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Quinina para calambres en las piernas

The usual dose of quinine for leg cramps is one tablet at bedtime. The strength of the tablet will be either 200 mg or 300 mg.

Quinine is present in drinks such as tonic water and bitter lemon - try to avoid these while you are on quinine.

Contact a doctor inmediatamente if anyone swallows quinine by accident, or if you take more than the prescribed dose.

At a glance

  • Quinine is a medicine used to treat night-time leg cramps that disrupt sleep or are very painful.

  • It is usually prescribed if other treatments like stretching have not worked.

  • Take one tablet at bedtime and keep a diary to see how well it is working.

  • Quinine can cause side-effects; tell your doctor if you experience any.

  • Avoid tonic water and other drinks containing quinine while taking this medicine.

  • If you have certain conditions or take other medicines, tell your doctor before starting quinine.

  • If you suspect an overdose or accidental ingestion, seek immediate medical help.

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About quinine

Tipo de medicamento

An antimalarial medicine

Usado para

Treatment of night-time leg cramps

También llamado

Quinine bisulfate, quinine dihydrochloride, quinine sulfate

Disponible como

Comprimidos

You may be prescribed quinine for cramps in the leg if the cramps regularly disrupt your sleep, or are very painful. Taking quinine is generally only recommended if other treatments (such as stretching exercises and massaging the affected muscle) have been tried first and not been successful.

Quinine is likely to reduce the number and/or the severity of your leg cramps, but it may not stop them altogether. When quinine is first prescribed it will be done on a trial basis for a few weeks, as it may take this amount of time for you to start to feel the benefit. You can assess how well the quinine is working for you, by keeping a sleep and cramp diary. Make a note of how often you get cramp and how severe it is for a few weeks before you start treatment, and then compare this with episodes of cramp after the start of treatment.

Quinine can sometimes cause side-effects (some of which may be serious) so you should also check for any unwanted effects it is having on you. If quinine helps you then you may be advised to continue with it for a few months. You should, however, consider stopping quinine every three months or so. This is because, in some people, the cramps go away and so the treatment may no longer be needed.

Quinine is also used to treat malaria infection. For information about this please see the alternative medicine leaflet Quinine for malaria.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking quinine it is important that your doctor knows:

  • Si estás embarazada, intentando tener un bebé o amamantando.

  • If you have any problems with your eyes, or with your hearing.

  • If you have a heart condition, such as an irregular heart rhythm.

  • If you have any problems with the way your kidneys work, or any problems with the way your liver works.

  • If you have blood in your urine.

  • If you have been told you have an imbalance of salt levels in your blood.

  • Si tienes una condición que causa debilidad muscular, llamada miastenia gravis.

  • Si tienes deficiencia de glucosa-6-fosfato deshidrogenasa. Este es un trastorno genético donde hay una falta de una enzima a menudo conocida como G6PD. Las personas con este trastorno tienen problemas después de comer alimentos como habas.

  • Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.

  • If you have ever had an allergic reaction to a medicine, or if you have had a bad reaction to quinine in tonic water or any other soft drink.

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  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about quinine and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take quinine exactly as your doctor tells you to. It is usual to take one tablet (of either 200 mg or 300 mg) at bedtime. Your dose will be printed on the label of the pack to remind you about what the doctor said. Do not take more than the prescribed amount.

  • Swallow the tablet with a drink of water.

  • If you forget to take a dose, do not worry, just skip the missed dose and take your next dose on the following evening as usual. Do not take two doses together to make up for a forgotten dose.

  • Remember to keep your regular appointments with your doctor. This is so your doctor can check on your progress. You may need to take quinine for about four weeks before you feel the full benefit.

  • Your doctor will discuss with you the possibility of unwanted side-effects of the treatment. It is important that you let your doctor know as soon as possible if you experience any of the following: impaired hearing, ringing noises in your ear, headaches, feeling sick, or any problems with your eyesight.

  • Quinine is present in drinks such as tonic water and bitter lemon. It is probably best to avoid these drinks while you are on quinine.

