Olanzapine
Zalasta, Zyprexa
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 5 Ago 2024
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Olanzapine belongs to a group of medicines called antipsychotics. It is taken once daily.
Mantén tus citas regulares con tu médico. Esto es para que se pueda verificar tu progreso.
The most common side-effects include feeling sleepy or dizzy, and increased weight.
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About olanzapina
Tipo de medicamento | Un medicamento antipsicótico |
Usado para | Easing the symptoms of schizophrenia and mania; preventing high mood swings in bipolar disorder |
También llamado | Zalasta®; Zyprexa® |
Disponible como | Tablets, and melt-in-the-mouth (orodispersible) tablets |
Olanzapine belongs to a group of medicines called antipsychotics. It may have been prescribed for you to relieve the symptoms of esquizofrenia, or alternatively, it may have been prescribed for the treatment and/or prevention of high mood swings (mania). In both of these conditions, olanzapine works on the balance of chemical substances in your brain.
Maintenance doses of olanzapine can also be given to people with schizophrenia by depot injection. There is a separate medicine leaflet providing more information about this, called Olanzapine long-acting injection.
Before taking olanzapine
Volver al contenidoSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking olanzapine it is important that your doctor knows:
Si estás embarazada o amamantando.
Si tienes una afección cardíaca o enfermedad de los vasos sanguíneos.
Si tienes problemas de hígado, riñón o próstata.
Si tienes algún problema con tu respiración.
If you are very constipated or think you may have a blockage in your bowel.
If you have any of the following: epilepsy, diabetes (diabetes mellitus), depression, Parkinson's disease, raised pressure in your eye (glaucoma) or a condition which causes muscle weakness, called myasthenia gravis.
If you have ever had yellowing of your skin or of the whites of your eyes (jaundice).
If you have a blood or bone marrow disorder.
Si tienes un tumor en la glándula suprarrenal (una condición llamada feocromocitoma).
Si ha tenido una reacción alérgica a un medicamento.
Si está tomando o usando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
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How to take olanzapine
Volver al contenidoBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about olanzapine and it will also provide you with a full list of the side-effects which you may experience from taking it.
Your dose will be adjusted to suit your condition, so take olanzapine tablets exactly as your doctor tells you to. It is usual to be prescribed one dose of olanzapine to take each day. Your dose will be printed on the label of your pack to remind you about what the doctor said to you.
You can take olanzapine tablets either before or after meals.
Try to get into the habit of taking your dose at the same time of day each day, as this will help you to remember to take it. If you do forget to take a dose, take it as soon as you remember. If you do not remember until the following day then skip the missed dose but remember to take the dose that is due on that day. Do not take two doses at the same time to make up for a forgotten dose.
If you have been given orodispersible tablets (e.g Zyprexa® Velotabs) - these are tablets which dissolve in your mouth - place the tablet on your tongue and allow it to dissolve. Alternatively, if you prefer, you can take the orodispersible tablet stirred into a small glassful of any of the following drinks: water, orange or apple juice, milk or coffee.
Obteniendo el máximo de tu tratamiento
Volver al contenidoYour treatment will require careful monitoring to make sure that you get the best possible benefit from olanzapine. Keep your regular doctor's appointments so that your progress can be checked. You will need to have some tests from time to time.
Treatment with olanzapine is usually long-term unless you experience an adverse effect. Keep taking it unless your doctor tells you otherwise. Stopping olanzapine suddenly can cause problems, so your doctor may want you to reduce your dose gradually if this becomes necessary.
If you drink alcohol, ask your doctor for advice. Alcohol increases the risk of side-effects from olanzapine so it is best avoided.
If you have diabetes you may need to check your blood glucose more frequently, as olanzapine may affect the levels of sugar in your blood. Your doctor will advise you about this.
Some medicines similar to olanzapine can cause the skin to become more sensitive to sunlight than normal. It may be advisable to use a sunscreen in bright sunlight until you know how your skin reacts.
Smoking may affect the amount of olanzapine in your body. Let your doctor know if you either start or stop smoking while you are taking olanzapine.
Un pequeño número de personas que toman medicamentos para trastornos del estado de ánimo pueden tener pensamientos de hacerse daño a sí mismos o de acabar con sus vidas, especialmente cuando se comienza un nuevo medicamento. Es muy importante que le informe a su médico sobre esto si le sucede a usted.
If you are due to have any medical or dental treatment, tell the person carrying out the treatment which medicines you are taking. This is important because olanzapine may interfere with any anaesthetic you receive.
If you buy or take any 'over-the-counter' medicines or herbal remedies, please check with a pharmacist that they are suitable for you to take with olanzapine.
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Can olanzapine cause problems?
Volver al contenidoAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with olanzapine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common olanzapine side-effects (these affect more than 1 in 10 people) | ¿Qué puedo hacer si experimento esto? |
Feeling sleepy or dizzy | No conduzca y no utilice herramientas o máquinas |
Increased weight | Eat a well-balanced diet. Speak with a pharmacist if your weight becomes troublesome |
Cambios en algunos resultados de análisis de sangre | Su médico supervisará estos |
Common olanzapine side-effects (these affect fewer than 1 in 10 people) | ¿Qué puedo hacer si experimento esto? |
Feeling restless or tired | Speak with your doctor about this. Do not drive and do not use tools or machines while affected |
Estreñimiento | Drink plenty of water and eat a well-balanced diet |
Boca seca | Intenta masticar chicle sin azúcar o chupar caramelos sin azúcar |
Movimientos musculares inusuales o incontrolables | Speak with your doctor about these |
Increased appetite, feeling hot, swollen hands or feet, skin rash, reduced interest in sex, erectile dysfunction, aches and pains | Discuss these with your doctor if any become troublesome |
Importante: si experimenta síntomas como rigidez muscular, una temperatura muy alta (fiebre), confusión, un ritmo cardíaco rápido y sudoración, debe contactar a su médico de inmediato. Estos pueden ser signos de una condición rara pero grave conocida como síndrome neuroléptico maligno.
Si experimenta cualquier otro síntoma que crea que puede deberse a las tabletas, por favor hable con su médico o farmacéutico para obtener más consejos.
How to store olanzapine
Volver al contenidoMantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Volver al contenidoInformación importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de sitio web de la Tarjeta Amarilla.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Lecturas adicionales y referencias
- Manufacturer's PIL, Zyprexa 2.5 mg, 5 mg, 7.5 mg, 10 mg, 15 mg, 20 mg film-coated tablets; Neon Healthcare Ltd, The electronic Medicines Compendium. Dated December 2023.
- Manufacturer's PIL, Zyprexa Velotab® 5 mg, 10 mg, 15 mg and 20 mg orodispersible Tablets; Neon Healthcare Ltd, The electronic Medicines Compendium. Dated December 2023.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
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Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Próxima revisión: 1 de agosto de 2027
5 Ago 2024 | Última versión

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