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Olanzapine

Zalasta, Zyprexa

Olanzapine belongs to a group of medicines called antipsychotics. It is taken once daily.

Acuda regularmente a las citas con su médico. Así podrá comprobar su evolución.

The most common side-effects include feeling sleepy or dizzy, and increased weight.

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About olanzapine

Tipo de medicamento

Un medicamento antipsicótico

Utilizado para

Easing the symptoms of schizophrenia and mania; preventing high mood swings in bipolar disorder

También llamado

Zalasta®; Zyprexa®

Disponible como

Tablets, and melt-in-the-mouth (orodispersible) tablets

Olanzapine belongs to a group of medicines called antipsychotics. It may have been prescribed for you to relieve the symptoms of schizophrenia, or alternatively, it may have been prescribed for the treatment and/or prevention of high mood swings (mania). In both of these conditions, olanzapine works on the balance of chemical substances in your brain.

Maintenance doses of olanzapine can also be given to people with schizophrenia by depot injection. There is a separate medicine leaflet providing more information about this, called Olanzapine long-acting injection.

Before taking olanzapine

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking olanzapine it is important that your doctor knows:

  • Si está embarazada o en periodo de lactancia.

  • Si padece una cardiopatía o una enfermedad vascular.

  • Si tiene problemas de hígado, riñón o próstata.

  • Si tiene problemas para respirar.

  • If you are very constipated or think you may have a blockage in your bowel.

  • If you have any of the following: epilepsy, diabetes (diabetes mellitus), depression, Parkinson's disease, raised pressure in your eye (glaucoma) or a condition which causes muscle weakness, called myasthenia gravis.

  • If you have ever had yellowing of your skin or of the whites of your eyes (jaundice).

  • If you have a blood or bone marrow disorder.

  • Si tiene un tumor en la glándula suprarrenal (una enfermedad llamada feocromocitoma).

  • Si ha tenido una reacción alérgica a un medicamento.

  • Si toma o utiliza otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que pueda adquirirse sin receta, así como medicamentos a base de plantas y complementarios.

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How to take olanzapine

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about olanzapine and it will also provide you with a full list of the side-effects which you may experience from taking it.

  • Your dose will be adjusted to suit your condition, so take olanzapine tablets exactly as your doctor tells you to. It is usual to be prescribed one dose of olanzapine to take each day. Your dose will be printed on the label of your pack to remind you about what the doctor said to you.

  • You can take olanzapine tablets either before or after meals.

  • Try to get into the habit of taking your dose at the same time of day each day, as this will help you to remember to take it. If you do forget to take a dose, take it as soon as you remember. If you do not remember until the following day then skip the missed dose but remember to take the dose that is due on that day. Do not take two doses at the same time to make up for a forgotten dose.

  • If you have been given orodispersible tablets (e.g Zyprexa® Velotabs) - these are tablets which dissolve in your mouth - place the tablet on your tongue and allow it to dissolve. Alternatively, if you prefer, you can take the orodispersible tablet stirred into a small glassful of any of the following drinks: water, orange or apple juice, milk or coffee.

Aproveche al máximo su tratamiento

  • Your treatment will require careful monitoring to make sure that you get the best possible benefit from olanzapine. Keep your regular doctor's appointments so that your progress can be checked. You will need to have some tests from time to time.

  • Treatment with olanzapine is usually long-term unless you experience an adverse effect. Keep taking it unless your doctor tells you otherwise. Stopping olanzapine suddenly can cause problems, so your doctor may want you to reduce your dose gradually if this becomes necessary.

  • If you drink alcohol, ask your doctor for advice. Alcohol increases the risk of side-effects from olanzapine so it is best avoided.

  • If you have diabetes you may need to check your blood glucose more frequently, as olanzapine may affect the levels of sugar in your blood. Your doctor will advise you about this.

  • Some medicines similar to olanzapine can cause the skin to become more sensitive to sunlight than normal. It may be advisable to use a sunscreen in bright sunlight until you know how your skin reacts.

  • Smoking may affect the amount of olanzapine in your body. Let your doctor know if you either start or stop smoking while you are taking olanzapine.

  • Un pequeño número de personas que toman medicamentos para los trastornos del estado de ánimo pueden tener pensamientos de hacerse daño o acabar con su vida, sobre todo cuando empiezan a tomar un nuevo medicamento. Si esto le ocurre, es muy importante que se lo comunique a su médico.

  • If you are due to have any medical or dental treatment, tell the person carrying out the treatment which medicines you are taking. This is important because olanzapine may interfere with any anaesthetic you receive.

  • If you buy or take any 'over-the-counter' medicines or herbal remedies, please check with a pharmacist that they are suitable for you to take with olanzapine.

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Can olanzapine cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with olanzapine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common olanzapine side-effects (these affect more than 1 in 10 people)

¿Qué puedo hacer si me ocurre esto?

Sensación de sueño o mareo

No conduzca ni utilice herramientas o máquinas

Increased weight

Eat a well-balanced diet. Speak with a pharmacist if your weight becomes troublesome

Cambios en los resultados de algunos análisis de sangre

Su médico vigilará

Common olanzapine side-effects (these affect fewer than 1 in 10 people)

¿Qué puedo hacer si me ocurre esto?

Feeling restless or tired

Speak with your doctor about this. Do not drive and do not use tools or machines while affected

Estreñimiento

Drink plenty of water and eat a well-balanced diet

Boca seca

Prueba a mascar chicle sin azúcar o chupar caramelos sin azúcar

Unusual or uncontrollable muscle movements

Speak with your doctor about these

Increased appetite, feeling hot, swollen hands or feet, skin rash, reduced interest in sex, erectile dysfunction, aches and pains

Coméntelo con su médico si alguno le resulta molesto

Importante: si experimenta síntomas como rigidez muscular, temperatura muy alta (fiebre), sensación de confusión, taquicardia y sudoración, debe ponerse en contacto con su médico inmediatamente. Pueden ser signos de una enfermedad rara pero grave conocida como síndrome neuroléptico maligno.

Si experimenta cualquier otro síntoma que crea que puede deberse a los comprimidos, consulte a su médico o farmacéutico.

How to store olanzapine

  • Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.

  • Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.

Información importante sobre todos los medicamentos

Información importante sobre todos los medicamentos

No tome nunca más de la dosis prescrita. Si sospecha que usted u otra persona ha tomado una sobredosis de este medicamento, acuda al servicio de urgencias de su hospital. Llévese el envase, aunque esté vacío.

Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.

No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.

Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.

Informar de los efectos secundarios de un medicamento o vacuna

Si experimenta efectos secundarios, puede notificarlos en línea a través del sitio web de la Tarjeta Amarilla.

Lecturas complementarias y referencias

Historia del artículo

La información de esta página ha sido redactada y revisada por médicos cualificados.

  • Fecha de la próxima revisión: 1 de agosto de 2027
  • 5 ago 2024 | Última versión

    Última actualización

    Michael Stewart, MRPharmS

    Revisado por expertos

    Sid Dajani
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