  • Never take more than the prescribed dose. Taking too much quinine can cause serious problems. Also, quinine is dangerous if it is taken by a child, so keep the tablets away from children. If you suspect that someone has taken an overdose of quinine or has swallowed some by accident, you must contact a doctor de inmediato. Alternatively, go to the accident and emergency department of a local hospital. No se demore. Lleve el recipiente con usted, incluso si está vacío. Esto es para que el médico sepa qué se ha tomado.

  • If you buy any medicines, always check with a pharmacist that they are suitable to take with your other medicines. This is because some medicines (such as cimetidine which is taken for heartburn) can interfere with quinine and increase the risk of serious side-effects.

  • If you have diabetes you may need to check your blood glucose more frequently, as quinine can affect the level of sugar in your blood. Your doctor will be able to advise you about this.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with quinine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Although side-effects are uncommon when quinine is used to treat leg cramps, serious side-effects do still sometimes occur. Contact your doctor for advice as soon as possible if you experience any of the following:

Quinine side-effects


¿Qué puedo hacer si experimento esto?

Diarrhoea, feeling sick (nausea), feeling weak or confused, 'ringing' in your ears, headache, having a spinning sensation (vertigo)

Tell your doctor as soon as possible

Difficulties seeing, such as blurred vision and colour changes

Tell your doctor as soon as possible. Do not drive while your vision is affected

Hot and flushed skin, rashes, muscle weakness, increased sensitivity to light

Si alguno de estos se vuelve problemático, informe a su médico

Difficulty breathing, swelling around your mouth or face

Speak with your doctor straightaway - these are signs of an allergy to quinine

Unexplained bleeding, unusual bruising, sore throats or infections

Tell your doctor as soon as possible - these could be signs of a serious blood disorder and your doctor will want to check for this

Si experimenta cualquier otro síntoma que crea que puede deberse a las tabletas, por favor hable con su médico o farmacéutico para obtener más consejos.

  • Mantenga todos los medicamentos fuera del alcance y la vista de los niños.

  • Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.

Información importante sobre todos los medicamentos

Si vas a someterte a una operación o tratamiento dental, informa a la persona que realiza el tratamiento sobre los medicamentos que estás usando.

Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.

No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.

Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.

Informar efectos secundarios de un medicamento o vacuna

Si experimenta efectos secundarios, puede reportarlos en línea a través de Yellow Card website.

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Preguntas frecuentes

How soon can I expect to feel the benefits of taking quinine for my leg cramps?

When you are first prescribed quinine, it’s given on a trial basis because it can take a few weeks for the medication to start working effectively. To gauge its effectiveness, you can track your cramps before and after starting treatment with a sleep and cramp diary.

Is it possible to stop taking quinine if my leg cramps improve?

Yes, you should consider stopping quinine periodically, typically every three months or so. This is because some people find their cramps go away, meaning the treatment may no longer be necessary.

Are there any specific drinks I should avoid while taking quinine?

Yes, quinine is present in tonic water and bitter lemon. It is generally best to avoid these drinks while you are taking quinine medication.

What should I do if I accidentally miss a dose of quinine?

If you forget to take a dose, you should skip the missed dose. Then, simply take your next dose on the following evening at your usual time. Do not take two doses together to compensate for a forgotten one.

Can quinine interact with other medications, even those I buy without a prescription?

Yes, some medicines, including those available without a prescription and herbal remedies, can interact with quinine. For instance, cimetidine, which is used for heartburn, can increase the risk of serious side-effects when taken with quinine. Always check with a pharmacist about any other medicines you buy to ensure they are suitable to take with quinine.

I have diabetes. Will taking quinine affect my blood sugar levels?

If you have diabetes, quinine can affect your blood sugar levels. You may need to check your blood glucose more frequently. Your doctor will be able to provide specific advice on managing this.

What should I do if a child accidentally swallows quinine tablets?

Quinine is dangerous if taken by a child. If you suspect that a child has swallowed quinine tablets by accident, you must contact a doctor straightaway or go to the accident and emergency department of a local hospital without delay. Take the medicine container with you so doctors know what has been taken.

Lecturas adicionales y referencias

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Historial del artículo

La información en esta página está escrita y revisada por pares por clínicos calificados.

  • Next review due: 17 Apr 2027
  • 16 de mayo de 2024 | Última versión

    Última actualización por

    Michael Stewart, MRPharmS

    Revisado por pares por

    Sid Dajani
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