tricíclicos.
Doxepin can help ease the symptoms of depression and is particularly helpful if you also have difficulty sleeping. It is thought to work by interfering with brain chemicals (called neurotransmitters) which may be involved in causing symptoms of depression.
The exact cause of depression is not known. It can develop for no apparent reason or it may be triggered by a life event such as a relationship problem, bereavement, or illness. With depression you have a consistently low mood and other symptoms severe enough to interfere with your normal day-to-day activities.
Continúa leyendo abajo
Side effects of doxepin
Volver al contenidoThe most common side effects of doxepin are:
Feeling sleepy or tired.
Boca seca.
Estreñimiento.
Visión borrosa.
Dizziness - especially when getting up from a sitting or lying position.
Dolor de cabeza.
Sentirse mal (náuseas).
Estar enfermo (vómitos).
Sudoración.
Encontrará una lista completa en el prospecto del fabricante que se suministra con su medicamento. Los efectos no deseados a menudo mejoran a medida que su cuerpo se adapta al nuevo medicamento, pero hable con su médico o farmacéutico si alguno de los siguientes persiste o se vuelve problemático.
How to manage doxepin side effects
Volver al contenidoCommon doxepin side effects | ¿Qué puedo hacer si experimento esto? |
Blurred vision, feeling sleepy or tired | Si esto ocurre, no conduzca y no utilice herramientas o máquinas. No consuma alcohol |
Boca seca | Intenta masticar chicle sin azúcar o chupar caramelos sin azúcar |
Estreñimiento | Try to eat a well-balanced diet containing plenty of fibre and drink plenty of water |
Feeling faint or light-headed, especially when getting up from a sitting or lying position | Levantarse más despacio puede ayudar. Si comienza a sentirse mareado, siéntese hasta que pase la sensación |
Dolor de cabeza | Pídale a su farmacéutico que le recomiende un analgésico adecuado |
Feeling sick or being sick, diarrhoea | Stick to simple meals - avoid rich or spicy foods. Drink plenty of water to replace lost fluids |
Sweating, flushing, difficulty in passing urine, increased appetite, feeling confused or anxious, disturbed sleep, lack of concentration, feeling shaky, itchy skin rash, weight changes, changes in sexual function, breast tenderness, changes in the way things taste, ringing in your ears, fast heartbeat | Si alguno de estos se vuelve problemático, hable con su médico para obtener consejo |
Importante: On rare occasions, medicines that affect the level of serotonin in the brain can cause it to go too high and cause problems. The risk is higher if you are taking more than one medicine with this effect. Seek medical attention if you develop any combination of the following:
Músculos rígidos o movimientos 'bruscos'.
Latidos del corazón inusualmente rápidos.
High temperature (fever), feeling sick (nausea) or being sick (vomiting), diarrhoea.
Sentirse delirante o ver visiones (alucinar).
Si experimenta otros síntomas que cree que pueden deberse al medicamento, hable con su médico o farmacéutico para obtener más consejos.
Continúa leyendo abajo
Who should not take doxepin?
Volver al contenidoSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking doxepin it is important that your doctor knows:
Si estás embarazada o amamantando.
Si tienes una glándula tiroides hiperactiva.
If you have any problems with the way your liver works, or the way your kidneys work.
If you have epilepsy or diabetes (diabetes mellitus).
If you have had problems with constipation over a long time.
Si tiene alguna dificultad para orinar, o si ha tenido problemas de próstata.
If you have a heart disorder or blood vessel disease.
If you have had a mental health problem - in particular, bipolar disorder or psychosis.
If you have increased pressure in your eyes (glaucoma).
If you have been told you have phaeochromocytoma - a tumour on your adrenal gland.
If you have porphyria - a rare inherited blood disorder.
If you are taking other medicines, including those available to buy without a prescription, as well as herbal and complementary medicines. This is especially important if you have recently taken a medicine for depression, known as a monoamine-oxidase inhibitor (MAOI).
Si alguna vez has tenido una reacción alérgica a un medicamento.
How to take doxepin capsules
Volver al contenidoRead the manufacturer's printed information leaflet from inside the pack. It will give you more information about doxepin and will provide you with a full list of the side effects which you may experience from taking it.
