Etosuximida para la epilepsia
Emeside, Epesri
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 10 Ene 2024
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Take ethosuximide regularly. Most people are prescribed two doses a day.
Do not stop taking it unless your doctor tells you to.
Ethosuximide may make you feel sick (nausea) when you first start taking it. This should soon settle down.
De un vistazo
Ethosuximide is a medicine used to treat absence seizures in epilepsy, mainly in children and young people.
It helps reduce seizures by stabilising abnormal electrical activity in the brain.
Take ethosuximide exactly as your doctor tells you, usually twice a day.
A common side-effect is feeling sick, abdominal discomfort, or headaches.
If you experience mood changes or distressing thoughts, tell your doctor straightaway.
Do not stop taking ethosuximide suddenly, as this can cause problems.
If you have a high temperature, mouth ulcers, or unexplained bruising, contact your doctor immediately.
About ethosuximide
Tipo de medicamento | Un medicamento antiepiléptico |
Usado para | Epilepsy with absence seizures |
También llamado | Emeside®, Epesri® |
Disponible como | Capsules and oral liquid medicine |
Absence seizures are a form of epilepsy. They mainly occur in children and young people. Absence seizures are a brief loss of consciousness (an 'absence') for a few seconds, and can appear like daydreaming. Although no underlying cause for this type of seizure can be found, it is thought that the brain develops a low threshold for bursts of abnormal electrical activity. Ethosuximide is one of the medicines commonly prescribed for this type of epilepsy. It helps to reduce absence seizures by stabilising the abnormal electrical activity in the brain.
Ethosuximide is occasionally prescribed for some other types of seizures.
Before taking ethosuximide
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you (or your child if you are the carer) start taking ethosuximide it is important that your doctor knows:
Si estás embarazada, intentando tener un bebé o amamantando.
Si tienes algún problema con el funcionamiento de tus riñones o con el funcionamiento de tu hígado.
Si tienes un trastorno sanguíneo hereditario raro llamado porfiria.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
Si alguna vez has tenido una reacción alérgica a un medicamento.
How to take ethosuximide
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about ethosuximide and will provide you with a full list of the side-effects which you may experience from taking it.
Take ethosuximide exactly as your doctor tells you to. Your dose will be printed on the label of the pack of medicine to remind you about what the doctor said. It is usual to start treatment on a low dose, and then for the dose to be increased gradually to a regular maintenance dose. It is usual to take two doses each day. Doses for children are tailored to their age and weight.
Try to take your doses at the same times of day, each day. Having a routine will help you to remember to take your doses regularly. You can take ethosuximide either before or after meals. If you are taking capsules, swallow them with a drink of water.
If you (or your child) have been given ethosuximide oral liquid medicine, remember to shake the bottle well before you measure out the dose. It is also a good idea to brush your (or your child's) teeth after each dose as the medicine contains sugar.
Si olvida tomar una dosis, tómela tan pronto como lo recuerde, a menos que esté cerca la hora de su próxima dosis, en cuyo caso omita la dosis olvidada. No tome dos dosis juntas para compensar una dosis olvidada.
Obteniendo el máximo de tu tratamiento
Cuando comienzas un nuevo tratamiento para la epilepsia, puede haber un cambio en el número o tipo de convulsiones que experimentas. Tu médico te aconsejará al respecto.
Intenta mantener tus citas regulares con tu médico. Esto es para que tu médico pueda verificar tu progreso.
Different formulations and makes of ethosuximide can act in a slightly different way in your body. Because of this, your doctor may recommend that you continue to take ethosuximide from the same manufacturer each time you obtain a new supply. If so, each time you collect a prescription, check to make sure your supply looks the same and that the name is the same. If you are unsure, or if you have any questions about your prescription, please ask your pharmacist to advise you.
If you buy any medicines, check with a pharmacist that they are suitable for you to take.
Mientras estás siendo tratado por epilepsia, existe un pequeño riesgo de que puedas desarrollar cambios de humor, pensamientos angustiantes y sentimientos sobre el suicidio. Si esto ocurre, debes informar a tu médico de inmediato.
Las personas con epilepsia deben dejar de conducir al principio. Su médico le aconsejará cuándo podría ser posible que vuelva a conducir. Esto generalmente será después de un año sin convulsiones.
Antiepileptic medicines can harm an unborn child. If you are a woman, make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. If you want to have a family, discuss this with your doctor so that you can be given advice from a specialist antes te quedas embarazada.
You need to take ethosuximide regularly every day. Do not stop taking it unless your doctor tells you to stop. Stopping treatment suddenly can cause problems and your doctor will want you to reduce your dose gradually if this becomes necessary.
