Nitrofurantoína para las infecciones de orina
Macrobid
Peer reviewed by Dr Colin Tidy, MRCGPLast updated by Michael Stewart, MRPharmSLast updated 5 Apr 2025
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Take nitrofurantoin with (or just after) a meal or a snack. This will help your body to absorb the medicine and help to prevent stomach upset.
Space out your doses evenly throughout the day, and remember to finish the course prescribed.
Nitrofurantoin can darken the colour of your urine. This is nothing to worry about.
Contact your doctor if you develop a cough with difficulty breathing and pains in your chest during treatment with nitrofurantoin.
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About nitrofurantoin
Tipo de medicamento | An antibacterial |
Utilizado para | Urinary tract infection (UTI) in adults and in children over 3 months of age |
También llamado | Macrobid® |
Disponible como | Tablets, capsules, prolonged-release capsules, oral liquid medicine |
What is nitrofurantoin used for?
Nitrofurantoin is a type of antibiotic used to treat urinary tract infections (UTIs) in adults and children over 3 months.
Most UTIs are caused by germs (bacteria) that come from your own bowel. They are usually easily treated with a short course of an antibacterial medicine such as nitrofurantoin.
Occasionally, longer-term treatment is needed to prevent infections from coming back. Nitrofurantoin works by killing the bacteria causing the infection.
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Side effects of nitrofurantoin
Common side effects of nitrofurantoin are:
Me siento mal.
Estar enfermo.
Pérdida de apetito.
Feeling dizzy or sleepy.
Itchy rash.
Encontrará una lista completa en el prospecto del fabricante que acompaña al medicamento.
Los efectos no deseados suelen mejorar a medida que su organismo se adapta al nuevo medicamento, pero hable con su médico o farmacéutico si alguno de los siguientes continúa o se vuelve molesto.
How to manage nitrofurantoin side effects
Nitrofurantoin side effects | ¿Qué puedo hacer si me ocurre esto? |
Sentirse mal (náuseas) o estar enfermo (vómitos), pérdida de apetito | Stick to simple foods - avoid fatty or spicy meals. Remember to take nitrofurantoin with food |
Diarrea | Beber mucha agua para reponer los líquidos perdidos |
Sensación de mareo o sueño | No conduzca ni utilice herramientas o máquinas mientras esté afectado |
Itchy rash, allergic-type reactions, swollen salivary glands | Speak with your doctor or a pharmacist for further advice |
Important: your doctor will have discussed with you the possibility of a less common side effect that may affect your lungs. You should let your doctor know straightaway if you experience any of the following:
Any difficulty breathing, pains in your chest, coughing, chills, or a high temperature (fever).
Si experimenta cualquier otro síntoma que considere que puede deberse al medicamento, consulte a su médico o farmacéutico.
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Who should not take nitrofurantoin
Some medicines aren’t suitable for certain health conditions or may require extra care. Before taking nitrofurantoin, it is important to let your doctor know:
If you are pregnant or breastfeeding. Although nitrofurantoin can be taken during pregnancy, it is still important that you tell your doctor about being pregnant.
Si tiene algún problema con el funcionamiento de su hígado, o si tiene algún problema con el funcionamiento de sus riñones.
Si padece diabetes (diabetes mellitus).
If you have been told you have anaemia, or if you have low levels of vitamin B or folic acid.
Si tiene problemas respiratorios.
If you have a problem where your nerves cause pain or numbness, called peripheral neuropathy.
If you have been told you have one of the following rare inherited conditions: porphyria or glucose-6-phosphate dehydrogenase (G6PD) deficiency.
Si está tomando otros medicamentos. Esto incluye todos los medicamentos que se pueden comprar sin receta, así como las hierbas medicinales y los medicamentos complementarios.
Si alguna vez ha tenido una reacción alérgica a un medicamento.
How to take nitrofurantoin
Read the information leaflet in the pack before starting. It explains nitrofurantoin and its possible side effects.
Take nitrofurantoin exactly as your doctor instructs. Your dose depends on whether it’s for treating or preventing an infection. Follow the label instructions.
Take each dose with food or a snack. Space doses evenly: four times a day = every 6 hours, twice a day = every 12 hours, once a day = every 24 hours.
Finish the full course, even if you feel well, to prevent the infection from returning. Most courses last 3-7 days; for frequent urine infections, treatment may last up to six months.
If you forget a dose, take it as soon as you remember. Do not take two doses at once to make up for a missed one.
Aproveche al máximo su tratamiento
Most people feel better within a few days. If your symptoms don’t improve, see your doctor as you may need a different antibiotic.
Nitrofurantoin can turn your urine yellow or brown. This is harmless.
Check with a pharmacist before taking any other medicines. Some antacids can stop nitrofurantoin from working properly.
If you take the contraceptive pill, its effectiveness may be reduced if you have vomiting or diarrhoea lasting more than 24 hours. Ask your doctor or pharmacist about extra precautions.
Tell your doctor or dentist that you are taking nitrofurantoin before any treatment, as it can affect some tests.
Nitrofurantoin can stop the oral typhoid vaccine from working. Inform your healthcare provider if you are due for any vaccinations.
How to store nitrofurantoin
Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
The liquid medicine lasts for 30 days after first opening.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
No tome nunca más de la dosis prescrita. Si sospecha que usted u otra persona ha tomado una sobredosis de este medicamento, acuda inmediatamente al servicio de urgencias de su hospital. Llévese el envase, aunque esté vacío.
Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.
No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.
Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.
Informar de los efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede notificarlos en línea a través del sitio web de la Tarjeta Amarilla.
Preguntas más frecuentes
How long does it take for nitrofurantoin take to work on a UTI?
Most people start to feel better within 2-3 days of taking nitrofurantoin for a UTI. Burning and urgency often improve first, while bladder pressure or discomfort may take a bit longer. Always finish the full course, even if you feel better.
Is nitrofurantoin safe to take during pregnancy?
Nitrofurantoin is generally considered safe to take during pregnancy, especially in the 2nd and 3rd trimesters. However, it’s usually avoided close to delivery (around weeks 38-42) as it may affect the baby’s red blood cells.
Can you drink alcohol on nitrofurantoin?
Yes, you can drink alcohol in moderation while taking nitrofurantoin as alcohol does not interfere with how it works. However, drinking too much can make side effects such as nausea, dizziness, or stomach upset feel worse.
What should you avoid while taking nitrofurantoin?
When taking nitrofurantoin, you should avoid taking antacids containing magnesium trisilicate as they can reduce how well the medicine works.
Does nitrofurantoin make you urinate more?
No, nitrofurantoin does not make you urinate more. If you feel like you’re peeing more often, it is usually because of the UTI itself, not the medication.
Does nitrofurantoin contain penicillin?
No, nitrofurantoin does not contain penicillin. It is a different type of antibiotic used mainly to treat urinary tract infections and works differently from penicillin.
Lecturas complementarias y referencias
- Manufacturer's PIL; Nitrofurantoin 100 mg Prolonged-Release Capsules, ADVANZ Pharma (formerly Amdipharm Mercury Company Limited), The electronic Medicines Compendium. Dated December 2023
- Manufacturer's PIL, Nitrofurantoin 50 mg and 100 mg Capsules; ADVANZ Pharma (formerly Amdipharm Mercury Group Limited), The electronic Medicines Compendium. Dated January 2024.
- Manufacturer's PIL, Nitrofurantoin 25 mg/5 ml Oral Suspension; ADVANZ Pharma, The electronic Medicines Compendium. Dated January 2024.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
Próxima revisión prevista: 5 de abril 2028
5 Abr 2025 | Última versión

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