Midodrina para la hipotensión postural
Bramox
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 15 Abr 2023
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Taking midodrine will raise your blood pressure to help stop you feeling dizzy or faint. To begin with you will need to be monitored closely to make sure your blood pressure doesn't go too high.
Do not take a dose of midodrine too late in the evening - your last dose of the day should be taken at least four hours before your bedtime.
While being treated with midodrine, try to keep your head raised slightly when lying down in bed, for instance by using extra pillows. This helps to reduce the risk of having high blood pressure when lying down.
De un vistazo
Midodrine is a medicine used to treat low blood pressure when standing up.
It helps prevent dizziness, faintness, or falls caused by postural hypotension.
You typically take it three times a day, but not late in the evening.
Your doctor will check your blood pressure regularly while you are taking it.
Possible side-effects include pain when passing urine, goosebumps, or itchy scalp.
Tell your doctor if you experience chest pain, headaches, or blurred vision.
About midodrine
Tipo de medicamento | An alpha-adrenergic sympathomimetic medicine (alpha-agonist) |
Usado para | Postural hypotension (low blood pressure when standing) due to autonomic nervous system dysfunction |
También llamado | Bramox® |
Disponible como | Comprimidos |
Midodrine is used to treat the problem of having low blood pressure when standing up from a sitting position or when already standing. This condition is known as postural hypotension, or alternatively, orthostatic hypotension. A drop in your blood pressure when you stand up can make you feel dizzy and light-headed, or cause you to faint. This can also put you at risk of falling over. Other symptoms include blurred vision, weakness or tiredness (fatigue), feeling sick (nausea) a fast heartbeat (palpitations) and headaches.
Postural hypotension can have a number of underlying causes. It may be caused by taking certain medicines or if you become lacking in fluid in the body (dehydrated) due to being sick (vomiting) or having diarrhoea. If this is the case, standing up slowly or sitting upright first before standing may help to manage your symptoms. Postural hypotension may also be caused by an underlying problem with your nervous system such as enfermedad de Parkinson o neuropatía periférica.
Midodrine is used when severe symptoms are being caused by a problem with your nervous system and other forms of treatment have not helped. It works by stimulating certain parts of your nervous system (alpha receptors) which has the effect of narrowing your blood vessels. As your blood vessels narrow, your blood pressure goes up. This helps stop any dizziness or fainting when you stand up.
Before taking midodrine tablets
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking midodrine it is important that your doctor knows:
Si estás embarazada, intentando concebir o amamantando.
Si tienes presión arterial alta (hipertensión).
If you have been told you have a disorder of the nervous system.
If you have a heart condition or any problems with your blood vessels.
If you have any problems with your prostate gland or if you have difficulty passing urine.
If you have any problems with the way your kidneys or liver work.
If you have glaucoma, a condition which causes raised pressure in the eye(s).
If you have diabetes mellitus, a condition which raises your blood sugar levels. In particular, if your diabetes has caused any problems with your vision.
Si tienes una glándula tiroides hiperactiva (hipertiroidismo).
Si tienes un tumor en la glándula suprarrenal, llamado feocromocitoma.
Si alguna vez has tenido una reacción alérgica a un medicamento.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
How to take midodrine tablets
Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The manufacturer's leaflet will give you more information about midodrine and a full list of side-effects which you may experience from taking it.
Take midodrine exactly as your doctor tells you to. Your dose will be written on the label of your pack to remind you.
The usual starting dose is one 2.5 mg tablet taken three times a day. Your blood pressure will need to be monitored and your dose may be increased each week until you find the lowest dose that controls your blood pressure. The maximum dose is 10 mg three times a day.
Swallow the tablets with a drink of water. It is not important whether you take your dose before or after food.
Do not take a dose of midodrine late in the evening, take your last dose of the day at least four hours before your bedtime.
If you forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose or unless it is within four hours of your bedtime. In these cases leave out the forgotten dose and take your next dose when it is due. Do not take two doses together to make up for a forgotten dose.
Obteniendo el máximo de tu tratamiento
Intenta mantener todas tus citas regulares con tu médico. Esto es para que tu médico pueda revisar tu progreso.
Your blood pressure may need to be monitored when you are lying down and when you are standing up. This is to make sure your blood pressure does not go too high when you are lying down. If your blood pressure does go up when you are lying down then your dose of midodrine may need to be reduced.