If you drink alcohol, ask your doctor for advice. Your doctor may advise you not to drink alcohol while you are on this medicine.
Can ethosuximide cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with ethosuximide. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common ethosuximide side-effects (these affect less than 1 in 10 people) | ¿Qué puedo hacer si experimento esto? |
Sentirse mal (náuseas) o estar enfermo (vómitos), malestar en el vientre (abdominal) | Try to stick to simple meals - avoid rich or spicy foods |
Dolor de cabeza | Bebe mucha agua y pide a tu farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza continúan, informa a tu médico |
Sintiéndose mareado, cansado o somnoliento | Si esto sucede, no conduzcas y no uses herramientas ni máquinas |
Diarrea | Bebe mucha agua para reponer los líquidos perdidos |
Lack of appetite, feeling unsteady, itchy skin rash, mood changes | Si alguno de estos se vuelve problemático, hable con su médico para obtener consejo |
Importante: your doctor will discuss with you the possibility that ethosuximide can cause blood disorders. Although these occur less commonly than the side-effects listed above, it is important that you contact your doctor de inmediato if you experience any of the following symptoms:
Una temperatura alta (fiebre).
Úlceras bucales.
Moretones o sangrado inexplicables.
If you experience any other symptoms which you think may be due to ethosuximide, speak with your doctor or pharmacist for further advice.
How to store ethosuximide
Mantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
Si vas a someterte a una operación o tratamiento dental, informa a la persona que realiza el tratamiento sobre los medicamentos que estás tomando.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
MHRA - Reporte de reacciones adversas
Informe los efectos secundarios sospechosos de medicamentos, vacunas, cigarrillos electrónicos, incidentes con dispositivos médicos, productos defectuosos o falsificados (falsos) a la Agencia Reguladora de Medicamentos y Productos Sanitarios para garantizar un uso seguro y efectivo.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Preguntas frecuentes
Can I take other medicines, including over-the-counter remedies or herbal supplements, while on ethosuximide?
It's important to inform your doctor about any other medicines you are taking, including those available without a prescription, as well as herbal and complementary medicines. This is because some medicines may not be suitable to take with ethosuximide, or may require extra care.
How soon should I expect to see a difference in my seizures after starting ethosuximide?
When you first start a new epilepsy treatment like ethosuximide, there might be a change in the number or type of seizures you experience. Your doctor will provide specific advice regarding expectations for your individual situation.
Are there any specific concerns about ethosuximide if I have kidney or liver problems?
Yes, if you have any problems with how your kidneys or liver work, it's important to tell your doctor before starting ethosuximide. They will need to know this information to ensure the medicine is appropriate for you and to take any necessary precautions.
What should I do if I notice an itchy skin rash after taking ethosuximide?
An itchy skin rash can be a side-effect of ethosuximide. If this becomes troublesome, you should speak with your doctor for advice.
If I switch to a different brand or formulation of ethosuximide, will it affect my treatment?
Different formulations and brands of ethosuximide can act slightly differently in your body. Your doctor might recommend that you consistently use ethosuximide from the same manufacturer. If this is the case, always check your new supply to ensure it looks and is named the same. If you have any concerns, ask your pharmacist.
What are the signs of blood disorders that I should watch out for while taking ethosuximide?
While less common than other side-effects, ethosuximide can cause blood disorders. You should contact your doctor immediately if you experience a high temperature (fever), mouth ulcers, or unexplained bruising or bleeding.
Lecturas adicionales y referencias
- Manufacturer's PIL, Ethosuximide 250 mg/5 ml Syrup; Essential Pharma Ltd, The electronic Medicines Compendium. Dated May 2023.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
Sobre el autorVer biografía completa

Michael Stewart, MRPharmS
Gerente de Revisión de Folletos de Medicamentos – Contratista, Farmacéutico
BPharm (Hons), MRPharmS
Michael es un farmacéutico comunitario que ejerce en Midlands y South Yorkshire con más de 20 años de experiencia asesorando sobre medicamentos y condiciones médicas. Tiene una sólida formación en capacitación en atención médica, habiendo producido e impartido cursos de formación para equipos de farmacia y personal de entornos de atención residencial, incluidas enfermeras. También ha contribuido a juntas asesoras de farmacia para la gestión de condiciones de baja gravedad en la comunidad.
Acerca del revisor

Sid Dajani
Sultan Dajani se graduó en la Escuela de Farmacia de Londres en 1994 y se convirtió en el miembro más joven elegido para el consejo de la Sociedad Real de Farmacia desde su fundación en 1842.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Artículo también disponible en Inglés, Alemán, Español, Francés, Italiano, Portugués, Hindi, Hebreo, Árabe, y Sueco.
Próxima revisión: 9 de enero de 2027
10 Ene 2024 | Última versión

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