Tabletas de metilprednisolona
Medrone
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 21 de septiembre de 2022
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Methylprednisolone belongs to a class of medicines known as corticosteroids (more commonly called steroids).
Your pharmacist will give you a blue 'Steroid Treatment Card'. Carry this with you at all times.
Take methylprednisolone tablets with food.
If you need any medical treatment, make sure the person treating you knows you are taking methylprednisolone. This is because your dose may need to be increased for a short while.
De un vistazo
Methylprednisolone is a corticosteroid medicine used to treat many allergic and inflammatory conditions.
It works by interfering with chemicals in your body that cause inflammation.
Take your tablets once daily with food, usually at breakfast time.
Do not stop taking methylprednisolone suddenly; your doctor will need to reduce your dose gradually.
Carry a Steroid Treatment Card if your course of treatment lasts more than three weeks.
See your doctor straight away if you become ill or think you have been in contact with chickenpox, measles, or shingles.
About methylprednisolone
Tipo de medicamento | A corticosteroid medicine |
Usado para | Allergic and inflammatory conditions |
También llamado | Medrone®; Depo-Medrone®; Solu-Medrone® |
Disponible como | Tabletas y inyección |
Methylprednisolone tablets belong to a group of medicines called corticosteroids. It is sometimes referred to simply as an oral steroid. Esteroides orales are used to treat a wide variety of conditions. Some examples include inflammatory bowel diseases (for example, enfermedad de Crohn, colitis ulcerosa), autoimmune diseases (for example, lupus eritematoso sistémico (LES), sarcoidosis), joint and muscle diseases (for example, artritis reumatoide), and alimentarias. They are also used to treat some cancers.
Methylprednisolone works in part by interfering with the release of certain chemicals in your body which cause inflammation.
Methylprednisolone is also available in the form of an injection. Some types of injection are used when treatment is needed quickly, or a person is unable to swallow tablets. Other types of injection are given to relieve inflammation in a specific area, such as a painful or swollen joint. This leaflet gives advice for people taking methylprednisolone tablets.
Before taking methylprednisolone
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking methylprednisolone it is important that your doctor knows:
Si tienes presión arterial alta (hipertensión).
If you have had a heart attack, or if you have any other heart problems.
Si tienes algún problema con el funcionamiento de tu hígado, o si tienes algún problema con el funcionamiento de tus riñones.
If you (or a close family member) have either diabetes or an eye condition called glaucoma.
If you have any of the following conditions: an underactive thyroid, 'thinning' of the bones (osteoporosis), epilepsy, a condition causing muscle weakness (called myasthenia gravis), a stomach ulcer, or a bowel disorder.
Si alguna vez has tenido un problema de salud mental.
If you are pregnant or breastfeeding. (Oral steroids like methylprednisolone can be taken while you are expecting or breastfeeding; however, it is important that your doctor knows about the baby.)
If you have any kind of infection at the moment, or if you have ever had tuberculosis (TB).
If you have ever had an unwanted blood clot in an artery or a vein.
If you have recently had, or are about to have, any vaccinations.
If you are taking other medicines. This includes any medicines which are available to buy without a prescription, as well as herbal and complementary medicines.
If you have ever had an allergic reaction to a medicine, or if you have ever developed muscle pain after taking a steroid medicine.
How to take methylprednisolone tablets
Before starting the treatment, read the manufacturer's printed information leaflet from inside the pack and any additional information you are given by your doctor. These will give you more information about methylprednisolone and will also provide you with a full list of side-effects which you could experience from taking it.
Your doctor or pharmacist will tell you how many tablets to take for each dose. It is usual to take methylprednisolone once daily at breakfast-time. If you have been told otherwise, you must take the tablets exactly as you have been told by your doctor.
Take methylprednisolone with food. Swallow the tablet with a drink of water.
If you forget to take a dose at your usual time, take it as soon as you remember (with something to eat). If you do not remember until the following day, leave out the missed dose. Do not take two doses together to make up for a forgotten dose.
Continue to take methylprednisolone until your doctor tells you to stop. Stopping taking the tablets suddenly can cause problems so your doctor will want you to reduce your dose gradually over a period of time if/when this becomes necessary.
Obteniendo el máximo de tu tratamiento
If your course of treatment is due to last more than three weeks, you will be given a 'Steroid Treatment Card' which says that you are on steroids and contains some important advice for you. It is important that you read this card and carry it with you at all times. It also contains details about your dose, how long you have been taking methylprednisolone for, and who prescribed it for you. Please make sure that this information is kept up to date. If you are having an operation or dental treatment or any treatment for an injury, tell the person carrying out the treatment that you are taking methylprednisolone and show them your treatment card. This is because your dose may need adjusting.
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. Your doctor will want you to have tests from time to time to make sure you remain free from some of the unwanted side-effects of treatment.
There are several strengths of methylprednisolone tablets available: 2 mg, 4 mg, 16 mg, and 100 mg. Each time you collect a new supply of tablets from your pharmacy, check to see if the tablets are the same as before. If they are different, speak with your pharmacist who will check it out for you.