You may find it useful to have a blood pressure meter to use at home. Ask your doctor or pharmacist for advice about testing your blood pressure at home.
When you are lying down in bed try to keep your head raised - for instance, by using extra pillows. This is to help prevent your blood pressure going too high when you are lying down.
If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking midodrine.
If you buy any medicines, check with your doctor or a pharmacist that they are suitable for you to take with midodrine.
Can midodrine tablets cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with midodrine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common midodrine side-effects (these affect more than 1 in 10 people) | ¿Qué puedo hacer si experimento esto? |
Pain when passing urine | Informe a su médico sobre esto |
Goosebumps, itchy scalp | If either of these become troublesome, let your doctor know |
Common midodrine side-effects (these affect fewer than 1 in 10 people) | ¿Qué puedo hacer si experimento esto? |
Feeling sick (nausea), indigestion or heartburn (reflux) | Mantente con comidas simples - evita alimentos ricos o picantes |
Raised blood pressure when lying down | Using a blood pressure meter at home may help to identify this. Let your doctor know if you have any concerns |
Dolor de cabeza | Let your doctor know if you experience repeated headaches, especially if you also have blurred vision (see below) |
Difficulty passing urine | Informe a su médico sobre esto |
Chills, tingling or itchy skin, skin flushing, skin rash, swollen or painful lining of the mouth | If any of these become troublesome let your doctor know |
Importante: taking midodrine may cause your blood pressure to go too high. This can be a particular problem if it happens when you are lying down. Your dose may need to be reduced or your treatment stopped. Your doctor will monitor your blood pressure and it may also help to use a blood pressure meter at home.
Let your doctor know if you think your blood pressure is too high or if you experience symptoms such as:
Dolor en el pecho
A fast heartbeat (palpitations)
Falta de aliento
Dolores de cabeza
Visión borrosa
Si experimenta otros síntomas que cree que pueden deberse a este medicamento, hable con su médico o farmacéutico.
How to store midodrine tablets
Mantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Midodrine tablets that are packaged in a bottle must be used within eight weeks of opening the bottle.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Sitio web de Yellow Card.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Preguntas frecuentes
Can midodrine cause fatigue?
The article mentions that postural hypotension, the condition midodrine treats, can cause weakness or tiredness (fatigue). However, fatigue is not listed as a side-effect of midodrine itself.
Does midodrine cause sleepiness?
Sleepiness is not listed as a common or very common side-effect of midodrine in the provided article. The article does mention, however, that your last dose of the day should be taken at least four hours before bedtime, to avoid your blood pressure going too high when lying down.
How long does midodrine take to work?
The article states that your dose of midodrine may be increased each week until the lowest dose that controls your blood pressure is found. This implies that the full therapeutic effect might take some time as the dosage is adjusted.
Are there specific times of day I should avoid taking midodrine?
Yes, you should not take a dose of midodrine late in the evening. Your last dose of the day should be taken at least four hours before your bedtime to prevent your blood pressure from becoming too high while you are lying down.
Lecturas adicionales y referencias
- Manufacturer's PIL, Bramox® 2.5 mg, 5 mg and 10 mg tablets; Brancaster Pharma Ltd, The electronic Medicines Compendium. Dated December 2021.
Sobre el autorVer biografía completa

Michael Stewart, MRPharmS
Gerente de Revisión de Folletos de Medicamentos – Contratista, Farmacéutico
BPharm (Hons), MRPharmS
Michael es un farmacéutico comunitario que ejerce en Midlands y South Yorkshire con más de 20 años de experiencia asesorando sobre medicamentos y condiciones médicas. Tiene una sólida formación en capacitación en atención médica, habiendo producido e impartido cursos de formación para equipos de farmacia y personal de entornos de atención residencial, incluidas enfermeras. También ha contribuido a juntas asesoras de farmacia para la gestión de condiciones de baja gravedad en la comunidad.
Acerca del revisor

Sid Dajani
Sultan Dajani se graduó en la Escuela de Farmacia de Londres en 1994 y se convirtió en el miembro más joven elegido para el consejo de la Sociedad Real de Farmacia desde su fundación en 1842.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Artículo también disponible en Inglés, Alemán, Español, Francés, Italiano, Portugués, Hindi, Hebreo, Árabe, y Sueco.
Próxima revisión: 13 de octubre de 2027
15 Abr 2023 | Última versión
3 May 2017 | Publicado originalmente
Escrito por:
Michael Stewart, MRPharmS

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