Doxepin can make you feel sleepy so your doctor may advise you to take a small dose when you first start taking it, and then to increase your dose gradually as your body gets used to it.
Doxepin is often prescribed once a day at bedtime, although it can also be taken two or three times a day. Your doctor will tell you which is right for you and the directions will be printed on the label of the pack to remind you what the doctor has said.
If you have any questions about how to take the capsules, ask your pharmacist for advice.
You can take doxepin before or after meals. Many people find if helps to swallow the capsule with a drink of water.
If you forget to take a dose, take it as soon as you remember unless your next dose is due. If it is nearly time for your next dose, then take the next dose when it is due but leave out the forgotten dose. Do not take two doses together to make up for a missed dose.
Obteniendo el máximo de tu tratamiento
Volver al contenidoIntenta mantener tus citas regulares con tu médico. Esto es para que tu médico pueda verificar tu progreso.
You may feel that doxepin is not working for you straightaway. It can take a week or two for the effect to build up, and 4-6 weeks before you feel the full benefit. It is important that you do not stop taking it thinking that it is not helping.
While you feel depressed, you may have distressing thoughts and think about harming yourself or ending your life. If this happens, it is very important that you tell your doctor about it straightaway.
If you drink alcohol, ask your doctor for advice. Your doctor is likely to recommend that you do not drink alcohol while you are on doxepin as it increases the risk of side effects, such as feeling sleepy.
There are several types of antidepressants - each type works in a slightly different way and can have different side effects. If you find that doxepin does not suit you then let your doctor know, as another antidepressant may be found that does.
Some people who take doxepin find that their skin becomes more sensitive to sunlight than usual. Do not use sunbeds and try to avoid strong sunlight until you know how your skin reacts. Use a sun cream with a high sun protection factor.
Your doctor may ask you to carry on taking doxepin even after you feel better. This is to help stop your symptoms from returning.
If you buy any medicines, check with a pharmacist that they are suitable for you to take. This is because a number of medicines can increase the risk of side effects from doxepin, including some painkillers, flu remedies and antihistamines.
If you have diabetes you may need to check your blood sugar (glucose) more frequently. This is because doxepin can alter the levels of sugar in your blood. Your doctor will advise you about this.
If you are due to have any medical treatment, tell the person carrying out the treatment that you are taking a tricyclic antidepressant, as they can interfere with some anaesthetics.
Continue to take doxepin unless your doctor tells you otherwise. Stopping treatment suddenly can sometimes cause problems and your doctor may want you to reduce your dose gradually if this becomes necessary.
How to store doxepin capsules
Volver al contenidoMantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Volver al contenidoInformación importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda de inmediato al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Yellow Card website.
Preguntas frecuentes
Volver al contenidoCan you get doxepin in the UK?
Yes, doxepin is available in the UK, but it’s not commonly prescribed compared to newer antidepressants. It may be used for depression, anxiety, or sometimes for sleep problems, but usually only when other options haven’t worked.
Is doxepin better than Xanax?
Doxepin and Xanax (alprazolam) work in very different ways. Doxepin is a tricyclic antidepressant and Xanax is a benzodiazepine, mainly prescribed short-term for anxiety or panic, as it can cause dependence if used for too long. Which is “better” depends on your condition and medical history.
How effective is doxepin for sleep?
Doxepin at low doses is sometimes prescribed to help with insomnia as it might improve sleep quality by reducing how often you wake up during the night and helping you stay asleep longer. It’s generally considered effective, especially for people who have trouble staying asleep, but it may not work for everyone.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Lecturas adicionales y referencias
- Manufacturer's PIL, Doxepin 25 mg and 50 mg Capsules; Marlborough Pharmaceuticals Ltd, The electronic Medicines Compendium. Dated May 2021.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
Continúa leyendo abajo
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Próxima revisión: 6 de agosto de 2026
7 Ago 2023 | Última versión

Pregunta, comparte, conecta.
Navega por discusiones, haz preguntas y comparte experiencias en cientos de temas de salud.
Suscríbete al boletín de Patient
Tu dosis semanal de consejos de salud claros y confiables, escritos para ayudarte a sentirte informado, seguro y en control.
By subscribing you accept our Política de Privacidad. Puedes darte de baja en cualquier momento. Nunca vendemos tus datos.