Trazodona
Molipaxin
Revisado por pares por Dr Colin Tidy, MRCGPÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 7 Nov 2022
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Mantén tus citas regulares con tu médico. Esto es para que tu médico pueda verificar tu progreso.
Take your doses after a meal or a snack. Try not to drink any alcohol whilst being treated with trazodone as it will increase the chance of you feeling drowsy.
Common side effects of trazodone include drowsiness, dizziness, dry mouth, headache, and nausea.
This medicine may make you sleepy. If this happens, do not drive and do not use tools or machines.
Tell your doctor if you experience any troublesome side effects.
De un vistazo
Trazodone is a medicine used to treat depression and anxiety in adults.
It helps ease symptoms like low mood, poor sleep, and poor concentration.
Common side effects include dizziness, sleepiness, blurred vision, dry mouth, and constipation.
Do not drive or use machines if you feel sleepy or have blurred vision.
Speak to your doctor if you are pregnant, breastfeeding, or have certain other medical conditions.
Take this medicine exactly as your doctor has told you, usually after meals.
It can take 4-6 weeks to feel the full benefit of trazodone.
About trazodone
Tipo de medicamento | Tricyclic-related antidepressant |
Usado para | Depression and/or anxiety in adults |
También llamado | Molipaxin® |
Disponible como | Capsules, tablets, and liquid medicine |
What is trazodone used for?
Trazodone is used to treat depresión y ansiedad. It is a type of medicine called a tricyclic-related antidepressant.
Antidepresivos like trazodone are used to ease symptoms such as low mood, poor sleep and poor concentration. This in turn allows you to function more normally and cope better with any difficult circumstances. Trazodone also helps to reduce the symptoms of anxiety, even if you are not depressed.
Depression and anxiety can develop for no apparent reason, or they may be triggered by a life event such as a relationship problem, bereavement, or illness.
Side effects of trazodone
The most common side effects of trazodone are:
Feeling dizzy or faint.
Feeling sleepy or tired.
Visión borrosa.
Boca seca.
Estreñimiento.
Dolor de cabeza.
You may also experience other side effects such as:
Feeling irritable or confused.
Tingling sensation or a numb feeling.
Sensibilidad en los senos.
Not being able to ejaculate.
Increased or decreased sex drive (libido).
Increased appetite and weight gain.
Dificultad para orinar.
Indigestión.
Latido cardíaco acelerado.
General aches and pains.
Encontrará una lista completa en el prospecto del fabricante que se suministra con su medicamento. Los efectos no deseados a menudo mejoran a medida que su cuerpo se adapta al nuevo medicamento, pero hable con su médico o farmacéutico si alguno de los siguientes persiste o se vuelve problemático.
How to manage trazodone side effects
Common trazodone side effects | ¿Qué puedo hacer si experimento esto? |
Feeling dizzy or faint | Levantarse más despacio puede ayudar. Si comienza a sentirse mareado, siéntese hasta que pase la sensación |
Sensación de sueño o cansancio, visión borrosa | Si esto ocurre, no conduzca y no utilice herramientas o máquinas. No consuma alcohol |
Boca seca | Intenta masticar chicle sin azúcar o chupar caramelos sin azúcar |
Estreñimiento | Try to eat a well-balanced diet containing plenty of fibre, and drink plenty of water |
Feeling irritable or confused, tingling or numb feelings, breast tenderness, difficulties with sexual function, increased appetite and weight gain, difficulty passing urine, indigestion, a fast heartbeat, aches and pains | Hable con su médico si alguno de estos se vuelve problemático |
Si experimenta otros síntomas que cree que pueden deberse a este medicamento, hable con su médico o farmacéutico.
Who should not take trazodone?
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking trazodone it is important that your doctor or pharmacist knows:
Si estás embarazada, intentando concebir o amamantando.
If you have thyroid problems.
If you have liver, kidney or heart problems.
If you have epilepsy or diabetes (diabetes mellitus).
If you are troubled by constipation which lasts several days.
If you have any difficulties passing urine, or have had prostate trouble.
If you have ever had a mental health problem (such as bipolar disorder or psychosis).
If you have increased pressure in the eye (glaucoma).
If you have been told you have a tumour on your adrenal gland, called phaeochromocytoma.
Si tienes un trastorno sanguíneo hereditario raro llamado porfiria.
If you are taking other medicines, including those available to buy without a prescription, as well as herbal and complementary medicines. This is especially important if you have recently taken a medicine for depression, known as a monoamine-oxidase inhibitor (MAOI).
Si alguna vez has tenido una reacción alérgica a un medicamento.
How to take trazodone
Read the manufacturer's printed information leaflet from inside your pack. This will give you more information about trazodone and a full list of side effects which you may experience from taking it.
You may be prescribed trazodone to take once a day, at bedtime. Some doctors, however, may recommend smaller doses taken two or three times a day. Your doctor will tell you which is right for you and your dose will also be on the label of the pack to remind you.
Take trazodone exactly as your doctor has told you to. It can cause drowsiness so your doctor may advise you to take a smaller dose to begin with, and then to increase it as your body gets used to the medicine.
Take trazodone after meals. If you are taking your doses at bedtime, have a light snack beforehand.
