Proclorperazina
Buccastem, Stemetil
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSLast updated 29 Mar 2023
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Prochlorperazine is prescribed for a number of different reasons. Ask your doctor if you are unsure why it has been prescribed for you.
It may slow your reactions and make you feel drowsy. If this happens, do not drive and do not use tools or machines.
Keep any regular appointments with your doctor. This is so your progress can be checked.
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About prochlorperazine
Tipo de medicamento | A phenothiazine medicine |
Usado para | The treatment of dizziness and problems with balance; the treatment of nausea and vomiting; to ease agitation and severe restlessness; schizophrenia |
También llamado | Buccastem® M; Stemetil® |
Disponible como | Tablet, buccal tablet (dissolves in the mouth)and injection |
Prochlorperazine belongs to a group of medicines called 'phenothiazines'. It is prescribed for a variety of unrelated conditions, including problems with balance and dizziness, sickness (nausea and vomiting), agitation and restlessness, and esquizofrenia. Prochlorperazine is thought to work by blocking the action of a chemical called dopamine which acts on the nervous system in the brain.
Prochlorperazine is also available to buy over-the-counter from pharmacies. It comes as a buccal tablet (dissolves in the mouth) that is used to relieve sickness caused by migraña.
Before taking prochlorperazine
Volver al contenidoSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking prochlorperazine it is important that your doctor knows:
Si estás embarazada o amamantando.
Si tienes una afección cardíaca o enfermedad de los vasos sanguíneos.
Si tienes problemas de hígado, riñón o próstata.
Si tienes problemas para respirar.
If you have problems with your thyroid gland.
If you have any of the following: epilepsy, Parkinson's disease, depression, increased pressure in your eye (glaucoma), or myasthenia gravis, a condition which causes muscle weakness.
Si alguna vez ha tenido amarillamiento de la piel o de la parte blanca de los ojos (ictericia) o un trastorno de la sangre.
Si tienes un tumor en la glándula suprarrenal, una condición llamada feocromocitoma.
Si alguna vez has tenido una reacción alérgica a un medicamento.
Si está tomando o usando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
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How to take prochlorperazine
Volver al contenidoBefore you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The manufacturer's leaflet will give you more information about prochlorperazine and a full list of the side-effects which you may experience from taking it.
Take prochlorperazine exactly as your doctor tells you to. Your dose will depend upon the reason you are taking it, but as a guide, it is often taken two or three times daily. If you are prescribed a regular dose, try to get into the habit of taking it at the same times each day to avoid missing any doses. Prochlorperazine can also be taken 'as required' when treating sickness.
If you have been supplied the standard 5 mg tablets - take these in the normal way by swallowing them with a glass of water. You can take prochlorperazine 5 mg tablets before or after meals.
If you have been supplied the 3 mg buccal tablets (Buccastem® M brand) - the tablets are designed to stick to the inside of your mouth and to dissolve there. Place the tablet in your mouth, high up between your top gum and upper lip. Leave it in place - the tablet will dissolve slowly over the following hour or so. It is best to take prochlorperazine buccal tablets after meals.
Si olvida tomar una dosis, tómela tan pronto como lo recuerde, a menos que esté cerca de la hora de su próxima dosis, en cuyo caso omita la dosis olvidada. No tome dos dosis juntas para compensar una dosis olvidada.
Obteniendo el máximo de tu tratamiento
Volver al contenidoKeep your regular doctor's appointments so your progress can be checked. If you are taking prochlorperazine for a long-term condition, you may need to have some blood tests from time to time.
If you have been given prochlorperazine to relieve nausea, dizziness or agitation, it will be given to you for a short time until your symptoms have eased. If you have been prescribed prochlorperazine for schizophrenia, treatment is usually long-term. Keep taking prochlorperazine until your doctor tells you otherwise, as your doctor may want you to reduce your dose gradually if a change in your treatment becomes necessary.
Prochlorperazine may cause your skin to become more sensitive to sunlight than normal. Use a sunscreen that protects against UVA light and has a sun protection factor (SPF) of at least 15, especially in strong sunlight or until you know how your skin reacts. Do not use sunbeds.
If you are having an operation or any dental treatment, tell the person carrying out the treatment which medicines you are taking. This is important because prochlorperazine may interfere with any anaesthetic you receive.
If you buy or take any 'over-the-counter' medicines, check with a pharmacist that they are suitable to take with prochlorperazine. Antacid remedies should not be taken at the same time, as they reduce the amount of prochlorperazine absorbed by your body.
If you drink alcohol, ask your doctor for advice about drinking while you are on prochlorperazine. Alcohol will increase the chance that you experience side-effects and is unlikely to be recommended for you.
If you have diabetes, check your blood sugar (glucose) levels regularly, as prochlorperazine may affect the levels of sugar in your blood.
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Can prochlorperazine cause problems?
Volver al contenidoAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with prochlorperazine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Común prochlorperazine side-effects | ¿Qué puedo hacer si experimento esto? |
Sentirse mareado o somnoliento, visión borrosa, tiempo de reacción reducido | Si esto ocurre, no conduzca y no utilice herramientas o máquinas. No consuma alcohol |
Dolor de cabeza | Bebe mucha agua y pide a un farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza continúan, informa a tu médico |
Boca seca | Intenta masticar chicle sin azúcar o chupar caramelos sin azúcar |
Sensación de temblores o inquietud, movimientos musculares inusuales o incontrolables | Hable con su médico lo antes posible sobre cualquiera de estos. Es posible que su tratamiento necesite ajustes |
Changes to the way your body regulates temperature | Take care in hot or cold weather to make sure that you do not get too hot or too cold |
Changes in weight, difficulty sleeping, mood changes, stuffy nose, changes in sexual function, breast enlargement, production of breast milk, menstrual problems, fast heartbeats, constipation, difficulty passing urine | Consulte a su médico si alguno de estos le causa molestias |
Importante: if you experience symptoms such as muscle stiffness, a very high temperature, confusion, a fast heartbeat and sweating, you must contact your doctor immediately. These may be signs of a rare but serious condition known as neuroleptic malignant syndrome.
Si experimenta otros síntomas que cree que pueden deberse a este medicamento, hable con su médico o farmacéutico.
How to store prochlorperazine
Volver al contenidoMantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Volver al contenidoInformación importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Yellow Card website.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Lecturas adicionales y referencias
- Manufacturer's PIL, Buccastem® M; Alliance Pharmaceuticals, The electronic Medicines Compendium. Dated February 2020.
- Manufacturer's PIL, Stemetil® Tablets 5 mg; Sanofi, El Compendio Electrónico de Medicamentos. Fecha enero de 2022.
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Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Next review due: 27 Sept 2027
29 Mar 2023 | Última versión

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