Methylprednisolone can suppress your immune system, so it is important if you become ill that you make an appointment to see your doctor straightaway. Also, if you come into contact with anyone who has measles, shingles or chickenpox (or anyone who suspects they might have them), you must see your doctor as soon as possible.
Some vaccines are not suitable for you while you are being treated with methylprednisolone. If you need any immunisations, make sure you mention that you are taking an oral steroid.
It is best not to drink grapefruit juice while you are on methylprednisolone. This is because a chemical in grapefruit juice is thought to increase the amount of methylprednisolone in your bloodstream, and could make side-effects more likely.
If you buy any medicines, check with your pharmacist that they are suitable to take with methylprednisolone.
Can methylprednisolone cause problems?
Along with its useful effects, methylprednisolone can cause unwanted side-effects which your doctor will discuss with you. The benefits of taking an oral steroid usually outweigh the side-effects; however, they can sometimes be troublesome. The table below contains some of the most common ones associated with methylprednisolone. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below.
Although not everyone experiences side-effects, and some will improve as your body adjusts to the new medicine, speak with your doctor or pharmacist if you become concerned about any of the following:
Común methylprednisolone side-effects | ¿Qué puedo hacer si experimento esto? |
Tummy (abdominal) pain, indigestion, feeling sick (nausea) | Stick to simple foods. If you are sick (vomit) and there is blood present, you must speak with your doctor straightaway |
Muscle weakness or feeling tired | No conduzca ni utilice herramientas o máquinas mientras esté afectado |
Mood or behavioural changes, especially at the beginning of treatment | If you become confused, irritable or start having worrying thoughts about harming yourself, speak with your doctor straightaway |
Difficulties sleeping, headache, increased weight, and irregular periods in women | Si alguno de estos se vuelve problemático, hable con su médico |
Increased risk of getting an infection | If you become ill, make an appointment to see your doctor straightaway |
Long-term treatment with methylprednisolone may cause other unwanted effects | If you have any symptoms which are causing you concern, you should arrange to see your doctor for advice |
Importante: you should let your doctor know if you start to experience blurred vision or other vision problems whilst taking methylprednisolone.
For more information about side-effects which are possible when methylprednisolone is taken long-term, see the separate leaflet called Oral Steroids.
How to store methylprednisolone tablets
Mantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Sitio web de Yellow Card.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Preguntas frecuentes
Can I take all my methylprednisolone tablets at once in the morning?
Yes, it is common to take methylprednisolone once daily at breakfast-time. However, you should always follow the specific instructions given by your doctor regarding how many tablets to take for each dose and when to take them.
Why would my doctor prescribe methylprednisolone given the potential side-effects?
Methylprednisolone is prescribed to treat a wide range of conditions, including various allergic reactions and inflammatory diseases. Your doctor will have discussed the potential side-effects with you, and generally, the benefits of taking an oral steroid like methylprednisolone are considered to outweigh the risks from its side-effects.
I'm told to take this with food. Does it matter what kind of food?
Yes, it is important to take methylprednisolone with food. You should generally stick to simple foods if you experience tummy pain, indigestion, or nausea. Additionally, you should avoid drinking grapefruit juice as it is thought to increase the amount of methylprednisolone in your bloodstream, potentially making side-effects more likely.
I'm worried about getting infections while taking this medicine. What should I do?
Methylprednisolone can suppress your immune system, increasing your risk of infection. If you become ill, you should make an appointment to see your doctor straightaway. Also, if you come into contact with anyone who has measles, shingles, or chickenpox (or suspects they might have them), you must see your doctor as soon as possible.
What should I do if I think I've taken too much methylprednisolone?
Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, you should go to the accident and emergency department of your local hospital immediately. Remember to take the medicine container with you, even if it is empty.
Lecturas adicionales y referencias
- Manufacturer's PIL, Medrone® Tablets 2 mg, 4 mg; Pfizer Limited, The electronic Medicines Compendium. Dated November 2018.
- Manufacturer's PIL, Medrone® 100 mg Tablets; Pfizer Limited, The electronic Medicines Compendium. Dated October 2020.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
Sobre el autorVer biografía completa

Michael Stewart, MRPharmS
Gerente de Revisión de Folletos de Medicamentos – Contratista, Farmacéutico
BPharm (Hons), MRPharmS
Michael es un farmacéutico comunitario que ejerce en Midlands y South Yorkshire con más de 20 años de experiencia asesorando sobre medicamentos y condiciones médicas. Tiene una sólida formación en capacitación en atención médica, habiendo producido e impartido cursos de formación para equipos de farmacia y personal de entornos de atención residencial, incluidas enfermeras. También ha contribuido a juntas asesoras de farmacia para la gestión de condiciones de baja gravedad en la comunidad.
Acerca del revisor

Sid Dajani
Sultan Dajani se graduó en la Escuela de Farmacia de Londres en 1994 y se convirtió en el miembro más joven elegido para el consejo de la Sociedad Real de Farmacia desde su fundación en 1842.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Artículo también disponible en Inglés, Alemán, Español, Francés, Italiano, Portugués, Hindi, Hebreo, Árabe, y Sueco.
Siguiente revisión prevista: 19 de marzo de 2027
21 de septiembre de 2022 | Última versión

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