If you forget to take a dose take it as soon as you remember, unless it is nearly time for your next dose in which case leave out the forgotten dose. Do not take two doses together to make up for a missed dose.
Obteniendo el máximo de tu tratamiento
Intenta mantener tus citas regulares con tu médico. Esto es para que tu médico pueda verificar tu progreso.
You may feel that trazodone is not working for you straightaway. It can take a week or two after starting it before the effect begins to build up, and 4-6 weeks before you feel the full benefit. It is important that you do not stop taking it after a week or so, thinking it is not helping.
If you feel depressed, you may have distressing thoughts and think about harming yourself or ending your life. If this happens, it is very important that you tell your doctor about this as soon as possible.
If you drink alcohol, ask your doctor for advice. Your doctor is likely to recommend that you do not drink alcohol while you are on trazodone, as it increases the risk of side effects, such as feeling sleepy.
If you are taking trazodone for depression, your doctor may ask you to carry on taking it even after you feel better. This is to help stop the depression from returning.
It is normal for a course of treatment to last for around six months after your symptoms have eased.
Continue to take trazodone unless your doctor tells you otherwise. Stopping treatment suddenly can sometimes cause problems and your doctor may want you to reduce your dose gradually if this is necessary.
If you buy any medicines, check with a pharmacist that they are suitable for you to take. This is because a number of medicines which can be bought from pharmacies and other retail outlets can increase the risk of side effects from trazodone. These include antihistamine medicines, and St John's wort.
If you have diabetes you may need to check your blood sugar (glucose) more frequently. This is because trazodone may affect the levels of sugar in your blood. Your doctor will advise you about this.
If you are having any medical or dental treatment, tell the person carrying out the treatment that you are taking this medicine.
How to store trazodone
Mantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda de inmediato al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Sitio web de Yellow Card.
Preguntas frecuentes
Is trazodone a SSRI or SNRI?
Trazodone is neither an SSRI nor an SNRI, it is a SARI (serotonin antagonist and reuptake inhibitor).
How long after I take trazodone will I fall asleep?
Trazodone usually helps with sleep within 30-60 minutes, however it may take a few nights for it to consistently work.
Is trazodone a controlled drug?
Trazodone is not a controlled drug, but it is prescription-only and should be taken under medical supervision.
Will trazodone affect my sex drive?
Trazodone can cause some people to have a lower sex drive, difficulty with arousal, or delayed orgasm, while others experience little or no change.
Does trazodone make you gain weight?
Trazodone may cause weight gain due to an increased appetite, but most people don’t gain a significant amount. Speak to your doctor if any weight gain is concerning or bothering you.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Preguntas frecuentes
Can trazodone affect blood sugar levels?
Yes, trazodone may affect the levels of sugar in your blood. If you have diabetes, your doctor may advise you to check your blood sugar (glucose) more frequently while taking this medication.
What is Molipaxin?
Molipaxin is a brand name for the medicine trazodone. It is a type of antidepressant used to treat depression and anxiety.
When should I take trazodone for depression?
Your doctor will advise you on the best time to take trazodone. Some doctors may suggest taking it once a day at bedtime, while others might recommend smaller doses two or three times a day. It is important to take it exactly as prescribed, after meals or with a light snack if taking it at bedtime.
Does trazodone cause dry mouth?
Yes, dry mouth is a common side effect of trazodone. To manage this, you can try chewing sugar-free gum or sucking sugar-free sweets.
How long does it take for trazodone to start working?
You may not feel the effects of trazodone straight away. It can take one to two weeks before you notice the effect building up, and four to six weeks to feel the full benefit. It's important not to stop taking it prematurely if you don't feel immediate improvement.
Lecturas adicionales y referencias
- Manufacturer's PIL, Trazodone Hydrochloride 50 mg and 100 mg Capsules; Zentiva, The electronic Medicines Compendium. Dated February 2022.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
Sobre el autorVer biografía completa

Michael Stewart, MRPharmS
Gerente de Revisión de Folletos de Medicamentos – Contratista, Farmacéutico
BPharm (Hons), MRPharmS
Michael es un farmacéutico comunitario que ejerce en Midlands y South Yorkshire con más de 20 años de experiencia asesorando sobre medicamentos y condiciones médicas. Tiene una sólida formación en capacitación en atención médica, habiendo producido e impartido cursos de formación para equipos de farmacia y personal de entornos de atención residencial, incluidas enfermeras. También ha contribuido a juntas asesoras de farmacia para la gestión de condiciones de baja gravedad en la comunidad.
Acerca del revisorVer biografía completa

Dr Colin Tidy, MRCGP
Médico General, Autor Médico
MBBS, MRCGP, MRCP (Paediatrics), DCH
El Dr. Colin Tidy es un médico del NHS, con sede en Oxfordshire.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Artículo también disponible en Inglés, Alemán, Español, Francés, Italiano, Portugués, Hindi, Hebreo, Árabe, y Sueco.
Next review due: 6 May 2027
7 Nov 2022 | Última versión

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