Nitrofurantoína para las infecciones de orina
Macrobid
Revisado por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 5 abr 2025
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Take nitrofurantoin with (or just after) a meal or a snack. This will help your body to absorb the medicine and help to prevent stomach upset.
Space out your doses evenly throughout the day, and remember to finish the course prescribed.
Nitrofurantoin can darken the colour of your urine. This is nothing to worry about.
Contact your doctor if you develop a cough with difficulty breathing and pains in your chest during treatment with nitrofurantoin.
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About nitrofurantoin
Tipo de medicamento | An antibacterial |
Utilizado para | Urinary tract infection (UTI) in adults and in children over 3 months of age |
También llamado | Macrobid® |
Disponible como | Tablets, capsules, prolonged-release capsules, oral liquid medicine |
A urine infection is often called a urinary tract infection (or simply, UTI) by doctors. Most urine infections are caused by germs (bacteria) that come from your own bowel. They are usually easily treated with a short course of an antibacterial medicine such as nitrofurantoin. Occasionally, longer-term treatment is needed to prevent infections from coming back. Nitrofurantoin works by killing the bacteria causing the infection.
Before taking nitrofurantoin
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking nitrofurantoin it is important that your doctor knows:
If you are pregnant or breastfeeding. Although nitrofurantoin can be taken during pregnancy, it is still important that you tell your doctor about being pregnant.
Si tiene algún problema con el funcionamiento de su hígado, o si tiene algún problema con el funcionamiento de sus riñones.
Si padece diabetes (diabetes mellitus).
If you have been told you have anaemia, or if you have low levels of vitamin B or folic acid.
Si tiene problemas respiratorios.
If you have a problem where your nerves cause pain or numbness, called peripheral neuropathy.
If you have been told you have one of the following rare inherited conditions: porphyria or glucose-6-phosphate dehydrogenase (G6PD) deficiency.
Si está tomando otros medicamentos. Esto incluye todos los medicamentos que se pueden comprar sin receta, así como las hierbas medicinales y los medicamentos complementarios.
Si alguna vez ha tenido una reacción alérgica a un medicamento.
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How to take nitrofurantoin
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about nitrofurantoin, and will also provide you with a full list of the side-effects which you could experience from taking it.
Take nitrofurantoin exactly as your doctor tells you to. Your dose will depend upon whether you are being treated because you have an infection, or to prevent an infection from coming back. The directions for taking your doses will be printed on the label of the pack to remind you about what the doctor said to you.
Take each of your doses with a snack or after eating a meal. Space them out evenly throughout the day - this means that tablets/capsules prescribed four times a day should ideally be taken every six hours, those prescribed twice a day should be taken every 12 hours, and those prescribed once a day should be taken every 24 hours.
Keep taking nitrofurantoin until the course is finished. It is important you do this even if you feel well, otherwise your infection may come back. Most people taking nitrofurantoin are prescribed a short course of treatment which usually lasts between 3-7 days. If you have had several urine infections in a short period of time, your doctor will prescribe a longer course of treatment for you, often for six months.
Si olvida tomar una dosis a la hora habitual, tómela en cuanto se acuerde. Intente tomar el número correcto de dosis al día, pero no tome dos dosis al mismo tiempo para compensar la dosis olvidada.
Aproveche al máximo su tratamiento
Most people improve within a few days of starting treatment. If your symptoms do not improve despite taking nitrofurantoin, go back to see your doctor, as you may need an alternative antibiotic. This is because some bacteria are resistant to some types of antibiotics.
Nitrofurantoin can turn your urine a yellow/brown colour. This is harmless.
If you buy any medicines, check with a pharmacist that they are suitable for you to take with nitrofurantoin. Some antacids can interfere with nitrofurantoin and stop it from working properly.
If you are taking the contraceptive 'pill' at the same time as this antibiotic, the effectiveness of the 'pill' can be reduced if you have a bout of sickness (vomiting) or diarrhoea which lasts for more than 24 hours. If this should happen, ask your doctor or pharmacist for advice about what additional contraceptive precautions to use over the following few days. There is no need to use additional precautions for any bouts of sickness or diarrhoea which last for less than 24 hours.
If you are due to have any medical or dental treatment, tell the person carrying out the treatment that you are taking nitrofurantoin. This is because it can affect the results of some diagnostic tests.
Nitrofurantoin can stop the oral typhoid vaccine from working. If you are due to have any vaccinations while you are taking nitrofurantoin, please make sure the person treating you knows that you are taking it.
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Can nitrofurantoin cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with nitrofurantoin. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Nitrofurantoin side-effects | ¿Qué puedo hacer si me ocurre esto? |
Sentirse mal (náuseas) o estar enfermo (vómitos), pérdida de apetito | Stick to simple foods - avoid fatty or spicy meals. Remember to take nitrofurantoin with food |
Diarrea | Beber mucha agua para reponer los líquidos perdidos |
Sensación de mareo o sueño | No conduzca ni utilice herramientas o máquinas mientras esté afectado |
Itchy rash, allergic-type reactions, swollen salivary glands | Speak with your doctor or a pharmacist for further advice |
Important: your doctor will have discussed with you the possibility of a less common side-effect that may affect your lungs. You should let your doctor know straightaway if you experience any of the following:
Any difficulty breathing, pains in your chest, coughing, chills, or a high temperature (fever).
Si experimenta cualquier otro síntoma que considere que puede deberse al medicamento, consulte a su médico o farmacéutico.
How to store nitrofurantoin
Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
The liquid medicine lasts for 30 days after first opening.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
No tome nunca más de la dosis prescrita. Si sospecha que usted u otra persona ha tomado una sobredosis de este medicamento, acuda inmediatamente al servicio de urgencias de su hospital. Llévese el envase, aunque esté vacío.
Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.
No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.
Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.
Informar de los efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede notificarlos en línea a través del sitio web de la Tarjeta Amarilla.
Lecturas complementarias y referencias
- Manufacturer's PIL; Nitrofurantoin 100 mg Prolonged-Release Capsules, ADVANZ Pharma (formerly Amdipharm Mercury Company Limited), The electronic Medicines Compendium. Dated December 2023
- Manufacturer's PIL, Nitrofurantoin 50 mg and 100 mg Capsules; ADVANZ Pharma (formerly Amdipharm Mercury Group Limited), The electronic Medicines Compendium. Dated January 2024.
- Manufacturer's PIL, Nitrofurantoin 25 mg/5 ml Oral Suspension; ADVANZ Pharma, The electronic Medicines Compendium. Dated January 2024.
- Medicamentos BNF completa 89ª edición; Asociación Médica Británica y Real Sociedad Farmacéutica de Gran Bretaña, Londres.
Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
Fecha prevista para la próxima revisión: 5 abr 2028
5 abr 2025 | Última versión

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